1.Thyrotoxic periodic paralysis.
Journal of Korean Society of Endocrinology 1993;8(1):15-18
No abstract available.
Paralysis*
2.Species Identification of the Genus Aeromonas Isolated from Freshwater Fish Culture-ponds and Seawater in Korea and Their Antibiotic Resistance Patterns.
Journal of the Korean Society for Microbiology 1999;34(4):393-400
Some species of mesophilic bacteria in the genus Aeromonas were isolated from a snakehead (Channa argus) culture-pond in the Myung-Ji area, a freshwater culture-pond in Pukyung National University, and seawater near the sewage treatment plant in Kwang-An Beach in Pusan. They were identified by biological characteristics, and their susceptibility to ten antibiotics including ampicillin, cefoxitin, ceftazidime cephalothin, cefotiam, chloramphenicol, nalidixic acid, rifampin, cefoperazone-sulbactam, and imipenem, was also studied. Four species in the genus Aeromonas, A. veronii biovar sobria (27 strains), A. caviae (14 strains), A. trota (1 strain), and A. schubertii (1 strain) were identified. A. trota, an unrecorded species in Korea, is reported for the first time in this study. Three strains of A. veronii biovar sobria showed multiple resistance to three kinds of antibiotics and one strain to four drugs. All strains of A. caviae were resistant to more than three drugs and seven strains to four drugs. A. trota was resistant to cephalothin and rifampin, but A. schubertii showed multiple resistance to ampicillin, nalidixic acid, and rifampin.
Aeromonas*
;
Ampicillin
;
Animals
;
Anti-Bacterial Agents
;
Bacteria
;
Busan
;
Cefotiam
;
Cefoxitin
;
Ceftazidime
;
Cephalothin
;
Chloramphenicol
;
Drug Resistance, Microbial*
;
Fresh Water*
;
Guinea Pigs
;
Imipenem
;
Korea*
;
Nalidixic Acid
;
Plants
;
Population Characteristics
;
Rifampin
;
Seawater*
;
Sewage
3.A Case of Spindle Cell Lipoma.
Sung Ku AHN ; Won Hyoung KANG ; Sung Nack LEE
Korean Journal of Dermatology 1990;28(6):810-813
A 50-year-old man developed 3cm sized, well-marginated, subcutaneous mass on the right upper back. Histopathologic finding showed the lipomatous tissue was replaced by a mixture of uniform spindle cells and mature fat cells that were closely associated with a mucoid matrix and a varying number of collagen fibers. The patient had been treated with excision and showed no evidence of recurrence.
Adipocytes
;
Collagen
;
Humans
;
Lipoma*
;
Middle Aged
;
Recurrence
4.A Case of Risperidone-induced Neuroleptic Malignant Syndrome.
Hwa Yeon KANG ; Yong Ku KIM ; Min Soo LEE
Journal of the Korean Society of Biological Psychiatry 1998;5(1):138-141
Neuroleptic malignant syndrome(NMS) is an uncommon but potentially fatal idiosyncratic reaction to neuroleptics, characterized by muscular rigidity, fever, autonomic dysfunction, and altered consciousness. The major theories to explain NMS is central dopaminergic blockade, but it is unclear. Risperidone is a new antipsychotic drug, a benzisoxazole derivative that blocks dopamine D2 receptor and serotonin type 2 receptor. The comparatively greater serotonin-blocking activity is believed to give risperidone the specific property of not causing any more extrapyramidal side effects than conventional antipsychotics at the optimal dose of 4-8mg/day. It is postulated that risperidone is unlikely to cause NMS. Here, we report a case of risperidone induced neuroleptic malignant syndrome.
Antipsychotic Agents
;
Consciousness
;
Fever
;
Muscle Rigidity
;
Neuroleptic Malignant Syndrome*
;
Receptors, Dopamine D2
;
Risperidone
;
Serotonin
5.Intraarticular Osteochondromatosis of the Ankle Joint: A Case Report
Myung Ku KIM ; Kang Hyun LEE ; Hee Kyun KOOK
The Journal of the Korean Orthopaedic Association 1995;30(1):161-165
Osteochondroma is the most common of the benign bone tumors. They are probably developmental malformations rather than true neoplasms. But rarely they develope in a joint, especially in the ankle joint. We reported a case of intraarticular osteochondromatosis of ankle joint.
