No abstract available.
Tuberculosis, Multidrug-Resistant ; Tuberculosis, Pulmonary*

No abstract available.

No abstract available.
Radiopharmaceuticals*

This study was designed to evaluate the results of anterior cruciate ligament(ACL) reconstructions with ligament augmentation device(Kennedy LAD; 3M Co., St. Paul, MN, USA) in chronic injury. Eighteen patients with chronic ACL insufficiency were treated by ACL reconstruction using bone- patellar tendon-bone/LAD composite graft. The patients were followed up more than 5 years and the lat- est follow-up results are presented here. Evaluations were based on the Lysholm functional score, Lachman test and pivot-shift test. Data were analysed using the SPSS software. There were 9 patients(50%) with a Lysholm score more than 84(excellent or good) at latest follow-up. This postoperative improvement of Lysholm score was sta- tistically significant, P=0.001. There was no serious perioperative complications. Rehabilitation was not prolonged. This study demonstrated that a synthetic graft augmentation may improve results. However, no significant advantages have been observed with the use of LAD to augment patellar tendon. The com- parison study of ACL reconstruction with and without Kennedy LAD is recommended to assess the possi- ble effects of the addition of the LAD. And routine use of LAD should not be advocated in uncomplicated reconstruction of ACL using biological graft.
Follow-Up Studies ; Humans ; Ligaments ; Patellar Ligament* ; Rehabilitation ; Transplants*

No abstract available.
Anterior Cruciate Ligament*

No Abstract available.
Consensus* ; Infection Control*

No Abstract available.
Chungcheongnam-do* ; Infection Control*

The insulin-like growth factor (IGF)s are believed to one of several growth factors that play an adjunctive role in ovarian follicular development. These factors circulate bound to a family of IGF-binding protein (IGFBP)s. It is known that circulating IGFBPs are involved in the transport of IGFs to tissues and modulate IGFs actions at local tissue. The purposes of this study were to evaluate changes in serum IGFBPs profiles during normal ovulatory menstrual cylce and to compare serum IGFBPs profiles in periovulatory phase of between normal ovulatory menstrual cylce and controlled hyperstimulated cycle. Fasting blood samples were obtained from 15 normal healthy women throughout normal ovulatory menstural cycle and on the day of aspiration of oocyte from 10 patients undergoing ovarian hyperstimuation for in vitro fertilization-embryo transfer. Serum IGFBP-1-IGFBP-4 were measured by western ligand blot and immunoprecipitation. Serum 17beta-estradiol was determined by radioimmunoassay. Type and molecular weight of serum IGFBP did not changed during normal ovulatory menstural cycle. No significant variation in the relative proportion and level of each IGFBP was found throughout normal ovulatory menstural cyle. Also, the relative proportion and level of each IGFBP did not correlated with serum 17beta-estradiol level. There was no significant difference in the relative proportion and level of each serum IGFBP between on the day of ovulation in normal ovulatory menstrual cylce and on the day of aspiration of oocyte in controlled hyperstimulated cycle. Our data indicate that IGFBPs have regulatory functions in ovary through an paracrine and autocrine rather than endocrine mechanism during normal ovulatory menstural cycle.
Fasting ; Female ; Humans ; Immunoprecipitation ; Insulin-Like Growth Factor Binding Proteins* ; Intercellular Signaling Peptides and Proteins ; Menstrual Cycle* ; Molecular Weight ; Oocytes ; Ovary ; Ovulation ; Radioimmunoassay

No abstract available.
Foot*

OBJECTIVE: To assess the potential clinical utility of in-vivo 31P magnetic resonance spectroscopy (MRS) in patients with various malignant and benign breast lesions. MATERIALS AND METHODS: Seventeen patients with untreated primary malignant breast lesions (group I), eight patients with untreated benign breast lesions (group II) and seven normal breasts (group III) were included in this study. In-vivo 31P MRS was performed using a 1.5 Tesla MR scanner. Because of the characteristics of the coil, the volume of the tumor had to exceed 12 cc (3 x 2 x 2 cm), with a superoinferior diameter at least 3 cm. Mean and standard deviations of each metabolite were calculated and metabolite ratios, such as PME/PCr, PDE/PCr, T-ATP/PCr and PCr/T-ATP were calculated and statistically analyzed. RESULTS: Significant differences in PME were noted between groups I and III (p=0.0213), and between groups II and III (p=0.0213). The metabolite ratios which showed significant differences were PME/PCr (between groups II and III) (p=0.0201), PDE/PCr (between groups I and III, and between groups II and III) (p=0.0172), T-ATP/PCr (between groups II and III) (p=0.0287), and PCr/T-ATP (between groups II and III) (p=0.0287). There were no significant parameters between groups I and II. CONCLUSION: In-vivo 31P MRS is not helpful for establishing a differential diagnosis between benign and malignant breast lesions, at least with relatively large lesions greater than 3 cm in one or more dimensions.
Adult ; Breast Neoplasms/*diagnosis/*metabolism ; Diagnosis, Differential ; Female ; Human ; Magnetic Resonance Spectroscopy/*methods ; Middle Age ; Phosphates/metabolism ; Tumor Markers, Biological/metabolism