Arotinolol was administered orally to 31 patients to evaluate is antihypertensive action. After one week of antihypertensive medication, they were given Arotinolol 30mg daily for 4 week. Routine serum chemistries, electrolytes, urinalysis and electrocardiography were studied before and after Arotinolol. Blood pressure measured in sitting, supine and standing position was 175.3+/-5.4/115.7+/-4.0, 168.0+/-5.2/150.0+/-3.8, 154.4+/-8.5/103.4+/-3.2mmHg in control and 143.8+/-2.8/93.3+/-2.8, 144.6+/-5.4/88.1+/-4.3, 139.7+/-4.6/86.8+/-3.4mmHg in Arotinolol treatment group. The differences between both blood pressure were statistically significant(P<0.01). No laboratory test showed significant difference between both period. There were no significant side effects except 2 cases of transient headache and dizziness respectively, and one case of diarrhea. In summary, Arotinolol apears to reduce blood pressure effectively with minimal side effects.
Blood Pressure ; Diarrhea ; Dizziness ; Electrocardiography ; Electrolytes ; Headache ; Humans ; Hypertension* ; Urinalysis

Affective Symptoms ; drug therapy ; etiology ; Female ; Fluoxetine ; therapeutic use ; Humans ; MELAS Syndrome ; complications ; psychology ; Middle Aged ; Serotonin Uptake Inhibitors ; therapeutic use ; Stroke ; complications ; psychology

Dupuytren's contracture is caused by a proliferative fibroplasia of the subcutaneous palmar tissue. It is most common in those of Scandinavian and Celtic origin, although it has rarely been reported in Orientals. Many types of surgery are advocated, all with apparent success. Then operative result of 23 cases of Dupuytren's contracture including seven bilateral involvment was analyzed partial fasciectomy was performed in all cases by one surgeon. Average follow-up period was 18 months. We analyzed the results of the operation, to Honner s classification. Excellent result was obtained in 6 cases(26%), good in 14(61%) fair in 3(13%), and poor in 0(0%). The complication were 8(34%) case as followshematoma 4(17%), stiffness 3(13%), skin necrnsis 1(4%). All patrents were not performed that skin graft and total fasciectomy. The partial fasciectomy is suggested as one of the successful method for the treatment of Dupuytren's contracture.
Classification ; Clinical Study ; Dupuytren Contracture ; Follow-Up Studies ; Methods ; Skin ; Transplants

The importance of the ticks in medical field has been emphasized because of their association with and transmission of various diseases. We report herein a case of tick bite in a 55-year-old male farmer, who visited our hospital on July 2, 1981 with a parasite attached on right lower flank and rice to small pea sized, pruritic erythematous papular skin eruptions on chest and right lower flank. The skin lesions disappeared completely with.in five days after removal of the parasite, which was identified with an adult female tick which belongs to Genus Ixodes.
Adult ; Female ; Humans ; Ixodes* ; Male ; Middle Aged ; Parasites ; Peas ; Skin ; Thorax ; Tick Bites* ; Ticks*

OBJECTIVE: According to development of web service technology and mobile device supply, mobile web service becomes an essential element of ubiquitous healthcare. But there are many constraints for offering mobile web services on mobile devices. Hence, this paper propose optimal system supplying web services about medical information in wired /wireless network according to resources of device. METHODS: Proposed system consists of web server, database, desktop subscriber, mobile device and mobile context server. When a mobile device requires the web service, a mobile context server rewrites and offers the equivalent contents provided from web server to suit the requiring device's resource. Our proposed system services the same medical information after its recomposition as the network and devices of user. RESULTS: The medical staff may require patient information in wired/wireless environment, web server and mobile context server supports their correct judgment and expeditious response by servicing optimized data of the patient according to the requiring device. CONCLUSION: Proposed system designed the wired/wireless integrated medical information system using web service and mobile web service as the bases of ubiquitous healthcare system. Not only for web service in wired network, to provide the optimal web service in wireless network, we should know the limited resource of mobile devices and appropriately divide the web contents of wired network to fit the mobile device's screen. The future research needs dynamic division of screen according to extension of medical information data.
Delivery of Health Care ; Humans ; Information Management* ; Information Systems ; Judgment ; Medical Staff

OBJECTIVE: The advancement of computing capabilities and increase of available network bandwidths have resulted in an emergency telemedicine services which can provide high quality medical services. However, existing telemedicine systems mainly have offered a one to one communication configuration instead of a multi-connection configuration. Therefore, we suggested a hybrid multimedia telemedicine system to support the multi-patients services in wired and wireless (heterogeneous) network environments. METHODS: We designed the hybrid multimedia telemedicine system consisting of 4 sub-systems, a patient system, a doctor system, a emergency monitoring system, and a multi-control server system. The patient system could deliver multimedia data of a patient to the emergency monitoring system or to the doctor system according to link configuration. The link configuration was decided as 'Flowing', or 'By-passing' in accordance the connection type of patient systems or doctor systems. At this time, as the multi-control server system considers the hybrid network, it monitored the patient's multimedia data and the state of emergency telemedicine services. RESULTS: The hybrid multimedia telemedicine system including the multi-control server system performed the best communication configuration over heterogeneous networks. This system achieved high quality emergency telemedicine services through dynamic wired and wireless networks at real-time. CONCLUSION: This study represented a hybrid multimedia telemedicine system over heterogeneous networks in emergency cases. We expected that the designed system could provide not only the high quality services, tele-diagnosis and tele-consultation, but also the effective emergency telemedicine services to multi-patients in the heterogeneous network environments.
Emergencies ; Humans ; Multimedia* ; Telemedicine*

