A retinal pigment epithelium tumor is extremely rare, and the distinction from malignant melanoma or reactive hyperplasia of pigment epithelium is mandatory, clinically or pathologically. We report a case of adenoma of retinal pigment epithelium. A 21 year-old female presented with a sudden decrease of visual acuity. She had no previous inflammatory ocular disease. Fundic examination revealed an elevated mass at the temporal side of the right eye. With the suspicion of choroidal malignant melanoma, a right eye enucleation was done. Grossly there was a 0.7x0.5 cm dark soft broad-based elevated lesion in the temporal side. The anterior border was the ora serrata, and the posterior border reached the equatorial area. The tumor was confined to the intraocular portion. Histologically, the tumor mass was composed of the cuboidal or columnar cells arranged in papillary, trabecular, or solid pattern with fine fibrovascular stroma. The tumor cells were heavily pigmented. The cytoplasmic border of the tumor cell was indistinct and there was a finely granular brown pigment diffusely scattered in the cytoplasm. Mild anisokaryosis noted, but hyperchromatism or pleomorphism were negligible. The nucleoli were small. A transition between normal retinal pigment epithelium and tumor mass was noted. Reactive gliosis was noted at the periphery of the tumor.
Female ; Humans ; Adenoma

No abstract available.
Urinary Tract Infections* ; Urinary Tract*

No abstract available.
Blood Transfusion* ; Lymphocytes*

No abstract available.
Fetus ; Humans* ; Thymus Gland*

Localized cystic degeneration of peripheral arteries represents and unusual cause of arterial insufficiency. It frequently occurs in patient without generalized arteriosclerosis. It has been reported in patients from age 11 to 62 years. Cystic adventitial disease is most common in the popliteal artery. At least 115 cases have been reported worldwide, but none in Korea. We report a case of cystic adventitial disease involving the left popliteal artery. This 64-year-old man presented with an 18-month history of cramping pain of sudden onset in the left calf and claudication. Angiographic findings showed a 6 cm length of luminal obliteration of the popliteal artery. Segmentally resected popliteal artery showed two longitudinally directed cystic masses measuring 3.5x1.5 cm and 2.5x1.5 cm in the adventitia. Microscopic examination revealed cystic space in the arterial adventitia compressing arterial lumen. There were a number of foamy histiocytes collected along the cystic lumen.
Male ; Humans

A case of pulmonary arteriovenous fistula in a 8-year-old boy who presented with easy fatigability and cyanosis for 4 months, is described. Grossly, there was a large vascular anomaly measuring 2x2 cm in the center of the removed right lower lobe. Microscopically, the lesion consisted of dilated arterial and venous structures resembling a cavernous hemangioma. Subintimal fibrosis and attenuated vascular structure lacking elastic fiber and representing A-V shunt were also noted in the lesion.
Child ; Male ; Female ; Humans

No abstract available.
Aged* ; Erythrocyte Indices* ; Humans ; Korea*

Alveolar soft-part sarcoma of the female genital tract are extremely rare. Fewer than 30 cases have been described in the literature. We experienced a case of alveolar soft-part sarcoma of the female genital tract which was diagnosed by routine light microscopic study using ultrastructural and immunohistochemical stain. We report this case with a brief review of the literature.
Female* ; Humans ; Sarcoma, Alveolar Soft Part*

OBJECTIVE: Flow cytometric deoxyribonucleic acid (DNA) content analysis has been shown to be of prognostic importance in some cancers. In this study, DNA patterns obtained by flow cytometry in patients with cervical cancer have been shown to be related to a prognostic importance in cervical carcinoma. METHODS AND MATERIALS: We retrospectively reviewed 59 cervical cancer patients who admitted to the department of obstetrics and gynecology, Samsung Medical Center firom January 1995 to May 1997. RESULTS: A total of 59 archival paraffin-embedded blocks were proc 42.4 percent were found to be DNA content aneuploid (DNA-A) and 57.6 percent DNA content diploid (DNA-D). The S-phase fraction was significantly increased with stage. The incidences of aneuploid and relative DNA index were not significantly increased with the stage(P=0.280) and age of patients(P=0.088). The results had no significant differences between the squamous cell carcinoma and adenocarcinoma, and no relationship between the groups with keratinizing cell type and nonkeratinizing type(P=0.409). The DNA ploidy patterns were not significantly correlated with metastasis to lymph node(P=0.179), tumor size(P=0.109), invasion depth(P=0.361) and recurrent group(P=0.285). High S-phase fraction had a tendency to correlate with the invasion depth(P=0,011), size(P=0.027), lymph node metastasis(P=0.039) and recurence(P=0.099) of cervical cancer. CONCLUSION: Flow cytometric DNA content analysis is being used more frequently in the management of different malignant tumors. Our study shows that DNA content analysis may not serve as an important biological indicator in determining the prognosis in cervical carcinoma, but High S-phase fraction has been connected with more aggressive tumors.
Adenocarcinoma ; Aneuploidy ; Carcinoma, Squamous Cell ; Cervix Uteri* ; Diploidy ; DNA* ; Female ; Flow Cytometry ; Gynecology ; Humans ; Incidence ; Lymph Nodes ; Neoplasm Metastasis ; Obstetrics ; Ploidies ; Prognosis ; Retrospective Studies ; Uterine Cervical Neoplasms

Glassy cell carcinoma (GCC) of the uterine cervix is a rare and highly malignant tumor, accounting for only 1%~2% of all cervical carcinomas. It is typically composed of malignant cells having a moderate amount of cytoplasm with "ground glass" appearance, distinct cell membranes that stain with eosin or periodic acid-Schiff, and large nuclei with prominent nucleoli. Since its original description in 1956 by Glucletmann and Cherry, 200 - 250 cases of GCC of the uterine cervix have been listed in the literature. We report here the clinicopathological study of one case of glassy cell carcinoma with brief review of the literature.
Cell Membrane ; Cervix Uteri* ; Cytoplasm ; Eosine Yellowish-(YS) ; Female ; Prunus