1.A Case of Pityriasis Rotunda Associated with Adenocarcinoma of Pancreas.
Yean Sub JANG ; Seok Ho KIM ; Eil Soo LEE
Korean Journal of Dermatology 1987;25(6):782-785
We report a case of pityriasis rotunda occurring in a patient with pancreatic adenocarcinoma. The patient was a 64-year old female who had a pancreatic adenocarcinoma. The skin lesions were asymptomatic, multiple, various sized (1 to 15cm in diameter), isolated or confluent and finely scaly light brownish to grayish colored patches on the lower abdomen, back and thigh. Histopathologic findings shawed mild hyperkeratosis, atrophy, loss of granular layer, increased melanin pigments in basal layer of the epidermis and mild perivascular monocytic infiltration in the upper dermis.
Abdomen
;
Adenocarcinoma*
;
Atrophy
;
Dermis
;
Epidermis
;
Female
;
Humans
;
Melanins
;
Middle Aged
;
Pancreas*
;
Pityriasis*
;
Skin
;
Thigh
2.A Clinical Study and the Histamine Test in Patients with Herpes Zoster.
Yean Sub JANG ; Jong Min KIM ; Eil Soo LEE
Korean Journal of Dermatology 1988;26(6):846-853
We studied 283 patients with herpes zoster who visited to the Hangang Sacred Heart Hospital between January, 1982 and December, 1985 about the distribution of age, sex, seasonal incidence, associated diseases, camplications and the effect of systemic prednisolone on post herpetic neuralgia. And we also examined the functional states of involved sensory nerve endings by observing the axon flare response to histamine test. The results were as follows . 1. There was no significant differences in sexual and seasonal distributions. 2. There were low incidences of herpes zoster in age groups of below 20 years and over 70 years than age groups of 20 69 years. 3. Sites of involvement were thoracic(170 cases), cervical(38 cases), trigeminal(35 cases), lumbar(28 cases), sacral(11 cases) and facial(1 case) dermatomes. 4. Associated diseases were diabetes mellitus(7 cases), hypertension(7 cases). pulmonary tuberculosis(6 cases), malignant neoplasms(3 cases) and renal transplantation (1 case). 5. Complications were post herpetic neuralgia(18 cases), keratoconjunctivitis(9 cases), meningoencephalitis(1 case), Ramsay Hunt syndrome(1 case), urinary difficulty(1 case) and generalized varicelliform eruption(1 case). 6. The incidence of post-herpetic neuralgia was reduced by systemic prednisolone therapy in patients over 60 years. 7. There was no decrease of axon flare by histamine test on the affected area in 18 patients with herpes zoster.
Axons
;
Heart
;
Herpes Zoster*
;
Histamine*
;
Humans
;
Incidence
;
Kidney Transplantation
;
Neuralgia
;
Prednisolone
;
Seasons
;
Sensory Receptor Cells
3.US Characterization of Soft Tissue Hemangiomas of Extremities: Correlation with MR Signal Intensity.
Kyung Sub SHINN ; Sung Su HWANG ; Mi Sook SUNG ; Hye Suk JANG ; Jung Ik YIM
Journal of the Korean Radiological Society 1995;33(1):131-138
PURPOSE: To evaluate the US findings of soft tissue hemangiomas in extremities and to correlate the echo-pattern with MR signal characteristics of hemangiomas. MATERIALS AND METHODS: We retrospectively studied forty-two patients either with pathologically proven cases or with characteristic features of hemangiomas on MRI, US and plain film. Hemangiomas were divided into two types according to the locations;subcutaneous and intramuscular. Analytic points on US and MR findings were gross morphology of the mass, internal echo-pattern or signal characteristics. We correlated the echo-pattern with MR signal characteristics in hemangiomas. RESULTS: Subcutaneous hemangiomas revealed homogeneously anechoic mass on US, which were well correlated with MR signal characteristics' homogeneous low singnal intensity(SI) on Tl-weighted image(WI) and high SI on T2-WI. Intramuscular hemangiomas showed heterogeneously mixed echoic masses on US. An anechoic component on US corresponded to dilated vascular channels on MRI. The signal intensity of intramuscular hemangioma was less than that of subcutaneous fat on T1-WI and greater than that of fat on T2-WI. Both types of hemangiomas had tubular or lace-like appearance with interspersed fibrofatty septa. CONCLUSION: The echo-patterns in US were well associated with MR signal characteristics on MRI. Regarding US and MR features, intramuscular hemangiomas were different to subcutaneous hemangiomas.
Extremities*
;
Hemangioma*
;
Humans
;
Magnetic Resonance Imaging
;
Retrospective Studies
;
Subcutaneous Fat
4.Immunomodulators Extracted from Korean - style Fermented Soybean Paste and Their Function . 1 . Isolation of B Cell Mitogen from Korean - style Fermented Soybean Paste.
