1.Thyrotoxic periodic paralysis.
Journal of Korean Society of Endocrinology 1993;8(1):15-18
No abstract available.
Paralysis*
2.Species Identification of the Genus Aeromonas Isolated from Freshwater Fish Culture-ponds and Seawater in Korea and Their Antibiotic Resistance Patterns.
Journal of the Korean Society for Microbiology 1999;34(4):393-400
Some species of mesophilic bacteria in the genus Aeromonas were isolated from a snakehead (Channa argus) culture-pond in the Myung-Ji area, a freshwater culture-pond in Pukyung National University, and seawater near the sewage treatment plant in Kwang-An Beach in Pusan. They were identified by biological characteristics, and their susceptibility to ten antibiotics including ampicillin, cefoxitin, ceftazidime cephalothin, cefotiam, chloramphenicol, nalidixic acid, rifampin, cefoperazone-sulbactam, and imipenem, was also studied. Four species in the genus Aeromonas, A. veronii biovar sobria (27 strains), A. caviae (14 strains), A. trota (1 strain), and A. schubertii (1 strain) were identified. A. trota, an unrecorded species in Korea, is reported for the first time in this study. Three strains of A. veronii biovar sobria showed multiple resistance to three kinds of antibiotics and one strain to four drugs. All strains of A. caviae were resistant to more than three drugs and seven strains to four drugs. A. trota was resistant to cephalothin and rifampin, but A. schubertii showed multiple resistance to ampicillin, nalidixic acid, and rifampin.
Aeromonas*
;
Ampicillin
;
Animals
;
Anti-Bacterial Agents
;
Bacteria
;
Busan
;
Cefotiam
;
Cefoxitin
;
Ceftazidime
;
Cephalothin
;
Chloramphenicol
;
Drug Resistance, Microbial*
;
Fresh Water*
;
Guinea Pigs
;
Imipenem
;
Korea*
;
Nalidixic Acid
;
Plants
;
Population Characteristics
;
Rifampin
;
Seawater*
;
Sewage
3.A Case of Spindle Cell Lipoma.
Sung Ku AHN ; Won Hyoung KANG ; Sung Nack LEE
Korean Journal of Dermatology 1990;28(6):810-813
A 50-year-old man developed 3cm sized, well-marginated, subcutaneous mass on the right upper back. Histopathologic finding showed the lipomatous tissue was replaced by a mixture of uniform spindle cells and mature fat cells that were closely associated with a mucoid matrix and a varying number of collagen fibers. The patient had been treated with excision and showed no evidence of recurrence.
Adipocytes
;
Collagen
;
Humans
;
Lipoma*
;
Middle Aged
;
Recurrence
4.Intraarticular Osteochondromatosis of the Ankle Joint: A Case Report
Myung Ku KIM ; Kang Hyun LEE ; Hee Kyun KOOK
The Journal of the Korean Orthopaedic Association 1995;30(1):161-165
Osteochondroma is the most common of the benign bone tumors. They are probably developmental malformations rather than true neoplasms. But rarely they develope in a joint, especially in the ankle joint. We reported a case of intraarticular osteochondromatosis of ankle joint.
Ankle Joint
;
Ankle
;
Joints
;
Osteochondroma
;
Osteochondromatosis
5.A Case of Risperidone-induced Neuroleptic Malignant Syndrome.
Hwa Yeon KANG ; Yong Ku KIM ; Min Soo LEE
Journal of the Korean Society of Biological Psychiatry 1998;5(1):138-141
Neuroleptic malignant syndrome(NMS) is an uncommon but potentially fatal idiosyncratic reaction to neuroleptics, characterized by muscular rigidity, fever, autonomic dysfunction, and altered consciousness. The major theories to explain NMS is central dopaminergic blockade, but it is unclear. Risperidone is a new antipsychotic drug, a benzisoxazole derivative that blocks dopamine D2 receptor and serotonin type 2 receptor. The comparatively greater serotonin-blocking activity is believed to give risperidone the specific property of not causing any more extrapyramidal side effects than conventional antipsychotics at the optimal dose of 4-8mg/day. It is postulated that risperidone is unlikely to cause NMS. Here, we report a case of risperidone induced neuroleptic malignant syndrome.
