1.Clinical Effect of Transurethral Needle Ablation (TUNA) in Durg Refractory Chronic Nonbacterial Prostatitis : Initial Experinece.
Phil Bum JUNG ; Jae Hoon WHANG ; Jeong Gu LEE
Korean Journal of Urology 2000;41(12):1490-1494
No abstract available.
Needles*
;
Prostatitis*
2.A case of serous surface papillary carcinoma.
In Gu WHANG ; Hak Bum SEO ; Young Tae KIM ; Kyu Wan LEE ; In Sun KIM
Korean Journal of Obstetrics and Gynecology 1992;35(4):613-617
No abstract available.
Carcinoma, Papillary*
3.Gamma knife radiosurgery for malignant tumors.
Journal of Korean Medical Science 1995;10(5):379-387
Between May 1990, and June 1994, 79 patients with malignant tumors were treated radiosurgically using a Leksell gamma unit at Asan Medical Center. Of these patients, 57 were metastatic brain tumor, 12 were glioblastoma multiforme (GM), 4 were primitive neuroectodermal tumor, 3 were malignant germ cell tumor, 2 were recurrent lymphoma, and 1 was adenoid cystic carcinoma of the orbit. Among 57 patients with metastatic tumors, 28 patients harboring 60 tumors were followed clinically and radiographically. The median marginal dose for these tumors was 30 Gy and the median survival rate was 15 months. Twenty-one tumors disappeared and 32 tumors decreased in size during 2 to 6 months after radiosurgery on computed tomographic or magnetic resonance imaging scans. All 12 patients with GM were treated with conventional radiation (6,240 approximately 6,500 cGy) after surgical resection or biopsy prior to radiosurgery (13 approximately 15 Gy to margin). The results were varied. Radiosurgical treatment of two recurrent lymphomas and three recurrent mixed germ cell tumors after radiation and chemotherapy provided rapid clinical improvement with disappearance of the tumor. However, new lesions appeared in two lymphomas and one mixed germ cell tumor within 3 to 4 months. One patient with adenoid cystic carcinoma of the orbit, who was treated radiosurgically prior to resection, is alive without recurrence 31 months after the treatment. Gamma knife radiosurgery appears to be the best alternative method to surgical excision plus radiation therapy for single and multiple cerebral metastases. It also provides rapid palliation of symptoms due to recurrent malignant tumors. And it may have an adjuvant role in the treatment of some tumors delaying local recurrence, if given prior to resection. However, the preliminary results for the malignant gliomas were inconclusive.
Adult
;
Aged
;
Brain Neoplasms/secondary/*surgery
;
Female
;
Follow-Up Studies
;
Human
;
Male
;
Middle Age
;
*Radiosurgery
4.Empyema Thoracis Resulting from Migrated Acupuncture Needle: Two Cases.
Eun Gu WHANG ; Bum Shik KIM ; Kyu Suk CHO ; Joo Chul PARK
The Korean Journal of Thoracic and Cardiovascular Surgery 2001;34(1):101-103
We experienced two cases of empyema thoracis which were caused by migrated acupuncture needle. Two patients were transferred from oriental hospitals because of dyspnea and high fever. Simple chest radiography and computed tomography(CT) of the two cases on admission showed haziness of the lower lung and acupuncture needles in the lung and pleural cavity on admission. Removal of acupuncture needles and decortication were performed.
Acupuncture*
;
Dyspnea
;
Empyema*
;
Fever
;
Humans
;
Lung
;
Needles*
;
Pleural Cavity
;
Radiography
;
Thorax
5.The Influence of Labor and Cesarean Section in Uroflowmetry.
Youn Seok CHOI ; Soon Gu WHANG ; Chang Kyu HUH ; Chang Youn KIM ; Tae Sung LEE ; Duk Yoon KIM
Korean Journal of Obstetrics and Gynecology 2003;46(9):1674-1679
OBJECTIVE: The purpose of this study is to evaluate the uroflow parameters of the pregnant women before delivery and immediate postpartum period. METHODS: Forty four patients delivered by spontaneous vaginal delivery (NVD group) and 46 patients by Cesarean section (C/SEC group) and 28 non-pregnant young women (Control group) were included in this study. Uroflow were checked 1 day before and 2 days after delivery by Jupiter 8000 (FM Wiest(R)) uroflowmetry. Mean value of the uroflow parameters in each group was compared using ANOVA t-test. For continuous data, linear associations with each of the uroflow parameters were assessed using a Pearson correlation coefficient. RESULTS: Maximal (18.48+/-5.21 mL/sec) and mean flow rate (9.45+/-3.73 mL/sec) of pregnant women were lower than control group (22.75+/-5.14 mL/sec), and were not changed after delivery (18.79+/-6.03 mL/ sec). Total flow time of pregnant woman (14.06+/-6.09 sec) was longer than control group (8.05+/-5.32 sec) before delivery, and increased after delivery especially after cesarean delivery. Time to peak flow of pregnant women (8.44+/-9.48 sec) was shorter than control group (16.33+/-6.11 sec) before delivery, and was similar to control group after delivery. Total voided volume (121.39+/-50.17 mL) was less than control group before delivery, and was increased after delivery (246.77+/-127.42 mL). Total voided volume after delivery was not different with control group statistically. CONCLUSION: There was no statistically differences before and after delivery in maximal flow rate, but was lower than non-pregnant women. Total flow time was much prolonged after delivery, especially after cesarean delivery. Time to peak flow and voided volume were restored to levels of non-pregnant women after delivery.