Bong Ki LEE ; Yun Soo JANG ; Sook Yi YI ; Kun Sub CHUNG ; Shin Yang CHOI
Korean Journal of Immunology 1997;19(4):559-570
Responses of mouse lymphocytes to the soybean paste fermented by Korean traditional fashion was examined to clarify its effects in cytokine production in vitro. A fraction of the soybean paste (KFSP-100) was prepared by precipitation with ammonium sulfate and by filtration through ultrafiltration membrane. KFSP-100 were added into cultures of fresh mouse splenic cells in vitro. KFSP-100 significantly enhanced the amount of IL-6 and TNF-a produced by macrophages and IL-6 and IFN-r produced by lymphocytes. Production of IL-12 by macrophages was not much affected by KFSP-100 treatments. The most noticeable finding was the fact that lymphocytes treated with KFSP-100 proliferated to an exceeding numbers (more than 10 times to the control) in 72 hours. The KFSP-100-induced proliferative response was specific to B cells since almost all of the KFSP-100-induced cells in the cultures of splenic cells were B cells. Furthermore, such a proliferative responses were equally observed only in cultures of purified B cells but not in cultures of T cells. In thermostability test, the biologically active components of the KFSP-100 is assumed to be either linear protein or glycoprotein. KFSP-100 did not induce agglutination of lymphocytes demonstrated by lectins in the same cells. These observations suggest that KFSP-100 may be a novel mitogen for B lymphocytes. The component (s) responsible for the B cell proliferation in KFSP-100 might be a factor gained by natural fermentation. None of the fractions of not fermented soybean paste prepared by the same methods demonstrate the same effect.
Agglutination
;
Ammonium Sulfate
;
Animals
;
B-Lymphocytes
;
Cell Proliferation
;
Fermentation
;
Filtration
;
Glycoproteins
;
Immunologic Factors*
;
Interleukin-12
;
Interleukin-6
;
Lectins
;
Lymphocytes
;
Macrophages
;
Membranes
;
Mice
;
Soybeans*
;
T-Lymphocytes
;
Ultrafiltration
5.A Case of Multiple Basal Cell Carcinoma.
Yean Sub JANG ; Kwang Joong KIM ; Eil Soo LEE ; Chong Ju LEE
Korean Journal of Dermatology 1988;26(5):768-773
We reoport a case of multiple basal cell carcinoma in a 51-year-old male who have taken a herb medication for right hemiplegia during 30 years. The patient had a 15-year history of the black colored, ulcerated nodules on left forehead and erythematous, protruded masses on back. Also, he had a 6-year history of black colored, ulcerated nodules on right temporal area of scalp and brownish, flat plaques on anterior chest, Biopsy specimens from lesions revealed typical histopathologic findings of the basal cell carcinoma. Wide excision with graft was done. One year later, he was expired due to lung carcinoma.
Biopsy
;
Carcinoma, Basal Cell*
;
Forehead
;
Hemiplegia
;
Humans
;
Lung
;
Male
;
Middle Aged
;
Scalp
;
Thorax
;
Transplants
;
Ulcer
6.A Case of Rectal Adenocarcinoma Metastatic.
Jong Min KIM ; Yean Sub JANG ; Tae Hoon CHO ; Eil Soo LEE
Korean Journal of Dermatology 1988;26(6):951-955
Adenocarcinoma metastatic to the skin usually originates in the lung, breast, large intestine or ovary. Cutaneous metastatic tumors from rectum or colon tend to appear in the abdominal or perineal area, but rarely appear in the perianal and genital skin. A 53-year-old female presented multiple nodules in and near the surgical scars of inguinal, pubie, vulvar, perianal areas and normal skin of left thigh two months after surgical removal of rectal adenocarcinoma. Biopsy specimens from the nodules of the perianal area and left thigh showed adenocarcinoma of well differentiated atruetures like the primary rectal carcinoma.
Adenocarcinoma*
;
Biopsy
;
Breast
;
Cicatrix
;
Colon
;
Female
;
Humans
;
Intestine, Large
;
Lung
;
Middle Aged
;
Ovary
;
Rectum
;
Skin
;
Thigh
7.Type I Allergy to House Dust Mite and Familial BACKGROUND of Respiratory Atopy in Patients with Atopic Dermatitis.
