BACKGROUND: Although the suicide rate in Korea is the highest in the world, only limited studies have been done on suicide and its associated factors. In this regard, we studied a conceptual model and the relationships and interactions of activity of daily living (ADL), social support, depression, and suicidal ideation among elderly women in Korea. METHODS: A cross-sectional descriptive study, subjects included 194 community-dwelling elderly women. Their ADL, multi-dimensional scale of perceived social support (MSPSS), depression, and suicidal ideation (SI) were examined. The t-test, ANOVA test, Pearson's correlation coefficient, multiple regression analysis, and structural equation modeling were utilized in data analysis. RESULTS: There were significant correlations between SI and economic status, social support, and depression. Depression was correlated with not only SI but also ADL (r=0.195, P=0.006) and social support (r=-0.337, P<0.001). Absolute fit indices demonstrated that the research model had a good model fit. There were significant factor loading values from depression to SI (standardized estimate=0.157, P=0.023) and from social support to SI (standardized estimate=-0.308, P<0.001). There were two indirect effects from social support to SI and from ADL to SI. The mediating factor of these two indirect effects was depression. CONCLUSIONS: Suicidal ideation in the elderly needs to be prevented; and more attention should be given to this end. Social support programs encouraging family participation are greatly effective in prevention of senior citizens' suicidal ideation.
Activities of Daily Living ; Aged* ; Depression ; Female ; Humans ; Korea ; Negotiating ; Statistics as Topic ; Suicidal Ideation* ; Suicide

Inositol 1,4,5-triphosphate(InsP,) is a second messenger for obilizing intracellular Cal'. It can be dephosphorylated by soluble and particulate forms on InsP, 5-phosphatase, or phosphorylated to produce inositol 1,3,4,5-tetrakisphosphate(InsP,) by InsP, 3-kinase. These enzymes represent possible targets for the regulation of the InsP,AnsP. signal. InsP, 3-kinase which catalyses th ATP-dependent phosphorylation of InsP, was purified from bovine brain tissue. All operation were carried out at 41C. Fresh tissure was homogenized and centrifuged. The supernatant was pooled. Proteins were precipitated from 10% polyethylene glycol, and suspended solution was applied to DEAE cellulose column for chromatography. As the result of above procedure, two isozymes of InsP, 3-kinase, I and U were obtained. Each isozyme was applied to Matriz green gel, Calmodulin-Affigel 15 column and subsequent phenyl-TSK HPLC column. Specific activites(SA) and fold of puriety were observed at each purification step of chromatography. At DEAE cellulose chromatography, SA were 1, 0.6 and 11, 4.8 nM/min/mg, and folds
Brain* ; Catalysis ; Chromatography ; Chromatography, DEAE-Cellulose ; Chromatography, High Pressure Liquid ; DEAE-Cellulose ; Inositol* ; Isoenzymes ; Phosphorylation ; Phosphotransferases* ; Polyethylene Glycols ; Second Messenger Systems

No abstract available.
Calcium* ; Phototherapy*

BACKGROUND: The purpose of this study was to examine the effects of a group intervention program on elderly people with chronic disease(s) living in the community. METHODS: This study was a nonequivalent control group pretest-posttest study. Participants were 101 elderly persons with hypertension and/or diabetes mellitus. The experimental group participated in an intervention program as a group while the control group participated individually, both for 16 weeks. The program involved health education, stretching exercises with thera-band and massage. The experimental group attended this program including group discussions while the control group attended the same program but without group discussions. Data were collected before and after the intervention, which went from September 1 to December 26, 2010. Data were analyzed using descriptive statistics, Spearman's rho and repeated measure analysis of covariance. RESULTS: There were significant differences between the groups for depression (F=49.756, P<0.001) and quality of life (F=7.289, P=0.008) after the intervention program. CONCLUSIONS: Our results indicate that intervention programs with a group approach are more effective than an individual approach for community-dwelling elderly with chronic disease. Therefore, a group approach should be considered when planning programs for elders in the community.
Aged ; Chronic Disease ; Depression ; Diabetes Mellitus ; Exercise ; Health Education ; Humans ; Hypertension ; Massage ; Quality of Life

