1.Pharmacotherapy and Surgical Therapy in the Obese Children and Adolescents.
Journal of the Korean Academy of Family Medicine 2004;25(8):579-584
No abstract available.
Adolescent*
;
Child*
;
Drug Therapy*
;
Humans
4.Quantitation of T Lymphocytes and T Subsets Peripheral Blood and Cutaneous Lesion in Patients with Atopic Dermatitis.
Korean Journal of Dermatology 1987;25(3):309-317
This study was undertaken to elucidate any quantitative abnormalities of T cells and T subsets(helper/inducer T cell: T cell and suppressor/cytotoxic. T cell; Tsc cell) in the peripheral blood and cutaneous lesion in patients with atopic dermatitis by using monoclonal antibodies, and to ascertain whether there are any relations bctwcen such immunologic abnormalities and the severity of the disease. Thirty seven patints(19 male, 18 female) were entered in this study, who vistited the Departement of Dermatology of Seoul National University Hospital frnrn February 1985 to November 1985. The control group comprised fifteen healthy children (8 male, 7 female). The peripheral blood samples of 30 patients and the skin biopsy specirnens of 29 patients were examinecl. Both were examined in 22 patients. The results showed that there was a quantitative abnormality in pcripheral blood Tsc cells in patients with atopic dermatitis and it could be related to the severity of the disease. The predominance of T cells seemed to be relatecl to the pathogenesis of atopic dematitis.
Antibodies, Monoclonal
;
Biopsy
;
Child
;
Dermatitis, Atopic*
;
Dermatology
;
Humans
;
Male
;
Seoul
;
Skin
;
T-Lymphocytes*
5.An Experimental Study on the Passive Transfer of Dermpgaphism.
Korean Journal of Dermatology 1981;19(1):55-58
Dermographism is an exaggerated triple response of Lewis and appears as a lineat wheal with a flare at a site in which skin is briskIy stroked with a firm object. The etiology and pathogenesis of dermographism are uncertain but passive transfer tests are sometimes poeitive. The active serum factor has been characteiized as Ig E in some patients. In this experimental study, we tried passive transfer of dermographism with the sera of the patients with dermographism. Twelve dermographic patients' sera were tested to fourteen normal healthy persons and two asymptomatic dermographic persons, total number of thirty nine cases. Only two recipients were passively transferred but they showed positive responses to all sera tested, two and three respectively. This result suggests that not only serum factor but also recipient's factor(s) may be concerned in passive transfer of dermographism.
Humans
;
Intradermal Tests
;
Skin
;
Stroke
6.Argon Laser Therapy of Nevus Flammeus.
Korean Journal of Dermatology 1983;21(1):77-83
Nevus flammeus is benign but cosmetically devastating congenital vascular malformation whose past treatments have been marred by unacceptable complication or by unacceptable ineffectiveness. The argon laser is a therapeutic device which has been newly applied to this condition. Blue-green argon light is absorbed by the intraluminal red hemoglobin molecule, leading to the destruction of blood vessels. This study was undertaken to evaluate the therapeutic effect, to look for complications caused by the argon laser on nevus flammeus and to investigate the prognostic values of the color, the degree of blanching and the histological pattern of lesion after laser treatment. All patients were treated with Coherent Radiation Model No. 1,000 Laser with a spot size of 1mm diameter. The power range was 1.8W (irradiance of 229W/cm2), the pulse duration was 0.4 second and the repetition rate was 120 impulses per minute. The result was evaluated according to the criteria of Gilchrest(Table 1). Among the 109 patients who have been treated between November, 1981 and July, 1982 at the Department of Dermatology, Seoul National University Hospital, data from the 49 patients who could be followed up was evaluated and analyzed. (countinued..)
Argon*
;
Blood Vessels
;
Dermatology
;
Humans
;
Laser Therapy*
;
Nevus*
;
Port-Wine Stain*
;
Seoul
;
Vascular Malformations
7.Bicervical Bicornuate Uterus with Unilateral Cervical Atresia and Homolateral Renal Agenesis.
Jong Woo HONG ; Seon Kyung LEE
Korean Journal of Obstetrics and Gynecology 1999;42(12):2841-2846
Double uterus with unilateral hematometra and ipsilateral renal agenesis is a rare Mullerian duct malformation. This complex of anomalies is seen in adolescents and young women with progressive dysmenorrhea, abdominal pain, menstrual irregularities and a pelvic mass. Appropriate preoperative diagnosis and treatment will prevent unnecessary procedure and offer relief of symptoms. We report one case of bicornuated uterus with unilateral cervical atresia and homolateral renal agenesis with a brief review of concerned literatures.
