Experimental hydronephrosis was induced in rabbit by ureteral ligation, then deligation followed after certain experimental period as designed. Histopathological changes of the kidney and restoration of hydronephrosis were studied and the following results were obtained: 1. Ligation of the ureter for 3 days produced mild to moderate degrees of tubular dilatation. irregular proliferation and dilatation of small arterioles. Deligation initiates regeneration of the tubules at 1 week and almost normal histology returns by 3 weeks. 2. Ligation of the ureter for 5,7 and 14 days causes marked tubular dilatation, atrophy of the .cortex, and partial obliteration of the glomerulus. By 3 weeks after deligation, the tubules seem to partially regenerate but no significant histological changes were observed. 3. Ligation of the ureter for 21 to 60 days causes formation of scar, marked obliteration of the glomerulus and compensatory hypertrophy of the remaining glomerulus. No morphological restoration was observed by 3 weeks after deligation. 4. It seems that histological restoration starts at periglomerular tubules located closer to the cortex toward the medulla.
Arterioles ; Atrophy ; Cicatrix ; Dilatation ; Hydronephrosis* ; Hypertrophy ; Kidney* ; Ligation* ; Regeneration ; Ureter*

No abstract available.
Tooth, Artificial*

BACKGROUND: Few studies have demonstrated an enhanced skin responsiveness to opiates in atopic subjects. OBJECTIVE: To determine whether the skin response to morphine is increased in atopics and to assess the clinical usefulness of morphine skin prick test in diagnosis of allergic diseases. METHOD: Allergy skin prick tests were performed using 55 common allergens, histamine, and morphine in 158 patients with allergic diseases. RESULTS: Wheal and flare sizes for morphine (1mg/mL) were significantly related to and smaller than those for histamine (1mg/mL). Although the proportion of subjects with allergic rhinitis and the level of serum total IgE were not different between responders (wheal >- 2mm) and nonresponders to morphine, the positive response rate to allergens was significantly lower in nonresponders. The flare sizes for morphine were significantly higher in positive allergen test group (A/H ratio >- 0.5). Among positive allergen test group, the subjects with atopy score >- 5 showed a larger flare size for morphine than those with atopy score < 5 while the sizes for histamine were not different. CONCLUSION: Morphine skin prick test is helpful for detecting false negative responses to allergens, and morphine skin test responses are increased in highly atopic patients probably due to enhanced mast cell releasability.
Allergens ; Diagnosis* ; Histamine ; Humans ; Hypersensitivity ; Immunoglobulin E ; Mast Cells ; Morphine* ; Rhinitis ; Skin Tests ; Skin*

No abstract available.
Yersinia enterocolitica* ; Yersinia*

BACKGROUND: Wheezing which is defined as a continuous sound with a musical quality is commonly auscultated in patients with chronic obstructive airway diseases. The correlation between wheezing and airway obstruction is unclear. OBJECTIVE: This study was designed to evaluate the relationships among wheezing, severity of airway obstruction, and pulmonary function tests. METHOD: Forty-one subjects were examined by the same observer. Wheezing during normal breathing and maximal forced exhalation, was auscultated respectively. Posterior lung bases were auscultated bilaterally with the seated patient taking repeated inspiratory capacity breaths through an open mouth. To quantify wheezing intensity, a regional score was assigned for each area after a minimum of 3 breaths, according to the following scale: zero, no wheezing heard: one, faint or intermittent wheezes: two, moderate wheezing during every expiration: three, loud wheezing during every expiration. The lung function tests by standard pneumotachograph were performed by skilled technicians. RESULTS: Wheezing was auscultated more in forced exhalation than in normal breathing in patients with asthma and COPD [8/9(88%) vs 1/9(11%), p<0.01 ll/15(73%) vs 1/15(6%), p<0.05)]. Forced expiratory wheezes group (n=25) compared to no wheezes group (n=16) had significantly lower FEVl (75+-5.8% vs 95.6+-6.6%, p<0.05). Compared to no wheezes group, the group with forced expiratory wheezes had lower FEV1 and FEV1/FVC (50.4+- 21.3% vs 81.15+-27.7%, 70.4+-22.4% vs 92.5+-19.3%, respectively, p<0.05). Bronchial asthma compared with COPD tended to have higher wheezing scores (Wheeze scores Bronchial asthma 3.5 vs COPD 2.4, p=0.08). Wheezing scores were correlated to FEV1 (normal breathing: r=-0.35, p<0.05: forced exhalation: r=-0.45, p<0.05), but no differences were found in wheezing incidence according to severity of airway obstruction. CONCLUSION: These findings suggest that wheezing on maximal forced exhalation may be a useful physical indicator for evaluating the severity of airway obstruction.
Airway Obstruction ; Asthma ; Exhalation ; Humans ; Incidence ; Inspiratory Capacity ; Lung ; Mouth ; Music ; Pulmonary Disease, Chronic Obstructive* ; Respiration ; Respiratory Function Tests ; Respiratory Sounds*