The diagnosis and treatment of avascular necrosis of femoral head advanced, after Freud issued examples of bilateral avascular necrosis of femoral head (AVN) in 1926. But still not fixed in treatment and diagnosis. Recently early diagnosis and treatment produced good result. Whole body bone scan, intraosseous pressure mornitoring, intramedullary venography, C-T, or MRI, Selective femoral angiography also used in early diagnosis. Selective femoral angiography was performed for 56 patients, who has suspected as AVN by sumple X-ray and WBBS in order to estimate. How the femoral angiographic finding exist in AVN. In the control group femoral angiography performed to 5 person with normal stage of clinical and radiologic finding. So the result are as following l. All cases in the control group were not observed terminal branch of superior and inferior capslar branch. 2. In AVN the alteration of vasculature appeared 22 patients among 56 patient. 3. The altered vasculature presented 87.5% in traumatic group and 31.5% in nontraumatic group. 4. Collateral circulation was 22.2% in the cases of patients under 6 moths of the time interual between etiological events and clinical symptoms, 89.5% over 6 months. 5. Collateral circulation received 86.8% from inferior gluteal artery two cases from superior gluteal artery, and three cases form obturator artery. 6. Clinical tolerance was supposed to in well developed collateral circulation. According to the above results, Vascular alteraion were noted very much in traumatic group and development of collateral circulation were related promote clinical tolerance. Selective femoral angiography was not effective to assist early diagnosis and treatment of AVN for it could not detect terminal branch of superior and inferior capsular artery that reflected intraossous vasculsture. We need the new nethod of angoigraphy in order to early diagnosis.
Angiography ; Arteries ; Collateral Circulation ; Diagnosis ; Early Diagnosis ; Head ; Hip ; Humans ; Magnetic Resonance Imaging ; Moths ; Necrosis ; Phlebography

To investigate the effect of hyperoxia on EKG findings and to evaluate the applicability of EKG as noninvasive monitoring index of oxygen toxicity, 38 rabbits were continuously exposed to 6 different conditions-3 hyperbaric oxygenations (HBO-2.5, 3.5 and 5ATA, 100% O2), normobaric oxygenation (NBO, 100% O2), hyperbaric aeration (HBA-5ATA, 21% O2) and normobaric aeration (NBA, 21% O2)-for 120 minutes and their EKG and time to dyspnea and convulsion were recorded. Dyspnea and death were observed in exposure conditions of HBO-3.5 and HBO-5 (Positive rate of dyspnea; 10%, 100%, death; 10%, 25%, respectively) only, and convulsion in 4 oxygenation groups (NBO; 20%, HBO-2.5; 20%, HBO-3.5; 20%, HBO-5; 88%). Abnormal EKG findings included arrhythmia and ST-T changes and the incidences was increasing with doses(partial pressure of oxygen). In addition to EKG change, findings observed during exosure were dyspnea and convulsion in the order of appearence and when non specific ST-T change was accepted as positive (abnormal) finding, the frequency of abnormal EKG was statistically significant(p<0.01), but when it was excluded from positive results, the frequency of EKG change was not significant(p>0.05). These results suggest that the effect of hyperoxia on heart is myocardial ischemia and arrhythmia, that oxygenation more than 3.5ATA causes myocardial damage in 120 minutes exposure, and that EKG is valuable as monitoring index of oxygen toxicity.
Arrhythmias, Cardiac ; Dyspnea ; Electrocardiography* ; Heart ; Hyperbaric Oxygenation ; Hyperoxia* ; Incidence ; Myocardial Ischemia ; Oxygen ; Rabbits* ; Seizures

No abstract available.
Electrocardiography* ; Hyperbaric Oxygenation*

No abstract available.
Carcinoma, Hepatocellular*

PURPOSE: The purpose of this study was to analyze the relation between sex perception, sexual life satisfaction, and life satisfaction of the elderly. METHODS: The respondents were 227 elders aged over 65. Data were collected from February 10 to December 15, 2007 by interviews and questionnaires. RESULTS: Of the respondents, 18.8% still had sex life and 25.5% wanted to have a date. The main reason to have a date was to relieve loneliness, and the percentage of those who wanted a date was 58.3. The perception level of sex life was 2.27 (men: 2.51, women: 2.14), the satisfaction level of sex life was 2.74 (men: 2.89, women: 2.64), and the level of life satisfaction was 2.98 (men: 3.10, women: 2.92). There was a positive correlation between the perception level of sex life and the satisfaction level of sex life; a positive correlation between the satisfaction level of sex life and the level of life satisfaction; and no correlation between the perception level of sex life and the level of life satisfaction. CONCLUSION: This study provides a base supporting the usefulness of various nursing intervention programs to enhance the quality of life through making elderly people have a positive perception of sex life.
Aged* ; Surveys and Questionnaires ; Female ; Humans ; Loneliness ; Nursing ; Quality of Life ; Sexuality

No abstract available.
Animals ; Calcitonin* ; Female ; Osteoporosis* ; Ovariectomy* ; Rats* ; Tamoxifen*