No abstract available.
Dentures* ; Mucous Membrane*

Recent studies clearly demonstrated that the novel expression of LH gene in the rat testis, and suggested the local action of the LH-like molecule. The present study was performed to analyze the expression of the LH genes in the rat accessory reproductive organs. Expression of LH subunit genes in the rat uterus and epididymis was demonstrated by reverse transcription-polymerase chain reaction (RT-PCR) and specific LH radioimmunoassay (RIA). The LHbeta transcripts in these organs contained the published cDNA structure, the pituitary type exons 1-3, which encoded the entire LHbeta/ polypeptide. Presence of the transcripts for the alpha-subunit in the rat reproductive tissues were also confirmed by RT-PCR. In the LH RIA, significant levels of LH were detected in crude extracts from the rat ovary, uterus and epididymis. The competition cuties with increasing amount of tissue extracts were parallel with those of standard peptide, indicating that the immunoreactive LH-like materials in these tissues are similar to authentic pituitary LH molecule. In rat epididymis, the highest amount of immunoreactive LH was detected in corpus area. Our findings demonstrated that the genes for LH subunits are expressed in the rat accessory reproductive organs, and suggested that these extrapituitary LH may act as a local regulator with auto and/or paracrine manner.
Animals ; Complex Mixtures ; DNA, Complementary ; Epididymis* ; Exons ; Female ; Lutein* ; Luteinizing Hormone* ; Male ; Ovary ; Radioimmunoassay ; Rats* ; Testis ; Tissue Extracts ; Uterus*

It is still not well documented what the basic roles for the regulation of renin secretion from the kidney take place. Since the early study on the renal ischemia for the production of hypertension was introduced, the renin-angiotensin system has been regarded as the possible pathogenetic mechanism for the renovascular hypertension. The renin-angiotensin system, however, could be activated by various stimuli, such as, the changes of intrarenal perfusion pressure, the load or concentriation of sodium at the sites of macular densa, the changes of the sympathetic nervous activity and the changes of potassium balance. To investigate the renin-angiotensin system and the influence of sympathetic nervous system on the regulation of renin secretion, the renovascular hypertension was induced in the dogs by constriction of unilateral renal artery, and the plasma renin activity was measured. The sodium load at the sites of macula densa was attained by furosemide, and then the activity of sympathetic nervous system was depressed by reserpine. The plasma renin activity was assayed by the method of Helmer and Cohn. By this bio-assay method, the plasma renin activity equivalent to 1 nanogram angiotensin-II can be measurable and the prepared plasma was found to have still vasopressor activity. The results observed in this experimental work are summarized as follows. 1. The blood pressure reached maximum on the 3rd postoperative day, and declined gradually to the level of preoperative day on the day of from the 6th to 12th day following constriction of renal artery. 3. The plasma renin activity was found to be well correlated with the increase of blood pressure, and then declined to its preoperative level with the reduction of blood pressure. It appears, therefore, that the renin-angiotensin system plays an important role in the pathogenesis of renovascular hypertension. 4. The urine flow rate in normal and reserpinized dogs was the same before administration of furosemide, but its rate was significantly increased in both groups after furosemide. The urine flow rate of reserpinized dogs, however, was significantly lower than that of the normal dogs during the first 5 minutes. 5. The urinary sodium excretion in normal and reserpinized dogs was significantly increased in both groups after administration of furosemide and there were no difference between the two groups. 6. The plasma renin activity of renal venous blood was significantly higher than that of femoral arterial blood in both groups before and after administration of furosemide. 7. The plasma renin activity of reserpinized dogs was significantly lower than that of normal dogs before administration of furosemide. After furosemide, however, the plasma renin activity was significantly increased in 30 minutes in both groups. This increase of plasma renin activity was less prominent in resepinized dogs than in normal. This results would suggest that the intrarenal mechanism regulating renin secretion also requires an intact sympathetic nervous system.
Animals ; Blood Pressure ; Constriction ; Dogs ; Furosemide ; Hypertension ; Hypertension, Renovascular ; Ischemia ; Kidney ; Perfusion ; Plasma ; Potassium ; Renal Artery ; Renin* ; Renin-Angiotensin System ; Reserpine ; Sodium ; Sympathetic Nervous System