Ankle Joint
;
Ankle
;
Joints
;
Osteochondroma
;
Osteochondromatosis
6.Giant Intra-articular Osteochondroma of the Knee: A Case Report
Kang Hyun LEE ; Soo Il KANG ; Chan Su PARK ; Myung Ku KIM ; Myung Seon KIM
The Journal of the Korean Orthopaedic Association 1990;25(3):973-975
The giant intra-articular osteochondroma of the knee is very rare and is probably result of synovial metaplasia of the fibrous capsule or of the adjacent connencive tissue of a joint, and of the fragment of articular cartilage. The gross findings and histology are consistent with the osteochondroma. The authors experienced a case of giant intra-articular osteochondroma of the right knee in a 19 years old man who had history of knee injury when he was 16 years old. The mass was excised and the symptome was relieved.
Cartilage, Articular
;
Joints
;
Knee Injuries
;
Knee
;
Metaplasia
;
Osteochondroma
7.Development of a LC-MS/MS for Quantification of Venlafaxine in Human Plasma and Application to Bioequivalence Study in healthy Korean Subjects.
Hyun Ku KANG ; Min A KANG ; Hyun Jin KIM ; Yoo Sin PARK ; Shin Hee KIM ; Ju Seop KANG
Translational and Clinical Pharmacology 2014;22(1):35-42
A simple, rapid and selective liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) is developed and validated for quantification of venlafaxine in human plasma with simple liquid-liquid extraction step consisted of extraction with ether and dichloromethane for 10 min and mixing with 1 M sodium acetate in human plasma using fluoxetine as an internal standard (IS). The analyte are separated using an isocratic mobile phase consisted of acetonitrile and 5 mM ammonium formate (4/3, v/v) on a isocratic YMC hydrosphere C18 (2.0x50.0 mm, 3.0 microm) column and analyzed by MS/MS in the multiple reaction monitoring (MRM) mode using the transitions of respective [M+H](+) ions, m/z 278.2-->260.3 and m/z 310.1-->148.1 for quantification of venlafaxine and IS, respectively. The standard calibration curves showed good linearity within the range of 1.0-200.0 ng/mL (r2=0.9986, 1/chi2 weighting). The lower limit of quantification (LLOQ) was 1.0 ng/mL. The retention times of venlafaxine and IS were 0.6 min and 0.7 min that means the potential for the high-throughput potential of the proposed method. In addition, no significant metabolic compounds were found to interfere with the analysis. Acceptable precision and accuracy were obtained for the concentrations over the standard curve range. The validated method was successfully applied to bioequivalence study after 75-mg of venlafaxine sustained-release (SR) capsule in 24 healthy Korean subjects.
Ammonium Compounds
;
Calibration
;
Chromatography, Liquid
;
Ether
;
Fluoxetine
;
Humans
;
Ions
;
Liquid-Liquid Extraction
;
Methylene Chloride
;
Pharmacokinetics
;
Plasma*
;
Sodium Acetate
;
Tandem Mass Spectrometry
;
Therapeutic Equivalency*
;
Venlafaxine Hydrochloride
8.The Assessment of Worker's Health Status by SF-36.
Bong Suk CHA ; Sang Baek KOH ; Sei Jin CHANG ; Jong Ku PARK ; Myung Guen KANG
Korean Journal of Occupational and Environmental Medicine 1998;10(1):9-19
This study was conducted to understand health status by general characteristic, and to find out relationship between social support and worker's health status. Health status was measured using SF-36(Medical Outcome Study Short Form 36), a 36 item self administered Instrument. The finding of this study were as follow; Mean scores of health status by sex were higher in male. The younger worker reported good health on physical functioning and role limitation-physical than did the older worker, but the older worker reported good health on social functioning and mental health. Mean scores of health status were higher in high income and white worker. When the relationship between social support and health status, social functioning, role limitation-emotion, mental health, vitality, general health were significantly related. Therefore we reviewed the evidence that socio-economic condition are associated with health status in this study, and that the strength of the social support was a important to maintain health.
