BACKGROUND: Pemphigus foliaceus(PF) and pemphigus vulgaris(PV) have different target antigens which belong to the desmoglein(DG) subfamily of the desmosomal cadherins; DG in the case of PF and PV antigen(PVA) in the case of PV. OBJECTIVE: Because DG is also a normal major component of the intercellular adhesive core, we investigated the immunohistochemical distribution of DG in PF to compare and contrast the findings with those of PV. METHODS: Immunohistochemical analysis using streptavidin-biotin complex method with anti-DG monoclonal antibody was done in six cases of PF and six cases of PV, as well as two samples of normal skin as control. RESULTS: Both disorders showed abnormal intense diffuse cytoplasmic staining patterns in the lesional skin. Contrary to PF, showing complete loss of normal, rim-like, membranous staining, two of six cases of PV showed the relatively well preserved normal staining pat-terns in the upper epidermis. CONCLUSION: The differences in the expression of DG in the lesional skins between PF and PV suggest that PVA is distinct from DG, although an overlapping of antigens between PF and PV could exist.
Adhesives ; Cytoplasm ; Desmogleins* ; Desmosomal Cadherins ; Epidermis ; Methods ; Pemphigus* ; Skin

No abstract available.
Female ; Pregnancy ; Pregnancy in Adolescence*

No abstract available.
Urodynamics*

No abstract available.
Animals ; Humans ; Rats* ; Regeneration* ; Urinary Bladder*

In 1951, Leborgen pointed out the special diagnostic importance of punctate calcifications in the diagnosis of breast cancer by mammography. Calcifications within the breast may occure in both malignant and benign diseases, the characteristic findings have been reported subsequently by many other investigators. This study was done toreevalute the significance and diagnostic value of calcifications of female breast cancers. The clinical materals were 980 cases of those underwent mammography, and 76 cases of those histopathologically diagnosis was confirmed. Fine calcifications were radiologically found in 24 cases of these 76. A morphological analysis was made inregards to the relationship between the calcific particles and various mammary diseases. The results were asfollows; 1. The irregularly fine spiculate and punctate calcifications were found in 11 cases (45.8%) of cancergroup, and rather uniformly fine smooth calcifications were found in 14 out of 52 cases (26.9%) of benign conditions. 2. In cancer group, the calcifications were finely punctate or spiculate in shape and in numerable innumber with a tendency toward formation of densely packed clusters within and adjacent to the lesional areas. Nospiculate calcifications were observed in benign conditions. There were, however, no difference in either size ordensity of particles in both benign and malignant conditions. 3. These fine calcifications of the breast detectedby mammography seem to be a useful marker in localizing so small a lesion as not to be palpable and in obtaining proper biopsy specimen.
Biopsy ; Breast Neoplasms ; Breast ; Diagnosis ; Female ; Humans ; Mammography ; Research Personnel

In Korea, Kerion celsi caused by T. verrucosum was first reported by Kim et al in the Honam province in 1986. Since then three mare cases have been reported in the Young Nam province. Herein present a case of kerion celsi caused by T. verrucosum from Chungcheong province. The patient, a 7-year old female, showed a 4x 4cm sized, oval, yellow crusted and boggy patch with alopecia on the scalp. She was living on a farm in a rural area of Chungcheong province. Cows on the farm also exhibited similar skin lesions on the buttock. The same T. verrucosum was identified by a characteristic colony morphology on Sabourauds dextrose agar and chains of chlamydoconidia with mycologic stain from scales of lesions of patient and cows. This skin lesion was successfully treated with griseofulvin.
Agar ; Alopecia ; Buttocks ; Child ; Female ; Glucose ; Griseofulvin ; Humans ; Korea ; Scalp ; Skin ; Tinea Capitis* ; Weights and Measures

Lymphangiomas are uncommon tumors that are believed to result from abnormal communication between large dermal lymphatic channels and central lymphatic system. Predilection sites are the chest, neck, axilla, buttock and thigh but may occur on almost any area of skin. Retroperitoneum is very uncommon site of lymphangiomas. They show the highest incidence of onset in infancy, the majority are present by age 5 years. Three types are distinguishable: 1) superficial lymphangioma circumscriptum and 2) deep lymphangioma cavernosum and 3) cystic lymphangioma (hygroma). We report two cases of cavernosal type of lymphangiomas with asymptomatic abdominal mass in 4-year-old female and perineal mass in 2l-year-old male patient.
Axilla ; Buttocks ; Child, Preschool ; Female ; Humans ; Incidence ; Lymphangioma* ; Lymphangioma, Cystic ; Lymphatic System ; Male ; Neck ; Skin ; Thigh ; Thorax ; Urogenital System*

