BACKGROUND: Restenosis remains one of major clinical problems in the coronary intervention. The effects of local radiation using radioactive balloon loaded with Ho-166 on coronary restenosis in the porcine model were observed. METHODS: Overdilation injury was performed in porcine coronary arteries using control balloon [Group I, n=, left anterior descending artery (LAD)=, left circumflex artery (LCX)=, right coronary artery (RCA)=] and Ho-166 loaded polyurethane-coating balloon [Group II; n=0, 21.98.1 mCi (20 Gy at 0.5 mm in depth), LAD=, LCX=, RCA=] at 5 atm for 3 min. Follow-up quantitative coronary angiogram (QCA) and histopathologic findings were compared at 4 weeks after balloon injury between two groups. RESULTS: Acute or late thrombotic arterial occlusion was not observed in both groups. Diameter stenosis measured by QCA was not different between two groups (Group I: 11.61.6%, II: 7.68.4%, P=.44). On histopathologic study, injury score, external and internal elastic lamina area, and media area were not different between two groups. Neointimal area and histopathologic area stenosis were significantly higher in Group I (0.320.86mm2, 20.677.01%) than those of Group II (0.150.26mm2, 12.032.44%). By immunocytochemistry, proliferating cell nuclear antigen indices in neointima and media were 8.244.44%, 7.972.46% in Group I, and 7.172.25%, 5.471.44% in Group II, which were not different between two groups(P=.587, 0.089). CONCLUSION: Local radiation using Ho-166 balloon is effective in reducing neointimal proliferation in a porcine model.
Arteries ; Constriction, Pathologic ; Coronary Restenosis* ; Coronary Vessels ; Follow-Up Studies ; Immunohistochemistry ; Neointima ; Proliferating Cell Nuclear Antigen

No abstract available.
Plastics* ; Rhinoplasty*

No abstract available.
Circumcision, Male* ; Female ; Male ; Urinary Tract Infections* ; Urinary Tract*

Childhood UTI is a common bacterial infection in children and frequently associated with urinary tract anomaly and high recurrent rate. Recurrent UTI and even the first UTI, if not diagnosed and untreated, may lead to serious renal scarring, a cause of childhood hypertention and end stage renal failure. It is very important to prevent the sequence of recurrent UTI and the development of renal scarring from the first UTI. However, early diagnosis is very difficult because the symptoms and signs are non-specific in young children and commonly presented with high fever only. In young infants with unexplained high fever, urinalysis and urine culture should be considered for early diagnosis. Emperic antibiotic treatment should be initiated in suspicious UTI and imaging studies of the urinary tract should be performed for the evaluation of urinary tract anomaly and renal scar in confirmed cases of UTI. Antimicrobial prophylaxis has been the common clinical practice in children with high risk factors for recurrent UTI and renal scar. In summary, early diagnosis and proper management of childhood UTI are very important to prevent hypertention and end stage renal disease by renal scar.
Bacterial Infections ; Child ; Cicatrix ; Early Diagnosis ; Fever ; Humans ; Infant ; Kidney Failure, Chronic ; Renal Insufficiency ; Risk Factors ; Urinalysis ; Urinary Tract Infections* ; Urinary Tract*

This study was conducted to investigate the effect of nutrition education on improving dietary attitudes, food habits and Food Frequency of 32 female shift workers by administering questionnaires. Dietary nutrient consumption data were obtained from the female shift workers by using 1 day 24-hr recall. The results were as follows: Score on 'Concerns about health (p < 0.05)' was significantly higher after-training. Dietary attitude (32.3 vs. 34.9, p < 0.01) and food habits (60.2 vs. 67.1, p < 0.01) were significantly higher after thetraining. Scores on 'Eating a lot of food that I want to eat is more important than nutrition (p < 0.01)', 'I have a tendency to use instant foods when I am busy (p < 0.01)', 'I am interested in information on nutrition and health (p < 0.01)' were significantly higher after the training. Scores on 'I have three meals a day (p < 0.001)', 'I have breakfast regularly (p < 0.01)', 'I take vegetables other than kimchi at every meal (p < 0.01)', 'I drink milk every day (p < 0.001)', 'I eat fruits every day (p < 0.01)', and 'I apply nutrition knowledge to daily life (p < 0.001)' were significantly higher after the training. Protein (p < 0.05), fiber (p < 0.05), vitamin C (p < 0.01), and calcium (p < 0.001) intakes were significantly higher after the training. These results showed that nutrition education had improved the dietary attitudes, food habits, and nutrient intakes. Therefore, we conclude that providing more systematic and appropriate nutrition education to shift workers during their tenure of office period is likely to improve dietary attitudes, food habits, and nutrient intakes.
Ascorbic Acid ; Breakfast ; Calcium ; Female ; Food Habits ; Fruit ; Humans ; Meals ; Milk ; Surveys and Questionnaires ; Vegetables

BACKGROUND: During the past half century we have learned much about the functions of the stratum corneum but very little has been proven. Stratum corneum daes not represent the anatomy of this layer in the usual formalira fixed histological preparation. Several techniques have been developed over, the past decades to study the desquamating portion of the humain stratum corneum. There are several methods to measure the serface area of keratinocyte such as a plar,imeter, a graphic tablet and an automatic cytographic counter. OBJECTIVE: The purpose of this study is to find out the accuracy of different measuring devices. METHOD: Standard figures such as a pentagon, a hexagon and a circle, simulating the figure of keratinocyte are used toneasure srea. Repeated measurements of the areas by planimeter, graphic tablet and automatic cytographic counter were analysed by statiatic. RESULT: The planimeter had the advantage of measuring the entire visible area by microscope and a low mean absolute percent error (MAPE) (0.3%), but it needed skill to reduce error and more MAPE (0.5%). Graphic tablet was less time consuming, but had similar advantages of the plarimeter, and needed also skill. On the other hand, the automatic cytographic counter(YK-1) had a very short measuring time and needed less skill, but required good contrast stairing of in order to measure area. CONCLUSION: Comparing the accurracy of three measuring devices of area, the MAPE of the planimeter was 0.3%, the MAPE of YK-1 was 0.5% and the MAPE of graphic tablet was 0.5%.
Hand ; Keratinocytes

No abstract available.
Homeostasis* ; Kidney* ; Sodium*

No abstract available.
Korea*

Nevus lipomatosus superficialis is a rare. disease entity characterized by ectopic dermal fat cells. The lesions are usually either congenital or present by the second decade of life and occur pre-dominantly in the pelvic area. There´are usually no associated abnormalities and familial incidence is not yet reported in English language literature. The authors report a familial case of nevus lipomatosus superficialis with characteristic light and electron microscopic findings.
Adipocytes ; Incidence ; Nevus*

Segmental vitiligo is considered to be characterized by unilateral depigmented patches along dermatomes, but we found two cases of segmental vitiligo in which the vitiligo lesions appeared bilaterally on the same or different dermatomes. The clinical course of bilateral segmental vitiligo seems to be the same as that of unilateral segmental vitiligo.
Vitiligo*