No abstract available.
HLA-D Antigens* ; Humans*

No abstract available.
Eating*

No abstract available.
Nutrition Policy*

No abstract available.
Aerospace Medicine* ; Aviation* ; Hungary*

PURPOSE: This study is used to investigate the correlation among a stroke patient family's health, burden and quality of life. METHOD: Data was collected from one hundred twenty family care-givers registered at K and H Hospital in Seoul. Questionnaire data was drawn up by personal interviews aided by the staff nurses. The analyses of collected data are based on the rate of 100 percentage to the average, t-test, ANOVA, DMR, Pearson Correlation. Result: (1) The influential factors on physical health proved to be age, sex, academic career, matrimonial status, present occupation, economic situation, the relationship with the patient, the patient-caring term, and the family-formation. The psychological health issues were age, final academic career, matrimonial status, the relation with patient and the family-formation. Burdens were shown to be age, matrimonial status, the relation with patient, and the patient-caring term. The quality of life was determined by age, final academic career, matrimonial status, and the relationship with the patient, the patient- caring term, and the family-formation. (2) The rate of the physical condition was 2.87, the psychological condition 2.43, the sense of burden 3.08, and the quality of life was 2.42. (3) The rate of correlation between the burden and the quality of life was (r= -.547), the psychological health and the burden was (r= -.531), the physical health and the burden was (r= -.263), physical health and quality of life was (r= .301), psychological health, and quality of life was (r= .413). CONCLUSION: It follows from this study that there is a very close correlation among the stroke patient family's health, the burden, and quality of life. Therefore it is necessary that we should find various nursing intervention ways in order to mitigate the burden of family when caring for the stroke patients.
Humans ; Nursing ; Occupations ; Quality of Life ; Surveys and Questionnaires ; Seoul ; Stroke*

BACKGROUNDS: Postural instability and vertigo arc not uncommon complaint from Parkinson`s disease (PD) patients. But little is known about the underlying cause of the symptoms. METHODS: Thirty-two patients with over 55 year of age, having Parkinson`s disease are studied with using a recently developed computerized dynamic posturography(CDP) and rotating chair testing(ROT) RESULTS: Vestibular dysfunction pat tent is found in 21 patients and improper use of vision was found in 10 patients. Delayed motor latency was noted in 5 patients. Saccadie dysmetria and prolonged saccadic reaction times were common features in all patients. 6 patients(18.8%) had absent responses in cold( 17degrees C) water caloric resting bilaterally and decreased responses in the lower frequencies(0.01~0.16 Hz) by ROT. Their vestibulo-ocular reflex could be suppressed during the ROT with visual fixation. MRI showed the presence of an infarction of the caudal cerebellum in one patient, the pons in another, and narrowed vertebral arteries in two patients. CONCLUSION: Relatively high incidence of vestibular dysfunction is associated with postural instability and increasing severity of symptoms. The main site of dysfunction in postural control is likely to be at a central motor level.
Cerebellar Ataxia ; Cerebellum ; Humans ; Incidence ; Infarction ; Magnetic Resonance Imaging ; Parkinson Disease* ; Pons ; Reaction Time ; Reflex, Vestibulo-Ocular ; Vertebral Artery ; Vertigo ; Water

BACKGROUND: It is well known that many patients with vertigo become vertinous when all alteration o the body position occurs while either head-shaking or after standing up. Posturaphy conducted with those patients when standing still is thus not always successful in detecting abnormal symptoms However. such abnormalities can be easily detected when the patients are subjected to motion-stress, such as head -shaking or alterations of the body position. The effect of such motion-stress on the disturbance of the centroid in normal individuals has yet to he clarified. METHODS: In this study, posturography was conducted normal subjects who were subjected to motion-stress in the manner mentioned above and the results of this test were then compared with the findings of a conventional test. RESULTS: Through this comparison no increase in the unbalance, as a result of the applied motion-stress, was observed for the X distance(XD), Y distance(YD) and Length(LNG). However, a significant increase in the imbalance was found for the XD and LNG itt (lid subjects. CONCLUSION: Therefore, motion-stress, such its head-shaking or alterations of the body position can be helpful in detecting vertiginous symptoms in vertigo patients. But in the elderly patients the merit of above stimuli during the test should be vet clarified
Aged ; Head ; Humans ; Vertigo