There have been published manuscripts which fully suggest that there may be a topographic variance of contact sensitivity in experimental animals such as guinea pigs, hamsters and mice, probably due to a large extent to the topographic difference of Langerhans cell population and to a little extent to impact on the induction site. This assay was done to establish the possibility of involvement of a certain topographic variance in contact sensitivity reaction. Three different anatomical sites were chosen for the induction in three groups of five guinea pigs: the conventional site of the nuchal region, and the sacral aod. ahdominal skin regions. For the elicitation, two different concentrations of DNCB were applied on three sites along both sides of the spine in the back. The contact sensitivity reaction elicited by DNCB in the group of the nuchal abdominal skin induction was definitely stronger at the site closer to the nuchal region than that found at sites closer to the sacral regior. but all animals of the group sensitized on the sacral region showed comparatively uniform reaction. Zvidently, contact sensitivity reaction is influenced mainly by topographic variance hut shows a litte difference depending upon induction sites.
Animals ; Cricetinae ; Dermatitis, Contact* ; Dinitrochlorobenzene ; Guinea Pigs* ; Guinea* ; Mice ; Sacrococcygeal Region ; Skin ; Spine

No Abstract Available.
Thyroid Diseases* ; Thyroid Gland*

No abstract available.
Primary Health Care* ; Smoke* ; Smoking*

No abstract available.
Anemia, Aplastic*

The survey was carried out on 1,031 primary school children for about 1 month, from June 1, to June 30, 1974, for the purpose of understanding indirectly socio-medical status of a remote rural area, reflecting health status of primary school children. The summarized results were as follows: 1)The average age of surveyed children according to school year by sex was older in girls than in boys. The entrance in school at suitable age was peaked as 80.9% in boy of 5th school year and 72.4% in girls of 3rd school year, and also sunk 68.8% in boy of 2nd school year and 58.7% in girls of 1st school year. 2) Prevalence rate according to W. H. O. diseases classification during last a month and a year. a) During last month: The diseases of respiratory system remarked the highest 101.1 in boys and 116.6 in girls. The next were diseases of digestive system (24.2 in boys and 32.1 in girls). The girls were higher than boys in prevalence rate. b) During last year: The diseases of digestive system ranked the highest 133.0 in boys and next, the diseases of respiratory system (108.6 in boys). c) Present illness: Number of code III ranked the highest 129.2 and next XII(127.3) in boys but inverted in girls such as XII(144.9) and III(116.7) and also, Number of code XVII was prevalence twice in boys than in girls. d) Chief complaints by sex: Abdominal pain ranked the highest 71.2 per 1,000 population and next headache (34.7) in boys but headache ranked the highest 88.5 and next abdominal pain (63.3) in girls. e) Water drinking habit: Number of code IX was higher in habit of raw water drinker than in habit of boiled water drinker and healthy children were higher in boiled water habit group than in raw water habit group. The diseases of respiratory system were the highest 124.74 in girls and next, the diseases of digestive system (52.3 in girls). According to school year, healthy children were increased to higher grades. 3) Average sick day per total surveyed children and patient during last months and last year. a) Per surveyed 1,031 children was 0.28 days during last month and 0.98 days during last year. And also per patient was 1.78 days during last month and 3.22 days during last year. b) Average sick day was higher in girls than in boys during last month, but inverted during last year. 4) Average absented day per total surveyed children and patient during last month and last year. a) Per survived 1,031 children was 0.43 days during last month and 3.81 days during last year. b)Per absented children were 2.0 days during lst month and 7.10days during last year. c)Per absented children were 8.16 days in boys and 3.17 days in girls. 5)Utilization of medical facilities: The drug store was consulted 91.2% of the total utilized boys and girls. The strengthening of medical facilities and medical care activities in health subcenter is urgently required. 6)Medical Expense by period and sex: a) Average medical expense per surveyed 1,031 children were 35.95 won, per patient were 298.04 won during last month. b) Average medical expenses per survey children (omitted 1st school year) were 80.56 won, per patient were 243.98 won and per treated patient were 318.87 won during last year. c) Medical expenses were higher in boys than in girls. 7) Rohrer index by sex, present illness and school year. a) Average Rohrer index was 129.8 in boys and 126.2 in girls. b)Average Rohrer index was increased for 1st school year to 2nd school year and thereafter falling down step by step by school year. c) Under 151-160 Rohrer index number of code III was the highest and above 151-160 Rohrer index of code was peaked.
Abdominal Pain ; Child* ; Classification ; Digestive System ; Drinking ; Female ; Headache ; Humans ; Male ; Prevalence ; Respiratory System ; Sick Leave ; Water

