1.Action Mechanisms of Hormone Binding to Cell Surface Receptors: 3) TGF-beta; Binding to Serine-threonine Kinase Receptors and Action Mechanisms.
Journal of Korean Society of Endocrinology 2000;15(3):353-366
No Abstract Available.
Protein-Serine-Threonine Kinases*
;
Receptors, Cell Surface*
;
Transforming Growth Factor beta*
2.The Two Cases of Children with Buckwheat Allergy Confirmed by Oral Challenge Test.
Journal of the Korean Pediatric Society 1985;28(6):604-609
No abstract available.
Child*
;
Fagopyrum*
;
Humans
;
Hypersensitivity*
3.Crossroad between inflammation and carcinogenesis in colon.
Marie YEO ; Young Joon SURH ; Ki Baik HAHM
Korean Journal of Medicine 2006;70(2):130-137
Current evidences have expended the concept that chronic inflammation might play a crucial role in the development and progression of colorectal cancer. For instance, chronic ulcerative colitis (UC) is associated with a 10- to 40-fold increased risk of developing colorectal cancer (CRC) compared to the general population. However, the specific mechanistic link between chronic inflammation and carcinogenesis in colon has not been integrated into molecular understanding. In this current review, we will provide an update on the molecular pathogenesis of colitis-associated colorectal cancer, focused on 1) the differences of molecular mechanism between the colitis-associated colorectal cancer (CAC) and the sporadic colorectal cancer (SCC), 2) the plausible and contributive role of chronic inflammation in colon carcinogenesis, and 3) lessons learned from colitis-associated animal model. Understanding of molecular pathogenic mechanism underlying the colitis-associated colorectal cancer will facilitate the development of novel treatment strategies for prevention of colitis-associated colorectal cancer.
Carcinogenesis*
;
Colitis, Ulcerative
;
Colon*
;
Colorectal Neoplasms
;
Inflammation*
;
Inflammatory Bowel Diseases
;
Models, Animal
4.Surgical treatment of the acute subclavian artery thromboembolism due to thoracic outlet syndrome: a case report.
Cheol Hyun CHUNG ; Hee Jong BAIK ; Ki Bong KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(12):1497-1501
No abstract available.
Subclavian Artery*
;
Thoracic Outlet Syndrome*
;
Thromboembolism*
5.A Case of Chronic Bullous Dermatosis of Childhood.
Jeong Ki RHEE ; Sung Bum KANG ; Baik Kee CHO ; Won HOUH
Korean Journal of Dermatology 1988;26(5):708-713
We report a case of chronic bullous dermatosis of childhood occurring in a 8-year-old girl, who has multiple, pruritic, tense, vesicobullous eruptions on the both extremities and pelvic region without mucous membrane inuolvement. A skin biopsy revealed subepidermal vesicles infiltrated with many neutrophiles and a few eosinophiles. Direct immunofluorescent study of the perilesional skin demonstrated moderate intensity of linear IgA and to a lesser degree of IgG deposition at the dermoepidermal junction. The skin lesions responded dramatically to oral dapsone therapy, initially 4mg/kg, and taporing to 2mg/kg for 27 days.
Biopsy
;
Child
;
Dapsone
;
Eosinophils
;
Extremities
;
Female
;
Humans
;
Immunoglobulin A
;
Immunoglobulin G
;
Mucous Membrane
;
Neutrophils
;
Pelvis
;
Skin
;
Skin Diseases*
;
Transcutaneous Electric Nerve Stimulation
6.A Case of Papillary Eccrine Adenoma.
Jeong Ki RHEE ; Yung Jin OH ; Baik Kee HO ; Won HOUH ; Kyo Young LEE ; Sang In SHIM
Korean Journal of Dermatology 1989;27(5):616-620
The papillary eccrine adenoma is a rare benign sweat gland neoplasm charscterized by potentislly locally aggressive clinical course. We report herein a case of papillsry eccrine adenoma in a 28-year-old female who presented single intradermal tumor on the right postauricular ares. Histopathological findings showed dilated ducts containing eosinophilic or keratinous materials and intraluminal papillary rowths.
