No abstract available.
Electrons* ; Positron-Emission Tomography*

No abstract available.
Autoradiography* ; Brain* ; Rats, Wistar* ; Receptors, Muscarinic*

No abstract available.
Diagnosis* ; Graves Disease* ; Korea*

Squamous cell carcinoma has occasionally been encountered in orthopedic practice as a complication of chronic osteomyelitis, burn scar and other lesions. The possible occurrence of this secondary change impose difficulty in the diagnosis and management of chronic orthopedic diseases. During 11 years from 1966 to 1976, 16 cases of squamous cell carcinoma were confirmed by histopathological examination and the results of clinical observation on them are summarized here. l. Of 16 patients, men were 15 and woman one. Their average age was 51.3 years 2. The primary lesions in which this malignancy developed were osteomyelitis (5 cases), and scar (5 cases), and scar after extensive laceration (2 cases). In one case no primary lesion was present. 3. Average duration of symptomatology of the primary lesion was 35.4 years in osteomyelitis and 31.2 yeary in burnscar. 4. Location of the lesion was in lower extremity in 15 cases, eight of which were in the leg. 5. Methods of treatment undertaken were; amputation (10 cases), chemotherapy (2 cases), chemotherapy and irradation (1 case). In three no treatment was done because of refusal. 6. The follow-up study was possible in five of them. Of four cases amputated, one was well alive for two years after ablation with no evidence of metastasis, the others two showed spread, to inguinal nodes in one and ribs in the other, after two years and the fourth died of unknown disease after two years. The fifth died, after initial remission with chemotherpy and irradation, of lung cancer after two years.
Amputation ; Burns ; Carcinoma, Squamous Cell ; Cicatrix ; Diagnosis ; Drug Therapy ; Epithelial Cells ; Female ; Follow-Up Studies ; Humans ; Lacerations ; Leg ; Lower Extremity ; Lung Neoplasms ; Male ; Neoplasm Metastasis ; Orthopedics ; Osteomyelitis ; Ribs

Angioedema is a disorder characterized by well-demarcated nonpitting edema involving the tongue, floor of the mouth, larynx, lips, and face. The incidence of angiotensin converting enzyme(ACE) inhibitor related angioedema has been reported to be about 0.1% to 0.2%, and the time of onset is usually during the first week of therapy. These ACE inhibitors include captopril, enalapril, and lisinopril. A 53-year old man with an 8 month history of hypertension previously controlled with atenolol, was presented to the dermatologic department with angioedema of the face and tongue. He had begun therapy with captopril one day before this episode. Even though he was treated with epinephrine and methylprednisolone sodium succinate, the edema gradually progressed and finally dyspnea developed. He was urgently intubated and treated with steroids and pheniramine maleate in the intensive care unit. The edema resolved after 24 hours.
Angioedema* ; Angiotensin-Converting Enzyme Inhibitors ; Angiotensins ; Atenolol ; Captopril* ; Dyspnea ; Edema ; Enalapril ; Epinephrine ; Humans ; Hypertension ; Incidence ; Intensive Care Units ; Larynx ; Lip ; Lisinopril ; Methylprednisolone Hemisuccinate ; Middle Aged ; Mouth ; Pheniramine ; Steroids ; Tongue

No abstract available.
Antibodies, Monoclonal* ; Blood Cells*

A survey was conducted by the staff of the Dept. of Preventive Medicine, Kyung Hee University, School of Medicine, from April through May 1971, on such events as delivery, death, abortion and family planning. The survey directed to a total population 6,552 (Male 3,133; Female 3,419) residing in this area (1,262 households) led us to the following findings : 1) Two year averages of crude birth rate, crude death rate and natural increase rates were 24.9, 5.0 and 19.9 respectively. 2) Infant death rates for the years 1969 and 1970 were 13.2 and 5.8 respectively, mean for the two year period being 9.3. 3) Hospital deliveries rated 68.5 percent, Home deliveries 28.4 percent and deliveries at midwives' offices 2.7 percent. 4) Deliveries other than hospital and midwives' office deliveries were found to be attended more often by mothers. 5) About 41.4 percent of all pregnant women during last two years received prenatal care once or more. 6) The induced abortion rate was 6.7 percent in 1969 and 7.5 percent in 1970. 7) The spontaneous abortion rate was 1.1 percent in 1969 and 1.4 percent in 1970. 8) Hypertension was the most frequent cause of adult death(21.6%). 9) The rate of current practice in family planning was 43.3 percent of all women.
Abortion, Induced ; Abortion, Spontaneous ; Adult ; Birth Rate ; Family Planning Services ; Female ; Humans ; Hypertension ; Infant ; Mortality ; Mothers ; Parturition* ; Population Growth ; Pregnancy ; Pregnant Women ; Prenatal Care ; Preventive Medicine

