No Abstract Available.
Animals ; Apoptosis* ; Rats*

Psoriasis is common cutaneous disorder involving 0.1~3% Of the general population and is characterized by its marked chronicity and recurrence. A variety of factors, rarging from heredity, environment to abnormal cytodynamics and biochemical perturbation have been implicated but never proved as causative. In recent years, many studies on psoriasis have been reported, showing the presence of certain immunologic abnormalities in patients with psoriasis, and some authors postulated that these immunologic abnormalities, particularly in cell mediated immunity, may play a key role in the pathogenesis of psoriasis. This study was undertaken to evaluate cell mediated immune status of patients with paoriasis using several immunologic parameters. A total of 70 patients (35 were male and 35 were female) between the ages of l:l and 70 years entered this study at the Department of Dermatology of Seoul National University Hospital from January 1980 through September 1980. Peripheral blood T lymphocytes(early and total) were enumerated by E-rosette technique in 55 patients. Delayed cutaneous hypersensitivity reaction was measured in 3O patients using intradermal candidin, trichophytinand PPD. Active sensitization with DNCB was performed in 30 patients.
Dermatology ; Dinitrochlorobenzene ; Heredity ; Humans ; Hypersensitivity ; Immunity, Cellular ; Male ; Psoriasis* ; Recurrence ; Seoul

anserine folliculosis (Padilha-Gonqalves, 1977) is a skin disease occurring on the limited areas of the skin receiving prolonged friction and/or pressure by the other part(s) of the naked skin of the patient. Padilha-Goncalves named traumatic anserine folliculosis by stressing the etiologic factor, the pressure and friction, the goose skin appearance and the follicular nature of the basic skin lesions. A 7-year-old girl developed typical features of traumatic anserine folliculosis on the chin who had the habit of resting the chin on the right knee for 5 years while painting.

For parthenogenetic activation as a model system of nuclear transfer, microinjection and electroporation as activation treatments in bovine metaphase II oocytes were administered to each of three groups as follows: control group (treatments with Ca2+, Mg2+ -free PBS+100 micro M EGTA), IP3 group (control+25 micro M IP3) and IP3+ ryanodine group (control+25 micro M IP3+10 mM ryanodine). In experiments using microinjection, no significant differences were observed between any of the developmental stages of the electroporation experiment. For electroporation, cleavage rates were significantly higher in the IP3+ryanodine group than in the IP3 or control group (85.6% vs 73.7% or 67.6%, respectively). In the subsequent stages of embryonic development, such as morula and blastocyst formation, the IP3 and ryanodine group exhibited significantly higher rates of morula fomation than the IP3 or control groups (40.6% vs 24.2% or 16.7%, respectively). Similarly, the rate of blastocyst formation in the IP3+ryanodine group was significantly higher than the control group (16.3% vs 6.9%) but did not differ significantly from the IP3 group (16.3% vs 9.5%). In nuclear transfer, activation was performed at 30 hpm by microinjection and elecroporation with 25 micro M IP3+ 10 mM ryanodine followed by 6-DMAP treatment. No significant differences were observed at any stage of embryonic development and none of the embryos activated by electroporation reached either the morula or blastocyst stage. However, 3.8% and 1.9% of embryos activated by microinjection sucessfully developed to the morula and blastocyst stages, respectively. In conclusion, activation treatments using IP3 and ryanodine are able to support the development of bovine parthenogenetic and reconstructed embryos.
Adenine/administration & dosage/*analogs & derivatives/pharmacology ; Animals ; Cattle/*embryology/physiology ; Cell Fusion ; Electroporation/veterinary ; Embryonic and Fetal Development/*drug effects ; Enzyme Inhibitors/administration & dosage/pharmacology ; Female ; Inositol 1,4,5-Trisphosphate/administration & dosage/*pharmacology ; Microinjections/veterinary ; Nuclear Transfer Techniques ; Oocytes/drug effects/growth & development ; Parthenogenesis/*drug effects ; Protein Kinase Inhibitors ; Ryanodine/administration & dosage/*pharmacology ; Skin/cytology

No abstract available.
Humans ; Male* ; Thyroid Gland* ; Thyroid Nodule*

No abstract available.
Anxiety ; Cellular Phone ; Humans ; Impulsive Behavior

No abstract available.
Anxiety ; Cellular Phone ; Humans ; Impulsive Behavior

A case of intraneural ganglion of the peroneal nerve in an eleven year old boy is reported. The cystic ganglion, 5.5cm×2.0×1.0cm, which was located at the region of the bifurcation of the peroneal nerve without communication of any joint or bursa, was excised, The ganglion was recurred at 6 weeks after the first excision.
Ganglion Cysts ; Humans ; Joints ; Male ; Peroneal Nerve

