No abstract available.
Rectal Prolapse*

Twenty five patients with moderate to severe anal stenosis were treated with sliding skin graft during the period of time from April 1987 to March 1996. And a follow-up study was carried out on 18 cases among them. The original causes of the anal stenosis were previous necrotherapy in 14, hemouhoidectomy in 3, and cryotherapy in one. Postoperatively, partial disruption of the suture line developed in 2 cases and perianal fistula in one. Long term clinical results were good in 12 cases, fair in 4, and poor in 2. As a result, sliding skin graft is thought to be a simple and effective method for the treatment of moderate to severe anal stenosis.
Constriction, Pathologic* ; Cryotherapy ; Fistula ; Follow-Up Studies ; Humans ; Skin* ; Sutures ; Transplants*

No abstract available.

A myolipoma is an extremely rare benign neoplasm, occurring most frequently in adults in the deep soft tissue of the abdomen or retroperitoneum. We experienced a case of an anal myolipoma occurring in a 30-year-old woman, and it was surgically resected. To our knowledge, this is the first reported case of a myolipoma arising from the anus, so such a possibility needs to be considered in the differential diagnosis.
Abdomen ; Adult ; Anal Canal ; Angiomyolipoma ; Diagnosis, Differential ; Female ; Humans

No abstract available.
Child* ; Humans ; Mycoplasma pneumoniae* ; Mycoplasma* ; Pneumonia* ; Pneumonia, Mycoplasma*

Vogt-Koyanagi-Harada syndrome is characterized by bilateral uveitis, alopecia, poliosis, dysacousia, and sings of meningeal irritation. Vogt-Koyanagi syndrome is a severe anterior uveitis associated with alopecia, vitiligo, poliosis, and dysacousia. On the other hand, Harada's disease is primarily a posterior uveitis accompanied by sings of meningeal irritation and abnormalities of cerebrospinal fluid. The overlapping of clinical manifestations between two entities have justified as part of a spectrum of one disease. The etiology is not clearly determined but two most reliable theories as to the cause of the Vogt-Koyanagi-Harada syndrome have been considered as allergic reaction to the uveal pigment or viral infection. The authors experienced a 27-year-old Korean male who had acute bilateral uveitis, headache, dysacousia, alopecia, poliosis, vitiligo on the back, and retinal pigment epithelial detachment of posterior pole in the fluorescein angiography. Thus the authors present this case with clinical manifestations, fluorescein angiographic findings. our schedule of steroid therapy, and review of literatures.
Adult ; Alopecia ; Appointments and Schedules ; Cerebrospinal Fluid ; Fluorescein ; Fluorescein Angiography ; Hand ; Headache ; Humans ; Hypersensitivity ; Male ; Retinal Detachment ; Uveitis ; Uveitis, Anterior ; Uveitis, Posterior ; Uveomeningoencephalitic Syndrome* ; Vitiligo

No abstract available.
Endocrine Cells* ; Gastrointestinal Tract* ; Goats*

Cyanosis in children is most often caused by pulmonary disease, or cyanotic heart disease but is rarely caused by hematological problems such as methemoglobinemia and sulfhemoglobinemia. Abnormal hemoglobins with a reduced oxygen affinity are an exceptionally uncommon cause of cyanosis in children. Hemoglobin-M (Hb-M) is rapidly auto-oxidized into the met-form resulting in the loss of its O2-binding ability. This hemoglobinopathy is inherited in an autosomal dominant pattern and is characterized by marked cyanosis. Hb-M affects the anesthetic management because of the anomalous absorption spectrum of Hb-M in standard pulse oximetry. Sufficient O2 delivery should be maintained by keeping a high FiO2 and intermittently checking the O2 delivery state using arterial blood gas analysis. We reported our experience of the anesthetic management of a patient with hemoglobin M.
Absorption ; Blood Gas Analysis ; Child ; Cyanosis ; Heart Diseases ; Hemoglobin M ; Hemoglobinopathies ; Hemoglobins, Abnormal ; Humans ; Lung Diseases ; Methemoglobin ; Methemoglobinemia ; Oximetry ; Oxygen ; Sulfhemoglobinemia

Phospholipase C (PLC) plays a pivotal role in transmembrane signal transduction pathway for cellular proliferation differentiation and growth. Thus far, there have been few reports in which PLC activity was investigated in human malignant neoplastic tissues. In the present study, we evaluated PLC activity in 23 human gastric cancer tissues and normal mucosal tissues to investigate whether alteration of PLC activity is associated with gastric cancer. The amount of [14C] diacylglycerol, one of the earliest products of inositol phospholipid hydrolysis by PLC, was measured by thin layer chromatography. Also, expression of PLC-gamma1, which is one of the most important PLC isozymes,was examined by immunohistochemistry using specific monoclonal antibody directed against PLC-gamma1. The results are summarized as follows. PLC activity in all 23 gastric cancer tissues (1.35+/-1.04 units/mg of protein) was significantly higher than normal mucosal tissues (0.28+/-0.21 units/mg of protein) (P<0.001). PLC activity in gastric cancer tissues was not correlated with histologic grade (P>0.05). PLC-gamma1 immunoreactivity was detected in all of 23 cases studied. The intensity and extent of PLC-gamma1 immunoreactivity was not correlated with PLC enzyme activity, although stronger intensity was demonstrated in malignant cells in comparison to normal gland epithelial cells. The present study provides the first evidence of significant elevation of PLC activity in human stomach cancer tissues. Our results strongly suggest that PLC might be involved in tumorigenesis and/or progression(uncontrolled continuous cycling of cells) of human gastric cancer. Further studies are needed to elucidate the role of elevated PLC activity in cancer tissues.
Humans ; Cell Transformation, Neoplastic ; Stomach Neoplasms

The authors compared the basic characteristics of rural woman in relation to family planning for June 1967 and June 1969 in Kyung San Country Kyungpook Province, Korea. The statistics showed that these characteristics are gradually changing. The marriage age was slightly higher than the past year and the formal education of women increased. The ideal children number, and tile gravidity and mortality rates decreased. At the same time the number of induced abortions, the knowledge of family planning, and the acceptance rate of contraception increased. These phenomena seem to follow the present worldwide trend.
Abortion, Induced ; Child ; Contraception ; Education ; Family Planning Services* ; Female ; Gravidity ; Gyeongsangbuk-do ; Humans ; Korea ; Marriage ; Mortality