A survey was conducted by the staff of the Dept. of Preventive Medicine, Kyung Hee University, School of Medicine, from April through May 1971, on such events as delivery, death, abortion and family planning. The survey directed to a total population 6,552 (Male 3,133; Female 3,419) residing in this area (1,262 households) led us to the following findings : 1) Two year averages of crude birth rate, crude death rate and natural increase rates were 24.9, 5.0 and 19.9 respectively. 2) Infant death rates for the years 1969 and 1970 were 13.2 and 5.8 respectively, mean for the two year period being 9.3. 3) Hospital deliveries rated 68.5 percent, Home deliveries 28.4 percent and deliveries at midwives' offices 2.7 percent. 4) Deliveries other than hospital and midwives' office deliveries were found to be attended more often by mothers. 5) About 41.4 percent of all pregnant women during last two years received prenatal care once or more. 6) The induced abortion rate was 6.7 percent in 1969 and 7.5 percent in 1970. 7) The spontaneous abortion rate was 1.1 percent in 1969 and 1.4 percent in 1970. 8) Hypertension was the most frequent cause of adult death(21.6%). 9) The rate of current practice in family planning was 43.3 percent of all women.
Abortion, Induced ; Abortion, Spontaneous ; Adult ; Birth Rate ; Family Planning Services ; Female ; Humans ; Hypertension ; Infant ; Mortality ; Mothers ; Parturition* ; Population Growth ; Pregnancy ; Pregnant Women ; Prenatal Care ; Preventive Medicine

No abstract available.
Ear, Middle*

BACKGROUND: Insulin resistance syndrome has been proposed as a major promotor of atherosclerotic disease and earlier studies have implied the hyperinsulinemia itself may enhance coronary vasomotor tone. In patients with vasospastic angina, previous studies have been inconclusive whether to basal coronary artery tone is elevated at the spasm related and nonspasm related artery. This study was performed to investigate whether basal coronary artery tone is elevated ans insulin resistance syndrome correlates to vasospastic angina. If insulin resistance syndrome correlates to vasospastic angina, we also investigated whether insulin resistance syndrome correlates to basal coronary artery tone. METHODS: The study comprised 27 patients with vasospastic angina(M/F ; 19/8, mean age ; 52+/-2 year) and 21 control subjects with atypical chest pain(M/F ; 9/8, mean age ; 47+/-3 year). We assessed basal coronary artery tone by obtaining the percent increase in coronary artery diameter induced by nitroglycerin and also examined glucose and insulin response to an oral glucose load of 75g. RESULTS: 1) There were no significant differences in body surface area, abdominal hip ratio, body mass index, incidence of hypertension, lipid profile, von-Willebrand factor, fibrinogen, and microalbumin except smorking incidence [vasospastic angia ; 16(50%) vs control ; 5(24%), p<0.05)] between vasospastic angina group and control. 2) Basal coronary artery tone was greater at the nonspastic site of the spasm-related artery(28.1+/-2.2% vs 13.1+/-0.9%, p<0.0001) and non-spasm related artery(23.7+/-1.6% vs 13.1+/-0.9, p<0.0001) in the patients with vasospstic angina than in control subjects. In the patients with vasospastic angina, high activity group had a greater basal coronary artery tone than low activity group at the nonspastic site of the spasm-related artery(31.7+/-2.6 vs 20.4+/-2.7%, p<0.001) and non-spasm related artery(26.8+/-2.0 vs 19.4+/-5.8%, p<0.001). 3) Plasma glucose and serum insulin response to an oral glucose load were similar between vasospastic angina group and control subjects, and glucose area, insulin area, and insulinogenic index(delta sigma Glucose / delta sigma Insulin)(330+/-12 vs 328+/-20 mg/dl *hour, 107+/-14 vs 96+/-17uU/ml*hour, and 2.18+/-0.33 vs 2.63+/-0.46, respectively, p=NS) also did not between both groups. 4) Two group did not differ siginificantly in the prportion of glucose intolerance but glucose area and insulin area were significantly high in vasospastic angina patients with glucose intolerance than in control subjects with normal glucose tolerance(366+/-22 vs 257+/-17mg /dl*hour, 127+/-19 vs 52+/-15uU*hour, respectively, p<0.05), but basal coronary artery tone did not differ significantly between vasospastic angina patients with glucose intolerance and control subjects with normal glucose tolerance. CONCLUSION: 1) These results revealed that basal coronary artery tone is elevated at the nonspastic site of the spasm related artery and non-spastic vessel, and the disease activity associated with elevated basal coronary artery tone in vasospastic angina. 2) But these results did not reveal the correlation of hyperinsulinemia with vasospastic angina, and so we did not determine the role of hyperinsulinemia as a pathogenesis of coronary spasm and the relation between hyperinsulinemia and basal coronary artery tone.
Arteries ; Blood Glucose ; Body Mass Index ; Body Surface Area ; Coronary Vessels* ; Fibrinogen ; Glucose ; Glucose Intolerance ; Hip ; Humans ; Hyperinsulinism ; Hypertension ; Incidence ; Insulin Resistance* ; Insulin* ; Nitroglycerin ; Spasm ; Thorax