No abstract available.
Malaria*

Anti-rat lymphocyte rabbit serum was prepared with lymphoid tissue of rat spleen. Prednisolone, Imuran and this antiserum were used to prolong the survival of full-thickness sliin homograft in albino rats. The results were as follows. l. Administratio of tle anti-rat lymphocyte rabbit serum in a dose of 0. 3cc for 2 days before grafting and 0. 3cc every 3 days until rejection resulted in prolongation of the, urvival of the grafts. (Mean, 15.3 days) 2. Administration of preInisolone to the recipients in a dose of 2mg/kg/day from 7 days Iielore grafting to the time of rejection resulted in prolongation of survival of the, rafts. (Mean, 8.4 days) 3. Adminitration of Imuran to the reciipients in a dose of 5mg/kg/day from 7 day defore gvafting to the time cif rejection resulted in prolongation of the survival of ther afts. (Mean,14.6 days)
Allografts* ; Animals ; Azathioprine ; Immunosuppressive Agents* ; Lymphocytes ; Lymphoid Tissue ; Prednisolone ; Rats* ; Skin* ; Spleen ; Transplants

We report herein a rare and grotesque case of a 19-year-old male with faun tail on the lumbosacral area of the back, presented from birth. The lesion was a 10 × loan sized patch with the circumscribed tuft of coarse terminal hairs about 10 to 25 an in length downward like a horse-tail. In the center of the patch was a 4 × 3cm sized brown macule in which was a 2 × lan scar. The skin biopsy from the brown macule revealed mild hyperkeratosis with basilar hyperpigmentation. Lumbar radiography showed findings of spina bifida occulta affected from L-4 to total sacral segments. There was mild saddle-hypoesthesia in the neurologic study.
Biopsy ; Cicatrix ; Hair ; Humans ; Hyperpigmentation ; Local Area Networks ; Male ; Parturition ; Radiography ; Skin ; Spina Bifida Occulta ; Tail* ; Young Adult

We report herein a rare and grotesque case of a 19-year-old male with faun tail on the lumbosacral area of the back, presented from birth. The lesion was a 10 × loan sized patch with the circumscribed tuft of coarse terminal hairs about 10 to 25 an in length downward like a horse-tail. In the center of the patch was a 4 × 3cm sized brown macule in which was a 2 × lan scar. The skin biopsy from the brown macule revealed mild hyperkeratosis with basilar hyperpigmentation. Lumbar radiography showed findings of spina bifida occulta affected from L-4 to total sacral segments. There was mild saddle-hypoesthesia in the neurologic study.
Biopsy ; Cicatrix ; Hair ; Humans ; Hyperpigmentation ; Local Area Networks ; Male ; Parturition ; Radiography ; Skin ; Spina Bifida Occulta ; Tail* ; Young Adult

34,073 prospective transfusion candidates sera, among 127,087 hospitalized patients in Hanyang University Medical Center between Jan. 1989 and Dec. 1993, were analyzed for detection of red cell irregular antibodies screening and identification. This study revealed investigation of the distribution and the characteristics of irregular antibodies. Tube method was performed including saline room temperature, saline 37 and antiglobuline phase. The following results were obtained. 1. Of 127,087 inpatients, prospective blood transfusion candidates were 34,078, 26.8%. 2. 151 cases out of 34,078 sera was positive irregular antibody, 0.443 %. 3. Frequency of irregular antibodies were 15 cases(0.044 %) of anti-Lea, 14 cases(0.041%) of anti-Leb, 14 cases(0.041%) of anti-P1, 8 cases(0.0234%) of anti-IH and 8 cases(0.0234 %) of anti-E in order. 4. Undetectable cold antibody was 39 cases(0.1145%), warm antibody, 27 cases(0.0792 %). 5. It is required that various testing method for the safty transfusion.
Academic Medical Centers ; Antibodies* ; Blood Transfusion ; Humans ; Inpatients ; Mass Screening