Fine needle aspiration biopsy cytology (FNA) for diagnosis of a variety of breast tum- ors has been proven to be a simple, safe, and cost saving diagnostic methodology with high accuracy. Cytologic specimens from 1,029 fine needle aspirations of the breast during last 3-year period were reviewed and subsequent biopsies from 107 breast lesions were reevaluated for cytohistological correlation. FNA had a sensitivity of 81.6% and a specificity of 98.3%. One out of 107 cases bio- psied revealed a false positive result (0.9%) and the case was due to misinterpretation of apocrine metaplastic cells in necrotic backgound as malignant cells. A false negative rate was 8.4% (9 of 107 cases biopsied). Six of 9 false negative cases were resulted from insufficient aspirates for diagnosis, and remaining three of 9 false negative cases revealed extensive necrosis with no or scanty viable cells on smears. The results indicate that for reducing false positive and false negative rates of FNA, an experienced cytopathologist and a proficient aspirator are of great importance.
Adenoma, Pleomorphic ; Aspirations (Psychology) ; Biopsy ; Biopsy, Fine-Needle ; Breast ; Carcinoma, Adenoid Cystic ; Carcinoma, Mucoepidermoid ; Child* ; Cost Savings ; Diagnosis ; Humans ; Necrosis ; Needles ; Sensitivity and Specificity ; Urinary Tract Infections* ; Urinary Tract* ; Vesico-Ureteral Reflux*

Trichomoniasis, a common and sometimes distressing condition in women, is caused by infection of the genitourinary tract by the pathogenic protozoan Trichomonris aginalis(T. vaginalis). Men may also be infected, although frequently without any symptoms, and most cases of trichomoniasis are sexually transmitted. The best evidence for an etiologic role for T. vaginalis is in nongonococcal urethritis(NGU). In epidemiologic studies, T,ginalis has been isolated from 1 to 68 percent in men with NGU. The nurnber of NGU is increasing rapidly than gonorrhea in deeloped nations, and in some developing countries, especially in Korea, In view of the difficulties in findng trichomonads by direct microsco by in men, urine culture and serodiagnosis plays an important role in the diagnostic work. Urine culture, indirect fluorescent antibody test(IFAT) and enzyme-linked immunosorbent assay (ELISA) were used to elecect T.vaginalis in 221 patients with male NGU. These patients visited the VD Clinic of ChoongKu Public Health Center in Seoul from May to August, 1989 and from March, 1990 to December, 1991. The results obtained were as follows.: 1. T. vaginalis was grown from only one of the 221 samples on TPS-1 meida. 2. In 208 NGU patients, there were 10(4.8%) positive reactions on IgG antibody in IFAT. 3. In 208 NGU patient, there were 14(6.7%) positive reactions to IgG antibody in ELISA. 4. No statistical significant correlation was found between then sults of IFAT and ELISA in individual patients. In conclusion, 1. Male trichomoniasis in patients with NGU was detected at a, significantly low rate. Due to the small number of patients in the test, further epidemiologic stidies of trichomoniasis in male NGU patient are necessary. 2. Serologic studies (IFAT and ELISA) have detected sorre trichomoniasis in male patients with NGU. These tests seem to be helpful in the diagnosis of male t-ichomoniasis.
Developing Countries ; Diagnosis* ; Enzyme-Linked Immunosorbent Assay ; Epidemiologic Studies ; Female ; Gonorrhea ; Humans ; Immunoglobulin G ; Korea ; Male* ; Public Health ; Seoul ; Serologic Tests* ; Urethritis*

Priciples of kont-tying have assumed a new and enhanced role in operative laparoscopy. The surgeon should be familiar with extracorporeal knot-tying techniques. For extracorporeal knot-tying, a knot pusher is used to properly secure the knot. But a knot pusher has some limitation for tightening of the knot. I developed an instrument which has a slit and hole.(slit for knot pushing and hole for knot tightening) for a secure knot. By using this instrument(Lee's knot presser) it is very easy and secure for knot-tying. The surgeon can confirm and control the knot tightening.
Laparoscopy