OBJECTIVES: Individuals differ in their biological rhythms. This study investigated the association between the morningness-eveningness and sleep patterns, daytime sleepiness and fatigue in Korean male adolescents. METHODS: Participants were 501 eleventh grade male students (16.9+/-0.2 years of age) in one male high school in Seoul. Each student completed the Korean translation of composite scale (KtCS), Epworth sleepiness scale (ESS), Fatigue Severity Scale (FSS) and a questionnaire about their sleep schedule. RESULTS: The evening group had shorter weekday sleep time than the intermediate (p<0.001) or morning group (p=0.029). The evening group had more daytime napping (16.8%, p<0.001), high rate of caffeine use (58.8%, p<0.001) and snoring (18.5%, p=0.037). The evening group showed more daytime sleepiness (8.7, SD=3.2, p<0.001) and severe fatigue (4.4, SD=1.2, p<0.001) than the intermediate or morning group. CONCLUSION: Adolescents with eveningness have higher problems in weekday sleep, daytime sleepiness and fatigue. An intervention program for sleep problem in these adolescents should be considered.
Adolescent ; Caffeine ; Fatigue ; Humans ; Male ; Surveys and Questionnaires ; Snoring

OBJECTIVES: Individuals differ in their biological rhythms. This study investigated the association between the morningness-eveningness and sleep patterns, daytime sleepiness and fatigue in Korean male adolescents. METHODS: Participants were 501 eleventh grade male students (16.9+/-0.2 years of age) in one male high school in Seoul. Each student completed the Korean translation of composite scale (KtCS), Epworth sleepiness scale (ESS), Fatigue Severity Scale (FSS) and a questionnaire about their sleep schedule. RESULTS: The evening group had shorter weekday sleep time than the intermediate (p<0.001) or morning group (p=0.029). The evening group had more daytime napping (16.8%, p<0.001), high rate of caffeine use (58.8%, p<0.001) and snoring (18.5%, p=0.037). The evening group showed more daytime sleepiness (8.7, SD=3.2, p<0.001) and severe fatigue (4.4, SD=1.2, p<0.001) than the intermediate or morning group. CONCLUSION: Adolescents with eveningness have higher problems in weekday sleep, daytime sleepiness and fatigue. An intervention program for sleep problem in these adolescents should be considered.
Adolescent ; Caffeine ; Fatigue ; Humans ; Male ; Surveys and Questionnaires ; Snoring

PURPOSE: To evaluate the passive subluxation of the tibia on MR' images in patient with both anterior cruciate ligament (ACL) and medial collateral ligament (MCL) tears and to demonstrate the usefulness of its measurement. MATERIALS & METHODS: The authors performed a retrospective study of 123 knees with tears of both ACL (complete, n=70, partial, n=53) and MCL (complete, n=10, partial, n=113). ACL tears were documented at arthroscopy and MCL tears were interpreted by abnormal MR findings. One hundred normal knees were also studied for comparison. Using new internal landmarks, anterior subluxation was measured on an intercondylar sagittal image and lateral subluxation was measured on a mid-coronal image. RESULTS: Anterior subluxation of 3 mm or more was seen in 45/123(37%) abnormal knees, lateral subluxation of 3 mm or more in 20/123 (16%), and anterolateral subluxation in 15/123 (12%). Anterior subluxation of 5mm or more was seen in 25/70 (36%) complete ACL tears, and no knees with partial ACL tears showed anterior subluxation of 5 mm or more. CONCLUSION: Static anterolateral subluxation of the tibia occurs in knees with combined ACL and MCL tears, as measured on routine MR imaging. These measurements may help confirm the presence of ligament injuries and differentiate complete from partial ACLtear.
Anterior Cruciate Ligament ; Arthroscopy ; Collateral Ligaments* ; Humans ; Knee* ; Ligaments ; Magnetic Resonance Imaging ; Retrospective Studies ; Tibia*

AIM: To test the expression of erythropoietin (Epo) and its receptor EpoR in normal and neovascularized murine corneas induced by alkali burns, and to investigate whether Epo/EpoR is involved in the process of corneal angiogenesis.METHODS: The expression of Epo/EpoR was tested in normal and neovascularized murine corneas induced by alkali burns through immunohistochemistry of corneal frozen sections. Epo cloning, expression, and purification were carried out. Then Epo protein (6μL, 1μg) and control (6μ L of vector control or saline) were injected into the corneal stroma respectively, and the corneas were checked at the 14th day after injection to see whether corneal neovascuarization occurred.RESULTS: Epo/EpoR was expressed in epithelial cells, endothelial cells and stromal cells in normal and neovascularized corneas induced by alkaline burns, and also expressed strongly in neovascularized cornea. They were expressed at the same time in stromal inflammatory cells and new vessels. Corneal neovascularization was induced by Epo intrastromal injection in 5 out of 6 eyes ,but no new vessels were observed in all controls (n = 6) at day 14 after vector control or saline intrastromal injection in normal corneas.CONCLUSION: This paper first reported the expression of Epo and its receptor in normal and neovascularized cornea. Injection of Epo into the corneal stroma may induce the corneal neovascularization. Epo/EpoR is associated with the formation of corneal neovascularization.