2.The Study of Histopathologic Grade, PCNA and AgNORs Staining in the Recurrent Urinary Bladder Cancer.
Korean Journal of Pathology 1994;28(6):643-650
The prognosis of transitional cell carcinoma(TCC) of the urinary bladder is related to histopathologic parameters, among which the clinical stage and histopathologic grade are most important prognostic determiantors. Recently the immunohistochemical assessment of proliferating cell nuclear antigen(PCNA) and nucleolar organizer region number(AgNORs) can obtain the PCNA, and AgNORs stainings were studied in 55 the sequential biopsies of 22 recurrent TCCs of the urinary bladder. 6 cases showed the increased changes of grade, of which 5 cases was independently to the change of grade. The AgNORs in 18 cases showed increase in 10 cases. The comparison between PCNA count and AgNORs score according to grade was performed in the changes between grade II and III, both PCNA count and AgNORs score were increased with in crease of grade. However, The change of the PCNA count was stastically significant, but not AgNORs score.
Biopsy
3.A clinical study on acute appendicitis in children.
Eun Sub PARK ; Jae Man KIM ; Han Sun KIM
Journal of the Korean Society of Coloproctology 1993;9(1):57-65
No abstract available.
Appendicitis*
;
Child*
;
Humans
4.A Clinical Observation of Intussusception in Infants and Children.
Journal of the Korean Pediatric Society 1980;23(12):1024-1032
Intussusception is most frequent and emergency condition of abdomen in infancy and childhood. But the causation of that is uncertain. In the method of treatment, primary barium reduction was recommended. This is a clinical observation of 51 cases of intussusception from January 1973 to December 1977 at Han-Il Hospital. The result were summarized as follows; 1) In age incidence, 72.55% of the patients were under 1 year of age. The highest morbidity (54.90%) occurred between 6 months to 12 months. 2) Males were affected more often than females ; the ratio was 1.8 : 1. 3) In seasonal incidence, 31.37% of patients occurred in Spring. 4) In artificial fed partients, the incidence was higher than others (54.35%). 5) Among siblings the first baby was most frequently affected (49.02%). 6) In development states(their body weight) 43.14% of them were over 91th precentile. 7) The cardinal symptoms and signs on admission were vomiting (82.35%), mucous bloody stool(78.43%), abdominal pain and irritability(66.67%), and abdominal mass(58.82%). 8) Most common type of intussusception was ileo-colic(50.98%) 9) Etiologically 90.20% of cases were idiopathic, but only 9.80% had organic causes. 10) In 50.98% of cases, bariumm enema was performed successfully, and surgical management with manual reduction and segmental resection was performed in 47.06%. 11) The recurrence rate was 3.92%.
Abdomen
;
Abdominal Pain
;
Barium
;
Child*
;
Emergencies
;
Enema
;
Female
;
Humans
;
Incidence
;
Infant*
;
Intussusception*
;
Male
;
Recurrence
;
Seasons
;
Siblings
;
Vomiting
5.Effect Of the Polyethylene Wear On Osteolysis in Cementless Primary Total Hip Arthroplasty: Minimum 5 Years' Follow - Up Study.
Chang Dong HAN ; Wahn Sub CHOE ; Joo Hyung YOO
The Journal of the Korean Orthopaedic Association 1998;33(3):746-758
We measured poiyethylene wear radiographically in 85 cementless primary total hip arthroplasties by the modified technique of Livermore et al. All the patients were followed up for at least five years (mean, 6.31 years; range, 5 years-8 years 2 months). The mean extent of linear wear was 0.88mm (range, 0.0083-3.2839mm), and the mean rate of linear wear was 0.14mm/year(range, 0.00-0.47mm /year). The mean volumetric wear was 539.42mm (range, 5.11 2022.09mm), and the mean rate of volumetric wear was 87.69mm/year(range, 0.65-290.12mm/year). The polyethylene wear was correlated inversely with the patients age only, but was not influenced by weight or gender of the patients, Harris hip score, thickness of the polyethylene, the abduction angle of acetahular cup, or the duration of in situ implantation. Osteolysis developed in the femur of 34 hips(40%) and in the acetabulum of 11 hips(12.9%). Radiographic loosening was found in one case in the femur and none in the acetabul pm. The extent of polyethylene wear was significantly correlated with frequencies and sizes of the osteolytic lesion and was not directly associated with radiographic loosening of the prostheses. Calcar resorption was observed in 39 hips(45.9%) and was not associated with polyethylene wear. These results indicated that polyethylene wear of primary total hip arthroplasty should be considered one of major causes of osteolysis and has no direct relationship with prosthesis loosening. To reduce the extent of polyethylene wear, the material characteristics of polyethylene should be improved or new, durable, articulating materials should be researched.
