A case of gastric duplication associated with marked atypism in an adult is reported. The patient was a 62-year-old woman presenting a mass in left upper quadrant of abdomen. The mass was a closed gastric cyst located in the greater curvature, measuring 11 9 cm in diameter. The cyst had common muscular layer with stomach. It showed gray-white firm cystic wall with yellowish brown soft necrotic tissue. Microscopically, the cyst was lined by columnar mucin-secreting epithelium having marked cellular atypism. The cyst wall was supported by layers of smooth muscle, accompanied with severe fibrosis and chronic inflammation.
Abdomen ; Adult ; Epithelium ; Female ; Fibrosis ; Humans ; Inflammation ; Middle Aged ; Muscle, Smooth ; Stomach

A clinical and statistical study was done for 123 patients with histologically proven colorectal malignant tumor from 1983 to 1986 at the department of anatomical pathology. Yeungnam University Hospital. The results were as follows: 1. Ratio between male and female was 1.6:1 and incidence was most prevalent in 7th decades comprising 29.3%. 2. Location of tumor was the most frequent in rectum (65%). 3. Frequent symptoms and signs in case of right colon were pain, abdominal mass and bowel habit change. In left colon, they were pain, bowel habit change and bloody stool or melena. In rectum, they were bloody stool or melena, bowel habit change and pain. 4. Duration of symptom was 1 to 3 months (33.3%). 5. The most frequent histological type was adenocarcinoma (82.9%). 6. According to Duke's classification, 32.9% of the tumor were stage C2. 7. Operative procedures were Mile's operation (47.0%), right hemicolectomy (19.8%), and lower anterior resection (11.7%). 8. Polyps were the most frequent associated disease. 9. The most common complication was wound infection (11.1%).
Abdominal Pain ; Adenocarcinoma ; Classification ; Colon ; Daegu* ; Female ; Humans ; Incidence ; Male ; Melena ; Pathology ; Polyps ; Rectum ; Statistics as Topic ; Surgical Procedures, Operative ; Wound Infection

Carcinoid tumors are arisen from enterochromaffin cells, which are scattered throughout the body but occur primarily in the submucosa of the intestine and brpnchi. Carcinoid tumors synthesises numerous bioactive amines such as serotonin, and cause the carcinoid syndrome. Rectal carcinoids present as asymptomatic submucosal nodules less than 2cm in size. In contrast to other carcinoid tumors, distant metastasis are rare(less than 15%). Malignant potential is seen almost exclusively in patients with tumors larger than 2cm. Transanal local excision suffices for tumors less than 2cm, with radical surgery reserved only for larger tumors and those with histological evidence of invasion of the muscularis propria. I have experienced two cases of rectal carcinoid tumors less than 2cm, which do not invade the muscular wall of the rectum. These carcinoids were treated with endoscopic polypectomy.
Amines ; Carcinoid Tumor* ; Enterochromaffin Cells ; Humans ; Intestines ; Neoplasm Metastasis ; Rectum* ; Serotonin

No abstract available.

Necrotizing lymphadenitis was first recognised as a self-limiting lymphadenitis by Japanese workers in 1972. It is a distinct clinicopathologic entity, but can be mistaken as malignant lymphoma. We have studied clinicopathologic features in 15 cases of necrotizing lymphadenitis. This disease occurs predominantly in young adult. Male-female ratio is 2 : 1. The commonest presentation is lateral cervical lymphadenopathy. Pain, tenderness, and fever can be seen. Biopsy of the lymph nodes from all patients demonstrates the characteristic histologic features : multifocal, relatively circumscribed nodules in the cortex and/or paracortex, consisting of a mixture of activated large lymphoid cells, histiocytes and Small lymphocytes. Numerous karyorrhetic debris are present. Neutrophils and plasma cells are strikingly absent.
Asian Continental Ancestry Group ; Biopsy ; Fever ; Histiocytes ; Humans ; Lymph Nodes ; Lymphadenitis* ; Lymphatic Diseases ; Lymphocytes ; Lymphoma ; Neutrophils ; Plasma Cells ; Young Adult

For the more practical and convenient application of the Tzanck test, we evaluated several staining methods and cytological findings 98 cases of vesicobullous skin diseases. Fixation by air-drying of specimen aad modified Giemsa staining method were thought to be the most appropriate procedure in clinical use. The disease studied were chickenpox, herpes zoster & simplex, contact dermatitis, Id reaction, tinea pedis, urticaria pigmentosa, incontinentia pigmenti, farnilial benign pemphigus, hand-foot-mouth disease, erytherna multiforme, toxic epiderrzal necrolysis, fixed drug eruption, and septic vesicle. Among these, herpes and chickenpox vesicles shawed the most characteristic and specific findings. And degenerating giant cell could be added as an useful diagnostic marker for these diseases in relatively old lesions. In the other diseases, cytological findings were neither charcteristic nor specific. But these findings suggested the possibility of picking up useful findings by more elaborated study including more large number of cases.
Azure Stains ; Chickenpox ; Dermatitis, Contact ; Drug Eruptions ; Giant Cells ; Herpes Zoster ; Incontinentia Pigmenti ; Pemphigus ; Skin Diseases* ; Skin* ; Tinea Pedis ; Urticaria Pigmentosa

