Leiomyosarcoma of the breast is extremely rare. The natural history of leiomyosarcoma of the breast remains largely unknown because of the low incidence and lack of long-term follow up. But leiomyosarcoma of the breast appears to be less aggressive biologically than other sarcomas of the breast such as rhabdomyosarcoma. In an attempt to define diagnostic criteria of smooth muscle tumors of the breast, the reported cases of leiomyoma of the breast and nipple were also reviewed and compared with leiomyosarcomas by Chen et al(1981). Based on the result of this review, tumors with three or more mitoses per 10 HPF are leiomyosarcoma and those with no mitosis, necrosis, and significant atypia are leiomyomas. We have experienced a case of leiomyosarcoma of the breast. The patient was a 39 year-old female and was admitted due to a rapid growing right breast mass. The breast mass was noted 4 years ago and then this year the mass growed rapidly. Simple mastectomy was performed. Grossly the mass measured 11.0x8.0x8.0 cm in dimensions and was well circumscribed, pinkish, multinodular, and it was protruded from the cut surface. Microscopically the mass is composed of interlacing bundles of spindle shaped cells and multifocal large areas of hyalinized collagenous tissue. The individual spindle cells are slightly pleomorphic and occasionally show mitotic figures, 6~7 per 10 HPF in the most cellular area.
Female ; Humans ; Incidence

No abstract available.
Carcinoma, Hepatocellular*

No abstract available.
Osteochondritis Dissecans* ; Osteochondritis*

No abstract available.
Breast Diseases* ; Breast* ; Estrogens* ; Progesterone* ; Receptors, Estrogen* ; Receptors, Progesterone*

PURPOSE: To evaluate the surface anatomy of the central sulcus(CS), precentral gyrus(PrCG) and postcentral gyrus(PoCG) on the basis of sulci pattern on MR images. MATERIALS AND METHODS: The MR images were obtained in the plane 10 degree angled to the orbitomeatal line. The MR images of 120 subjects(6 months to 79 years) with normal anatomy were analyzed and another four subjects with known space occupying lesions were also reviewed. RESULTS: The identification of gyri was feasible on the axial T1WI from anterior to posterior and from upper to lower images. The STS demonstrated symmetric pattern on both sides in 84 of 120 cases (70%), including two cases of prominent STS pattern. The asymmetric pattern was seen in 36 of 120 cases (30%):14 of 120 cases (12%) on the right and 22 of 120 cases (18%) on the left at 4.5 cm above the level of the splenium of corpus callosum. The PrCG and PoCG and CS were identified well in all cases with the use 'of the sulci pattern. CONCLUSION: The identification of the gyri on the basis of the cerebral sulci pattern on MR images is useful and important when locating the space occupying lesion of the brain.
Brain ; Corpus Callosum ; Magnetic Resonance Imaging*

Five fetal maxillas were obtained from the autopsy file of fetal postmortem examination, and were examined by serial micro-sections of frontal plane and horizontal plane. Especially the area around the incisive canal of the maxilla was carefully observed. The results are as follows. 1) In 5 fetal maxillas extra-dental laminas and supernumerary tooth germs which are severely malformed in shape are found in the dilated incisive canal, where prominent vessels and nerves are distributed. 2) The supernumerary tooth germs disclose almost normal histo-differentiation of odontoblast and ameloblast, and there shows relatively abundant perifollicular fibrosis in the place of perifollicular bone. 3) It is observed that the over-growth of the extradental lamina from the dental ridge of deciduous central incisor frequently tends to direct toward the incisive canal that includes prominent vessels and nerves.

PURPOSE: We evaluated the distribution of hypoperfusion in patients with traumatic brain injury (TBI) and the relationship of thalamic hypoperfusion to severity of cognitive and behavioral sequelae. MATERIALS AND METHODS: Tc-99m ECD SPECT and MRI were performed in 103 patients (M/F=81/22, mean age 34.7+/-15.4 yrs) from 0.5 to 55 months (mean 10.3 months) after TBI. The patients were divided into three groups showing no abnormalities (G1), focal (G2) and diffuse injury (G3) on MRI. Psychometric tests assessed 11 cognitive or behavioral items. In all patients, we evaluated the distribution of hypoperfused areas in SPECT, and in 57/103 patients, neuropsychological (NP) abnormalities in patients with thalamic hypoperfusion were compared with those of patients without thalamic hypoperfusion. RESULTS: The perfusion deficits were most frequently located in the frontal lobe (G1, 42.3%: G2 34.5%: G3 33.3%), temporal lobe (24~26%) thalami (21~22.4%), parietal and occipital lobe (< or =10%). Numbers of NP abnormalities in the cases of cortical hypoperfusion with or without concomitant thalamic hypoperfusion were following: the former 4.7+/-1.5 and the latter 3.2+/-1.4 in G1, 5.0+/-1.1 and 4.8+/-1.2 in G2, 6.8+/-1.8 and 6.3+/-1.1 in G3, respectively. This difference according to thalamic hypoperfusion was significant in G1 (p=0.002), but was not significant in G2 or G3. CONCLUSION: SPECT in patients with TBI had demonstrated hypoperfusion mostly involving the frontal, temporal and thalami. In normal group on MRI, frontal hypoperfusion was more prominent than that of any other group, Furthermore in this group, SPECT could predict severity of NP outcome by concomitant thalamic hypoperfusion with cerebral cortical abnormalities.
Brain Injuries* ; Brain* ; Equidae* ; Frontal Lobe ; Humans ; Magnetic Resonance Imaging ; Occipital Lobe ; Perfusion ; Psychometrics ; Rabeprazole ; Temporal Lobe ; Tomography, Emission-Computed, Single-Photon*

No abstract available.
Hernia, Inguinal* ; Urinary Bladder*

No abstract available.
Adult ; Cholecystectomy ; Diagnosis, Differential ; Gallbladder Diseases/pathology ; Hemobilia/*diagnosis/pathology/ultrasonography ; Humans ; Male ; Tomography, X-Ray Computed

No abstract available.
Breast* ; Child* ; Humans