1.The Effect of H2-receptor in the Treatment of Peptic Ulcer.
Korean Journal of Gastrointestinal Endoscopy 1983;3(1):27-34
Treatment of peptic ulceration by suppression of gastric aeid, secretion with the histamine H,-receptor antagonist, cimetidine is now well established. Prior to the availability of ranitidine, cimetidine was the only histamine H2-receptor antagonist available for treatment of duodenal and gastric ulceration. The aim of this study was to compare the efficacy of ranitidine and cimetidine in accelerating the healing of duodenal ulcer. The therapeutic trials comparing ranitidine with cimetidine in a total of 44. out-patients with endoscopically diagnosed duodenal ulcer ivere entered into the study. 28 patients were treated with ranitidine 150mg twiee daily, and 16 patients with cimetidine 200 mg 4 times daily for 4 weeks. Overall endoscopic healing rates were 75%, on ranitidine and 64.3% on cimetidine, and so ranitidine appears to be slightly more effective than cimetidine although too small numbers af patients were studied to detcet any difference between drugs. Aa ranitidine is effective with administration twice daily, patient compliance may be better than with the 4 times daily treatment regimen adopted with cimetidine, though has not yet to be adequately demonstrated. There were no significant side-effects, either ranitidine or cimetidine, to the administration of the drug, except a case of dyspepsia on cimetidine regimen.
Cimetidine
;
Duodenal Ulcer
;
Dyspepsia
;
Histamine
;
Humans
;
Outpatients
;
Patient Compliance
;
Peptic Ulcer*
;
Ranitidine
;
Stomach Ulcer
2.Gynecologic Problems of the Infant and Young Child.
Journal of the Korean Medical Association 2000;43(10):983-991
3.Aging and Hormone Replacement Therapy.
Journal of the Korean Medical Association 2002;45(4):470-477
Three hormonal systems show decreasing circulating hormone concentrations during normal aging : (1) estrogen(in menopause), and testosterone (in andropause), (2) dehydroepiandrosterone and its sulfate (in adrenopause), and (3) the growth hormone/insulin-like growth factor 1 axis (in somatopause). Throughout the adult life, all physiological functions gradually decline. There is a diminishing capacity for cellular protein synthesis, an decline in immune function, an increase in fat mass, a loss of muscle mass and strength, and a decrease in bone mineral density. Physical changes during aging have been considered physiologic, but there is evidence that some of these changes are related to the decline in the hormonal activity. Various hormonal replacement strategies have been developed, but many of their aspects remain controversial, and increased blood hormone levels in aging individuals to those found during the mid-adult life have not been uniformly proven to be safe and of benefit.
Adult
;
Aging*
;
Bone Density
;
Dehydroepiandrosterone
;
Female
;
Hormone Replacement Therapy*
;
Humans
;
Menopause
;
Testosterone
4.The relationships among life events, family function and depression.
Journal of the Korean Academy of Family Medicine 1991;12(3):1-10
No abstract available.
Depression*
;
Humans
5.Using pig biliary system, in vivo propagation of Enterocytozoon bieneusi, an AIDS-related zoonotic pathogen.
Journal of Veterinary Science 2000;1(2):105-111
A microsporidian parasite Enterocytozoon bieneusi is the most common microorganism recognized in AIDS patients, and slow scientific progress is attributed to our inability to propagate the parasite. We report upon the development of a system of propagation using the pig biliary system. The parasite spores were continuously detected in the bile samples post onset of spore shedding in the gall bladder, which suggests that this organism maintain persistent infection in the biliary system and that the hepatobiliary tree may represent a reservoir of infection. In conclusion the biliary tree is an adequate niche for the propagation of E. bieneusi. This work has also resulted in the development of a procedure of ultrasound-guided cholecystocentesis for aspirating biles. This is a simple and non-surgical procedure, and creates no signs of clinical complications in the livers and the gall bladders after dozens of separate attempts. Thus, this is a very useful and safe technique for the aspiration of bile from live animals.
AIDS-Related Opportunistic Infections/*parasitology
;
Animals
;
Bile/parasitology
;
Biliary Tract/*parasitology
;
DNA, Protozoan/analysis
;
Disease Models, Animal
;
Enterocytozoon/*growth & development/physiology
;
Feces/parasitology
;
Gallbladder/parasitology/ultrasonography
;
Immunosuppression/veterinary
;
Microsporidiosis/*parasitology
;
Paracentesis/methods/veterinary
;
Polymerase Chain Reaction/veterinary
;
Specimen Handling/methods/veterinary
;
Spores, Protozoan/isolation & purification/physiology
;
Swine
6.Aging and Hormone Replacement Therapy.
Journal of the Korean Academy of Family Medicine 2003;24(7):593-598
No abstract available.
Aging*
;
Hormone Replacement Therapy*
7.Diagnosis of Colorectal Cancer.
Journal of the Korean Medical Association 2002;45(7):811-822
Recent development of dignostic tools such as video-endoscopy, chromoscopy, magnifying endoscopy, and endoscopic ultrasonography has made it possible to do the accurate staging of colorectal cancer. Dysplasia confined to mucosa or upper one-third of submucosa of rectal wall can be treated with mucosal resection or local resection for cure. The involvement of perirectal lymph node by cancers can be confirmed by endoscopic ultrasonography-guided fine needle aspiration cytology (EUS-FNA). Positron emission tomography is useful for the detection of recurrent and metastatic tumor after surgical resection. Colonoscopy is cost-effective for the screening of cancer, however, But the virtual colonoscopy with MR or CT can play the role of colonoscopy without risk. Stool DNA test is a promising tool. In addition to traditional diagnostic tools such as colonoscopy, CT and pathology, emerging knowledge from molecular biology of cancer gives information on predicts the prognosis of colorectal cancer patients.