Humans
;
Male
;
Mental Health
;
Outcome Assessment (Health Care)
9.Competitive exclusion against Salmonella gallinarum of Salmonella enteritidis infected chickens.
Young Ju LEE ; Min Su KANG ; Yong Ku WOO ; In Pil MO ; Ryun Bin TAK
Journal of Veterinary Science 2001;2(1):33-36
To evaluate the degree of competitive exclusion against Salmonella gallinarum(S. gallinarum) of Salmonella enteritidis(S. enteritidis) infected chickens, fifty-six, 4-week old Hyline layer suspected of S. enteritidis infection were challenged with S. gallinarum. All chickens were tested for S. enteritidis isolation using cloacal swabs and serum plate agglutination test using S. enteritidis Ag. before challenge and classified into four groups(SE isolated, SE nonisolated, SE seropositive and SE seronegative). None of the SE isolated and the SE seropositive groups died after challenge and the average weight gains were 245.5g and 254.6g, respectively. But in the SE nonisolated and the SE seronegative groups, mortality was 18.2% and 20.6% and the average weight gains were 150.1g and 111.2g. The incidence of reisolation of S. gallinarum of the SE isolated and the SE seropositive groups were 41.7% and 47.6% from liver, 33.3% and 47.6% from spleen and 8.3% and 14.3% from cecum, respectively, and the SE nonisolated and the SE seronegative group were 63.6% and 64.7% from liver, 84.1% and 88.2% from spleen and 47.7% and 52.9% from cecum. The serological response of the SE isolated and the SE seropositive groups hardly changed from 75.0 and 81.8% before challenge to 75.0 and 85.7% after. But, the other two groups were found to be significantly higher after challenge and increased from 0 and 18.2% to 100%. Consequently, S. enteritidis preinfected chickens were found to be significant different in terms of mortality, weight gain, reisolation of S. gallinarum and serological response compared to noninfected chickens. Moreover, our study shows that S. enteritidis infected chickens appear strong competitive exclusion against the colonization of S. gallinarum.
Animals
;
Chickens
;
Disease Outbreaks/veterinary
;
Korea/epidemiology
;
Oviposition
;
Poultry Diseases/*microbiology
;
Salmonella/*classification/*isolation & purification
;
Salmonella Infections, Animal/*microbiology
;
Salmonella enteritidis/*classification/*isolation & purification
;
Serotyping
;
Weight Gain
10.Upper Extremity Rehabilitation using Virtual Reality after Stroke.
Jeonghun KU ; Hyungjun IM ; Youn Joo KANG
Brain & Neurorehabilitation 2014;7(1):30-38
There is limited evidence regarding the use of virtual reality (VR) and interactive video gaming for improving arm function because there are few such commercial devices and little relevant research. However, evidence of the greater effectiveness of upper extremity VR training over that of conventional therapy after stroke has recently grown due to the adoption of various therapeutic devices. VR applications are novel and potent technologies for upper extremity rehabilitation after stroke because the interface technologies, augmented reality technologies, and various sensorimotor feedback techniques are rapidly advancing. Going forward, VR technology should be designed to provide the possibility of intense functional repetitive practice for patients. The combination of VR with robotic devices, neuromodulation, mirror therapy, and telerehabilitation may synergistically improve upper extremity function after stroke. In severely injured patients, robotic interfaces should be considered, the level of difficulty should be fitted appropriately to the severity of the deficits, and the fact that it is difficult to train patients repeatedly and effectively in a real-world environment should be considered. Further research should be conducted on the application of VR programs in larger populations, VR involving various training paradigms, VR at different exercise levels, and the long-term sustained effects of VR. In addition, synergistically enhanced effects of combining other treatments and feedback paradigms with well-designed interfaces should be investigated.
Arm
;
Feedback, Sensory
;
Humans
;
Rehabilitation*
;
Stroke*
;
Upper Extremity*