No abstract available.
Thromboangiitis Obliterans*

No abstract available.
Autografts*

PURPOSE: To describe the MR findings of simple bone cyst. MATERIALS AND METHODS: We analyzed the signal intensity of the cystic contents, their margins, and internal septae, and the presence of bony fragment and pathologic fracture, and enhancement patterns in MRI of 10 pathologically confirmed simple bone cysts. RESULTS: On MR imaging, the cystic contents were of homogeneously low signal intensity on T1WI and high signal intensity on T2WI in nine cases and fluid-fluid level was seen in one case. The cystic margins were dark in all sequences. There were not any fragment in the cysts. Among the four cases with pathologic fracture, one case had fluid-fluid level and two had some areas of enhancement in the cyst or adjacent soft tissue. All nine cases with gadolinium enhancement showed thin rim enhancement along the inner margin of the cysts and internal septae. CONCLUSION: Homogeneous fluid-like signal intensity of cystic content and thin rim enhancement of margin and internal septae in MR imaging are believed to be helpful in the diagnosis of simple bone cyst.
Bone Cysts* ; Diagnosis ; Fractures, Spontaneous ; Gadolinium ; Magnetic Resonance Imaging

OBJECTIVES: Angiogenesis is a critical factor in the growth, progression, and metastatic spread of solid tumors. Angiogenic factors are soluble molecules released by the tumor itself and are able to induce an angiogenic response. Vascular endothelial growth factor(VEGF) is a multifunctional cytokine that has been shown to be an important regulator of tumor angiogenesis. The aim of this study was to determine the value of serum VEGF levels in the diagnosis of ovarian cancer and in the differential diagnosis of adnexal masses. And we questioned whether the serum VEGF levels are related to cancer stages and prognosis of patients. METHODS: Serum samples were taken from 85 patients; healthy women(n=15), the patients with benign ovarian cyst(n=36), and the patients with ovarian cancer(n=34). The concentration of VEGF, CA-125, and CA 19-9 were determined in the serum of each patients before and after treatment with an enzyme linked immunoassay(EIA), RESULTS: There are statistical differences among the serum VEGF levels in patients with ovarian cancer(491.5+/-335.6 pg/ml), and benign ovarian cyst (247.7+/-183.6 pg/ml)(p<0.05). The patients undergoing cancer therapy had lower values than those without cancer therapy(p<0.05). The serum VEGF levels were not correlated with the cancer stages and histologic types(p>0.05) CONCLUSION: The serum VEGF level appears to be a helpful tool in the differential diagnosis of ovarian cancer and may help in predicting the therapeutic effects of patients with ovarian cancer.
Angiogenesis Inducing Agents ; Diagnosis ; Diagnosis, Differential ; Female ; Humans ; Ovarian Cysts ; Ovarian Neoplasms* ; Prognosis ; Vascular Endothelial Growth Factor A*

No abstract available.
Child* ; Humans

Osteoporosis, a disease characterized by low bone mass and microarchitectural deterioration of bone tissue leading to enhanced bone fragility and fracture risk, is a major public health problem. The diagnostic methods for osteoporosis include simple radiography, bone scan, DXA (Dual energy X-ray Absortiometry) and biochemical markers of bone turnover. Optimal treatment and prevention of osteoporosis require modification of risk factors, particularly smoking cessation, adequate physical activity, and attention to diet, in addition to pharmacologic intervention. The estrogens and raloxifene both prevent bone loss in postmenopausal women, and the estrogens probably also decrease the risk of first fracture. There is good evidence that raloxifene prevents further fractures in postmenopausal women who already have had fractures and some evidence that estrogen does as well. Bisphosphonate prevents bone loss and reduces fractures in healthy and osteoporotic postmenopausal women and in osteoporotic men as well. Risedronate is more potent and has fewer side effects than alendronate and reduces the incidence of fractures in osteoporotic women. Calcitonin increases bone mineral density in early postmenopausal women and men with idiopathic osteoporosis, and also reduces the risk of new fractures in osteoporotic women. All of the agents discussed above prevent bone resorption, whereas teriparatide and strontium increase bone formation and are effective in the treatment of osteoporotic women and men. New avenues for targeting osteoporosis will emerge as our knowledge of the regulatory mechanisms of bone remodeling increases, although issues of tissue specificity may remain to be addressed.
Absorptiometry, Photon ; Alendronate ; Biomarkers ; Bone and Bones ; Bone Density ; Bone Remodeling ; Bone Resorption ; Calcitonin ; Diet ; Estrogens ; Etidronic Acid ; Female ; Humans ; Incidence ; Male ; Motor Activity ; Organ Specificity ; Osteogenesis ; Osteoporosis ; Public Health ; Raloxifene Hydrochloride ; Risk Factors ; Smoking Cessation ; Strontium ; Teriparatide ; Risedronate Sodium

