It has been reported that the Ca2+-ATPase and the Ca2+-Na+exchanger play an important role for the regulation of intracellular Ca2+ in somatic cells, the Ca2+-ATPase located in the plasma membrane helps the Ca2+ concentration in maintain low [Ca2+]i. Roldan & Fleming reported that the spermatozoan Ca2+-ATPase plays an important role in the capacitation and acrosome reaction. We used to assess Ca2+ changes by chlortetracycline (CTC) patterns in the capacitation and acrosome reaction of human and hamster spermatozoa. In the present study applying quercetin which has been known as an ATPase antagonist, the enzymatic effect of Ca2+-ATPase on capacitation and acrosome reaction was found to be remarkable: a significant increase of the transformation from the original type to the B type and the AR type of spermatozoa. This finding suggests that Ca2+-ATPase play an important role in the efflux and the influx of the Ca2+ which have been known to be an essential factor for the capacitation and acrosome reaction, and that the inhibitory action of the Ca2+-ATPase might be a prerequsit step toward the capacitation and acrosome reaction. In conclusion, this study suggest the considerable evidence as follows: the increment of the intracellular Ca2+ concentration occurred by controlling the slope of Ca2+ concentration through Ca2+-ATPase activites in both the intracellular and extracellulr fluid may be important procedures for the capacitation and the acrosome reaction, and finally for fertilization of the sperm and ovum.
Acrosome Reaction* ; Acrosome* ; Adenosine Triphosphatases ; Animals ; Cell Membrane ; Chlortetracycline* ; Cricetinae ; Fertilization ; Fluorescence* ; Humans ; Male ; Ovum ; Quercetin ; Spermatozoa

No abstract available.
Asthma ; Hypersensitivity

No abstract available.
Asthma ; Hypersensitivity

No abstract available.
Erythropoietin* ; Humans ; Kidney Failure, Chronic*

No abstract available.
Urticaria*

No abstract available.
Basophils* ; Histamine Release* ; Histamine*

No abstract available.
Cardiovascular Diseases* ; Smoke* ; Smoking*

From April 1977 to August 1978, author carried out an experiment to detect the presence of trichomoniasis in soldiers. Samples were obtained from 1.293 male soldiers of in-or out-patients of an Armed Forces Medical Center. For detection of Trichomonas vaginalis, both of smear method and culture method were used, and results from two methods were compared. The results were summarized as follows: 1. Detection rate of Trichomonas vaginalis is 1.8% by smear method and 3.1% by culture method respectively. This result showed culture method is about twice as highly detective as smear method. 2. A highest infection rate was found in the 30-40 year group. 3. Most of infected persons showed symptomless, although about 30% of them complained distress such as itching sensation(10%), urethral discharge(7.5), and urinary frequency(7.5%). 4. In the microscopic examination of urine, leukocytes were increased in 65% and epithelial cells were increased in 47.5% among individuals. This result showed there might be infalmmatory changes in about half the positive cases.
Arm ; Epithelial Cells ; Humans ; Leukocytes ; Male ; Military Personnel* ; Outpatients ; Pruritus ; Trichomonas vaginalis

Intraoral Vertical Ramus Osteotomy(IVRO) is a typical osteotomy procedure to setback the mandible for the prognathic patients and has many advantages functionally and morphologically, however, available data to predict the progressive prognosis on the functional rehabilitation of the mandible and the morphological change of the rami of the mandible after IVRO has been less reported. This is a prospective study for the progressive changes on the functional rehabilitation and the morphology of the rami of the mandible after IVRO for the Korean Prognathisms. 38 patients were studied for the functional rehabilitation and 21 patients were for the morphological change. Maxillo-Mandibular Fixation(MMF) was maintained for two weeks after IVRO and active physiotherapy was applied by means of Park's Protocol for next two weeks. Progressive change of the range of motion after release of MMF at maximum mouth opening, protrusion, lateral excursion(right and left) was recorded daily for 15days, and also recorded at 1st, 3rd, 6th, 12th, 18th months on the flow charts in the group for functional rehabilitation study. Nine measurements were measured to check morphological changes of the rami of the mandible at Immediate, 1, 3, 6 and 12 months postoperative period on Panex, P-A and Lateral Cephalometrics. The results were obtained as followings : 1. Mandibular function was returned rapidly during early 5 days after release of MMF, and reached to the almost normal range within 15days. And then slowly and progressively increased more and more afterward. 2. Recovery rate of the mandibular function after IVRO was depended upon the forcible application of a well-oriented protocol for active physiotherapy during early stage(within 15 days) after release of MMF. 3. Evidences of cortex-to-cortex healing between proximal and distal segments of the Mandible(CNS, CA, DOA on Panex) were definitely observed. They were changed slowly from immediate to 3 months but changed remarkably from 3 to 6 months of postoperative period, and then showed continuous but very slow changes afterward. 4. Vertical lengths of the proximal segments(RL, LL) were reduced remarkably from immediate to 3 month of postoperative period, and more slowly reduced from 3 to 6th month period, and then constantly reduced afterward as mimic rate. 5. Transverse distance between proximal segments(TL) was reduced rapidly within one month postoperatively and showed more slow and stable changes until one year follow-up period. 6. The gap between proximal and distal segments was disappeared rapidly within 6 month postoperatively, and then reduced very slowly afterward. 7. The change of Gonial angle(GA) was rapidly increased within one month of postoperative period and then increased very slowly afterward. In summary, mandibular function was returned to almost normal within two weeks after release of MMF, and osseous union was completely established between the proximal and distal segments without any complications in spite of early functional movement of the mandible without fixation between fragments. Morphological changes on the rami of the mandible was remarkable within 3 month period of postoperative and then continuously remodeled until one-year follow-up period. The application of a forcible and well-oriented protocol of active physiotherapy immediate after release of MMF may be the most important factor for prognosis of rehabilitation and morphological changes in IVRO.
Follow-Up Studies ; Humans ; Mandible ; Mouth ; Osteotomy* ; Postoperative Period ; Prognathism* ; Prognosis* ; Prospective Studies ; Range of Motion, Articular ; Reference Values ; Rehabilitation

No abstract available.
Adult* ; Humans