No abstract available.
Adult* ; Cytomegalovirus* ; Fluorescent Antibody Technique* ; Humans*

No abstract available.
Adult* ; Cytomegalovirus* ; Fluorescent Antibody Technique* ; Humans*

BACKGROUND: The population is aging and life expectancy is increasing. It is important to evaluate the functional ability of elderly for optimal care for elderly. This study was conducted to assess functional disability of elderly and to find out the factors having an effect on the disability. METHODS: It surveyed 1,541 individuals aged 65 years and older in Cluing-Yang province. Six ADL categories (bathing, dressing, feeding, transferring, toileting, and walking) were assessed and related factors were analyzed. RESULTS: ADL was independent in 85.2% of elderly and dependent in 14.8% of elderly. 55.1% of dependent elders were living without family. Bathing was the most common disable AI)L category. The factors having an effect on the disability of ADL were brain disease, self-rated health status, dyspnea, constipation, heart disease, diabetic mellitus, and living status. CONCLUSION: In a rural area, special prevention programs for brain disease, heart disease, and diabetic mellitus and a rehabilitation health service may improve ADL status of elders.
Activities of Daily Living* ; Aged* ; Aging ; Bandages ; Baths ; Brain Diseases ; Constipation ; Dyspnea ; Health Services ; Heart Diseases ; Humans ; Life Expectancy ; Rehabilitation

No abstract available.
Nephrotic Syndrome* ; T-Lymphocyte Subsets* ; T-Lymphocytes*

Recently, it was revealed that Jong-Ha Kim was the first self-employed Korean physician in Daejeon city of South Korea during the Japanese colonial period. However, little is known about him. In this paper, the author aimed to search for historical records of his activities as the first Korean physician in Daejeon city.Current Concepts: Kim’s clinic in Daejeon city was called Chung-Ang Clinic. This is all that has ever been confirmed about Jong-Ha Kim. The author has been searching for his medical record for the last year. Kim’s medical records were collected from journal papers on the modern history of Korea, National Institute of Korean History database, Naver news library archive, official gazette of the Japanese government-general of Korea, database of Seoul National University alumni, and a resume of a professor at the Hamhung Medical School. The results are as follows. He was born in Shinchang-ri Hamheung city Hamgyeongnam-do on August 9, 1900. He graduated from the missionary school established by Canadian missionaries and was admitted to Kyungseong (Keijo) Medical School in 1918. It was recently discovered that he participated in the Independence movement on March 1, 1919. His picture, an old leaflet for his clinic which he had used, and his resume as a professor at the Hamhung Medical School were discovered for the first time.Discussion and Conclusion: The historical records of Jong-Ha Kim’s life provide insight into the lives of contemporary doctors in modern Korea. During the period of 1900 to 1950, which encompasses his historical records, significant events took place in Korean history, and he actively participated in these events. Despite facing numerous difficulties as a doctor in modern Korea, Jong-Ha Kim made decisions that had a great impact. He was a great doctor who served as a good role model.

No abstract available.
Adenocarcinoma*

In this study, the feasibility of identification and genotypic differentiation of enteroviruses was investigated by using nested reverse transcription-polymerase chain reaction (nested RT-PCR), single-stranded conformation polymorphism (SSCP), and restriction fragment length polymorphism (RFLP) techniques. Two hundred seventy-four clinical samples were assayed by both nested RT-PCR and tube culture method using MRC-5 and MK cells; 58 (86.6%) out of 67 enterovirus culture-positive samples contained enteroviral RNA. In addition, 114 (55.1%) of 207 samples from patients with suspected enteroviral CNS disease with negative viral cultures were positive by the nested RT-PCR. The nested RT-PCR products were genotyped by the SSCP method and the results were compared with serotypes. We could differentiate 6 subtypes, 3 of which are similar to coxsackievirus B3, B5, echovirus 11, plus 3 other subtypes. RFLP cleaved with Sty I, Bgl I, and Xmn I yielded characteristic patterns for each laboratory strains. This study demonstrates the usefulness of the RT-PCR for the rapid diagnosis of enterovirus infection and the potentials of the SSCP method for differentiation of enterovirus strains.
Central Nervous System Diseases ; Diagnosis ; Enterovirus B, Human ; Enterovirus Infections ; Enterovirus* ; Genotype* ; Humans ; Polymorphism, Restriction Fragment Length ; Polymorphism, Single-Stranded Conformational ; RNA