Abdominal Pain
;
Adolescent
;
Diagnosis
;
Dysmenorrhea
;
Female
;
Hematometra
;
Humans
;
Unnecessary Procedures
;
Uterus*
8.The Joint Multicenter Study on the Atrial Fibrillation in Korea.
Seon Mee LEE ; Chung Whee CHOE
Korean Circulation Journal 2000;30(5):646-652
BACKGROUND: Atrial fibrillation (AF) is one of the most common clinical arrhythmia. AF may cause disabling symptoms and serious adverse effects, such as impairment of cardiac function or thromboembolic events. Until now, there were no study about the clinical characteristics of atrial fibrillation throughout this nations. The purpose of this study is a establishment of epidemiologic database of patients with atrial fibrillation in this nations. METHODS: 867 patients from 12 university hospitals were involved in this study. Atrial fibrillation were diagnosed with documented ECG in all patients. Medical history, physical findings, basic Laboratory finding, ECG, echocardiography and 24-hour Holter monitoring of these patients were evaluated. Chronic atrial fibrillation were defined as the duration of AF longer than 72 hours regardless of intervention. RESULTS: In patients with chronic atrial fibrillation, the most common symptom was dyspnea and the most common associated diseases were valvular heart disease, hypertension and ischemic heart disease. 2) In patients with paroxysmal atrial fibrillation, the most common symptoms were palpitation, dizziness and chest pain, and the most common associated diseases were hypertension, ischemic heart disease and valvular heart disease. 3) left atrial size, systolic and diastolic left ventricular size in patients with chronic atrial fibrillation were significantly increased as compared those in patients with paroxysmal atrial fibrillation (p<0.001). 4) cardiomegaly and pulmonary edema were more common in patients with chronic atrial fibrillation (p<0.0001). CONCLUSIONS: This study is first large multicenter study about atrial fibrillation in this nations. These data can be used as basic data for follow up and management of atrial fibrillation.
Arrhythmias, Cardiac
;
Atrial Fibrillation*
;
Cardiomegaly
;
Chest Pain
;
Dizziness
;
Dyspnea
;
Echocardiography
;
Electrocardiography
;
Electrocardiography, Ambulatory
;
Heart Valve Diseases
;
Hospitals, University
;
Humans
;
Hypertension
;
Joints*
;
Korea*
;
Myocardial Ischemia
;
Pulmonary Edema
9.A Case of Achondroplasia.
Han Young LEE ; Seon Ock KHANG ; Woo Gill LEE
Journal of the Korean Pediatric Society 1984;27(12):1234-1238
No abstract available.
Achondroplasia*
10.Analysis of prognostic factors associated with the treatment failures in stage IB and IIA carcinoma of the uterine cervix.
Seon Kyung LEE ; Jae Hyun LEE ; Jung Eun MOK
Korean Journal of Gynecologic Oncology and Colposcopy 1993;4(1):76-88
One hundred fifty-seven patients wha underwent radical hysterectomy and pelvic lymphadenectomy for FIGO stage IB and IIA carcinoma of the cervix between February l975 and May 1987 were retros-pectively analysed to identify specific risk factors associsted with treatment failures. Prognostic factors inciuded clinical stage, histologic cell type, degree of differentiation, size of primary tumor, depth of stromal invasian, lymph-vaseular space invasion, and lymph node metastasis. Treatment results were evaluated according to the recurrence rate and 2-year absolute recurrence-free survival(NED) rate by the prognostie faetors and treatment modalities. Patients with lymph node me tases had a significantly higher incidence of bulky primary(-> 4cm), depth of stromal invasion(> 60% thickness), and lymph-vascular invasion(P<0.005). There was significant difference in the recurrence rate and 2-year, NED rate between cervical carcinoma stage IB and I1A(P <0.005). The pat,ients who had bulky primary tum~or(>4cm) and/or depth of stromal invasion (>60% thickness) had a higher recurrence and lower 2-year NKD rate(P<0.025, P<0.005), Unfortunately, it was not possible to demonstrate that these detrimentel effects could be overeorne by postoperetive radiation. When adjoined for these risk group, traditionally reported poor prognostic factors such as nodal metatasis, cell type and differentiation, lyrnphi-vascular mvasion assume less importance in our studies. In this study, prognosis is most inf1ueneed by clinical stage, depth of stromal invasion, and size of primary tumor,
Cervix Uteri*
;
Female
;
Humans
;
Hysterectomy
;
Incidence
;
Lymph Node Excision
;
Lymph Nodes
;
Neoplasm Metastasis
;
Prognosis
;
Recurrence
;
Risk Factors
;
Treatment Failure*