Sexual function is and important component of an individual's quality of life and subjective well being. In the field of erectile dysfunction (ED), we have witnessed the introduction of truly effective oral pharmacotherapy for this disorder. The marketing of the first oral phosphodiesterase (PDE) inhibitor (sildenafil, viagra®) in 1998 increased the public's awareness about sexual dysfunction and enlightened their perceptions about ED as a medical condition with distinct risc factors. Sildenafil has shown excellent effects in the treatment of ED patients with or without cardiovascular disease although the agent is contraindicated in patients taking nitrates. Sublingual (SL) apomorphine (uprima®) is a nonopioid, centrally acting dopamine agonist developed to treat ED. Three milligrams of SL apomorphine SL 3㎎ has significant benefit for men with ED as measured by all currently acceptable erectile function endpoints of 'erections firm enough for intercourse'. Self-injection therapy (alprostadil, caverject® or trimix) is a very effective treatment option. In a short time, multiple agents (vardenafil, tadanafil, et al.) will be developed and introduced for management of ED. The impending approval of new treatment for ED will bring a plethora of choices for the physician treating ED. Primary care physicians will look to urologists as the experts in ED for information and guidance on which medication to use. It is therefore important that we keep abreast of developments in this rapidly evolving field of sexual medicine.
Apomorphine ; Cardiovascular Diseases ; Dopamine Agonists ; Drug Therapy ; Erectile Dysfunction* ; Humans ; Male ; Marketing ; Nitrates ; Physicians, Primary Care ; Quality of Life ; Sildenafil Citrate

No abstract available.
Humans ; Prostatitis*

No abstract available.
Clone Cells* ; Humans*

Electrical burns constitude a unique type of thermal injury. Not only may there be a cutaneous burn but frequently hidden local and regional tissue damage exists. Tissue injury and tenden vascular necrosis are complete within eight to ten days follwoing the insult and additional tissue damage can occur because of infection and toxicity of necrotic tissue. Early excision and early graft can prevent this progressiv muscle necrosis because marginally viable tissue at the periphery are saved by the increased vascularity provided by immediate use of flaps or grafting. We have treated 67 cases of electrical burn from 1975 to 1979. The brief summary of the observations were as follows: 1. Good results were obtained in 15 cases after treatment of early excision and early graft. 2. Simultaneous involvements of hand, wrist, elbow, and shoulder were found because of tetanic contraction in alternating current in 21 cases. 3. In one case of spinal atrophic paralysis due to direct injury to spinal cord, paraplegia was permanent.
Burns ; Clinical Study ; Elbow ; Hand ; Necrosis ; Paralysis ; Paraplegia ; Shoulder ; Spinal Cord ; Transplants ; Wrist

We report five cases of solitary mastocytoma. All patients were under one year of age and diagnosed as solitary mastocytoma based on clinicopathologic findings. Skin lesions were found on the right forearm, left hand, left leg, left elbow and left shoulder. They resolved themselves spontaneously resolution within 2 or 3 years.
Elbow ; Forearm ; Hand ; Humans ; Leg ; Mastocytoma* ; Shoulder ; Skin

To define the effectiveness of surgical management of the mallet finger deformity due to extensor tendon injury in children, we analyzed 9 patients who had operative treatment of mallet finger deformity in children from Jan. 1994 to Mar. 1997. The types of tendon injury in this series were as follows: 7 cases with tendon laceration, 1 case with crushing injury and 1 case with unknown injury The average period of follow up were ranged 2 years and 1 month. The clinical results were evaluated hy Kanies seale12) and Crawford scale5). An excellent result was obtained in 4 cases(44%), a good result in 5 cases(56%) according to Crawford scale and excellnt result in 9 cases(I00%) in Kanies scale, consecutively. Meticulous surgical repair of the lacerated tendon provided good result.
Child* ; Congenital Abnormalities* ; Fingers* ; Follow-Up Studies ; Humans ; Lacerations ; Tendon Injuries* ; Tendons*

A large mass as a sign of an infection is rare, and it might convince a physician that it had the appearance of a malignancy. The patient in this case visited our clinics after attending several hospitals, with a mass that had the appearance of a malignancy, based on the severe destructive findings observed on plain radiographs. We report the first documented case of a patient with a large mass (12×7×20 cm) and a low-grade infection, which developed at the proximal thigh after a hip arthroplasty. It is important to realize that an infection accompanied by a large mass, can mimic a highly destructive malignant lesion on plain radiographs.
Arthroplasty* ; Hip* ; Humans ; Thigh*

No abstract available.
Hip

From March 1973 to May 1979 at Hanil Hospital, seven patients with acute complete disiocation and three patients with chronic complete dislocation of the acromloelavlcular Joint had been treated surgically by Weaver and Dunn method which combines resection arthroplasty of the acromioclavicular jolnt with flxation of the clavlcle In an anatomical position by suture of the acromial end of the shortened coracoacromial ligament into the medullary canal of the clavicle. The results were considerably good In both acute and chronic cases. Full range of motion was observed on average In eight weeks in most cases.
Acromioclavicular Joint ; Arthroplasty ; Clavicle ; Dislocations ; Humans ; Joints ; Ligaments ; Methods ; Range of Motion, Articular ; Sutures

Bleomycin is an antitumoral antibiotic derived from Streptomyces verticillus in 1965. The drug has been used with a varying success in the treatment of squamous cell carcinomas and malignant lymphomas. The cutaneous toxicities of bleomycin include hyperpigmentation, sclerosis, gangrene, nail changes and erythema. Linear streaks appear to be a characteristic eruption induced by bleomycin. We report three cases of flagellate pigmentation from intravenous bleomycin. Three patients were suffering from uterine cervical carcinomas and were treated with chemotherapy with a VBP (vincristine, bleomycin, cisplatire) regimen. During or after their courses of chemotherapy, dark brownish skin lesions developed on the body surface of these patients. A Light microscopic study of each specimen showed increased pigmentation of the basal layer and an electron microscopic study showed a slightly increased number of melanosomes in keratinocytes.
Bleomycin* ; Carcinoma, Squamous Cell ; Drug Therapy ; Erythema ; Gangrene ; Humans ; Hyperpigmentation ; Keratinocytes ; Lymphoma ; Melanosomes ; Pigmentation* ; Sclerosis ; Skin ; Streptomyces