No abstract available.
Pyloric Stenosis, Hypertrophic*

No abstract available.
Choledochal Cyst*

No abstract available.
Thyroid Gland* ; Thyroid Nodule*

No abstract available.
Head* ; Pancreas*

Giant cell tumor is a predominantly benign condition but often the tumor is locally aggressive and tends to have high rate of recurrence and it can evolve into a malignant tumor. Thus the lesions have a practically difficult therapeutic problem for the orthopaedic surgeon and any method of treatment has not been satisfied. Between March 1984 and March 1993, clinical observation was carried out on 22 cases of giant cell tumor of bone to analyse the recurrence rate and functional evaluation of the joint according to the treatment methods, pathological grade and cortical destruction. The mean follow-up time was 75. 2 months. The recurrence rate of the intralesional excision group was 54.5% and that of the wide excision group was 9%, There was no relationship between the pathologic grade and recurrence rate. There was no recurrent case in the grade I cortical destruction but almost all of recurrence was occurred in the grade I or II cortical destruction. The functional result of the giant cell tumor occurred around the knee joint was that the mean ratings in the intralesional excision group were 79% and in the wide excision group were 51%. In conclusion, to achieve better joint function and less recurrence rate, intralesional or marginal excision with heat using bone cement or with chemical cauterization using phenol and alcohol can be used for cases of radiological grade I or II, and wide excision for grade III.
Cautery ; Follow-Up Studies ; Giant Cell Tumor of Bone ; Giant Cell Tumors ; Giant Cells ; Hot Temperature ; Joints ; Knee Joint ; Methods ; Phenol ; Recurrence

PURPOSE: TGF-beta is a key regulator of epithelial-mesenchymal transition. Among the TGF-beta responses, cell migration is closely associated with the expression of matrix metalloproteinases (MMPs). Therefore, we determined which MMPs are regulated by TGF-beta and examined the TGF-beta signaling involved in this event, focusing on Src family tyrosine kinases (SFKs) METHODS: First we examined the expression of MMPs in rat lens explant culture treated with TGF-beta and LECs attached to the anterior capsules of patients with nuclear (N), anterior polar (AP) cataracts using RT-PCR and immunofluorescence staining. It was examined whether the expression of MMPs is regulated by SFKs. RESULTS: The study using RT-PCR and immunofluorescence staining showed the expression of MMP-2 and -14 in explants and the expression of MMP-14 LECs of AP cataracts. The expression of MMP-2 and -14 was blocked by PP2 in explants. Furthermore, the activated form of SFKs was observed in LECs of AP cataracts by immunofluorescence staining. CONCLUSIONS: We suggest a novel role of SFKs signaling in the expression of MMP-14 induced by TGF-beta.
Animals ; Capsules ; Cataract ; Cell Movement ; Epithelial Cells* ; Epithelial-Mesenchymal Transition ; Fluorescent Antibody Technique ; Humans ; Matrix Metalloproteinases ; Rats ; src-Family Kinases ; Transforming Growth Factor beta*

Observations were made by viewing 563 syphilics that were diagnos d and treated in the Department of Dermatology at Chon-nam University Hospital, for ten con- secutive years(1968 1977). During this ten-year period, the average percent of syphilitic cases seen was l. 72 of the yearly total outpatients. The yearly number of patients seen during this study period showed no consistent pattern of increase, however, there were particularly large numbers of patients seen in the last few years of the study, this indicating an increase in the trend of syphilis in our area. The large number of latent syphilitic cases (56. 3Y) seen, paticularly in the early latent stage, was reflected in total numbers as being of the greatest percentile And the ratio of early latent cases to primary and secondary cases averaged out to 1. 1: l during the ten-year period In 23. 2 percent of 190 women of child bearing age, pregnancies were terminated ly abortion or stillbirth. Of all cases, 9. 9 percent had other STDs in which the most frequent was scabies. As a follow up only 85 patients (15. 1Pl) underwent serial quantitative evaluation for 12 months or more, 6 of these patients (7M) were identified as serorelapse cases who should be retreated.
Child ; Dermatology ; Evaluation Studies as Topic ; Female ; Follow-Up Studies ; Humans ; Outpatients ; Pregnancy ; Scabies ; Sexually Transmitted Diseases ; Stillbirth ; Syphilis*

No abstract available.
Humans ; Spouses*

Observations of 50 sporotrichosis patients, who were confirmed by dinical, histopathological and mycological examination, were made in the department of Dermatology at Chon-nam University Hospital for the twelve year period from 1967 to 1978. The results obtained were as follows; 1. During this period, out of a total of 39, 594 outpatients, there were 50 cases of sporotrichosis for an average of 0. 13 percent. The highest incidence was in 1970 with 7 cases, however, there was no period with a particularly marked increase in the occurrence of the disease. 2. Half of all the cases occurred in the third and fourth decades of life. The male to female ratio was 2. 3:1. 3. Occupationally, the greatest percent were farmers, 36 cases(72%), and the next highest, unemployed. 4. In Kwang-ju an.d surrounding 6 counties, there were 25 cases which were widely scattered thraughout Chonnam province and the southern tip of Chonbuk province. 5. The initial lesion appeared on the upper extremities in 39 cases, particularly the right hand, and the lower extremities in 9 cases. 6. Of the total patients, there were 24 cases(48%) with a history of trauma before the onset of the disease. Of those cases, the disease appeared between I and 2 weeks. after trauma in 10 cases(41.7%) and between 2 and 3 weeks in 8 cases(33.3%). 7. The duration of the skin lesions before initial examination was 2 months in 12 cases(24%) and 3 months in 14 cases(28%). 8. Forty six percent of the total cases visited our department in spring, showing a higher incidence than any other season. The highest monthly incidence was in May, when there were 13 cases. 9, Of the total, 42 cases(84%) were cutaneous lymphatic type, while 8 cases(16%), localized cutaneous type.
Dermatology ; Female ; Gwangju ; Hand ; Humans ; Incidence ; Jeollabuk-do ; Jeollanam-do ; Lower Extremity ; Male ; Occupations ; Outpatients ; Seasons ; Skin ; Sporotrichosis* ; Upper Extremity

No abstract available.
Brain Abscess* ; Brain*