1.Characteristics of protease produced by vibrio vulnificus and its effect on the activity of hemolysin.
Journal of the Korean Society for Microbiology 1992;27(3):207-213
No abstract available.
Vibrio vulnificus*
;
Vibrio*
2.Comparison of the depression and anxiety between the elderly in the home for the aged and those in the community.
Hyo Seok SEO ; Sung Duk JUNG ; Chang Su KIM
Yeungnam University Journal of Medicine 1992;9(2):256-268
This survey was conducted from January 1991 to May 1991. Two hundred and eight residents in 4 government supported homes for the aged and hundred and eleven living in the community in Taegu, Korea, were examined to evaluate the depression and the anxiety of the aged with combined anxiety and depression scale (CADS) and somatization symptom check list (SCL). There are no significant differences between residents in the home for the aged and those living in the community on the total scores of CADS and SCL. However, in the case of the total score of CADS of the female subjects in the home for the aged were significantly higher than those of the community residents. The elderly in the home for the aged tended to have pure depression, while community residents were likely to have anxiety and depression. Fifty-two subjects of home for the aged and sixty-nine of the community scored over 50 points of CADS, which indicates considerable depression or anxiety. In psychosocial factors, the subjects who in the following situations had statistically significant higher scores than others. The results were as follow. Poor health, unhappiness, unsatisfaction to the past occupation, pessimistic thought in future view for both group and unsatisfaction of the relationship with familiar people for the elderly in the community. The SCL scores of two groups subgrouped by under 49 and 50 on CADS showed significant differences between each subgroup on all of the SCL items. It could be suggested that somatic symptoms for the aged is a sign of depression.
Aged*
;
Anxiety*
;
Daegu
;
Depression*
;
Female
;
Homes for the Aged
;
Humans
;
Korea
;
Occupations
;
Psychology
3.Calcium overload is essential for the acceleration of staurosporine-induced cell death following neuronal differentiation in PC12 cells.
Experimental & Molecular Medicine 2009;41(4):269-276
Differentiation of neuronal cells has been shown to accelerate stress-induced cell death, but the underlying mechanisms are not completely understood. Here, we find that early and sustained increase in cytosolic ([Ca2+]c) and mitochondrial Ca2+ levels ([Ca2+]m) is essential for the increased sensitivity to staurosporine-induced cell death following neuronal differentiation in PC12 cells. Consistently, pretreatment of differentiated PC12 cells with the intracellular Ca2+-chelator EGTA-AM diminished staurosporine-induced PARP cleavage and cell death. Furthermore, Ca2+ overload and enhanced vulnerability to staurosporine in differentiated cells were prevented by Bcl-XL overexpression. Our data reveal a new regulatory role for differentiation-dependent alteration of Ca2+ signaling in cell death in response to staurosporine.
Animals
;
Calcium/*metabolism
;
Caspase 3/metabolism
;
Cell Differentiation/*physiology
;
DNA Fragmentation
;
Mitochondria/metabolism
;
*Neurons/cytology/drug effects/physiology
;
*PC12 Cells/cytology/drug effects/physiology
;
Rats
;
Staurosporine/*pharmacology
;
bcl-X Protein/metabolism
4.Periprosthetic Fracture after Total Shoulder Arthroplasty
Nam Su CHO ; Myung Seo KIM ; Jae Woo YANG ; Jeung Hwan SEO ; Dong Won SEO
Journal of the Korean Fracture Society 2020;33(2):118-123
Periprosthetic humeral fractures in patients with total shoulder arthroplasty are rare and difficult to treat. With the significant increase in the number of older patients who have undergone total shoulder arthroplasty in recent years, an increase in the number of periprosthetic shoulder fractures can be estimated. The decisions of treatment have to be taken individually, depending on the stability of the prosthesis, fracture location, and bone quality. On the other hand, there are limited data for treatment guidance and outcomes. This paper reviews the risk factors, classification, treatment, and outcomes of periprosthetic humeral fractures.