Biopsy, Fine-Needle
;
Colonography, Computed Tomographic
;
Colonoscopy
;
Colorectal Neoplasms*
;
Diagnosis*
;
DNA
;
Endoscopy
;
Endosonography
;
Humans
;
Lymph Nodes
;
Mass Screening
;
Molecular Biology
;
Mucous Membrane
;
Pathology
;
Positron-Emission Tomography
;
Prognosis
8.Descriptive Study of Relationships between Depression, Family Support, and Rehabilitation-motivation in Patients with Cerebrovascular Accident.
Korean Journal of Rehabilitation Nursing 2004;7(2):188-196
PURPOSE: This study was conducted to identify relationships between depression, family support, and rehabilitation-motivation in patients with cerebrovascular accident. METHOD: The data were collected from 'S' hospital in Seoul from Feb. 1, 2004 to Apr. 30, 2004. The data were analyzed using a SPSS 10.0 program for descriptive statistics, Pearson correlation coefficients and stepwise multiple regression. RESULT: The results were as follows: The mean rehabilitation-motivation was 119.89, which was slightly high. The rehabilitation-motivation was influenced by religion, education level, occupation, economic status, treatment fee, duration of hospitalization, level of language ability and ADL. Rehabilitation-motivation has showed correlation with family support (r=.538, p=.000) and depression (r=-.417, p=.000). The variables related to rehabilitation-motivation were identified as family support, level of ADL, occupation, depression, and education level, using stepwise multiple regression. They were accounted for 57% of predictability of the rehabilitation-motivation, with the family support the highest at 29.3%. CONCLUSION: With increasing post stroke patients in Korea, we need to pay more attention to the rehabilitation of them. This study indicates that health professionals need to focus on the intervention especially in increasing family support and in decreasing depression of the patients with cerebrovascular accident.
Activities of Daily Living
;
Depression*
;
Education
;
Fees and Charges
;
Health Occupations
;
Hospitalization
;
Humans
;
Korea
;
Language
;
Occupations
;
Rehabilitation
;
Seoul
;
Stroke*
9.A Study on the Stress and Coping Patterns of Mothers with Cerebral Palsy Children.
Korean Journal of Child Health Nursing 1997;3(2):190-202
Mothers with cerebral palsy children have much stress that is related to the care of children with cerebral palsy and to other household duties, and this state of the mother has an effect on the cerebral palsy child and on other household member. Mothers in such stressful situations use various coping patterns. The purpose of this study was as follows : to develop instruments that can be used for measuring the stress and coping patterns of mothers with cerebral palsy children, and to test a hypothetical model on the relationship between the mother's stress, her coping patterns and the variable affecting the stress and coping patterns. The result of this study can be summarized as follows : 1. The stress scale was composed of 44 items and Cronbach's alpha was .94, and the coping pattern scale was composed of 19 items and Cronbach's alpha was .80. The mean score of stress scale was 136.12 out of a total of 220, and the mean score of the coping scale was 72.87 in a total of 95. 2. In test of the hypothetical model, it was found that extra-care demand, the support of the husband, the degree of handicap, health status and self-esteem had statistically significant influence on the mother's stress(r=.285,-.262,-.133,-.126). And the support of the husband, formal support, informal support, and economic status were found to have statistically significant influence on the mother's coping patterns(r=.412, .178, .178, .138).
Cerebral Palsy*
;
Child*
;
Family Characteristics
;
Humans
;
Mothers*
;
Spouses
;
Child Health
10.A Study on the Influences of Noise Induced Hearing Loss to the Blood Pressure.
Jong Hwa KIM ; Choong Rteol LEE
Korean Journal of Preventive Medicine 1987;20(2):205-214
For the purpose of evaluating the effect of noise induced hearing loss on the blood pressure, a cross-sectional study was conducted in 481 manufacturing industrial workers in Pusan area consisted of 275 workers from noisier plant (over 90 dB(A), high exposed group) and 206 workers from less noisy plant (below 85 dB(A), low exposed group) from April to December in 1985. The summarized results were as follows; 1) The degree of hearing loss according to the audible frequency was most notable in 4,000 Hz. 2) The prevalence of hypertension was 14.8% in total examined subjects. And also in 40 dB(A) hearing lost workers, there was no significant difference between high exposed group as 15.5% and low exposed group as 15.8%. 3) In 3 models analyzed by multiple regression technique to obtain the complexed extents of risk factors related to the diasatolic blood pressure, especially model iIII which contain age, body mass index, smoking, alcohol and family history of hypertension, duration of work, noise exposure level and degree of hearing loss in high exposed group was most remarkable compared to the others. 4) The most potential predictor related to the diatolic pressure in high exposed group was the degree of hearing loss. And the next were body mass index, familial history of hypertension and age in order. But in the case of low exposed group, the potential predictors were body mass index, age and familial history of hypertension.
Blood Pressure*
;
Body Mass Index
;
Busan
;
Cross-Sectional Studies
;
Hearing Loss*
;
Hearing*
;
Humans
;
Hypertension
;
Noise*
;
Plants
;
Prevalence
;
Risk Factors
;
Smoke
;
Smoking