BACKGROUND: Epidermal cysts are the most common of all cysts. OBJECTIVE: The purpose of this paper is to report the clinical and histopathologic features of epidermal cysts. METHODS: We reviewed the clinical and histopathologic features of 205 cases that were diagnosed with epidermal cysts at the department of dermatology in Anam Hospital of Korea University for 11 years, from January 1983 to December 1993. RESULTS: 1. Of the 3,400 cases of skin biopsy specimens, 205 cases were epidermal cysts(6%). There were 141 male cases (68.8%) and 64 female cases (32.2%). The ratio of male to female was 1:0.45. 2. Most patients with epidermal cysts belonged to age ranging from 20 to 59 with the highest incidence in the 3rd decade. 3. The site of predilection of the epidermal cysts were face 94(45.9%), trunk 37(18.0%), neck 23(11.2%), leg 21(10.2%), arm 19(9.3%),scalp 7(3.4%), scrotum 2(1.0%), and vagina 2(1.0%). 4. Histopathologically, 61 cases (29.3%) were ruptured. The most common cystic wall change was acanthosis followed by atrophy, hyperplasia, hypergranulosis, parakeratotis, basalioma-like change, squamous eddies, dyskeratosis. The most common cystic content was keratinous material followed by parakeratotic cells, pigment, bacterial colony, RBC, inflammatory cells, hair shaft, calcification, trichilemmal keratinization, pilomatricoma-like change. The most common stromal change was giant cells followed by fibrosis, granulation tissue formation,vessel proliferation, pigment. CONCLUSION: According to our results, which agree with those of Chung, the epidermal cysts occur as a disease particular to young men, especially on the face. Histopathologically, when an epidermal cyst ruptures and the contents of the cyst are released into the dermis, a considerable foreign body reaction with numerous multinucleated giant cells results.
Arm ; Atrophy ; Biopsy ; Dermatology ; Dermis ; Epidermal Cyst* ; Female ; Fibrosis ; Foreign-Body Reaction ; Giant Cells ; Granulation Tissue ; Hair ; Humans ; Hyperplasia ; Incidence ; Korea ; Leg ; Male ; Neck ; Rupture ; Scrotum ; Skin ; Vagina

No abstract available.
Thyroid Gland* ; Thyroid Neoplasms*

No abstract available.

Rapid and accurate management is necessary for the emergency patients, but there is a few comprehensive and analyzed references about them and still the definition and the criteria of the urologic emergency are not defined. So a clinical observation was made on 382 patients, admitted to the Department of Urology through the emergency room of the Severance hospital during 5 years from January, 1972 to December, 1976. They were observed as following orders; annual, age, sex, symptoms, emergency managements, diagnostic procedures, diagnoses, associated diseases, and mortality rate etc. The results are as follows: 1. Urologic emergency patients were 382 (male 265, female 117). They were 1.4 % of the patients admitted through the emergency room, and 19.3% of the in-patients of the Department of Urology. 2. Symptoms and signs of the urologic emergency were pain (209 cases), gross hematuria (48 cases), acute retention (42 cases), acute genitourinary infection (38 cases), genitourinary injury (66 cases), shock (13 cases), and uremia(24 cases). 3. I.V.P. was the most common diagnostic procedure, but bone X-ray and the cystourethrogram were more common in genitourinary injury. 4. Emergency managements were performed in 227 cases. Pain control was most common (52t), then indwelling of the Foley catheter and transfusion were next. 5. In pain, flank or abdominal pain was most common (191 cases) and the most common cause. was lower 1/3 ureteral stone. 6. The causes of the gross hematuria were genitourinary tumor (11 cases), calculi(10 cases), acute cystitis(9 cases), and acute pyelonephritis (7 cases). 7. Acute retentions were commonly developed in old aged men and the most common cause was B.P.H. (42. 9%), then urethral stricture (23. 8%). 8. Acute genitourinary infections were most common in 3rd decade women. 9. Genitourinary injuries were most commonly occurred in the spring (34. 8%). The most common cause was kick or blow (43.9%) and the most common organ was urethra (40%). The most common combined injury was pelvic bone fracture (36. 8%). 10. The causes of the shock were genitourinary injury(84.6%) and bladder tumor (15. 4%). 11. The most common cause of uremia was genitourinary tumor (25%), then ureteral stricture (20. 8%). 12. In 30 cases, the presumptive diagnoses were different from the definite diagnoses. 43.3% of them were suspected as urinary calculi, but confirmed as acute pyelonephritis, ureteral stricture and tumor etc. 13. Associated diseases were common in old aged patients and cardiovascular (33%) or respiratory diseases (28.4%) were common. 14. Conservative treatment was most commonly performed, but suprapubic transvesical prostatectomy was more common in acute retention. 15. 7 patients were died and the mortality rate was 1.8%.
Abdominal Pain ; Catheters ; Constriction, Pathologic ; Diagnosis ; Emergencies* ; Emergency Service, Hospital ; Female ; Flank Pain ; Hematuria ; Humans ; Male ; Mortality ; Pelvic Bones ; Prostatectomy ; Pyelonephritis ; Shock ; Uremia ; Ureter ; Urethra ; Urethral Stricture ; Urinary Bladder Neoplasms ; Urinary Calculi ; Urology