Acetabulum
;
Arthroplasty
;
Arthroplasty, Replacement, Hip*
;
Femur
;
Hip
;
Humans
;
Osteolysis*
;
Polyethylene*
;
Prostheses and Implants
;
Prosthesis Failure
6.Congenital Pseudarthroses of Both Bones of the Forearm Associated with Neurofibromatosis: A Case Report
Seung Koo LEE ; Han CHANG ; Kwang Sub SHIN
The Journal of the Korean Orthopaedic Association 1988;23(6):1576-1580
The occurence of pseudarthroses associated with neurofibromatosis is a well documented phenomenon, with the majority of reported cases in the tibia but quite rare in forearm,Only ten cases in the English-literature and one case in Korean-literature of this lesion revealed appearing in the bones of the forearm till now. Of these, four in solitary pseudarthroses of the ulna(4.5.15), five in a solitary lesion of the radius(7.8.10.16.17), and only two cases was on the both bones of the forearm(9.14). We are presenting the case report of a Korean adult male with the clinical stigmata and a positive familial history of neurofibrormotosis who had congenital pseudarthroses of both the radius and ulna of the right forearm. Therefore, the present case is the third to be reported. We treated him with by production of an one-bone forearm using a dual a onlay bone graft positioned in neutral of supination and pronation. A stable, functional extremity with good union of pseudarthroses were encountered.
Adult
;
Christianity
;
Extremities
;
Forearm
;
Humans
;
Inlays
;
Male
;
Neurofibromatoses
;
Neurofibromatosis 1
;
Pronation
;
Pseudarthrosis
;
Radius
;
Supination
;
Tibia
;
Transplants
;
Ulna
7.Magnetic Resonance Arthrography in the evaluation of Anterior Glenohumeral Instability.
Jin Sub KIM ; Yong Wook PARK ; Jung Han YOO ; Yung Khee CHUNG ; Sung Han HA
The Journal of the Korean Orthopaedic Association 1998;33(5):1240-1247
Anterior glenohumeral instability is mainly due to the Bankart lesion and capsular stretch. The differentiation between the Bankart lesion and capsular laxity may not be readily apparent on clinical examination. So, increasing attention has been directed toward preoperative evaluation of the labral lesion and capsular laxity. MRI and MR Arthrogram of 55 shoulders, 40 stable shoulders and 15 unstable shoulders that were confirmed by arthroscopic surgery, were reviewed to evaluate the labral and capsular shapes, especially the lesions of labroligamentous complex. To evaluate and compare the capsular laxity, we measured the anterior capsular insertion type, capsular ballooning, capsular insertion angle and anterior band of inferior glenohumeral ligament. And the following results were obtained; 1) The shape of anterior labrum was varied in the superior, middle and inferior potions in 40 stable shoulders. The anterior labral lesions were shown as torn(eight cases), displaced(six cases) and no detectable labrum(one case), in 15 unstable shoulders. Also, there were a significant di fference in the evaluation of the anteior labrum shape between MRI and MR arthrography. 2) There were not a significant difference in the type III capsular insertion type, capsular ballooning and capsular insertion angle between the stable and unstable shoulders. However, it was found that the shape of the anterior band of the inferior glenohumeral ligament had definite difference between the two groups. And so, more experience and attention should be given for the accurate preoperative evaluation of the anterior labroligamentous complex in shoulder instability.
Arthrography*
;
Arthroscopy
;
Ligaments
;
Magnetic Resonance Imaging
;
Shoulder
8.Femoral Head and Neck Fractures developed in Avascular Necrosis of the Femoral Head.
