No abstract available.
Diphyllobothrium*

PURPOSE: To analyze the variable MRI features and clinical significance of intracranial cavernous realformation. MATERIALS AND METHODS: Forty patients(mean age 35.4) with cavernous malformation were evaluated by MRI. Eleven patients were surgically confirmed. Cavernous malformations were divided into four categories on the basis of the MR imaging characteristics, especially on T2-weighted image. Type I lesion was defined as an extralesional subacute hemorrhage outside the low signal rim, type II as an intralesional hemorrhage surrounded by low signal rim, type III lesion as an intralesional thrombosis with variegated central core surrounded by low signal rim, and type IV lesion as a focal old hemorrhagic core with small low signal intensity. Type IV was further divided into IVa and IVb, whether the lesion has small iso- or hypersignal central core (IVa) or not (IVb). Follow-up MRI was evaluated in 12 patients who were managed conservatively. Follow-up intervals ranged from 2 weeks to 29 months (mean 6months). RESULTS: Total 80 lesions were detected in 40 patients. Multiple lesions were noted in 10 patients. The topography of the cavernous malformations was supratentorial in 75% and infratentorial in 23%. There were 10 lesions in type I, 15 in type 11, 21 in type III, 14 in type IVa, and 20 in type IVb. Type I lesions mainly showed mass effect and edema. Type III lesions showed minimal contrast enhancements in 7 lesions on delayed images. Type II lesions showed the characteristics of both type I and type III lesions. On follow up images, decrease in size in 5, change of type in 7, rebleeding in 2 and no change in 12 lesions were demonstrated. Hemorrhage, edema and mass effect were combined in the cases of rebleeding. On follow-up study, the estimated risk of bleeding was 32.3%/person-year and 13.7%/lesion-year. CONCLUSION: Cavernous realformations show as variable appearance, on MR imaging suggesting variable stages of evolution. The MR morphologic classification and evaluation of secondary findings are helpful to predict natural course and possibility of rebleeding of the lesion.
Classification ; Edema ; Follow-Up Studies ; Hemorrhage ; Humans ; Magnetic Resonance Imaging* ; Thrombosis

No abstract available.
Pancreaticoduodenectomy*

It is well known that metastatic bone tumor is very rare below knee and elbow joint. Recently, we experienced two cases of metastatic tumor from kidney and lung to the tibia at Koryo General Hospital.
Elbow Joint ; Hospitals, General ; Kidney ; Knee ; Lung ; Tibia

The authors describe a case of pituitary tuberculoma in 45 year old female patient with previous history of tuberculous meningitis. Her clinical complaints were headache, visual field defects and amenorrhea. Endocrinological studies showed hypopitutitarism. Radiological studies including CT showed tumor mass in the sella turcica and suprasella area & paietal lobe. Ramamurthi and Varadarajan described the two types of the intracranial tuberculoma ; 1) A superficial and vascular type requires operation only in selected cases and it responds favoratly to treatment. 2) A deep and avascular type accompanied by increased intracranial tension and a spaecoccupying lesion, which does not respond to medical treatment and requires operation. Removal of the pituitary tuberculoma by T.S.A. followed by antituberculous treatment resulted in resolution of her neurological symptoms and signs.
Amenorrhea ; Female ; Headache ; Humans ; Middle Aged ; Sella Turcica ; Tuberculoma* ; Tuberculoma, Intracranial ; Tuberculosis, Meningeal ; Visual Fields

No abstract available.
Korea* ; Lung Neoplasms* ; Lung*

Visual acuity refers to the spatial limit of visual discrimination. It is surely the single most significant measure of functional integrity of the eye. Normal visual acuity can be represented in hyperopia of less than 2 diopters or astigmatism of less than 1 diopter. The purpose of this study was to observe the prevalence, type and degree of of refractive errors in 338 eyes of 40-69 years of age with normal visual acuity(20/20 or more). The results were as follows: 1. In objective manifest refraction, 246 eyes(72.8%) had refractive error such as hyperopia(110 eyes), simple hyperopic astgmatism(61 eyes),compound hyperopic astigmatism(57 eyes) and simple myopic astigmatism(18 eyes). 2. In subjective manifest refraction, 132 eyes(39.1%) had refractive error such as hyperopia(51 eyes), simple hyperopic astigmatism(44 eyes), simple myopic astigmatism(24 eyes) and compound hyperopic astigmatism(13 eyes). 3. As to the type of astigmatism, 71 of 81 astigmatism were "against the rule" and the rest(10 eyes) "with the rule". Degree of astigmatism was less than 1.00 diopter. 4. A verage degree of refractive errors was 0.43 diopter.
Adult* ; Astigmatism ; Discrimination (Psychology) ; Humans ; Hyperopia ; Prevalence ; Refractive Errors ; Visual Acuity*

No abstract available.
Breast Neoplasms* ; Breast* ; Estrogens* ; Humans*

The effect of a secretory proteinase from the pathogenic amoebae Acanthamoeba castellanii on hosts defense-oriented or regulatory proteins such as immunoglobulins, interleukin-1, and protease inhibitors was investigated. The enzyme was found to degrade secretory immunoglobulin A (sIgA), IgG, and IgM. It also degraded interleukin-1alpha (IL-1alpha) and IL-1beta. Its activity was not inhibited by endogenous protease inhibitors, such as alpha2-macroglobulin, alpha1-trypsin inhibitor, and alpha2-antiplasmin. Furthermore, the enzyme rapidly degraded those endogenous protease inhibitors as well. The degradation of hosts defense-oriented or regulatory proteins by the Acanthamoeba proteinase suggested that the enzyme might be an important virulence factor in the pathogenesis of Acanthamoeba infection.
Acanthamoeba/*enzymology/pathogenicity ; Animals ; Endopeptidases/*physiology ; Immunoglobulins/*metabolism ; Interleukin-1/*metabolism ; Protease Inhibitors/*metabolism ; Support, Non-U.S. Gov't ; Virulence

No abstract available.
Ectromelia*