Since almost all patients suffering from acute hematogenous osteomelitis, due to Staph. aureus, are under 20 year old, it may be assumed that the host-parasite relationships, between the young and actively growing bodies and the organisms, might be somewhat different from the ones prevailed in the adult bodies. And it is also known that the administration of various hormones may produce significant influences upon the susceptibity and resistance of host. It was thought worthwile to study the host reactions to the introduction of organisms and the effects of cortisone or prehormone administration to the infected animals. Thus, ca. 5×10⁷ viable cells of Staph. aureus were inoculated i.v. into young rabbits, weighing 1–1.5 kg., of around 2 months old. The number of viable units of Staph. aureus were followed in the circulating blood and urine of the inoculated animals with or without treatment of cortisone or prehormone. The results of observations might be summerized as follows: 1. The organisms were removed rapidly from the circulating blood of infected rabbits without treatment. The number of viable units increased more or Iess slowly, peak being three to eight days after inoculation, in the urine of infected rabbits without treatment. 3. In the of infected rabbits with daily administration of cortisone, small number of organisms could be cultured throughout the 17 days of observation. 4. The number of viable units in the urine of infected rabbits with daily adminstration of cortisone sho wed significant increase upon the onset of cortisone administration and then decreased slowly. 5. Prehormone administration appeared to produced no significant influence on the number or viable stapylococci in the blood and urine of infected rabbits.
Adult ; Animals ; Cortisone ; Host-Parasite Interactions ; Humans ; Rabbits ; Staphylococcus aureus ; Staphylococcus

No abstract available.
Lipomatosis*

No abstract available.
Kallmann Syndrome*

No abstract available.
Paraplegia* ; Spondylitis, Ankylosing*

No abstract available.
Fracture Fixation, Intramedullary*

BACKGROUND: Hydrocarbon is used frequently in the home in places such as the kitchen, garage, and basement. Accidental ingestion of hydrocarbons occurs generally in infants and children in the home. In cases of accidental ingestion, the amount is usually too small to cause medical problems, but can bring about diseases such as chemical pneumonitis. CASE REPORT: After ingesting organic solvent mistaken for mineral water, a 53-year-old male complained of cough, fever, and pain in the right upper abdomen, back, and right chest. Simple chest x-ray revealed focal chemical pneumonitis mainly involving the right middle lobe. The resulting lung abscess did not resolve until after treatment with drainage accompanied with antibiotics therapy. The ingested solution was analyzed and found to be a C11~C13 hydrocarbon mixture which has low viscosity. CONCLUSION: Chemical pneumonitis occurred after ingestion of hydrocarbon solution, and there is evidence of aspiratory mechanism.
Abdomen ; Anti-Bacterial Agents ; Child ; Cough ; Drainage ; Eating ; Fever ; Humans ; Hydrocarbons ; Infant ; Lung Abscess ; Male ; Middle Aged ; Mineral Waters ; Pneumonia ; Thorax

STUDY DESIGN: This is a retrospective study. OBJECTIVES: We wanted to analyze the radiological features of degenerative lumbar spondylolisthesis and retrolisthesis, and we wanted to verify what radiological factors are related to the development of the retrolisthesis. We also wanted to determine these radiological factors' clinical significance. SUMMARY OF THE LITERATURE REVIEW: There is little information about the pathological mechanism and the clinical and radiological aspects of degenerative lumbar retrolisthsis. MATERIALS & METHODS: Sixty patients were reviewed and divided into three groups. The degenerative lumbar retrolisthesis patients were in group A. The degenerative lumbar spondylolisthesis patients were in group B. Group C patients had no vertebral shift in any direction. The factors we measured were the facet joint angle, the disc height of L3-4, L4-5 and L5-S1, and the lordosis of the lumbar spine. The evaluation of the clinical results was then quantified. RESULTS: The facet joint angle showed no statistical significance between the two groups. The disc height of group A at L4-5 and L5-S1 was more decreased in group A than in group B (p<0.05). Lumbar lordosis was decreased significantly in group A (p<0.05). The preoperative pain was improved at the final follow up, but preoperative pain was significantly higher in group A than in group B (p<0.05). The clinical results were improved in each group, but there was no statistically significant difference between the two groups. CONCLUSIONS: The disc height and lumbar lordosis were considerably reduced in the patients with retrolisthesis, especially compared to those patients with spondylolisthesis. Preoperative pain was higher for the retrolisthesis patients than for the spondylolithesis patients, but there was no significant difference.
Animals ; Follow-Up Studies ; Humans ; Lordosis ; Retrospective Studies ; Spine ; Spondylolisthesis* ; Zygapophyseal Joint

