The present study was performed to evaluate clinical manifestations in 26 patients and histopathological findings in 19 patients with Behcets syndrome. 1. Clinical findings: A. Among the 26 patients, 9 were male and 17 were female (male to female ratio was 1: l.9). The age at onset of the disease varied from 10 to 62, with a mean of 26.9. B. The incidence of the major clinical manifestations: The oral ulcers were observed in all of the 26 patients, genital ulcers in 21 patients (81%), cutaneous manifestations in 25 patients (96%) and ocular lesions in 7 patients (27%). C. Saline intradermal test was positive in 62% and PPD intradermal test in 42% 2. Histopathological findings: Fourty-one specimens were taken frorn 19 patients with Behcets syndrome; Erythema nodosum like lesions (15), edematous papules (3), acneiform eruption (1), oral ulcers (4), genital ulcers (8), saline intradermal injection sites (5) and PPD intradermal test sites (5). As a control, 4 specirnens were taken from PPD test sites of the patients with erythem nodosum. The common histopathological findings were perivascular inflammatory cell infiltration, mainly composed of neutrophils and nuclear dusts, and vasculitis of varying degree. A. Cutaneous lesions; In erythema nodosum-like lesions main pathologic foci were in the deep dermis and/or the subcutis, and moderate to severe vasculitis were observed. In edematous papules, however, main foci were in the pa,pill- ary dermis and the upper dermis, papillary dermal edema was prorninent, and vasculitis was rather mild.
Acneiform Eruptions ; Behcet Syndrome* ; Dermis ; Dust ; Edema ; Erythema ; Erythema Nodosum ; Female ; Humans ; Incidence ; Injections, Intradermal ; Intradermal Tests ; Male ; Neutrophils ; Oral Ulcer ; Ulcer ; Vasculitis

Subepiderral calcified nodules is a special form of idiopathic calcinosis circumscripta with its distinct clinical and histopathologic features, which was originally described by Winer(1952) as solitary congenital no3ular czlcification of the skin. Although the lesions are usually solitary and congenital, subs aquent investigators reported multiple lesions and later onset. Clinically, th. leions are small hard. yellowish-white warty nodules developed. usually on the face and mostly in children and histopathologically are subepidermal calcified mass with s cvn4ry epidermal changes. Although the pathogenesis is still unexplained, it s seems that the disease is not associated with any systemic or cutaneous disease or any biochemial abnormalities. We present a first recorded case of subepidermal calcified no3ules developed on the left the a Korasn female, aged 23, which has been present for 7 years. Shave biopsy showed typical histopathologic and histochemical features of the subpidermal calcified nodules. Literature were reviewed.
Biopsy ; Calcinosis ; Child ; Female ; Humans ; Research Personnel ; Skin

Chronic liver disease was characterized difficult to cure, long-standing disease. Patients with chronic liver disease were searching for complementary treatments to recover form illness, while they have been treated by the doctor. This study was carried out to explore application of alternative therapies in patients with chronic liver disease. For this survey, the questionnaire were developed by researchers and the data were collected for two months. Among the 192 subjects, 155 were hospitalized and 37 were out patient department and the majority of diagnoses were chronic hepatitis (42.2%), liver cirrhosis (31.3%), primary liver carcinoma (14.6%). The results were as follows. 1. Patients who have had experiences with alternative therapies were 128, not undergone were 64. Varried alternative therapies were used and 46.9% of 128 subjects used both hospitals and alternative therapies simultaneously. 2. Patients have looked for alternative therapies in the early stage of disease (71.1%), and motivated to decide a matter of having use complementary therapies as alternatives for treatments (64.8%), and obtained information from their families and friends (48.2%), mass media (14.8%). The majority of patients were acknowledged that laternative treatments have no effectiveness really but it gives them psychological comfort. And the patients have payed a lot of money in cost of alternative therapies fee ; 1.4 times higher than hospitals. 3. Among the 128 subjects, 43.8% patients were communicated with their physicians about complementary therapies, 56.2% were not. 82.1% patients who asked their physicians were experienced negative responses of their doctors. 4. patients were expected the higher effect of alternative therapies when they have been delivered treatment by hospitals with complementary therapies (chi2=57.84, P<0.05), and then they evaluated the treatment effect better in this treatment pattern (chi2=25.26, P<0.05). And in terms of general characteristics of the patients, the only duration of illness was showed the significant relationship with the utilization of alternative therapies (chi2=8.44, P<0.05). 5. In no used alternative therapies group, the reason that they have not taken alternative therapies were ; to keep their physician's prescription, to refuse alternative therapies by their physicians, and to have no trust themselves on alternative therapies. In conclusion, the further study will be required the patients' experience using alternative therapies as the progress of disease in terms of holistic view of patients.
Complementary Therapies* ; Diagnosis ; Fees and Charges ; Friends ; Hepatitis, Chronic ; Humans ; Liver Cirrhosis ; Liver Diseases* ; Liver* ; Mass Media ; Prescriptions ; Surveys and Questionnaires

Roots of manually extracted scalp hairs among 86 healthy Koreans in different age groups were examined microscopically and the proportion of resting hairs to growing hairs were determined with the fol[owing results. 1. The proportion of resting hairs in all age groups was 10. 9% and there was no significant difference between male and female. 2. In each age group the proportion of resting hairs show's difference, being lowest (6. 8%) in below 9 years age group, increasing the rate by increasing the age group, highest (19. 7%) in over 60 years age group. 3. The proportion of resting hairs below the age of 29 years was below 10%, above 30 years to 49 years in between 10% to 15% and over 50 years in between 15% to 20%. 4. The normal range of the proportion of resting hairs among normal Koreans was below 20%.
Dermatitis, Atopic* ; Female ; Hair ; Humans ; Male ; Neutrophils* ; Reference Values ; Scalp