Cesarean Section*
;
Female
;
Humans
;
Postpartum Period
;
Pregnancy
;
Pregnant Women
6.Textual criticized and collated on names and breeds of Tibetan medicine "Dida".
Guoyue ZHONG ; Rui GU ; Huarong ZHOU ; Changhua WHANG ; Jifeng ZHAO ; Xiang LIU ; Yongzhong ZEWENG ; Songyun QIN
China Journal of Chinese Materia Medica 2009;34(23):3139-3144
Integrating textual criticism literatures with field survey, the name, classification and botanical originals of breeds of Tibetan medicine "Dida" were discussed in this paper. The results showed that it's very intricate and confusion in the names, breeds and botanical originals of "Dida", and those were the key restricting factors resulting in shortfall and difficult formulation in quality standard of "Dida". The similar situations are existing universally in ethnodrugs, and reflecting the necessity and urgency to collate ethnodrug breeds. On the other hand, Because of the morphologic description on the botanical origins of drug was often simple in the ancient literatures, and in most cases, the botanical origins of the drug were difficult to identify accurately on the basis of the literatures. So, in the collating the breeds, it's necessary to follow the principle of "according to the ancient literatures but no rigidly", and to pay attention to the historical vicissitude of the drug breeds and origins, and the survey of present resources and clinical using, draw actively on outcome of chemical and biological active researches. That inherited the characteristics and advantages of ethnodrugs, and promoted them them modernization.
Breeding
;
History, Ancient
;
Humans
;
Medicine in Literature
;
Medicine, Tibetan Traditional
;
history
;
Plant Extracts
;
analysis
;
Plants, Medicinal
;
chemistry
;
classification
;
Terminology as Topic
;
Tibet
7.Experience of Splenic Artery Aneurysms.
Yong Geul JOH ; Suk In JUNG ; Jun Won UM ; Sung Soo JUN ; In Gu KANG ; Young Ju KIM ; Sang Yong CHOI ; Cheung Wung WHANG
Journal of the Korean Society for Vascular Surgery 2000;16(1):54-60
PURPOSE: Splenic artery aneurysm is uncommon, but the increased frequency in use of arteriography, computed tomography, and ultrasonography has resulted in increasing clinical recognition of these lesions. This paper relates our experience in the outcome and management of aneurysms of the splenic artery. METHODS: From January 1992 to October 1999, 12 patients were diagnosed with splenic artery aneurysms. They were retrospectively analyzed. RESULTS: The male to female ratio was 1:4 and the mean age was 46.3 years. The mean of pregnancy history of all women was 3.0 and there were no pregnant women during operation. The associated diseases that might have caused the aneurysms were pancreatitis in 5 patients, portal hypertension in 1, operative trauma in 1, and ill defined pathogenesis in 5 patients. The size of the aneurysms was larger than 2 cm in all patients. The splenic artery aneurysms was located at distal in 9 patients, mid in 1, and proximal in 2 patients. 7 patients were treated surgically (aneurysmectomy without splenectomy in 1 patient, aneurysmectomy with splenectomy in 6 patients). Transcatheter embolization was used in 4 patients. One of them was treated with distal pancreatectomy after two months because of pancreatic pseudocyst. One patient without treatment died 2 years after diagnosis. CONCLUSION: Although surgery remains necessary in splenic artery aneurysms larger than 2 cm, transcatheter embolization is effective in initial treatment of the high risk group in splenic artery aneurysms.
Aneurysm*
;
Angiography
;
Diagnosis
;
Female
;
Humans
;
Hypertension, Portal
;
Male
;
Pancreatectomy
;
Pancreatic Pseudocyst
;
Pancreatitis
;
Pregnant Women
;
Reproductive History
;
Retrospective Studies
;
Splenectomy
;
Splenic Artery*
;
Ultrasonography
8.A Case of Cauda Equina Schwannoma Presenting as Normal Pressure Hydrocephalus.