With the wide spread of laparoscopic procedures in surgery, laparoscopy has been revived as a diagnostic and therapeutic modality in blunt and penetrating abdominal trauma. From August 1995 to November 1996, we applied therapeutic laparoscopy to 15 hemodynamically stable patients with abdominal trauma, including 10 (66%) blunt and 5 (34%) penetrating injuries. The mean age of the patients was 35 (17~64) years. All were male, except for one female patient. Organs injured were 4 single perforations, 1 multiple perforation and 1 complete transsection of the small bowel; 2 mesenteric tearings with small bowel ischemia; 2 stomach perforations; 2 mesenteric lacerations; 2 omental lacerations; and 1 liver laceration. Patients with unstable vital signs, or solid organ or retroperitoneal injury were excluded by conventional diagnoses. Laparoscopic abdominal exploration was initiated by changing the position to the Trendelenburg position for evaluation of the pelvic cavity and lower-1/3 of the small bowel, to the supine position for evaluation of the mid-abdomen and mid-1/3 of the small bowel, and to the reverse Trendelenburg for evaluation of the liver, spleen, pancreas, and upper 1/3 of the small bowel. Operation methods consisted of totally laparoscopic or laparoscopic-assisted techniques in 11 cases (73.3%) and 4 cases (26.7%), respectively. Hence, we were able to reduce the rate of open surgery in 11 (73.3%) of the 15 patients who were thought to need operative treatment, 14 of whom needed actual surgical intervention (One pre-operatively undetected liver laceration revealed spontaneous ceasation of bleeding at the time of laparoscopic examination). The mean operation time was 110 min per case (113 min and 100 min for totally laparoscopic surgery and laparoscopic-assisted surgery, respectively). Flatus passed at the 2.4 (mean) post-operative day. The patients started meals at the 3.3 (mean) post-operative day and were discharged at the 7 (mean) post-operative day uneventfully. The only exception was one wound infection in the laparoscopic-assisted group. Conclusively, sytematized laparoscopic surgery is a feasible, safe, and effective procedure for the treatment of abdominal trauma.
Diagnosis ; Female ; Flatulence ; Head-Down Tilt ; Hemorrhage ; Humans ; Ischemia ; Lacerations ; Laparoscopy* ; Liver ; Male ; Meals ; Pancreas ; Spleen ; Stomach ; Supine Position ; Vital Signs ; Wound Infection

There are many established roentgen signs of ascites such as hepatic angle sign, generalized graying of the abdomen, frog belly appearance and Hellmer's sign. These signs are easily recognized in the standard flat abdomen film. It is however hardly possible to recognize such signs in small films of double contrasted upper GI series. By a retrospectroscopical observation we were able to find some interesting signs of massive ascites in small size films of double contrasted stomach and duodenum of upper GI series. The clinical materials consisted of 27patients with massive ascites and 30 normal subjects. The signs we observed were ;(1) Constriction deformity of the junction of the fundus and body of the stomach. We named this "waist" sign. This constriction was attended by convergence of mucosal folds. We called this "converging folds" sign. (2) The fundus assumed electric bulbappearance with its long axis directed vertically. We called this "electric bulb" sign. In normal subjects the fundus assumed beret-cap like appearance. These signs were only appreciated in the supine and RAO views and not in other views. Of these new signs of massive ascites where fundic view was obtained in supine or RAO position.
Abdomen ; Ascites ; Congenital Abnormalities ; Constriction ; Duodenum ; Stomach

Helicobacter pylori (H. pylori) has been recognized as a main cause of gastritis and most cases of peptic ulcer, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. An immunological response to H. pylori infection has been suggested to play a major role in determining gastroduodenal damage through the production of cytokines and the autoantibody against gastric epithelial cell. H. pylori has been implicated in the pathogenesis of some autoimmune disease, such as Sjogren disease, Henoch-Schnlein purpura, rheumatoid arthritis, autoimmune thyroid disease, and idiopathic thrombocytopenic purpura (ITP). Serveral studies recently showed a high prevalence of H. pylori infection in patients with ITP and reported a platelet recovery after bacterial eradication therapy. We report a case of a 54-year-old man with chronic ITP who was resolved after eradication of H. pylori.
Adenocarcinoma ; Arthritis ; Autoimmune Diseases ; Blood Platelets ; Cytokines ; Epithelial Cells ; Gastritis ; Helicobacter pylori* ; Helicobacter* ; Humans ; Lymphoma, B-Cell, Marginal Zone ; Middle Aged ; Peptic Ulcer ; Prevalence ; Purpura, Schoenlein-Henoch ; Purpura, Thrombocytopenic, Idiopathic* ; Thyroid Diseases

No abstract available.
Asthma*

No abstract available.
Animals ; Cattle* ; Yersinia enterocolitica* ; Yersinia*