As trochanteric fractures frequently occur in the elderly patients and complications such as pneumonia, thrombo-embolic disease, decubitus ulcer, and urinary tract infection are common, early mobilization after open reduction and internal fixation with hip nail are the standard treatment. Since 1931 when Smith-Peterson first introduced a tri-flanged nail, further more, since 1941 when Jewett pioneered the one-piece nail by adding a solid plate to a Smith-Peterson nail, numorous implants including threaded pins, screws, nails, and plates have been modified and desiged for fractured hips till now to achieve early ambulation and to maintain stable reduction. In 1955 Pugh and Ken introduced a sliding nail-plate and Schumpelick described the use of sliding screw-plate, which was modified further by Callender and Holt pioneered the concept of heavy nail in 1963. Recently compression sliding screw-plate is popular. Also many surgeons such as Evans, Dimon and Hughston, Sarmiento, and Boyd and Anderson have attempted to provide stable fixation of fracture by altering the position of fracture fragments to improve the mechanical resistances of bone to disruptive forces of weight-bearing. The surgical procedures of open reduction and internal fixation were carried out and followed for more than 6 months on 45 intertrochanteric fractures at Department of Orthopedic Surgery, Seoul National University Hospital, from Jan. 1968 to June. 1975 and the results were observed as follows. 1. Of 45 cases of inter-trochanteric fractures 28 cases occurred in man, 17 cases in woman and each mean age was 54 years in man, 74 years in woman. 2. Of fixation devices, Smith-Peterson nail-plates were used in 19 cases, Jewett nails in 15 cases, compression sliding screw-plates in 9 cases, Smith-Peterson nail in 1 case, and Ken sliding nail-plate in 1 case. 3. Stable fractures occurred in 10 cases were fixed internaly after anatomical reduction. 4. Dimon-Hughston reductions and Jewett Nailing were achieved in 11 cases of 12 unstabIe fractures and had disadvantages such as some limitation of R.O.M. of the affected hip, shortening, and valgus deformity. 5. Of 9 unstable fractures treated by compression sliding screw-plate 7 cases were reduced as anatomicaly as possible and 2 cases were reduced non-anatomicaly because of impossible anatomical reduction but good results were obtained except one failed nailing. 6. Of 7 failures, 6 cases resuIted from failures of nailing during operation and only 1 failure resulted in varus defermity after Dimen-Hughston reduction with Jewett nail.
Aged ; Congenital Abnormalities ; Early Ambulation ; Female ; Hip ; Hip Fractures ; Humans ; Orthopedics ; Pneumonia ; Pressure Ulcer ; Seoul ; Surgeons ; Urinary Tract Infections ; Weight-Bearing

Clinical observation of thirty-eight cases of pyogenic osteomyelitis of the spine for the period of eleven years, from 1965, at Seoul National University Hospital was carried out with the following results. 1. The incidence of pyogenic osteomyelitis of the spine among total cases of the pyogenic osteomyelitis was 6.9% and the ratio between the spine tuberculosis and the pyogenic osteomyelitis of the spine was 1:0.067. 2. The sex ratio between male and female wss 3.8: 1 The incidence was higher ia the second and third decade and the average prevalent age was 30.8 years of age. 3. The site of infection was in the lumbar vertebrae in 25 cases(66%), thoracic in seven(19%), lumbosacral in three, sacral in two and cervical in one. In the region of a vertebra, the vertebral body was affected in 33 cases (87%) and the neural arch and processes in other 5 cases (13%) 4. The causative micro-organism was isolated in 27 cases from the diseased focus; coagulase positive staphylococcus in 18 cases (67%), streptococcus in one, salmonella in one and the mixed infection in two. 5. Frequent clinical symptoms and signs were back pain, tenderness, muscle spasm, fever and chillness, and limited motion of the spine. 6. The roetgenographic findings were in order of disc space narrowing, destruction of the vertebral body, kyphosis or loss of lordosis, erosion, bony bridging or spur formation, sclerosis and paravertebral abscess. 7. The conservative treatment was performed in 14 cases. Among 7 cases in which the follow-up was possible, only 3 cases obtained the satisfactory result, four cases were readmitted for the recurrence and two cases among them needed the operative treatment later. The operative treatment was peformed in 26 cases; The focal curettage with anterior interbody fusion through anterior approach was carried out in 13 cases with the satisfactory result in almost all cases. 8. The advantages of the operative treatment were that the isolation of the offending organism was efficient and the definite diagnosis was feasible, and especially in cases of anterior spinal fusion the healing and union of the infected spine was better clinically and roetgenographically in comparision with those of conservative treatment, in which the expected spontaneous fusion was not found in any case and the recurrence was also frequent.
Abscess ; Animals ; Back Pain ; Coagulase ; Coinfection ; Curettage ; Diagnosis ; Female ; Fever ; Follow-Up Studies ; Humans ; Incidence ; Kyphosis ; Lordosis ; Lumbar Vertebrae ; Male ; Myalgia ; Osteomyelitis ; Recurrence ; Salmonella ; Sclerosis ; Seoul ; Sex Ratio ; Spasm ; Spinal Fusion ; Spine ; Staphylococcus ; Streptococcus ; Tuberculosis