Physiotherapy, psychotherapy, hormone therapy, chemical therapy, traditional surgical methods; amputation of painful extremities, cordotomy, leucotomy, rhizotomy, electrode insertion into the dorsal column of cord and acupuncture have been performed for therapeutic approaches to pain relief, but still there are problems in management of complete relief for the chronic pain today. At present, another new method of eliminating chronic pain is based on expanding the neurophysiologic aspect. Among the above mentioned therapeutic approaches to chronic pain relief, spinal barbotage seems to be least stressful to the patient and very effective in some cases. We have experienced a case of successful control of chronic pain by spinal barbotage for a 62 year old woman with metastatic colon carcinoma. The patient was well controlled chronic pain for 28 hours after the first spinal barbotage and for 3 weeks after the second spinal barbotage. It is considered that spinal barbotage is more simple, convenient and effective than other methods for intractable pain relief.
Acupuncture ; Amputation ; Chronic Pain ; Colon ; Cordotomy ; Electrodes ; Extremities ; Female ; Humans ; Middle Aged ; Pain, Intractable* ; Psychosurgery ; Psychotherapy ; Rhizotomy

We report a case of hepatoma with duodenal metastasis in a 53 year-old male patient. Hepatoma was confirmed by fine needle aspiration cytology technique, and duodenal metastasis by gastrofiberscopic biopsy. Duodenal metastasis of hepatoma is rare. We briefly review the role of fine needle aspiration cytology technique in diagnosis of hepatoma.
Biopsy ; Biopsy, Fine-Needle ; Carcinoma, Hepatocellular ; Child* ; Diagnosis ; Endodermal Sinus Tumor ; Humans ; Male ; Mediastinum ; Middle Aged ; Neoplasm Metastasis ; Proteinuria* ; Specific Gravity*

Human immunodeficiency virus type 1 (HIV-1) phenotype plays an important role in the pathogenesis of AIDS. The presence of syncytium-inducing (SI) HIV-1 isolates in infected persons is associated with a rapid decline of CD4+T cells (CD4+), rapid disease progression, and reduced survival time after AIDS diagnosis. We have reported the effects of Korean red ginseng (KRG) on HIV-1 infected patients. To investigate whether KRG affects HIV-1 at gene level and there is a correlation between genotype and decline of CD4+, the C2-V3 region of env gene from 65 HIV-1 isolates were cloned and sequenced. Distributions of subtype were subtype B 57 (88%), subtype A 4 (6%), subtype C 2 (3%), subtype G 1 (2%), and subtype H 1 (2%). The prevalences of SI according to the number of CD4+ are as follows; 40% (6/15) in CD4+ <100/ ul, 14% (1/7) in 100-200/ul, and 2% (1/43) in >200/ul. Seventy-five percent (6/8) of SI were detected in rapid progressor with the decline of CD4+ over 60/ul per year. The correlation between SI genotype and the detection of immune complex dissociated (ICD) p24 antigen was significant (p<0.001). In the 40 patients followed-up over 60 months by CD4+, there was significant correlation between annual decrease of CD4+ and duration of KRG intake (R=-0.380, p<0.01), whereas no correlation between CD4+ and zidovudine (ZDV) was observed. The intrapatient variation of amino acid level showed significant inverse correlation with the months of KRG intake (R=-0.47, p<0.01). These results suggest that the determination of genotype by C2- V3 sequencing may be used for the evaluation of prognosis of AIDS patient, and long-term intake of KRG may prevent or delay the progression from NSI to SI.
Antigen-Antibody Complex ; Clone Cells ; Diagnosis ; Disease Progression ; Genes, env* ; Genotype ; HIV* ; HIV-1* ; Humans* ; Panax* ; Phenotype ; Prevalence ; Prognosis ; Sequence Analysis* ; Zidovudine