Hyung Ku YOON ; Duck Yun CHO ; Soo Hong HAN ; Yong Sub HAN ; Ki Sik NAM
Journal of the Korean Hip Society 2006;18(1):79-83
Femoral head and neck fractures during the course of avascular necrosis are rare with only few reports in the English literature. Moreover, there are very few reports on an analysis of the patterns of these fractures. Four cases of femoral head fracture caused by minor trauma, which were quite different from the crescent fractures during the course of avascular necrosis were analyzed in regard to the underlying disease, causes, sites, types, directions, pattern of fractures and the injury mechanism of the fractures. The results are reported with special regard to the pattern of the stress fracture of the femoral head and neck during the course of avascular necrosis.
Fractures, Stress
;
Head*
;
Neck*
;
Necrosis*
9.Clinical Review of Surgical Geriatric Patients over 65 Years of Age.
Hyoung Sub OH ; Joon Kil HAN ; Kwang Chan LEE
Journal of the Korean Surgical Society 1998;54(1):129-135
In order to identify the relationship between the patient's age and the presence of another disease, and the postoperative complications and mortality, we reviewed the medical records of 6156 patients admitted to the Department of Surgery, Dae Jeon Eul Ji General Hospital, during the period from January 1991 through December 1995. There were 1546 geriatric patients(>65 years of age) and 4610 adult patients (age between 16 and 64). Six hundred sixty-five patients (43%) in the geriatric group had one or more concurrent diseases preoperatively, whereas 1127 patients (24.4%) in adult group did. Postoperative complications were more frequent in the geriatric group: 21.6% (310 patients) in the geriatric group vs 15.2%(217 patients) in the adult group. Geriatric patients who had more than one concurrent disease and who underwent an emergency operation showed a higher postoperative complication rate than those who had only one concurrent disease and who underwent elective surgery. The postoperative mortality was also higher in the geriatric group: 3.8%(48 patients) in the geriatric group vs 0.7% (32 patients) in the adult group. The most frequent cause of postoperative death in the geriatric group was sepsis. The geriatric patients who had a concurrent disease account for 16.4% of postoperative complications and 1.5% of the mortalities, whereas those who did not have any concurrent disease account for 2.67% and 0.2%, respectively. Among 1127 adult patients who had a concurrent disease, 124 (11.0%) had postoperative complications and 24 (2.2%) died postoperatively. In conclusion, the elderly patients more frequently had one or more concurrent diseases, and these patients had higher postoperative complication and mortality rates, especially after emergency operations. Accordingly, it is crucial for the surgeon to completely evaluate and manage any concurrent diseases in elderly patients preoperatively.
Adult
;
Aged
;
Daejeon
;
Emergencies
;
Hospitals, General
;
Humans
;
Medical Records
;
Mortality
;
Postoperative Complications
;
Sepsis
10.The effects of the fluoride concentration of acidulated buffer solutions on dentine remineralization.
Journal of Korean Academy of Conservative Dentistry 2009;34(6):526-536
The aim of this vitro-study is to evaluate the effects of fluoride on remineralization of artificial dentine caries. 10 sound permanent premolars, which were extracted for orthodontic reason within 1 week, were used for this study. Artificial dentine caries was created by using a partially saturated buffer solution for 2 days with grounded thin specimens and fractured whole-body specimens. Remineralization solutions with three different fluoride concentration (1 ppm, 2 ppm and 4 ppm) were used on demineralized-specimens for 7 days. Polarizing microscope and scanning electron microscope were used for the evaluation of the mineral distribution profile and morphology of crystallites of hydroxyapatite. The results were as follows : 1. When treated with the fluoride solutions, the demineralized dentine specimens showed remineralization of the upper part and demineralization of the lower part of the lesion body simultaneously. 2. As the concentration of fluoride increased, the mineral precipitation in the caries dentine increased. The mineral precipitation mainly occurred in the surface layer in 1 and 2 ppm-specimens and in the whole lesion body in 4 ppm-specimens. 3. When treated with the fluoride solution, the hydroxyapatite crystals grew. This crystal growth was even observed in the lower part of the lesion body which had shown the loss of mineral.
Bicuspid
;
Crystallization
;
Dentin
;
Durapatite
;
Electrons
;
Fluorides