1.A Study on Distribution of Lactic Dehydrogenase Isozyme in the Cortex and the Medulla of the Rabbit Kidney.
Korean Journal of Urology 1969;10(2):47-56
1. Using the kidney of the rabbit weighing approximately 1.5kg the LDH isozymes, LDH-l through 5, were analyzed on the acetate strip by electrophoresis and it was found that the LDH-3 was the least active isozyme followed by the LDH-2, -4, -1, and -5 in increasing order of activity both in that cortex and the medulla, showing a specific distribution pattern in the two tissues. 2. The difference in the isozymic distribution pattern between the cortex and the medulla was confirmed by separating the H-and M-LDH by DEAE-cellulose, the ratio of M-/H-LDH being l. 441t the medulla and 3. O3 in the cortex, showing more active anaerobic metabolism in the latter than in the former. 3. The total activity of LDH in the 20% homogenate of the total kidney tissue was 10. 55 units/ml the cortical 2.98 units/ml. and the medullary 7. 37 unite/ml. 4. In the unilaterally nephrectomized rabbit. the cortex of the remaining kidney showed increased activities of both H- and M-LDH, but the medullary H-LDH decreased, resulting in increases of the ratio M-,H-LDH both in the cortex and in the medulla 5. In the unilaterally pedicle-clamped rabbit, LDH of the clamped kidney medulla decreased while that of the cortex increased, and LDH of the unclamped kidney showed elevated activity both in the cortex and in the medulla, yielding an increase in the ratio of M-/H-LDH. 6. The specific difference in distribution pattern of LDH igozymes between the cortex and the medulla of the rabbit kidney and an increase of the ratio of M-/H.LDH resulting from functional compensation following unilateral nephrectomy or pedicle clamping have been briefly discussed.
Compensation and Redress
;
Constriction
;
DEAE-Cellulose
;
Electrophoresis
;
Isoenzymes
;
Kidney Medulla
;
Kidney*
;
Metabolism
;
Nephrectomy
;
Oxidoreductases*
2.Current Antiviral Therapy of Chronic Hepatitis B and C.
Journal of the Korean Medical Association 1999;42(9):898-906
No abstract available.
Hepatitis B, Chronic*
;
Hepatitis, Chronic*
3.Lamivudine therapy for type B chronic hepatitis in Korea.
Korean Journal of Medicine 2000;58(4):374-377
No abstract available.
Hepatitis, Chronic*
;
Korea*
;
Lamivudine*
4.Preventin of Hepatitis B.
Journal of the Korean Pediatric Society 1983;26(5):421-427
No abstract available.
Hepatitis B*
;
Hepatitis*
5.Cause, evaluation and treatment of dementia: for primar care physician.
Journal of the Korean Academy of Family Medicine 2001;22(5):619-630
No abstract available.
Dementia*
6.A clinical report of 55 internal arteriovenous fistulas in 45 patients for 2 & 3/12 years in a general hospital: analysis of failure and reoperation.
Journal of the Korean Surgical Society 1992;43(6):880-887
No abstract available.
Arteriovenous Fistula*
;
Hospitals, General*
;
Humans
;
Reoperation*
7.Hypertension in the elderly.
Journal of the Korean Academy of Family Medicine 1999;20(4):309-313
No abstract available.
Aged*
;
Humans
;
Hypertension*
8.The Histological Change of the Fractured epiphyseal Plate of the Distal End of the Femur in the Growing Rabbit
The Journal of the Korean Orthopaedic Association 1976;11(2):301-306
The orthopaedic treatment regarding to the residual deformity secondary to epiphyseal plate injury is the most important thing. Author particularily interested in the microscopic finding upon the repair of damaged transepiphyseal fracture of the distal femoral end of growing rabbits. Experimentally this type of fracture is produced surgically and fixation is achieved by two Kirshner wires; one Kirshner wire is inserted obliquely through the metaphysis. A total of 10 growing rabbits were fed with normal diet, and each 5 rabbits were psacrified by 8 and 10 weeks after the surgical procedure respectively and histological change is examined. No rabbit had infection for those experiment. The results of observation were summarized as follows:1. The ruptured epiphyseal plate due to osteotomy through epiphyseal plate was found to be healed by new bone and fibrotic tissue, not by cartilage regeneration. 2. The epiphyseal plate in the small part of fracture fragments revealed as follows; a. The arrangement of cartilage zones revealed marked irregularity. b. The form and the character of cartilage cells revealed an abnormality such as the hyperophy or the atrophy of cells or both. c. The necrotic area revealed at the several places. d. The thickness of epiphyseal plate revealed more narrowing and irregularity. 3. The effect on the kirschner wires were seen as follows; a. There was no evidence of cartilage regeneration on the margin of the damaged epiphyseal plate. due to Kirschner-wire insertion b. The adjacent tissues around the both kirschner Wires revealed pretty heavy new bone formation.
Atrophy
;
Bone Wires
;
Cartilage
;
Congenital Abnormalities
;
Diet
;
Femur
;
Growth Plate
;
Osteogenesis
;
Osteotomy
;
Rabbits
;
Regeneration
9.Experimental Study on Changes in 99mTc-MDP uptake of the Tibia during Blood-Flow and Skeletal phases
The Journal of the Korean Orthopaedic Association 1986;21(2):191-196
The purpose of this study is to observe the changes in 99mTc-MDP uptake of the tibia during blood-flow and skeletal phases and determine the clear borderline between both phases. Serial 99mTc-MDP uptake measurements were performed, as control, in ten matured rabbits with skin incision only and in thirty matured rabbits with fractures of middle and distal one-third of tibia, at ten minutes, thirty minutes, one hour, two hours and four hours after injection of bolus. A value in uptake ratio was calculated by measurements of 99mTc-MDP uptake at each observation time for analogous regions of normal and fractured tibia applied with or without tourniquet. The results obtained were as follows: 1. Group I (skin incision only in ten rabbits) 1) Without tourniquet, the mean 99mTc-MDP uptake ratio tibia was value of 1.05 at ten minutes, 0.97 at thirty minutes, 0.99 at one hour, 1.01 at two hours, 0.97 at three hours and 1.08 at four hours. 2) With tourniquet, the mean 99mTc-MDP uptake ratio of tibia was value of 0.61 at ten minutes, 0.64 at thirty minutes, 0.76 at one hour, 0.98 at two hours, 0.94 at three hours and 1.05 at four hours. 2. Group II (fracture with K-wire fixation in twenty rabbits) 1) Without tourniquet, the mean 99mTc-MDP uptake of tibia was value of 0.73 at ten minutes and 0.80 at two hours. 2) With tourniquet, the mean 99mTc-MDP uptake ratio of tibia was value of 0.45 at ten minutes and 0.76 at two hours. 3) There were no significant change of the 99mTc-MDP uptake ratio in two to four hours after fracture whether the tourniquet was applied on or not. 3. In cases with tourniquet application, there were no significant changes of 99mTc-MDP uptake ratio during two to four hours in group I anda II. This experiments suggest the optimal time for evaluation of the skeletal phase is in two hours following the injection of bolus (99mTc-MDP).
Rabbits
;
Skin
;
Technetium Tc 99m Medronate
;
Tibia
;
Tourniquets
10.ABO Gene Frequency in ABO Hemolytic Disease of Newborn.
Journal of the Korean Pediatric Society 1988;31(9):1105-1113
No abstract available.
Erythroblastosis, Fetal*
;
Gene Frequency*
;
Infant, Newborn