PURPOSE: To analyze the effect of clearing the protruding posterior femoral condyle from the femoral component (PFC: Posterior femoral clearance) on knee flexion in patients who underwent LCS(R) rotating platform TKA. MATERIALS AND METHODS: Twelve patients were male and one hundred seventy-eight patients were female. The patients were divided into the following two groups: Group A (62 patients 84 knees), TKA without PFC; and Group B (128 patients 182 knees), TKA with PFC. The clinical and radiology follow-up were carried out using the HSS score and tibiofemoral angle, and the possibility of squatting was evaluated in each group, respectively. RESULTS: The mean flexion contracture improved 10.8degrees in group A, and 10.3degrees in group B. The mean further flexion improved 13degrees in group A, and 24degrees in group B. The improvement of knee flexion with PFC showed statistical significance. The mean HSS knee scores improved 30.5 points in group A, and 36.3 points in group B. The improvement in the HSS knee score with PFC showed statistical significance. Squatting was possible 50.0% of group A, and 67.4% of group B. CONCLUSION: PFC is effective in increasing the level of knee flexion and improving the HSS score. PFC can be a good solution for high demand patients, particularly those from Asian countries.
Arthroplasty* ; Asian Continental Ancestry Group ; Contracture ; Female ; Follow-Up Studies ; Humans ; Knee Joint ; Knee* ; Male

PURPOSE: The authors evaluated the clinical and radiological short-term results of ceramic on ceramic articulation of cementless total hip arthroplasty. MATERIALS AND METHODS: One hundred fourteen patients, with a total of 130 hips were followed for more than 2 years after cementless total hip arthroplasty using ceramic on ceramic articulation (Lima. SPH-C2). The mean age was 58 years, and the mean follow-up period was 3.0 years. The Harris hip score and postoperative hip pain were analyzed clinically. The radiological results were assessed using various radiological indices such as subsidence, cup inclination angle, radiolucent line, endosteal new bone formation and osteolysis. RESULTS: At last follow-up, the average Harris hip score improved from 57.5 points preoperatively to 93 points postoperatively. There were 4 cases (3.0%) of significant hip pain. Radiologically, all stems demonstrated stable fixation. The inclination of the acetabular cup was significantly changed in 4 cases (3%), and was diagnosed as loosened. A radiolucent line was observed around the stem in 5 cases (3.8%), and around the cup in 7 cases (5.4%). Endosteal new bone formation was observed around the stem in 47 cases (36.2%), and around the cup in 52 cases (40.0%). Osteolysis was not observed around the stem and the cup. CONCLUSION: With a minimum follow-up of 2 years, ceramic on ceramic articulation hip arthroplasty demonstrated excellent results on the stem side. However, 4 cases (3.0%) of cup loosening suggest that there is a fixation problem due to the design of the cup.
Acetabulum ; Arthroplasty ; Arthroplasty, Replacement, Hip* ; Ceramics* ; Follow-Up Studies ; Hip ; Humans ; Osteogenesis ; Osteolysis

STUDY DESIGN: This study is a prospective, clinical study for lumbar degenerative kyphosis. PURPOSE: To determine the factors affecting postoperative clinical outcomes in patients who undergo corrective osteotomy for lumbar degenerative kyphosis. OVERVIEW OF LITERATURE: Only a small number of studies have reported clinical results for surgery for lumbar degenerative kyphosis. There are almost no studies about prognostic factors that predict postoperative clinical results. METHODS: This study involved 25 patients who were diagnosed with lumbar degenerative kyphosis and who underwent corrective osteotomy following gait analysis. A pedicle subtraction osteotomy was done at the third lumbar vertebra (L 3). Regarding the fusion level, surgery was done within a range from T10 proximally to S1 distally. Of these, for rigid fixation of a distal part, an iliac screw was used. Pain was evaluated using a 10-point pain scale and a questionnaire about activities. We also evaluated cosmesis and subjective satisfaction using a modified version of the Scoliosis Research Society Outcome-22 (SRS-22) instrument. This assessment was done using a 5-point scale which was designed by us. We assigned patients to group A (good clinical outcomes) if their postoperative pain score was lower than 4 (of 10 points) and if scores indicating activity, cosmesis and subjective satisfaction were higher than 11 (of 15 points). All other patients were assigned to group B (poor clinical outcomes). RESULTS: Clinical outcomes were good in 64% of patients (16/25) and poor in 36% (9/25). Regarding cosmesis and subjective satisfaction, there were significant differences between the two groups. There were also significant differences in physical factors of individual patients such as body mass index (BMI): 23.78 +/- 2.79 in group A and 26.44 +/- 2.75 in group B. On gait analysis, there was a significant difference in the dynamic pelvic tilt: 7.5 +/- 3.3degrees in group A and 11.72 +/- 1.89degrees in group B. CONCLUSIONS: There is no correlation between preoperative degree of kyphotic deformity and clinical outcomes. The degree of anterior rotation of pelvic tilt does not change significantly; rather, compensatory mechanisms of the pelvis and BMI were found to have more influence. Because neither the degree of satisfaction with clinical outcomes nor the increased activity was relatively higher, a more sincere decision should be made before recommending corrective osteotomy for degenerative lumbar kyphosis.
Body Mass Index ; Congenital Abnormalities ; Gait ; Humans ; Kyphosis ; Osteotomy ; Pain, Postoperative ; Pelvis ; Prospective Studies ; Scoliosis ; Spine ; Surveys and Questionnaires