No abstract available.
Heart Rate* ; Heart Septal Defects, Ventricular* ; Heart* ; Humans ; Hypertension, Pulmonary* ; Infant*

Rosai-Dorfman disease (RDD) is a rare type of benign histiocytosis characterized histologically by intracellular engulfment of lymphocytes. Extranodal RDD may occur as a part of generalized process involving lymph nodes or may involve extranodal sites independent of the lymph node status. We have experienced a case of extranodal Rosai-Dorfman disease of the nose as an initial lesion prior to nodal involvement. The patient was a 20-year-old woman who complained of nasal obstruction for 4 years, remotely, and left submandibular mass for 3 months, recently. Histologically, the lesion taken from nasal cavity, submandibular gland and left upper jugular lymph node all showed an heavy infiltrate consisted of plasma cells, lymphocytes and sheets of macrophages with abundant pale cytoplasm, which replaced organ architecture. The associated focal fibrosis made it difficult to differentiate from inflammatory pseudotumor. Some macrophages demonstrated phagocytosis of lymphocytes, plasma cells and occasionally neutrophils. The macrophages were strongly positive for S-100 protein.
Cytoplasm ; Female ; Fibrosis ; Granuloma, Plasma Cell ; Histiocytosis ; Histiocytosis, Sinus* ; Humans ; Lymph Nodes ; Lymphocytes ; Macrophages ; Nasal Cavity ; Nasal Obstruction ; Neutrophils ; Nose* ; Phagocytosis ; Plasma Cells ; S100 Proteins ; Salivary Glands* ; Submandibular Gland ; Young Adult

Peripheral T-cell lymphoma is the generic group given to a family of tumors composed of neoplastic lymphocytes with phenotypic features of peripheral T-cells. Certain peripheral T-cell lymphomas develop a hemophagocytic syndrome that mimics malignant histiocytosis, both clinically and pathologically. We experienced a case of nasal T-cell lymphoma, histologically mimicking malignant histiocytosis in a 40-year-old male. The chief complaints were nasal obstruction and intermittent mild fever. Mild anemia, elevated SGOT and SGPT, polyclonal gammophthy, and moderate hepatomegaly were present. Two weeks later was present an enlarged cervical lymph node. The biopsied nasal mass showed angiocentric and angiodestructive peripheral T-cell lymphoma withextensive necrosis and marked erythrophagocytosis by non-neoplastic histiocytes. Subsequently, cervical lymph node was biopsied, which showed peripheral T-cell ltmphoma with extensive necrosis and erythrophagocytosis as well. The atypical lymphoid cells revealed pan-T(+), but CD4(-) and CD8(-), whereas the reactive histiocytes showed lysozyme(+), immunohistochemistry.

The gastric carcinoma shows various molecular and genetic alterations in its development and progression. There are evidences that the changes of the expression of cell adhesion molecules affect the morphogenesis of the tumor as well as the tumor progression and metastasis. The purpose of this study is the evaluation of the expression pattern of a cell adhesion molecule, E-cadherin, and a tumor suppression gene, p53, by immunohistochemical stain and the relationship of their expressions with clinicopathologic findings in gastric adenocarcinoma tissue. The E-cadherin expression was absent or reduced in 93 cases (73.2%) and p53 was positive in 98 cases (77.2%) of 127 gastric adenocarcinomas. The frequency of reduced E-cadherin expression was significantly higher in poorly differentiated adenocarcinomas (p=0.04) and in diffuse type (p=0.01), but that of p53 positivity was not significantly correlated with tumor differentiation. Both proteins showed no correlation with depth of invasion, lymph node and distant metastasis, and tumor stage. There was no correlation between E-cadherin and p53 expression. This study indicates that the altered expressions of E-cadherin and p53 are associated with the development of intestinal and diffuse types of gastric adenocarcinoma and the differentiation of the gastric adenocarcinoma is affected by cell adhesion mediated by E-cadherin, but the modes of tumor progression and metastasis are not affected by E-cadherin and p53.
Adenocarcinoma* ; Cadherins* ; Cell Adhesion ; Cell Adhesion Molecules ; Genes, p53 ; Immunohistochemistry ; Lymph Nodes ; Morphogenesis ; Neoplasm Metastasis ; Stomach Neoplasms

No abstract available.

No abstract available.
Dentures*

PURPOSE: This study is a correlative study to assess the relationships of fatigue, stress, and burnout among the pregnant nurses in hospital. METHODS: The subjects in this study were 103 nurses aged between 22 and 40 who were confirmed as pregnant by the OBGY (Obstetrics and Gynecology) hospital and working at medical facilities located in J-province of G city during the period of July 15 through September 15, 2010. RESULTS: The level of fatigue of pregnant nurses showed an average of 5.60 out of 10 points, and the level of stress showed an average of 25.91. In terms of burnout, the average was 2.72 out of 5 points. The results of the correlative study to assess relationships among fatigue, stress and burnout showed significant positive correlation between burnout and fatigue (r=.47, p<.001) and stress (r=.53, p<.001) and between stress and fatigue (r=.58, p<.001). Therefore, the results show that increased level of fatigue and stress leads to increased level of burnout. CONCLUSION: The results of the study showed that higher level of fatigue and stress led to higher level of burnout. Therefore, to minimize the burnout of pregnant nurses, many efforts are required in the hospital policy and for the strategies to reduce burnout.
Aged ; Fatigue ; Humans

The purpose of this study was to understand and describe experience of the persons with colostomy using ethnographic method. Nine patients were interviewed by authors to explore the experience of the persons with colostomy. The data were collected using informal and in-depth interview, field notes, and medical records. The results were as follows : 1. The ostomates had experienced various physical and psychososcial difficulties in daily life. 1) The physical difficulties include the problems in the management of pouch, a formation of gas, skin irritation, diet control, sexual life, the loss of the sense of defecation, and fatigue. 2) The psychosocial difficulties were anxiety, a sense of disability, a feeling of shame being unable to accept the colostomy, a change in dressing, an economic burden, a withdrawal from social life, a burden of colostomy care, and a burden of sexual life. 2. The process of coping with these difficulties includes positive attitude to colostomy, the acceptance of colostomy care, and the mastery of colostomy care. 1) The positive attitude to colostomy was accomplished through personifying colostomy and positive thinking. 2) The acceptance of colostomy care was accomplished through physical recovery, passive acceptance, and a sense of independence. 3) The mastery of colostomy care was accomplished through diet control, acquirement of self care skills of colostomy. The results of the study might help nurses and other health care workers develop effective nursing interventions for ostomates by understanding ostomates' problems and their coping strategies.
Anxiety ; Bandages ; Colostomy ; Defecation ; Delivery of Health Care ; Diet ; Fatigue ; Humans ; Medical Records ; Nursing ; Self Care ; Shame ; Skin ; Thinking

Elastofibroma is a peculiar tumor-like lesion which manifests as a slowly growing, solid, ill-defined mass of fibroelastic tissue occurring almost exclusively in elderly persons. It has been found in the ,,ubscapular region but rare examples have also been found in other locations. We experienced a case of elastofibromatous lesion of the stomach. The lesion was incidentally found in a 71 -year-old woman during an operation of cholecystectomy due to chronic cholecystitis and choledocholithiasis. The lesion was a relatively well-defined but not encapsulated small nodule, 0.7 cm in diameter, at submucosal layer of gastric pylorus. Histologically the nodular mass consisted of abundant acellular collagen fibers containing numerous elastofibroma fibers.
Female ; Humans

No abstract available.
Aged* ; Humans ; Korea*