No abstract available.
Fosinopril* ; Humans ; Hypertension*

No abstract available.
Nucleic Acids*

No abstract available.
Latency Period (Psychology)* ; Osteogenesis, Distraction* ; Rabbits*

Spinal stenosis was defined as any type of narrowing of the vertebral canal, nerve canals or intervertebral foramina. It is difficult to diagnose spinal stenosis due to obscure symptoms and signs, and there is not established theory on its surgical treatment. Two hundred and three patients who had been treated surgically for lumbar spinal stenosis between 1979 and 1985 at Department of Orthopedic Surgery, Seoul National University Hospital, were studied in an attempt to define the etiology and the diagnosis, and to assess the results of surgical treatment. They were followed up from 1 year to 8 years with average duration of 3.5 years. 1. Degenerative change in the lumbar spine was the principal etiologic factor in 142 patients (70.0%) Spondylolisthesis was found in 47 patients (23 1%). 2. Back pain(81.3%) and intermittent claudication(71.4%) were the predominant symptoms, and sensory (61.1%) and motor(59.6%) deficit were the leading signs. Limitation of straight leg raising was observed only in 12.3%. 3. The most common myelographic finding was hourglass defect(38.4%) and that of CT was facet joint hypertrophy(97.6%). Preoperative CT with myelographic findings were confirmed intraoperatively in 97.4%, revealing their diagnostic significance. 4. Total laminectomy combined with foraminotomy and posterolateral fusion was the most frequently employed procedure and performed in 153 patients(75.4%). 5. The results were classified as excellent or good in 88.2%. Whether or not Knodt rod was used for internal fixation, there was no statistically significant difference between the two groups in reation to the results(P>0.05). Factors for satisfactory results were adequate decompression and posterolateral fusion with sufficient bone graft.
Decompression ; Diagnosis ; Foraminotomy ; Humans ; Laminectomy ; Leg ; Orthopedics ; Seoul ; Spinal Stenosis ; Spine ; Spondylolisthesis ; Transplants ; Zygapophyseal Joint

The electrical burns constitute a unique type of thermal injury and usually consist of a limited area of cutaneous burn, but associated with deep muscle damage of variable extent. The deep tissue destruction resulting from such injury leads to high incidence of amputation. So electrical burns are different from other types of injuries requiring individualized and varied methods of treatment, such as early fasciotomy, repeated debridement, wound coverage and technique of amputation. During 5 years from Jan. 1988 to Dec. 1992, we experienced 310 cases of electrical burn. We analyzed these cases on the aspects of functional result and necessity of amputation according to the treatment variability. The result showed the extent of burn in amputation group was 11.6%, salvage group 13.1%, with no difference of extent between 2 groups(p>0.05, by qui square test). When the fasciotomy was done earlier than 12 hours after injury showed 39.1% of more than good functional result, when later than 12 hours 7.7% of more than good, that is, earlier fasciotomy resulted in better function(p < 0.05, qui square test). The amputation rate was 23.9% during the last 5 years which was a marked improvment when compared to the previous ten years(32.4%). From these results we concluded that in order to reduce the rate of amputation and to improve the function of patients, early fasciotomy, early repeated debridement and wound coverage is necessary.
Amputation ; Burns ; Debridement ; Humans ; Incidence ; Wounds and Injuries

The percutaneous pinning is a simple, effective method for the treatment of displaced supracondylar fractures of the humerus in children. But there is some controversy in the number of pins used and the method of pin insertion. The cross pinning method provides more stability at the fracture site but the risk of ulnar nerve damage is higher than in lateral pinning method, The senenty-one displaced extension type supracondylar fractures were treated by closed reduction and percutaneous cross pinning from January 1991 to October 1994. Among them, the medial pin was inserted in elbow extension in twenty-eight cases and in forty- three cases the medial pin was inserted in elbow flexion. Ulnar nerve injury occured postoperatively in six cases, in which the pin was inserted with the elbow in flexion position. These results may suggest that when percutaneous cross pinning method is selected to fix the supracondylar fracture of the humerus, it would be safer to insert one or two lateral pins with the elbow in full flexion position followed by one medial pin in extension position in order to reduce the risk of loss of reduction and ulnar nerve damage.
Child ; Elbow ; Humans ; Humerus ; Methods ; Ulnar Nerve

No abstract available.
Hip* ; Pyomyositis*

Rhinocerebral mucormycosis is a very rare, but mostly fatal fungal infection, usually found in diabetic or other immunocompromised hosts. It has a characteristic pattern of spread, invasion of vessel walls with subsequent local thrombotic infarction or direct invasion. But we found two cases contrast to these typical patterns of spread. Our cases initially originated in the nasal cavity and progressed to the cavernous sinus in usual manner, but after then, extended along the trigeminal nerve into the pons. MRI demonstrated the perineural spread, which was confirmed by pathology.
Cavernous Sinus ; Immunocompromised Host ; Infarction ; Magnetic Resonance Imaging ; Mucormycosis* ; Nasal Cavity ; Pathology ; Pons* ; Trigeminal Nerve

Rhinocerebral mucormycosis is a very rare, but mostly fatal fungal infection, usually found in diabetic or other immunocompromised hosts. It has a characteristic pattern of spread, invasion of vessel walls with subsequent local thrombotic infarction or direct invasion. But we found two cases contrast to these typical patterns of spread. Our cases initially originated in the nasal cavity and progressed to the cavernous sinus in usual manner, but after then, extended along the trigeminal nerve into the pons. MRI demonstrated the perineural spread, which was confirmed by pathology.
Cavernous Sinus ; Immunocompromised Host ; Infarction ; Magnetic Resonance Imaging ; Mucormycosis* ; Nasal Cavity ; Pathology ; Pons* ; Trigeminal Nerve

BACKGROUND: Cerebral vasoreactivity (CVR) is known as having insufficient hemodynamic circulation. However, available information for its clinical interpretation is scant. We attempted to find the relationship of CVR with parameters such as stenosis degree and collateral patterns. METHODS: This study was prospectively conducted in 37 patients with more than 50% angiographically proven unilateral carotid stenosis. The relative change of mean flow velocity before and after an acetazolamide challenge was calculated by transcranial Doppler sonography (TCD) and the results were compared with single photon emission computed tomography (SPECT) results. The degree of stenosis and collateral flow patterns were estimated and classified by conventional angiography. RESULTS: The CVR of middle cerebral artery (MCA) was significantly decreased in the ipsilateral side to the carotid stenosis (p<0.05). The CVR impairment was more severe when symptomatic stenosis was present (p=0.04). There was a significant correlation between the degree of carotid stenosis and the CVR (p<0.01). In the area of impaired CVR by SPECT, the estimated CVR was significantly lower (p<0.05), even to the negative value, implying that there is an actually steal phenomenon in that area. CONCLUSIONS: TCD is a useful tool for the assessment of CVR, which can give diverse clinical information based upon the degree of stenosis.
Acetazolamide ; Angiography ; Brain* ; Carotid Stenosis* ; Constriction, Pathologic ; Hemodynamics ; Humans ; Middle Cerebral Artery ; Prospective Studies ; Tomography, Emission-Computed, Single-Photon* ; Ultrasonography, Doppler, Transcranial