The hemodynamic aspects of cerebral arteriovenous malformations(AVM) are currently the subject of increasing interest. Recently developed methods such as Doppler sonography, Xenon-enhanced Computed tomography Cerebral blood flow(CT CBF), single photon emission computed tomography(SPECT), and position emission tomography(PET) have promoted a more dynamic diagnostic and therapeutic approach to the complicated problem related to surgery of AVM. In this article, the literatures concerning the hemodynamics of cerebral AVM were reviewed.
Arteriovenous Malformations ; Hemodynamics* ; Intracranial Arteriovenous Malformations*

A 21-year-old Korean male was referred to our department in June, 1999 for the evaluation of extensive reddish patches and gray-bluish pigmentation since birth. Physical examination revealed two kinds of patches over the various parts of the body. Reddish patches suggesting nevus flammeus were located on the left side of face, chest, and both upper and lower extremities. Gray-bluish pigmented patches suggesting nevus of Ota were found on both the periorbital areas. A 0.5×0.6 cm erythematous papule was found on the right anterior chest. The results of its histopathologic examination were compatible with pyogenic granuloma. We made the diagnosis of phakomatosis pigmentovascularis associated with pyogenic granuloma as well as Sturge-Weber syndrome and Klippel-Trenanunay syndrome.
Diagnosis ; Granuloma, Pyogenic* ; Humans ; Klippel-Trenaunay-Weber Syndrome* ; Lower Extremity ; Male ; Neurocutaneous Syndromes* ; Nevus of Ota ; Parturition ; Physical Examination ; Pigmentation ; Port-Wine Stain ; Sturge-Weber Syndrome* ; Thorax ; Young Adult

No abstract available.
Microdialysis* ; Myocardium*

In mammal, lots of follicles start simultaneously their growth but only a few oocytes are ovulated in every sexual cycles. Most of matured and grown oocytes are destined to degenerate by atresia. However, the molecular and physiological mechanisms are not elucidated yet. The present study was designed to establish an induction method of follicular atresia with ketamine or pentobarbitone and evaluate the effect of these anesthetics on oocyte maturation and granulosa cell apoptosis of the mouse ovarian follicle. The percentages of degenerated oocyte and apoptotic granulosa cell in ketamine treated groups were significantly higher than that in controls (58.9% vs 33.5%, p<0.01, degeneration; 44.9% vs 26.6%, p<0.01, apotosis). Futhermore, it was revealed that the concentrations of progesterone in both groups were markedly higher than that in control. In conclusion, it is considered that ketamine induce an atresia as pentobarbitone, and may be useful for inducing follicular atresia.
Anesthetics ; Animals ; Apoptosis ; Female ; Follicular Atresia ; Granulosa Cells* ; Ketamine* ; Mammals ; Mice* ; Oocytes* ; Ovarian Follicle ; Ovary* ; Pentobarbital* ; Progesterone

No abstract available.
Laryngeal Neoplasms* ; Radiotherapy*

Tubular apocrine adenoma(TAA) is a rare benign neoplasm usually found on the scalp. It has been designated as an apocrine histogenesis on the basis of its ultrastructural characteristics, enzyme, and immunohistochemical phenotype. Histopathologically the neoplasm consists of tubules or cysts, which show signs of apocrine secretion and sometimes needs to be differentiated from papillary eccrine adenoma. We report a typical case of TAA on nostril which shows differentiation toward apocrine in nature.
Adenoma* ; Phenotype ; Scalp

No abstract available.
Hypopituitarism*

No abstract available.

Eosinophilic cellulitis is a rare dermatosis originally described by Wells as "recurrent granulomatous dermatitis with eosinophilia", then called Wells' syndrome. The etiology is unknown, although a hypersensitivity mechanism is suspected. Flame figures are considered as a characteristic histologic feature of Wells' syndrome. To clarify the nature of eosinophilic cellulitis and its flame figures, the authors have reviewed five cases of eosinophilic cellulitis with its clinical and histopathologic findings. Cutaneous lesions were variable in appearance and was confused with angioedema, urticarial vasculitis, erydiema multiforme, morphea or granuloma annulare. Microscopically, early lesions (2-7 days) showed diffuse dermal eosinophilic infiltration with widespread degranulation, sometimes extended into the underlying muscle. Subepidermal bulla was present in one case. Subsequently, granulomatous features with characteristic "flame figures" became apparent (several months). Collagen alteration by eosinophilic granules resulted in flame figure formation and a granulomatous response. In two patients, there were possible relationships between drug and flare-ups of eosinophilic cellulitis, but the others, no contributory precipitating factors were found. We think that eosinophilic cellulitis represents a severe anaphylactic hypersensitivity reaction to various stimuli showing characteristic histopathology with recurrent episodes and frequent hypereosinophilia in the peripheral blood.

Atypical condyloma is a variant of flat condyloma characterized by the presence of atypical koilocytes having large hyperchromatic, smudged and often bizarre nuclei. Atypical condyloma can be frequently misdiagnosed on cytologic smear and on tissue sections by its marked cellular atypia, as high grade dysplasia, in situ or even invasive squamous cell carcinoma. We described two cases of atypical condyloma of the female genital tract. The cytologic features and histologic changes were reminiscent of those of invasive squamous cell carcinoma and severe degree of dysplasia of the uterine cervix. The differential findings between atypical condyloma and squamous cell carcinoma were discussed in detail.
Female ; Humans