Antipsychotic Agents
;
Consciousness
;
Fever
;
Muscle Rigidity
;
Neuroleptic Malignant Syndrome*
;
Receptors, Dopamine D2
;
Risperidone
;
Serotonin
6.Giant Intra-articular Osteochondroma of the Knee: A Case Report
Kang Hyun LEE ; Soo Il KANG ; Chan Su PARK ; Myung Ku KIM ; Myung Seon KIM
The Journal of the Korean Orthopaedic Association 1990;25(3):973-975
The giant intra-articular osteochondroma of the knee is very rare and is probably result of synovial metaplasia of the fibrous capsule or of the adjacent connencive tissue of a joint, and of the fragment of articular cartilage. The gross findings and histology are consistent with the osteochondroma. The authors experienced a case of giant intra-articular osteochondroma of the right knee in a 19 years old man who had history of knee injury when he was 16 years old. The mass was excised and the symptome was relieved.
Cartilage, Articular
;
Joints
;
Knee Injuries
;
Knee
;
Metaplasia
;
Osteochondroma
7.Development of a LC-MS/MS for Quantification of Venlafaxine in Human Plasma and Application to Bioequivalence Study in healthy Korean Subjects.
Hyun Ku KANG ; Min A KANG ; Hyun Jin KIM ; Yoo Sin PARK ; Shin Hee KIM ; Ju Seop KANG
Translational and Clinical Pharmacology 2014;22(1):35-42
A simple, rapid and selective liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) is developed and validated for quantification of venlafaxine in human plasma with simple liquid-liquid extraction step consisted of extraction with ether and dichloromethane for 10 min and mixing with 1 M sodium acetate in human plasma using fluoxetine as an internal standard (IS). The analyte are separated using an isocratic mobile phase consisted of acetonitrile and 5 mM ammonium formate (4/3, v/v) on a isocratic YMC hydrosphere C18 (2.0x50.0 mm, 3.0 microm) column and analyzed by MS/MS in the multiple reaction monitoring (MRM) mode using the transitions of respective [M+H](+) ions, m/z 278.2-->260.3 and m/z 310.1-->148.1 for quantification of venlafaxine and IS, respectively. The standard calibration curves showed good linearity within the range of 1.0-200.0 ng/mL (r2=0.9986, 1/chi2 weighting). The lower limit of quantification (LLOQ) was 1.0 ng/mL. The retention times of venlafaxine and IS were 0.6 min and 0.7 min that means the potential for the high-throughput potential of the proposed method. In addition, no significant metabolic compounds were found to interfere with the analysis. Acceptable precision and accuracy were obtained for the concentrations over the standard curve range. The validated method was successfully applied to bioequivalence study after 75-mg of venlafaxine sustained-release (SR) capsule in 24 healthy Korean subjects.
Ammonium Compounds
;
Calibration
;
Chromatography, Liquid
;
Ether
;
Fluoxetine
;
Humans
;
Ions
;
Liquid-Liquid Extraction
;
Methylene Chloride
;
Pharmacokinetics
;
Plasma*
;
Sodium Acetate
;
Tandem Mass Spectrometry
;
Therapeutic Equivalency*
;
Venlafaxine Hydrochloride
8.A Case of Retinitis Punctata Albescens.
Journal of the Korean Ophthalmological Society 1982;23(3):773-777
Retinitis Punctata Albescens is a condition characterized by night blindness and the presence of multiple small discrete white dots scattered over the fundus except in the macular area. Progressive form is progressive loss of the visual field, deterioration of central vision, anomalies of color vision, night blindness, some optic atrophy and occasionally appearance of pigmentary changes. Stationary form is benign evolution, little or no constriction of the visual field, good visual acuity and the presence of white dots in the fundus without pigmentary changes. Recently, the authors have been experienced Retinitis Punctata Albescens in 50-year-old male whose complaint was night blindness and slight impairment of visual acuity. Clinical, ophthalmoscopic examination, visual field test, color vision test, fluorescein angiography and electroretinography were performed in patient.
Color Vision
;
Constriction
;
Electroretinography
;
Fluorescein Angiography
;
Humans
;
Male
;
Middle Aged
;
Night Blindness
;
Optic Atrophy
;
Retinitis*
;
Visual Acuity
;
Visual Field Tests
;
Visual Fields
9.The Seizure Outcome and Extent of Hippocampal Resection in Anterior Temporal Lobectomy.
Wan Su LEE ; Jung Kyo LEE ; Sang Am LEE ; Jung Ku KANG ; Tae Seong KO
Journal of Korean Neurosurgical Society 2000;29(12):1650-1656
No abstract available.
Anterior Temporal Lobectomy*
;
Seizures*
10.Contralateral Trochlear Palsy and Facial Sensory Change Due to Probable Brain Stem Vascular Malformation.
Journal of the Korean Neurological Association 1991;9(1):96-100
No abstract available.
Brain Stem*
;
Brain*
;
Paralysis*
;
Vascular Malformations*