1.The Scope of HCV Vaccine Development.
The Korean Journal of Hepatology 1997;3(2):108-113
No abstract available.
4.Comparative Study of Pre-operative MRI Diagnosis of Lumbar Herniated Intervertebral Disc and Post-operative Findings.
Young Kyu KIM ; Sung Ho KIM ; Young Sung KIM
Journal of Korean Society of Spine Surgery 1997;4(1):157-164
No abstract available.
Diagnosis*
;
Intervertebral Disc*
;
Magnetic Resonance Imaging*
5.A Clinical Study of Meniscal Lesions
The Journal of the Korean Orthopaedic Association 1981;16(3):546-551
We meniscectomized 27 knees with meniscal lesions for disabling symptoms after the diagnosis by clinical evaluation and arthrography from January, 1970 to May,1979. Statistical analyses were as follows: 1. Male was affected 2 times more than female. The most meniscal lesions occurred in the age group between 10 and 29 years old (67%). 2. The lateral menisci were affected 2 times than the medial. In the former, the middle segments were affected most frequently and in the latter, the posterior horns. 3. The general diagnosis of torn meniscus for the 27 knees was correct by clinical evaluation for 19(71%), by arthrography for 20 (74%) and by two methods for 24 (88%). 4. In the follow-up study, satisfactory results were obtained in. 79%.
Animals
;
Arthrography
;
Clinical Study
;
Diagnosis
;
Female
;
Follow-Up Studies
;
Horns
;
Humans
;
Knee
;
Male
;
Menisci, Tibial
6.The Study on the Control of Renin Secretion.
Korean Circulation Journal 1972;2(1):1-19
It is still not well documented what the basic roles for the regulation of renin secretion from the kidney take place. Since the early study on the renal ischemia for the production of hypertension was introduced, the renin-angiotensin system has been regarded as the possible pathogenetic mechanism for the renovascular hypertension. The renin-angiotensin system, however, could be activated by various stimuli, such as, the changes of intrarenal perfusion pressure, the load or concentriation of sodium at the sites of macular densa, the changes of the sympathetic nervous activity and the changes of potassium balance. To investigate the renin-angiotensin system and the influence of sympathetic nervous system on the regulation of renin secretion, the renovascular hypertension was induced in the dogs by constriction of unilateral renal artery, and the plasma renin activity was measured. The sodium load at the sites of macula densa was attained by furosemide, and then the activity of sympathetic nervous system was depressed by reserpine. The plasma renin activity was assayed by the method of Helmer and Cohn. By this bio-assay method, the plasma renin activity equivalent to 1 nanogram angiotensin-II can be measurable and the prepared plasma was found to have still vasopressor activity. The results observed in this experimental work are summarized as follows. 1. The blood pressure reached maximum on the 3rd postoperative day, and declined gradually to the level of preoperative day on the day of from the 6th to 12th day following constriction of renal artery. 3. The plasma renin activity was found to be well correlated with the increase of blood pressure, and then declined to its preoperative level with the reduction of blood pressure. It appears, therefore, that the renin-angiotensin system plays an important role in the pathogenesis of renovascular hypertension. 4. The urine flow rate in normal and reserpinized dogs was the same before administration of furosemide, but its rate was significantly increased in both groups after furosemide. The urine flow rate of reserpinized dogs, however, was significantly lower than that of the normal dogs during the first 5 minutes. 5. The urinary sodium excretion in normal and reserpinized dogs was significantly increased in both groups after administration of furosemide and there were no difference between the two groups. 6. The plasma renin activity of renal venous blood was significantly higher than that of femoral arterial blood in both groups before and after administration of furosemide. 7. The plasma renin activity of reserpinized dogs was significantly lower than that of normal dogs before administration of furosemide. After furosemide, however, the plasma renin activity was significantly increased in 30 minutes in both groups. This increase of plasma renin activity was less prominent in resepinized dogs than in normal. This results would suggest that the intrarenal mechanism regulating renin secretion also requires an intact sympathetic nervous system.
Animals
;
Blood Pressure
;
Constriction
;
Dogs
;
Furosemide
;
Hypertension
;
Hypertension, Renovascular
;
Ischemia
;
Kidney
;
Perfusion
;
Plasma
;
Potassium
;
Renal Artery
;
Renin*
;
Renin-Angiotensin System
;
Reserpine
;
Sodium
;
Sympathetic Nervous System
7.Platelet monoamine oxidase activity and its relationship to the positive and negative symptoms of schizophrenia.
Sung Hwan YOON ; Young Hoon KIM ; Sung Tae ZIN
Journal of Korean Neuropsychiatric Association 1991;30(1):38-46
No abstract available.