5.Progressive Dynamic Equinovarus Deformity in Hereditary Spastic Paraplegia: A Case Report.
Journal of Korean Foot and Ankle Society 2004;8(1):111-113
In neurogenic equinovarus deformity, surgical intervention such as tendon transfer or osteotomy can be expected to improve symptoms. However, in rare cases of hereditary spastic paraplegia, the deformity and paralysis gradually progress. So limited operation and early post-operative rehabilitation are preferred to aggressive operation. We would like to report our clinical experience with one case of hereditary spastic paraplegia patient with reference review. A 40 year-old male, given tendon transfer of ankle and foot and tendo achilles lengthening 10 years ago, complained about aggravated spastic paraplegia which resulted in dynamic equinovarus and limited walking ability since his operation. Family history showed limited walking ability of his father with gradually progressing spastic paralysis and he was diagnosed as hereditary spastic paraplegia type I. We had performed a limited operation such as tendo achilles and tibialis posterior lengthening to induce plantigrade standing and walking with crutch. As a result, the patient was able to maintain a stabilized standing posture and walk after the operation. Hereditary spastic paraplegia presents with a progressive paralysis which limits rehabilitation after tendon transfer, and the symptoms can be aggravated. Therefore, considering potential hereditary neurogenic disorders in paients with equinovarus deformity and performing limited operative procedures seem to be important.
Adult
;
Ankle
;
Clubfoot*
;
Congenital Abnormalities*
;
Fathers
;
Foot
;
Humans
;
Male
;
Muscle Spasticity
;
Osteotomy
;
Paralysis
;
Paraplegia
;
Posture
;
Rehabilitation
;
Spastic Paraplegia, Hereditary*
;
Surgical Procedures, Operative
;
Tendon Transfer
;
Walking
6.In Thyroid Cancer Patients, Is Preoperative FNAB-C Reliable for Prediction of Lateral Cervical LN Metastasis?.
Su Han SEO ; Jung Hun LEE ; Euy Young SOH
Korean Journal of Endocrine Surgery 2014;14(2):76-80
PURPOSE: The goal of this study was to evaluate the diagnostic accuracy of preoperative fine needle aspiration biopsy cytology (FNAB-C) in predicting lateral lymph node metastasis in papillary thyroid cancer patients. METHODS: A total of 592 patients who underwent thyroid cancer surgery and intra-operative lateral cervical LN frozen section or RND, from January 2002 to December 2011, were evaluated retrospectively. Among them, 228 cases had suspicious findings in FNAB-C of lateral nodes. We reviewed their radiological and pathological reports. RESULTS: Intra-operative frozen section examination was performed in 540 cases and RND was performed in 314 cases. This study included 534 women (83.4%) and 106 men (16.6%). Patients' ranged in age from 9 to 83 years (mean, 45.65 years). FNAB-C was performed in 228 cases. The sensitivity and specificity of FNAB-C was 71.5% and 78.6%, respectively; 35.9% of cases had a false negative result. The combination of FNAB-C and intra-operative frozen section test sensitivity and specificity was 87.2% and 93.6%, respectively. CONCLUSION: The results for sensitivity in FNAB-C actually appear low, and false negative results were very high. In papillary thyroid cancer in patients with FNAB-C, even if the result is negative, if lymph node metastasis is suspected based on radiologic evidence, frozen section examination should be performed for determination of metastasis.
Biopsy
;
Biopsy, Fine-Needle
;
Female
;
Frozen Sections
;
Humans
;
Lymph Nodes
;
Male
;
Neoplasm Metastasis*
;
Retrospective Studies
;
Sensitivity and Specificity
;
Thyroid Neoplasms*
7.Effect of Microsurgical Varicocelectomy on Oligospermic or Asthenospermic Patients with Subclinical Varicocele.
