Prostakath represents a new idea. The spiral shaped spring inserted in the prostatic urethra keeps the enlarged prostatic lobes compressing the urethra so far apart that self voiding is possible. The physiologic function of the external sphincter is maintained due to the special form of the spiral. Prostakath was inserted in 13 patients with benign prostatic hypertrophy who had long-term indwelling bladder catheters and anesthetic contraindications to an operation. Of the 13 patients 1 did not reach 3 months of follow-up due to removal of Prostakath. The remaining 12 patients were followed with clinical evaluation. urine cultures, retrograde urethrography and urine flow rates at 1 day and 3 months. Final evaluation at 3 months showed normal voiding in 83% of the patients with an absence of significant residual urine in all. In 8 patients (67%) urinary flow rates varied between 10 and 20cc per second and in the remaining it was less than 10cc per second. In 92 % of the patients follow up urine cultures were negative. We believe that placement of Prostakath permits selected patients to be freed from long-term indwelling bladder catheters. This is a valid alternatives a prostatic operation in high risk patients with benign prostatic hypertrophy.
Catheters ; Follow-Up Studies ; Humans ; Prostatic Hyperplasia* ; Urethra ; Urinary Bladder

Schwannoma also referred to as neurilemmoma, neurinoma, and perineural fibroblastoma, is an encapsulated nerve sheath tumor consisting of two components :a highly ordered cellular component (Antoni A area) and a loose, myxoid component (Antoni B area). It is usually solitary and may be benign or malignant, solid or cystic, encapsulated or diffuse. It is rarely occur in the retroperitoneal space. The term cellular Schwannoma is indicative of a Schwannoma composed predominantly of Antoni A type tissue. We report one case of retroperitoneal with brief review of literatures.
Neurilemmoma* ; Retroperitoneal Space

Schwannoma also referred to as neurilemmoma, neurinoma, and perineural fibroblastoma, is an encapsulated nerve sheath tumor consisting of two components :a highly ordered cellular component (Antoni A area) and a loose, myxoid component (Antoni B area). It is usually solitary and may be benign or malignant, solid or cystic, encapsulated or diffuse. It is rarely occur in the retroperitoneal space. The term cellular Schwannoma is indicative of a Schwannoma composed predominantly of Antoni A type tissue. We report one case of retroperitoneal with brief review of literatures.
Neurilemmoma* ; Retroperitoneal Space

The hyperprolactinemia is one of the common endocrinologic cause of impotence. If hyperprolactinemia is noted in serum of an impotence patient, the pituitary adenoma should be suspected. Recently we experienced a case of pituitary adenoma combined with impotence in 65 year old male. Herein we report this case with brief review of the literatures.
Aged ; Erectile Dysfunction* ; Humans ; Hyperprolactinemia ; Male ; Pituitary Neoplasms*

Incontinentia pigmenti (IP) is a rare X-linked dominant, multisystem genodermatosis that affects ectoderm-derived structures. Its cutaneous manifestations are usually subdivided into the vesicular, verrucous, hyperpigmented, and hypopigmented or atrophic stages. IP can also affect other ectoderm-derived structures, such as, hair, nails, teeth, eyes, and the central nervous and musculoskeletal systems. About 80% of IP patients have genomic deletions of exons 4~10 of the NEMO (NF-kappaB-Essential MOdulator) gene, also known as the IKKgamma (gamma-subunit of the inhibitor kappaB kinase), which is essential for the activation of the NF-kappaB pathway. The female infant presented in this case report was born to healthy non-consanguineous parents and showed vesiculopustular eruptions with a NEMO gene rearrangement. No IP case has been previously reported to be related to a NEMO gene mutation in South Korea. In other words, this is the first report to confirm the relation between IP and mutation of the NEMO gene in Koreans.
Exons ; Eye ; Female ; Gene Rearrangement ; Hair ; Humans ; Incontinentia Pigmenti ; Infant ; Musculoskeletal System ; Nails ; NF-kappa B ; Parents ; Republic of Korea ; Tooth

In 1, 345 patients suspected of having pancreatic or biliary tract disease, 23 patients were shown to have biliary ascariasis demonstrated by endseopic retrograded cholangiopancreatog raphy, at Kwang Ju Christian Hospital from Sep. 1976 to Aug. 1983. Authors report the clinical study and ERCP finding of 23 cases of biliary ascariasis. The result were as follows. 1) Out of 1,345 cases of ERCP, biliary ascariasis were 28 cases, The ascaris were found in CHD & IHD in 21 cases, and 2 casee were found in Ampulla of Vater. 2) There was no specifia age incidence and male to female ratio was 1: 1.9, 3) The disease was more prevalent in spring & summer, and more prevalent in rural area than urban area. 4) The chief eomplaints were RUQ and epigastric abdominal pain. The cases which were admitetted within 2weeks of onset were 16 cases. 5) Ascaris in biliary tract were removed by operation in 14 cases, and EST were performed in 5 cases. Two cases werere moved by DORMIA basket under the endoscopic direct visualization. 6) We report E.S.T. as a new therapeutic method of biliary ascariasis.
Abdominal Pain ; Ampulla of Vater ; Ascariasis* ; Ascaris ; Biliary Tract ; Biliary Tract Diseases ; Cholangiopancreatography, Endoscopic Retrograde ; Diagnosis* ; Female ; Gwangju ; Humans ; Incidence ; Male

