A total 147 cases of malignant tumors in children under 15 years of age who admitted Presbyterian Medical Center, Keimyung University for 6 years from Jan. 1973 to Dec. 1978 were analyzed clinically and the following results were obtained. 1) The incidence of malignancies on all admitted cases was 1.7% and the annual incidence was 1.4~2.0% without any annual increase of incidence on childhood malignancies. 2) The highest age incidence of childhood malignancy was noted in 1~5 years of age group(36.7%) 3) Males were more affected with the male to female ratio 1.8:1 4) Leukemia was the most common form of childhood malignancy(47.6%) followed by brain tumor (10.9%) and lymphoma (8.2%) in order. 5) Acute leukemia, retinoblastoma, wilm's tumor and neuroblastoma were seen most before the age og 5years. The lymphoma, brain tumor, and bone tumor have tendency to increase the incidence over the age of 5years. 6) Out of 147 cases of childhood malignancies, 102 cases(69.3%) have visited the pediatric department for first time. The common malignanies seeking pediatrician were accure leukemia, wilm's tumor, and neuroblastoma. 7) Out of 70 cases of acute leukemia, 32 cases(45.7%) were lymphocytic, 12 cases(17.1%), were myelogenous, and 15 cases (21.4%) were unclassified leukemia.
Brain Neoplasms ; Child* ; Female ; Humans ; Incidence ; Leukemia ; Lymphoma ; Male ; Neuroblastoma ; Protestantism ; Retinoblastoma ; Wilms Tumor

A total 147 cases of malignant tumors in children under 15 years of age who admitted Presbyterian Medical Center, Keimyung University for 6 years from Jan. 1973 to Dec. 1978 were analyzed clinically and the following results were obtained. 1) The incidence of malignancies on all admitted cases was 1.7% and the annual incidence was 1.4~2.0% without any annual increase of incidence on childhood malignancies. 2) The highest age incidence of childhood malignancy was noted in 1~5 years of age group(36.7%) 3) Males were more affected with the male to female ratio 1.8:1 4) Leukemia was the most common form of childhood malignancy(47.6%) followed by brain tumor (10.9%) and lymphoma (8.2%) in order. 5) Acute leukemia, retinoblastoma, wilm's tumor and neuroblastoma were seen most before the age og 5years. The lymphoma, brain tumor, and bone tumor have tendency to increase the incidence over the age of 5years. 6) Out of 147 cases of childhood malignancies, 102 cases(69.3%) have visited the pediatric department for first time. The common malignanies seeking pediatrician were accure leukemia, wilm's tumor, and neuroblastoma. 7) Out of 70 cases of acute leukemia, 32 cases(45.7%) were lymphocytic, 12 cases(17.1%), were myelogenous, and 15 cases (21.4%) were unclassified leukemia.
Brain Neoplasms ; Child* ; Female ; Humans ; Incidence ; Leukemia ; Lymphoma ; Male ; Neuroblastoma ; Protestantism ; Retinoblastoma ; Wilms Tumor

Two cases of Sturge-Weber disease in a 10 years old female and a 7 years old male were prese-nted. The diagnosis was established by charactristic features of Sturge-Weber disease including facial port-wine nevus, convulsion, typical ???ailread track pattern intracranial calcifications, some degree of mental retardation and hemiplegia. A brief review of related literature was made.
Child ; Diagnosis ; Female ; Hemiplegia ; Humans ; Intellectual Disability ; Male ; Nevus ; Seizures

The erectile response is peripherally mediated by cavernous nerve that contains thoracolubar sympathetic nerve and sacral parasympathetic nerve. It is known that thoracolubar sympathetic nerve involves in detumescence and sacral parasympathetic nerve in tumescence, however there are some opinions that rhoracolubar sympathetic nerve participates in psychogenic erectile mechanism. We previously reported that by the comparison with electrostimulation-induced erection, apomor- phine-induced erection was a vascular event. The aim of our study was to determine the infraspinal neural pathway of APO-induced erection. The sham operated rats remained normal in all measured respects. All rats having undergone neurotomy ot the hypogastric nerves showed APO-induced erection except one. The only 5 rats having undergone neurotomy of the pelvic nerves showed APO-induced erection. Erections could be elicited upon cavernous or pelvic nerves stimulation in all rats having undergone neurolomy of the hypogastric nerves. Among 17 rats having undergone neurotomy of the pelvic nerve erection could be elicited upon cavernous nerves slimulation in 14 rats, however. the intracavernous pressure (47.9+/-16.5 mmHg) was lower than that found in sham-operated rats. Erectile response in these 14 rats appeared to result from stimulation of penile neurons coming from the major pelvic ganglion. In contrast to no response in sham-operated rats, stimulation of the hypogastric nerves also resulted in erections in 7 out of 17 rats. In conclusion, this present study suggests that APO-induced ereclion is primarily mediated via the sacral parasympathetic nerve system and may be mediated by the thoracolumbar sympathetic pathway following injury to the parasympathetic nerve system. Furthermore we can guess the possibility that the neural pathway of psychogenic erection is same that of AP0- induced erection.
Animals ; Apomorphine ; Ganglion Cysts ; Models, Animal* ; Neural Pathways* ; Neurons ; Rats*

OBJECTIVE: This study is to evaluate the efficacy of terazosin in the treatment of overactive bladder (OAB) symptoms and sexual dysfunction in patients with symptomatic benign prostatic hyperplasia (BPH) and OAB. METHODS: Of 200 men aged 50-80 years with symptomatic BPH, an International Prostatic Symptom Score (IPSS) > or =8 accompanied by OAB symptoms, 185 patients completed treatment with terazosin 2-5 mg once daily for 8 weeks. Patients were asked to complete a voiding diary, the International Index of Erectile Function (IIEF) questionnaire, and the IPSS at baseline, 4 and 8 weeks. RESULTS: 8-week terazosin treatment improved OAB symptoms as well as reducing IPSS (19.8 to 12.7) and IIEF (34.4 to 37.4) scores. OAB symptoms improved significantly, irrespective of symptom severity by the IPSS, but the IIEF score only increased in patients with severe symptoms. CONCLUSIONS: Additional studies are needed to further evaluate the placebo effect. However, terazosin monotherapy is effective in patients with symptomatic BPH and OAB, and may increase sexual function in patients with severely symptomatic BPH.
Adrenergic alpha-Antagonists ; Humans ; Male ; Placebo Effect ; Prospective Studies* ; Prostatic Hyperplasia* ; Surveys and Questionnaires ; Urinary Bladder, Overactive*