Korean Journal of Urology 2005;46(8):815-818
Purpose: The object of this study was to attempt to assess the effects of microsurgical varicocelectomy in subclinical oligospermic or asthenospermic patients. Materials and Methods: Fourteen oligospermic or asthenospermic patients, with subclinical varicocele, were diagnosed by color Doppler ultrasound, between October 2001 and March 2004. All patients underwent an inguinal microsurgical varicocelectomy. Semen analyses were performed 4 months later, and compared with the preoperative data. Results: The mean patient and spouse ages were 31.9+/-2.09 (range 29 to 36) and 29.9+/-1.85 (range 27 to 33) years, respectively. Comparison of the semen parameter before and after surgery revealed significant improvement of the sperm count. The mean sperm count increased from 33.09+/-31.96 to 60.74+/-56.27 million/ml (p<0.05). There were no significant statistical differences in the pH, motility, morphology and viability on the semen analysis. 4 of the 14 patients achieved spontaneous pregnancy (28%) after 7 to 10 months, and 4 achieved pregnancy, with in vitro fertilization (28%), 10 to 30 months later. Conclusions: A microsurgical varicocelectomy in oligospermic or asthenospermic patients, with subclinical varicocele, significantly increased their sperm count. In infertile couples, with no specific problem other than subclinical varicocele, it is worth while performing a microsurgical varicocelectomy.
Family Characteristics
;
Fertilization in Vitro
;
Humans
;
Hydrogen-Ion Concentration
;
Infertility, Male
;
Male
;
Pregnancy
;
Semen
;
Semen Analysis
;
Sperm Count
;
Spermatozoa
;
Spouses
;
Ultrasonography
;
Varicocele*
8.A Study on the Verification of the Profile of Seo's Elderly Stress Scale (SESS).
Hyun Mi SEO ; Su Jeong YU ; Yang Sook HAH
Journal of Korean Academy of Nursing 2001;31(1):94-106
The purpose of this study was to verify the use of Seo's Elderly Stress Scale (SESS), which was developed in 1996. Through the modified tool, it is possible to examine the stress of Korean elders and to contribute to the welfare of them. The subjects were 350 elders over 65 years old who live in Seoul, Kwang-Ju, Yang-Ju Gun Kyung-ki Do, Ui-Jong Bu, and Young-Am Kun, Jeun-Ra Nam Do. the data of 331 elders (94%) were analyzed. Data were collected between January and March in 1996 and analyzed using the SPSS Win 8.0. The result are as follows: 1. Items with low correlation with the total items were removed. So 27 items were removed and 37 items remained. This 37 items were death in the family and/or close friends, family member's behavior not meeting expectations, marriage of daughter, marriage of son, friction with daughter- in-law, argument among children, children refuse to live with parent, children leaving home, sex injury or accident, in frequest visits from children and grandchildren, providing care for your daughter or daughter-in-law post-partum, decrease in decision making and authority in home, Lunar new year and the harvest featival, house sitting, working in the house, performing a sacrificial rite, missed birthday, not living with the eldest son, decreased eyesight, decreased strength, decreased memory, sleep pattern changes, thoughts about death, loneliness, decreased hearing, change of dental condition, change in your diet or eating style, difficulty in self care, moving because of disease or aging, argument with friend or neighbour, travel, dealing with the procedure of heritage, loss of money or property, not enough pocket money, hearing on elderly neglect in television or radio, hope of going home and ignorant from others. 2. Overlapped items were discussed by colleagues and were modified. 'marriage of daughter' and 'marriage of son' were modified in 'marriage of children'. 'self injury or accidents' and 'family accidents' were modified in to self or family accidents. 3. Factor analysis was done in order to identify validity and three factors were obtained from the result. The first factor familial relation area, included 17 items. The second factor, physical area, included 9 items. The third factor, psycho-socio-economic area, included 9 items. Cronbach coefficient alpha for the 35 items was .923. 4. Pearson's correlation was .704 between SESS and SOS (Symptoms of Stress) in order to confirm construct validity. Based on the result, the following is suggested; 1. The modified SESS needs to be reverified with elder. 2. Korean elder's health promotion can be made by development of stress intervention which was accurately measured with SESS.