Autosomal dominant neurohypophyseal diabetes insipidus is a rare form of central diabetes insipidus that is caused by mutations in the vasopressin-neurophysin II (AVP-NPII) gene. It is characterized by persistent polydipsia and polyuria induced by deficient or absent secretion of arginine vasopressin (AVP). Here we report a case of familial neurohypophyseal diabetes insipidus in four generations of a Korean family, caused by heterozygous missense mutation in exon 2 of the AVP-NPII gene (c.286G>T). This is the first report of such a case in Korea.
Arginine Vasopressin ; Diabetes Insipidus, Neurogenic* ; Exons ; Family Characteristics* ; Humans ; Korea ; Mutation, Missense ; Polydipsia ; Polyuria

Several studies have previously reported that exposure to stress provokes behavioral changes, including antinociception, in rodents. In the present study, we studied the effect of acute cold-water (4°C) swimming stress (CWSS) on nociception and the possible changes in several signal molecules in male ICR mice.Here, we show that 3 min of CWSS was sufficient to produce antinociception in tailflick, hot-plate, von-Frey, writhing, and formalin-induced pain models. Significantly, CWSS strongly reduced nociceptive behavior in the first phase, but not in the second phase, of the formalin-induced pain model. We further examined some signal molecules' expressions in the dorsal root ganglia (DRG) and spinal cord to delineate the possible molecular mechanism involved in the antinociceptive effect under CWSS.CWSS reduced p-ERK, p-AMPKα1, p-AMPKα2, p-Tyk2, and p-STAT3 expression both in the spinal cord and DRG. However, the phosphorylation of mTOR was activated after CWSS in the spinal cord and DRG. Moreover, p-JNK and p-CREB activation were significantly increased by CWSS in the spinal cord, whereas CWSS alleviated JNK and CREB phosphorylation levels in DRG. Our results suggest that the antinociception induced by CWSS may be mediated by several molecules, such as ERK, JNK, CREB, AMPKα1, AMPKα2, mTOR, Tyk2, and STAT3 located in the spinal cord and DRG.

Several studies have previously reported that exposure to stress provokes behavioral changes, including antinociception, in rodents. In the present study, we studied the effect of acute cold-water (4°C) swimming stress (CWSS) on nociception and the possible changes in several signal molecules in male ICR mice.Here, we show that 3 min of CWSS was sufficient to produce antinociception in tailflick, hot-plate, von-Frey, writhing, and formalin-induced pain models. Significantly, CWSS strongly reduced nociceptive behavior in the first phase, but not in the second phase, of the formalin-induced pain model. We further examined some signal molecules' expressions in the dorsal root ganglia (DRG) and spinal cord to delineate the possible molecular mechanism involved in the antinociceptive effect under CWSS.CWSS reduced p-ERK, p-AMPKα1, p-AMPKα2, p-Tyk2, and p-STAT3 expression both in the spinal cord and DRG. However, the phosphorylation of mTOR was activated after CWSS in the spinal cord and DRG. Moreover, p-JNK and p-CREB activation were significantly increased by CWSS in the spinal cord, whereas CWSS alleviated JNK and CREB phosphorylation levels in DRG. Our results suggest that the antinociception induced by CWSS may be mediated by several molecules, such as ERK, JNK, CREB, AMPKα1, AMPKα2, mTOR, Tyk2, and STAT3 located in the spinal cord and DRG.

We describe a case of secondary hypertension caused by renal arteriovenous fistula. An 8-year old girl was hospitalized with a severe headache, vomiting, and seizure. Renal angiography demonstrated multiple renal arteriovenous fistula and increased blood renin concentration in the left renal vein. Thus, left renal arteriovenous fistula and renin induced secondary hypertension were diagnosed. Her blood pressure was well controlled by medication with angiotensin converting enzyme inhibitor.
Angiography ; Arteriovenous Fistula ; Blood Pressure ; Headache ; Hypertension ; Peptidyl-Dipeptidase A ; Renal Veins ; Renin ; Seizures ; Vomiting