Blood Platelets*
;
Monoamine Oxidase*
;
Schizophrenia*
8.A new culture system for in situ observation of the growth and development of Eucyclops serrulatus (Copepoda: Cyclopoida) .
Sung Hee PARK ; Cheon Young CHANG ; Sung Shik SHIN
The Korean Journal of Parasitology 2005;43(4):141-147
A practical and convenient method of rearing Eucyclops serrulatus in a microculture environment is described. A complete life cycle of E. serrulatus was maintained in a narrow space on a microscope slide glass on which a cover glass of 22 x 40 mm in size was mounted at a height of 0.8 mm. The culture medium was constituted by bottled mineral water boiled with grains of Glycine max (soybean). Chilomonas paramecium, a free-living protozoan organism, was provided as live food. Growth of nauplii hatched from eggs to the first stage of copepodite took an average of 7.7 days, and the growth of copepodite 1 to the egg-bearing adult female took an average of 20.1 days in the microculture cell with an average life time of 44.7 days. Continuous passage of copepods was successfully maintained as long as sufficient medium and food were provided. The microculture method enables an in situ microscopic observation on the growth and developmental process of helminth larvae experimentally infected to copepods as well as of copepod itself. Furthermore, it does not require anesthetization and, therefore, minimize the amount of stress exposed to copepods during the handling process.
Protozoa
;
Male
;
Female
;
Culture Techniques/*methods
;
Culture Media
;
Copepoda/*growth & development
;
Animals
9.The celluar composition including lymphocyte subsets in colostrum and mature milk from mothers of preterm and full term infancy.
Young Hoon KIM ; Joon Sung LEE ; Sung Hoon CHO
Pediatric Allergy and Respiratory Disease 1993;3(2):20-31
No abstract available.
Colostrum*
;
Humans
;
Lymphocyte Subsets*
;
Lymphocytes*
;
Milk*
;
Mothers*
10.A study for the isolation of the causative organism,antimicrobial susceptibility tests and therapeutic aspects in patients with impetigo.
Sung Wook PARK ; Han Young WANG ; Ho Suk SUNG
Korean Journal of Dermatology 1993;31(3):312-319
BACKGROUND: It is traditiqnally considered that the non-bullous fonn of impetigo is primarily of streptococcal origin and the bullous form is of staphylococcal origin. However, recent reports have shown that Staphylococcus aureus (SA) has become the predominant cauative pathogen of non-bullous impetigo as well as of bullous impetigo. Objective. Our purpose was to evaluate the predominant causativi. pathogen, and to establish a therapeutic guideline for impetigo. METHOD: We described the characteristics of lesions and gerformed bacterial culture and susceptibility tests in patients with impetigo. Patients were treatecl by one of three frequently used antibiotics(erythromycin, cefuroxime, fusidic acid). RESULTS: Of 77 patients, there were 47 cases of crusted type(61.9%), 18 cases of mixed type with crusted and bullous lesiona(23.3%), 7 cases of mixed type with crusted and pustular lesions(9.1%) and 5 cases of bullous type(6.6%). SA was grown from 90.1% af the cases, in 83.1% of cases it was the only organism to be foind and no gowth of streptococcus was faund even in mixed infections. An antimicrobial susceptibility test of 63 strains of SA demonstrated high susceptibility to vancomycin(98.4%), cefuroxime(97.1%), oxacillin(96.4%), cephalothin(95.2%), fusidic acid(91.7%) etc, and high resistance to penicillin(93.7%), gentamicin(90.5%), tobramycin(88.9%) and erythromicin(80.9%). Of 19 patients treated with erythrornycin, 12(63.1% ) showed treatment failure at a weeks, while no treatment failure occured in groups treated with cefuroxime and usidic acid. There were statistically significant differences iri therapeutic effect between cefuroxirne and erythromycin(P=0.005 by two tailedy test), and betweer fusidic acid and erythromycin(P=0.0040. But there was no significant difference between cefuroxime and fusidic acid. CONCLUSION: The predominant pathogen of non-bullous impetigo a well as bullous impetigo was SA which were highly resistant to erythromycin and highly sensitive to efuroxime and fusidic acid. In the clinical response, cefuroxinie and fusidic acid treatment were most effective and erythromycin was inadequate for treatment of impetigo.
Cefuroxime
;
Coinfection
;
Erythromycin
;
Furosemide
;
Fusidic Acid
;
Humans
;
Impetigo*
;
Staphylococcus aureus
;
Streptococcus
;
Treatment Failure