Ja Kyoung SHIN ; Dae Won KOO ; Chong Ju LEE ; Yean Sub JANG
Korean Journal of Dermatology 1995;33(6):1046-1052
BACKGROUND: Recent studies have suggested that house dust mite allergy is an important cause of the atopic dermatitis(A.D). However, it is not clear that. what factors may be related to the development of the mite illergy in patients with AD. OBJECTIVE: This study was done to see whether the presence of a familial background of RA implies a relationship to the mite allergy in AD. METHODS: Skin prick test and fluoroallergosorbent, test (FAST) with house dust mit,e were performed in 47 patients wih AD. RESULTS: 1. In comparison the esult of prick test with that of FAST to house dust mite antigen, it showed a concordance ra!e of 82%. And the prick test was more sensitive than the FAST. 2. The prevalence of positive FAST reactions was significantly increased in the patients with AD who had a family hitory of RA than those in patients with AD who had neither family or personal history of RA. 3. The level of specific IgE against house dust mite did not relate to the presence of family cr personal history of RA. 4. The prevalence of positive prick test results did not relate to the presence of family or personal history of RA. 5. The prevalence of positive FAST reactions, the level of specific IgE, and the rate of positive prick test results did not relate to the severity of skin involvement. 6. The most common allergens which caused positive skin reactions were house dust, cat fur, Dermatophagoides farinac, Dermatophagoides pteronyssinus, et al. Antigen score of prick test to 55 common antigens wa. significant increased in the patients with AD who had a family history of RA, but did not relat to the severity of skin involvement or the presence of personal history of RA. CONCLUSION: We may conclude that type I allergy to the house dust mit,e is not directly related to AD perse. This type of allergy to the mite seems to occur predominantly in those patient s with AD who have a farilial background of RA.
Allergens
;
Animals
;
Cats
;
Dermatitis, Atopic*
;
Dermatophagoides pteronyssinus
;
Dust*
;
Humans
;
Hypersensitivity*
;
Immunoglobulin E
;
Mites
;
Prevalence
;
Pyroglyphidae*
;
Skin
8.Congenital anterior urethral diverticulum
Hyun Sub JUNG ; Young Sun CHUNG ; Chee Jang SUH ; Jong Jin WON
Journal of the Korean Radiological Society 1985;21(5):845-848
Two cases of congenital anterior urethral diverticula which have occurred in a 4 year-old and one month-oldboys are presented. Etiology, diagnostic procedures, and its clinical results are briefly reviewed.
Diverticulum
9.Rescue endovascular treatment for rapid regrowth of aneurysm remnant on middle cerebral artery trunk after unsuccessful surgical clipping in patients with a ruptured cerebral aneurysm: A report of two cases
Hyun Wook CHO ; Donghwan JANG ; Hyo Sub JUN
Journal of Cerebrovascular and Endovascular Neurosurgery 2021;23(2):117-122
We report two rare cases treated with coiling after rapid regrowth (within a month) of an aneurysm remnant on the middle cerebral artery (MCA) trunk after incomplete surgical clipping. The first case, a 47-year-old man with subarachonoid hemorrhage (SAH) (Hunt-Hess grade II, Fisher grade III) underwent clipping of a ruptured saccular aneurysm with a wide neck on the right early frontal branch arising from the MCA trunk. Incomplete clipping with a 1 mm sized remnant neck was performed to avoid sacrificing the lenticulostriate artery. In a follow-up cerebral angiogram on postoperative day 30, a rapid regrowth of the aneurysm remnant was observed, and on that day, complete obliteration was obtained by rescue endovascular treatment. The second case, a 48-year-old healthy woman with SAH (Hunt-Hess grade II, Fisher grade III) underwent clipping of an anteroposteriorly projecting bilobulated aneurysm on the left M1. Incomplete clipping with a minimal remnant neck was performed. In follow-up digital subtraction angiogram on postoperative day 30, a rapid regrowth of an aneurysm remnant involving only a part of the initial aneurysm near the neck was observed, and on that day, complete obliteration was obtained by rescue coiling. These patients were both discharged without any neurological deficits.
10.Rescue endovascular treatment for rapid regrowth of aneurysm remnant on middle cerebral artery trunk after unsuccessful surgical clipping in patients with a ruptured cerebral aneurysm: A report of two cases
Hyun Wook CHO ; Donghwan JANG ; Hyo Sub JUN
Journal of Cerebrovascular and Endovascular Neurosurgery 2021;23(2):117-122
We report two rare cases treated with coiling after rapid regrowth (within a month) of an aneurysm remnant on the middle cerebral artery (MCA) trunk after incomplete surgical clipping. The first case, a 47-year-old man with subarachonoid hemorrhage (SAH) (Hunt-Hess grade II, Fisher grade III) underwent clipping of a ruptured saccular aneurysm with a wide neck on the right early frontal branch arising from the MCA trunk. Incomplete clipping with a 1 mm sized remnant neck was performed to avoid sacrificing the lenticulostriate artery. In a follow-up cerebral angiogram on postoperative day 30, a rapid regrowth of the aneurysm remnant was observed, and on that day, complete obliteration was obtained by rescue endovascular treatment. The second case, a 48-year-old healthy woman with SAH (Hunt-Hess grade II, Fisher grade III) underwent clipping of an anteroposteriorly projecting bilobulated aneurysm on the left M1. Incomplete clipping with a minimal remnant neck was performed. In follow-up digital subtraction angiogram on postoperative day 30, a rapid regrowth of an aneurysm remnant involving only a part of the initial aneurysm near the neck was observed, and on that day, complete obliteration was obtained by rescue coiling. These patients were both discharged without any neurological deficits.