Statisticsl observation was made on 404 patients who had been referred for consultation to the Department of Dermatology during their admission in Seoul National University Children's Hospital from October 1985 to March 1987. The results were as follows : 1. The consulted pstients were 404 among 126,622 inpatients(0.32%). 2. The most frequent age group was below 1 year(25.0%). 3. Pediatrics was the most importnat department in the number, as well as in the rate of consulted patients to inpatients. 4. The most common 10 dermatoses were contact dermatitis, atopic dermatitis, drug eruption, fungal infection, viral infection, infantile eczema, benign tumor, miliaria, urticaria, and skin manifestation of systemic diseases in order of frequency. 5. The frequent causes of consultation were as follows ; the dermatologic diseases or conditions 67.6%, the diseases related to the trestment 13.4%, the skin lesions of systemic diseases 10.8%, the dermatologic tests 3.6%, and admitted to other departments with dermatologic diseases 1.2% respectively.
Dermatitis, Atopic ; Dermatitis, Contact ; Dermatology* ; Drug Eruptions ; Humans ; Inpatients* ; Miliaria ; Pediatrics ; Seoul ; Skin ; Skin Diseases ; Skin Manifestations ; Urticaria

Nevus flammeus is benign but cosmetically devastating congenital vascular malformation whose past treaments have been marred by unacceptable complication or by unacceptable ineffectiveness. Argon laser is a therapeutic device which has been newly applied to this condition with fairly good result. However, all lesions do not show good response and it depends on the clinical and histopathological types. Therefore, it is very important to select patients who will show good response to argon laser therapy. Histological pattern was indicated as the most important prognostic factor. However, it is not always possible to get the histological data. This study was undertaken to evaluate whether it is possible to anticipate histologic patterns of nevus flammeus from color and clinical morphology of the lesions when biopsy is difficult to be taken. Color and clinical morphology of the lesions were recorded, and 4-mm punch biopsies were performed in 74 patients who visited the Laser Clinic in our dermatologic department during past 2 years, The study results were as follows. Eleven pink cases were all patch form morphologically but 8 cases(72, 7%) were constricted type and 8 cases(27 Q%) were intermediate type histopathologically. In 28 red cases, 27 cases(96 4gp) were patch form and only 1 case was smooth elevated form morphologically. And 2p cases(74, l%) were dilated or intermediate type and 7 cases(25 9%) were constricted or deep located type histologically.
Argon ; Biopsy ; Humans ; Laser Therapy ; Nevus* ; Port-Wine Stain* ; Vascular Malformations

No abstract available.
Child* ; Humans

No abstract available.

Nevus flammeus is benign but cosmetically devastating congenital vascular malformation whose past treatments have been marred by unacceptable complication or by unacceptable ineffectiveness. The argon laser is a therapeutic device which has been newly applied to this condition. Blue-green argon light is absorbed by the intraluminal red hemoglobin molecule, leading to the destruction of blood vessels. This study was undertaken to evaluate the therapeutic effect, to look for complications caused by the argon laser on nevus flammeus and to investigate the prognostic values of the color, the degree of blanching and the histological pattern of lesion after laser treatment. All patients were treated with Coherent Radiation Model No. 1,000 Laser with a spot size of 1mm diameter. The power range was 1.8W (irradiance of 229W/cm2), the pulse duration was 0.4 second and the repetition rate was 120 impulses per minute. The result was evaluated according to the criteria of Gilchrest(Table 1). Among the 109 patients who have been treated between November, 1981 and July, 1982 at the Department of Dermatology, Seoul National University Hospital, data from the 49 patients who could be followed up was evaluated and analyzed. (countinued..)
Argon* ; Blood Vessels ; Dermatology ; Humans ; Laser Therapy* ; Nevus* ; Port-Wine Stain* ; Seoul ; Vascular Malformations

No abstract available.
Temporomandibular Joint*

No abstract available.
Urinary Bladder*

The argon laser has been used in the treatment of a variety of cutaneous vascular and pigmented lesions. In 1983, authors reported on the therapeutic effect from argon laser treatment of nevus flammeus. This study was undertaken to evaluate the therapeutic effect and complication of the argon laser on many cutaneous lesions except nevus flammeus. The data of the 67 patients who were treated between November, 1984 and March, 1986 and could be followed up over 3 months at the Department of Dermatology, Seoul National University Hospital were analyzed. Patients were treated with Coherent Radiation Model No. 920 Laser with a spot size of 1 mm in diatemer. The pawer ranges were between 1.6 and 2.6 W using pulsed wave or continuous wave according to the size and the shape of the lesions. The argon laser is an effective modality in the treatment of superficial vascular lesions and especially when telangiectasia is prominent. In pigmented lesions, argon laser is effective for pigmented nevi excluding intradermal nevi and has been found effective in small sized nevus spilus and lentigines.
Argon* ; Dermatology* ; Humans ; Lentigo ; Nevus ; Nevus, Intradermal ; Nevus, Pigmented ; Port-Wine Stain ; Seoul ; Telangiectasis

Streptococcus pyogenes has been regarded very importantly because of its severe sequelae, namely rheumatic fever and acute glomerulonephropathy. Rapid tests to identify this organism have been studied widely in developed countries in 1980s. We proceeded the rapid test (A Strept ADTM, Denka Seiken Co, Japan) of S. pyogenes on 141 children who were Known to be carriers of this organism to evaluate whether the rapid test could be used at the pediatric office base. Throat cultures were taken simultaneously to evaluate the efficacy of this rapid test. The test shoewed very low sensitivity of 17% (13/14) and high specificity of 99% (65/66). The positive predictive value was.93% (13/14) and negative predictive value 51% (65/127) respectively. Most of the positive results of rapid test have been agreed with the actual number of colonies on the throat culture. The reasons for the low sensitivity and negative predictive value of the rapid test should be discovered and supplemented if it could be applicable to the pediatric office and accurate evaluation of the rapid test in patients with acute pharyngitis is needed.
Child ; Developed Countries ; Humans ; Pharyngitis ; Pharynx ; Rheumatic Fever ; Sensitivity and Specificity ; Streptococcus pyogenes* ; Streptococcus*

Allergic contact dermatitis is a prototype of delayed hypersensitivity reaction. Langerhans cells, keratinocytes and T lyrnphocytes play major roles in the pathogenesis of allergic contact dermatitis. We observed Langerhans cells and keratinocytes in contact sensitized epidermal sheets of mice and performed mixed epidermal cell lymphocytes reaction with normal epidermal cells and contact sensitized epidermal cells to determine the lymphocyte stimulating capacity of contact sensitized epidermal cell. We obtained following results : 1. The Langerhans cells were decreased in number and morphologically damaged in contact sensitized epidermis. 2. Ia antigen expression on keratinocytes was detected in almost all contact sensitized epidermal sheets. 3. The allogeneic lymphocyte stimulating capacity of contact sensitized epidermal cells was greater than that of normal epidermal cells. 4. The allogeneic lymphocyte stimulating capacity of contact sensitized epiderrnal cells was lost after treatment of epidermal cells with anti Ia antibody and complement. From these results, it is conceivable that the contact sensitized epidermal cells can amplify the immune reactions by stimulating the lynphocytes which are infiltrated in contact sensitized epidermis.
Animals ; Complement System Proteins ; Dermatitis, Allergic Contact ; Epidermis ; Histocompatibility Antigens Class II ; Hypersensitivity, Delayed ; Keratinocytes ; Langerhans Cells ; Lymphocytes ; Mice*