We compared the sensitivity and practicability for the direct examination of fungal hypae between the specimens treated with mixed Chlorazol black E solution and simple KOH(potassium hydroxide) solution in 118 cases of superficial myosis. The results were as follows: Higher positivity of fungal hypae in the specimens treated with mixed Chlorazol black E solution(99. 2%) than simple KOH solutiion(87. 3%.). 2, It was time-saving and easy to detect fungal hypae in the specimens treated with mixed Chlorazol black E solution than simple K(3H solution.
Diagnosis*

The prevalence of dermographism in 96 patients of acute or chronic urticaria was studied using dermographic tester. The results were summarized as follows : 1. The prevalence rate of dermographism in acute or chronic urticaria was 26.0% (25/96). 2. Dermographism was more common in acute or chronic urticaria than in the general population(p<0.005). 3. There was no significant difference in the prevalence rate of dermographiam between acute and chronic urticaria. 4. The prevalence rate of dermographism was not significantly correlated with the level of serum IgE.
Humans ; Immunoglobulin E ; Prevalence ; Urticaria*

The purpose of this study was to investigate the relation between hypertension and risk factors. A positive association between obesity, age, serum lipid and such life style factors as smoking, exercise, alcoholic beverage use with blood pressure problems and the prevalence of hypertension has been described in many studies. Therefore to identify and evaluate the effects of variables, which were known to be related to hypertension, multiple regression analysis was performed. We studied 110 subjects. The participants were 45 men and 65 women who visited one university hospital located in Seoul from January to December 1998. All 110 persons were identified as having primary hypertension by their physicians. The significant risk factors identified for hypertension were Obesity, BMI, length of time with hypertension. The results were as follows; 1. The systolic blood pressure average in 110 subjects was 156.65mmHg +/- 14.08mmHg, the diastolic blood pressure average was 100.73mmHg +/- 5.64mmHg. 18.2% of the subjects were smokers, 26.4% of the subjects were drinkers, and 33.6% of the subjects exercised regularly. 13.6% had a family history of hypertension. The average mean pressure was 119.37 +/- 7.40mmHg. The average history of hypertension was 28.36 +/- 34.56months. The average body weight of subjective was 65.25kg, and their average BMI was 24.54kg/m2. The average serum cholesterol of the subjects was 204.54mg/dl, HDL was 50.93mg/dl. 2. The result of this study were that variables which showed significance rationale for high systolic blood pressure in hypertension were mean arterial pressure(R2=0.808), and age(R2=0.032). And the variables which showed significance rationale for diastolic blood pressure in hypertension were mean arterial pressure(R2=0.697), age(R2=0.051), sex(R2=0.014), and somking(R2=0.010). And the best variable for prediction of mean blood pressure was the length of history of the disease. 3. According to multiple regression analysis by demographic variables, age and the length of history of hypertension were predictable variables for hypertension. And mean the blood pressure was identified best explaining variable of hypertension by biophysical variables. Therefore, life style modification for hypertension patients as a primary regimen is less important than for normal blood pressure patients. Life style modification is important intervention for normal blood pressure subjects, on the other hand drug therapy and its compliance is the most important intervention for hypertensive subjects. So to regulate blood pressure and prevent the complication of hypertension, the first regime of all should pharmacologic therapy. There is a need to develop nursing intervention to improve pharmacologic compliance for primary hypertension patients.
Alcoholic Beverages ; Blood Pressure* ; Body Weight ; Cholesterol ; Compliance ; Drug Therapy ; Female ; Hand ; Humans ; Hypertension* ; Life Style ; Male ; Nursing ; Obesity ; Prevalence ; Risk Factors* ; Seoul ; Smoke ; Smoking

A 24-year-old female who have had pseudoxanthoma elasticum for 14 years, showed brownish, umbilicated papules forming serpiginous pattern on the anterior neck, A skin biopsy specimen from the neck lesion revealed epidermal hyperplasia and perforating canal containing basophilic, necrotic materials and degenerated elastic fibers, also showed short, swollen and irregularly clumped elastic fibers in the lower dermis.
Basophils ; Biopsy ; Dermis ; Elastic Tissue ; Female ; Humans ; Hyperplasia ; Neck ; Pseudoxanthoma Elasticum* ; Skin ; Young Adult

The serum value of immunoglobulin E (IgE) in 47 cases of atopic dermatitis and 43 cases of urticaria were determined by Phadebas PRIST(R) method in department of dermatology at National Medical Center, from Jan., 1982 to Sep., 1982. The results were as follow; 1. The mea,n IgE value in atopic dermatitis was significantly higher (408+/-l43 u/ml) than that of normal subjects (p>0.01). 2. The mean value of IgE in urticaria (310+/-299 u/ml) was not significantly higher than tha,t of normal subjects (p>0.05). 3. The rnean value of IgE in severely expanded atopic dermatitis (664+/-404 u/ml) was significantly increased than that of normal subjects (p>0.01) 4. The mean value of IgE in 7 cases of atopic dermatitis with allergic respiratory diseases (817+/-233 u/ml) was significantly elevated (p>0.01). 5. No close correlation was seen between IgE value and eosinophilia. 6. IgE in 2 cases of the urticaria infested with PW, CS were extended over 1000u/ml.
Dermatitis, Atopic ; Dermatology ; Eosinophilia ; Immunoglobulin E* ; Immunoglobulins ; Skin Diseases* ; Urticaria

No Abstract Available.