Yong Jin CHO ; Won Kyoo KIM ; Choong Jin WHANG ; Keun Sik HONG
Journal of the Korean Neurological Association 2003;21(2):213-216
A 61-year-old man presented with cognitive dysfunction and an 8-month history of progressive gait disturbance. Brain MRI revealed communicating hydrocephalus. Under the impression of normal pressure hydrocephalus, cerebrospinal fluid (CSF) study was done and showed unusually increased opening pressure (40 cm H2O) and protein concentration (650 mg/dl). Spine MRI was performed to rule out the possibility of intraspinal tumor. It revealed cauda equina mass, which was confirmed to be schwannoma pathologically. Intraspinal tumor should be suspected in patients with abnormally increased CSF opening pressure and/or CSF protein who presented as normal pressure hydrocephalus.
Brain
;
Cauda Equina*
;
Cerebrospinal Fluid
;
Gait
;
Humans
;
Hydrocephalus
;
Hydrocephalus, Normal Pressure*
;
Magnetic Resonance Imaging
;
Middle Aged
;
Neurilemmoma*
;
Spine
9.Dietary source of vitamin B12 intake and vitamin B12 status in female elderly Koreans aged 85 and older living in rural area.
Chung Shil KWAK ; Mee Sook LEE ; Hae Jeung LEE ; Jin Yong WHANG ; Sang Chul PARK
Nutrition Research and Practice 2010;4(3):229-234
Recently, we found and analyzed vitamin B12 in some Korean traditional plant foods which had not reported, yet. This study was to investigate vitamin B12 intake and its dietary sources and the vitamin B12 status in the very old elderly Koreans. We measured serum vitamin B12 level and estimated the amounts of vitamin B12 intake from different dietary sources in female elderly Koreans aged 85 and over who had consumed a relatively low animal traditional diet for the whole life. The average age of the subjects (n = 127) was 98.0 years (85-108 years). The assessment on energy and nutrient intake involved a one-day 24-hour recall, and serum vitamin B12 concentration was measured by radioimmunoassay. Overall diet pattern was not different between the 85-99 yr-old group and centenarians, except centenarians were taking more dairy product. The average ratio of plant food to animal food consumption was 87.5:12.5 in weight. The average vitamin B12 intake of our subjects was 3.2 microg/day, and 52.7% of subjects consumed under estimated average requirement, 2.0 microg/day. On dietary source, 67.3% of dietary vitamin B12 was from meat, eggs and fishes and 30.6% was from plant foods, such as soybean-fermented foods, seaweeds, and kimchi. The average serum vitamin B12 concentration was 450.5 pg/mL, and low serum vitamin B12 (< 200 pg/mL) was found in 9.6% of subjects. Dietary vitamin B12 intake was significantly lower in subjects with low serum vitamin B12 (0.79 microg/day) than those with normal serum vitamin B12 (3.47 microg/day). There were no significant difference in vitamin B12 intake and its dietary sources and serum vitamin B12 level between the 85-99 yr-old group and centenarians. In conclusion, several plant-origin foods including seaweed, soybean-fermented foods, and kimchi, may contribute significantly to good vitamin B12 status in very old elderly Koreans.
Aged
;
Aged, 80 and over
;
Animals
;
Dairy Products
;
Diet
;
Eggs
;
Female
;
Fishes
;
Humans
;
Meat
;
Ovum
;
Plants
;
Radioimmunoassay
;
Seaweed
;
Vitamin B 12
;
Vitamins
10.Clinical Analysis of Novalis Stereotactic Radiosurgery for Brain Metastases.
Hae Won GU ; Moon Jun SOHN ; Dong Joon LEE ; Hye Ran LEE ; Chae Heuck LEE ; C Jin WHANG
Journal of Korean Neurosurgical Society 2009;46(3):245-251
OBJECTIVE: The authors analyzed the effectiveness and therapeutic response of Novalis shaped beam radiosurgery for metastatic brain tumors, and the prognostic factors which influenced the outcome. METHODS: We performed a retrospective analysis of 106 patients who underwent 159 treatments for 640 metastatic brain lesions between January 2000 and April 2008. The pathologies of the primary tumor were mainly lung (45.3%), breast (18.2%) and GI tract (13.2%). We classified the patients using Radiation Therapy Oncology Group Recursive Partitioning Analysis (RPA) and then analyzed the survival and prognostic factors according to the Kaplan Meier method and univariate analysis. RESULTS: The overall median actuarial survival rate was 7.3 months from the time of first radiosurgery treatment while 1 and 2 year actuarial survival estimates were 31% and 14.4%, respectively. Median actuarial survival rates for RPA classes I, II, and III were 31.3 months, 7.5 months and 1.7 months, respectively. Patients' life spans, higher Karnofsky performance scores and age correlated closely with RPA classes. However, sex and the number of lesions were not found to be significantly associated with length of survival. CONCLUSION: This result suggests that Novalis radiosurgery can be a good treatment option for treatment of the patients with brain metastases.
Brain
;
Brain Neoplasms
;
Breast
;
Gastrointestinal Tract
;
Humans
;
Lung
;
Neoplasm Metastasis
;
Radiosurgery
;
Retrospective Studies
;
Survival Rate