Adenoma*
;
Adult
;
Eosinophils
;
Female
;
Humans
;
Sweat Gland Neoplasms
7.A Case of Colonic Cavernous Hemangioma Misdiagnosed as a Pedunculated Polyp.
Journal of the Korean Society of Coloproctology 2009;25(2):125-128
Gastrointestinal hemangioma is a relatively uncommon benign vascular tumor that can occur anywhere in the gastrointestinal tract. It is the second most common vascular lesion of the colon and a clinically important entity because of the possibility of massive hemorrhage when complicated. In gross appearance, hemangioma presents variously as a pedunculated, subpedunculated, or flat elevated lesion similar to a submucosal tumor. A typical case of hemangioma is relatively easy to diagnose because the lesion presents as translucent blue-purple vessels under the mucosa. However, it can be difficult to diagnose in some cases, especially if it does not have its usual characteristic color or is covered with normal mucosa. We incidentally found a colonic hemangioma that had the unusual appearance of a pedunculated polypoid lesion with normal mucosa. It was misdiagnosed as a pedunculated polyp with a long, thick neck and treated by using an endoscopic mucosal resection.
Caves
;
Colon
;
Gastrointestinal Tract
;
Hemangioma
;
Hemangioma, Cavernous
;
Hemorrhage
;
Mucous Membrane
;
Neck
;
Polyps
8.Posterior thoracotomy under the prone position in children.
Ki Bong KIM ; Hee Jong BAIK ; Hyun SONG ; Sook Whan SUNG ; Joo Hyun KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(10):1000-1004
No abstract available.
Child*
;
Humans
;
Prone Position*
;
Thoracotomy*
9.A Case of Gastric Tuberculosis.
Hee Bong PARK ; Keun Wook BAIK ; Hwa Joong YIM ; Woong Ki CHANG ; Dong Joon KIM
Korean Journal of Gastrointestinal Endoscopy 1993;13(4):689-692
Gastric tuberculosis is a rare disease and the diagnoeis of gastric tuberculosis is based on either positive histological or bacteriological study. We experienced a case of gastric tuberculosis with pleural effuaion in 59 year-old woman, diagnosed by the histological study of the endoscopic biopsy specimen. Follow up endoscopic finding revealed marked improvement of gastric lesion after anti-tubercadoua medication. We reported the case with review of literature.
Biopsy
;
Female
;
Follow-Up Studies
;
Humans
;
Middle Aged
;
Rare Diseases
;
Tuberculosis*
10.Resolution of experimental intravitreal fibrin by tissue plasminogen activator.
Korean Journal of Ophthalmology 1990;4(2):58-65
Intravitreal fibrin clots were produced by intravitreal injection of 0.2 ml of autologous plasma in 62 rabbit eyes. The intravitreal injection of 0.25 micrograms or more of tissue plasminogen activator(tPA) resulted in a total clearing of intravitreal fibrin within one day in all treated eyes. This was significantly faster than in the control eyes, in which complete clearing was not seen until 8 days later. This represents the plateau on the dose-response curve in doses ranging from 0.25 to 200 micrograms. With light microscopy and transmission electron microscopy, retinal toxicity was demonstrated in eyes enucleated seven days after injection of 25 micrograms or more of tPA. This study demonstrates that tPA was effective and safe at 12.5 micrograms or less in clearing intravitreal fibrin in an experimental model. These results suggest that low dosages of tPA, probably of 3 micrograms or less, may be useful in the treatment of severe postvitrectomy fibrin formation seen clinically.
Animals
;
Disease Models, Animal
;
Dose-Response Relationship, Drug
;
Fibrinolysis/*drug effects
;
Rabbits
;
Retina/drug effects/pathology
;
Tissue Plasminogen Activator/*toxicity
;
*Vitreous Body