Aged*
;
Aging
;
Child
;
Decision Making
;
Diet
;
Eating
;
Factor Analysis, Statistical
;
Friction
;
Friends
;
Gwangju
;
Gyeonggi-do
;
Health Promotion
;
Hearing
;
Hope
;
Humans
;
Loneliness
;
Marriage
;
Memory
;
Nuclear Family
;
Parents
;
Self Care
;
Seoul
;
Television
9.Nonspecific Empirical Medical Therapy with Acetylcarnitine Effective in Oligoasthenospermic Men?.
Jong Woo KIM ; Jae Seok LEE ; Jeong Su PARK ; Won Tae KIM ; Ju Tae SEO
Korean Journal of Fertility and Sterility 2004;31(3):177-182
PURPOSE: To determine the efficacy of CarnitilR (acetylcarnitine, Hanmi, Korea) therapy in idiopathic oligoasthenospermic men. MATERIALS AND METHODS: Forty-four subfertile men with abnormal semen parameters were treated between March, 2003 and March, 2004 with 3 g of CarnitilR daily for 3 months. Changes in semen parameters were evaluated 3 months after this therapy. RESULTS: The mean age was 34.2 years and the mean follow-up duration was 3.7 months. In asthenospemic patients (n=28), semen analysis before and after CarnitilR treatment showed an increase in volume (2.64+/-1.65 ml vs. 3.10+/-1.60 ml), motility (35.1+/-17.7% vs. 45.9+/-20.4%) and viability (51.4+/-20.3% vs. 59.3+/-13.6%) respectively. In oligoasthenospermic patients (n=16), semen analysis before and after CarnitilR treatment showed an increase in sperm count (10.7+/-54.4 million/ml vs. 38.4+/-32.5 million/ml) respectively. CONCLUSIONS: These results suggested that in idiopathic oligoasthenospermic men the empirical medical therapy with acetylcarnitine may be considered as primary treatment.
Acetylcarnitine*
;
Carnitine
;
Follow-Up Studies
;
Humans
;
Infertility, Male
;
Male
;
Semen
;
Semen Analysis
;
Sperm Count
10.Pars Plana Vitrectomy Combined with Anterior Capsule-Sparing Lensectomy Clinical Report of 43 Cases.
Man Seong SEO ; In Seob LIM ; Jin Soo SU
Journal of the Korean Ophthalmological Society 1996;37(11):1865-1877
We performed pars plana vitrectomy combined with anterior capsule-sparing lensectomy on forty three eyes WJth coexisting cataract and vitreoretinal disease and followed up more than 6 months. Preoperative vitreoretinal diseases consisted of nondiabetic vitreous hemorrhage (thirteen eyes), retained metallic intraocular foreign bodies (nine eyes), posterior uveitis (nine eyes), proliferative diabetic retinopathy (seven eyes) and rhegmatogenous retinal detachment (five eyes) . Thirty six eyes (84%) revealed the visual acuity of 0.1 or less before operation. Thirty eight eyes (88%) could get a better visual acuity after operation than before operation. Posterior chamber intraocular lenses were implanted to thirty eight eyes. The severity of anterior capsular opacity showed a statistically significant difference between the eyes with injection of intraocular gas or silicone oil and them without injection of that (p=0.004). In this study, we can find that the technique of pars plana vitrectomy combined with anterior capsule-sparing lensectomy would be recommendable and the anterior capsular opacity may have relation with intraocular gas or silicone oil.
Cataract
;
Diabetic Retinopathy
;
Foreign Bodies
;
Lenses, Intraocular
;
Retinal Detachment
;
Silicone Oils
;
Uveitis, Posterior
;
Visual Acuity
;
Vitrectomy*
;
Vitreous Hemorrhage