Utrasonic evaluation has been suggested as a screening method for early ovarian cancer. This study was designed to evaluate the aceuracy of pelvic ultraesound to measure the ovarian volume as the preliminary study. The ovarian volume me ured. by ultrasound was compared with findings at. surgery. Subjects far this investigation were 25 menstruating patients and 12 climacteric patients who were scheduled for gynecologic surgery chiefly unrelated to adnexal masses. The mean nf ovarian volume with menstruating patients was 5.7+/-5.9cm3 and that of climacteric patients was 2.5+/-l.3cm3(P<0.01). The eorrelation coefficient between the ovarian volurne measurement made by two examiners was 0.80. The correlation coeffieient between the ovarian volume measured by transvaginai ultrasonography and ovarian volume at laparotomy was 0. 37 and poor, The ll ovaries(52%) among the 24 ovaries of 12 climacteric tients were not visualized. So, this study suggested that the ovarian volume measurements af the postmenopauml by transvaginal ultrasonograpy was not simple and demanded the skill and laboraus training.
Climacteric ; Female ; Gynecologic Surgical Procedures ; Humans ; Laparotomy ; Mass Screening* ; Ovarian Neoplasms* ; Ovary ; Ultrasonography

A meta-analysis of 13 quasi-experimental studies was conducted to determine the effect of various nursing interventions applied to surgery patients. The studies were selected from dissertations done between 1982 to 1996 and had randomized or nonequivalent control groups in a pretest-post test design. The studies were classified according to three criteria : 1) types of surgery 2) types of nursing interventions 3) types of respondent variables. The following analysis was done : 1) Determination of usefulness of nursing interventions for surgery patients. 2) The magnitude of effect for each study was tested for different types of surgery, nursing interventions and outcome variables. 3) For a group of homogenious studies, the weighted mean effect size and standard error were estimated. Some findings are summarized as follows : Nursing interventions on relaxation effect applied to surgery patients have resulted in a significant effect size on pain, anxiety, and BP stabilization. Relaxation and music therapy were more effective on surgery patients than either education, heat therapy, or purposeful touch. It was impossible to identify which type of surgery was more effected by these interventions. On the basis of these findings, the following recommendations were made : 1) Many studies on the same kind of intervention applied to similar surgery patients should be accumulated continuously to identify factors that affect the effect size. 2) The detailed explanation of research process, such as, assignment method to experimental and control groups, starting points, duration and frequency of nursing interventions, and estimation of the outcome variables should be described in orther to be utilized for further research and practice.
Anxiety ; Education ; Hot Temperature ; Humans ; Music Therapy ; Nursing* ; Relaxation ; Surveys and Questionnaires

Although causative factors are not completely defined, carcinogenesis of colorectal cancer is attributed to multiple genetic alterations. The abnormal expressions of oncogenes are regarded to be responsible for the production of malignant phenotype, subsequent invasion and metastasis. From 63 surgically resectable colorectal adenocarcinoma patients, expression of oncogenes in colorectal cancer tissue was evaluated with immunohistochemical staining methods using monoclonal antibodies to products of the oncogenes. To evaluate the possibility of oncogenes as a prognostic factor, we studied the relationship between the expression of oncogenes and the clinicopathologic findings which are well known prognostic factors. Rates of expression in colorectal cancer tissue were 27% for c-myc, 74.6% for c-Ha-ras and 77.8% for c-erbB-2 oncogenes. The positive rate of c-erbB-2 oncogene was higher in the well differentiated group than in the poorly differentiated group. The rates of expression of c-myc and c-Ha-ras oncogenes were significantly correlated each other. Expression of these oncogenes in colorectal cancer were not correlated with the pathologic stage, location of cancer, DNA ploidy pattern and histologic differentiation except between c-erbB-2 and histologic differentiation. In conclusion, there seems to be a possibility that c-erbB-2 could be used as a prognostic factor of colorectal cancer. However, further and more intensive study seems to be required.
Adenocarcinoma ; Antibodies, Monoclonal ; Carcinogenesis ; Colorectal Neoplasms* ; DNA ; Humans ; Neoplasm Metastasis ; Oncogenes* ; Phenotype ; Ploidies

No abstract available.
Animals ; Dietary Fats* ; Rats*