2.Immunohistochemical Study of bcl - 2 Expression in Basal Cell Carcinoma.
Korean Journal of Dermatology 1997;35(2):242-248
BACKGROUND: Basal cell carcinoma(BCC) is the most common tumor of light-skinned people. Most of them are relatively innocuous, but some may cause extensive tissue destruction, and result in death by local infiltration of vital structure or metastatic disease. The bcl-2 is a protooncogene involved in tumorigenesis by blocking apoptosis or programmed cell death. OBJECTIVE: To investigate whether there was a difference in bcl-2 expression in different histopathological types of BCC. Method: We performed immunohistochemical staining by using a monoclonal mouse anti-human bcl-2 oncoprotein in 28 BCC(nodular: 7 cases, micronodular; 3 cases, adenoid; 1 case, infiltrative; 9 cases, and mixed; 8 cases). Result: All 28 BCC expressed bcl-2, and the degree of staining was different according to histopathological types; poor prognostic micronodular(100%) and infiltrative(73.3%) types were relatively strong, and nodular(66.7% ) and adenoid(75.0%) types were moderate. Conclusion . These results suggest that the degree of bcl-2 expression in BCC seems to be dependent to the histopathological types together with clinical behavior.
Adenoids
;
Animals
;
Apoptosis
;
Carcinogenesis
;
Carcinoma, Basal Cell*
;
Cell Death
;
Mice
3.Le Fort III Advancement for the Correction of Crouzon's Disease.
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(4):590-596
Crouzon's disease, first described by Crouzon in 1912, is characterized by craniosynostosis, exorbitism and midface hypoplasia. As well, it has been known to be transmitted as an autosomal dominant trait. Clinically, Crouzon's disease not only has aesthetic problems, but also many functional disabilities, such as increased intracranial pressure, hydrocephalus, visual disturbance. difficulty in nasal breathing and malocclusion. The surgical correction of Crouzon's disease includes: 1) frontal bone advancement and release of the craniosynostosis; 2) correction of the midface retrusion; and 3) other ancillary procedures for better aesthetic results. The authors performed Le Fort III advancement for the correction of midface retrusion in 5 cases of Crouzon's disease. These advancements were performed at about the age of 15 in consideration of facial bone growth disturbance, psychosocial effects, and the recurrence of class III malocclusion after operation. The average advancement of the midface was 9. 2 mm. We experienced favorable aesthetic and functional results without severe complication in all cases or relapse of the advanced segment.
Craniofacial Dysostosis*
;
Craniosynostoses
;
Facial Bones
;
Frontal Bone
;
Hydrocephalus
;
Intracranial Pressure
;
Malocclusion
;
Recurrence
;
Respiration
4.An experimental study of tissue reaction of absorbable suture materials
Sun Chul SONG ; Kyung Wook KIM
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons 1991;13(4):381-390
No abstract available.
Sutures
5.Computed tomotgraphy in the preoperative evaluation of clinical stage I b-II a carcinoma of the cervix.
Man Chul PARK ; Joo Hyun NAM ; Won Sop OH ; Jwa Koo CHUNG ; Chul Sun CHOI
Korean Journal of Obstetrics and Gynecology 1993;36(7):1293-1299
No abstract available.
Cervix Uteri*
;
Female
6.Chest radiographic changes after lobactomy and pneumonectomy.
In Sup SONG ; Dong Chul JANG ; Seung Chul KIM ; Sun Dae SONG ; Kun Sang KIM
Journal of the Korean Radiological Society 1991;27(1):49-54
No abstract available.
Pneumonectomy*
;
Radiography, Thoracic*
;
Thorax*
7.A Case of Embryonal Carcinoma Developed in a Cryptorchid Testis.
Joon Chul SONG ; Won Sun LEE ; Dong Ik SUH
Korean Journal of Urology 1968;9(2):103-107
A case of testicular embryonal carcinoma developed in s cryptorchid testis is presented with a review of the literature. According to Campbell's series, the incidence of malignant cryptorchid testis was 11.6%. and his statistical evaluation was similar to Gilbert and Hamilton's series of 7,000 cases of testicular neoplasms where 840 tumors were developed in undescended testes(12%). Both authors agree that the chance of neoplastic development in a cryptorchid testis is approximately 48 times greater then that developing in a normally descended testis. Several cases of testicular tumor were reported sporadically in Korea, but malignant tumors in cryptorchism were rarely seen in the literatures Only two cases of malignant cryptorchid testis were already reported in Korea.
Carcinoma, Embryonal*
;
Cryptorchidism
;
Incidence
;
Korea
;
Male
;
Testicular Neoplasms
;
Testis*
8.Effects of Age and Left Ventricular Hypertrophy on Left Ventricular Diastolic Function in Normotensives and Hypertensives.
Dong Chul LEE ; Dong Sun HAN ; Won Sang YOO
Korean Circulation Journal 1991;21(1):92-99
Transmitral left ventricular diastolic inflow velocities determined by pulsed Doppler in 47 normotensives, 80 hypertensives and 44 age-matched hypertensives were measured to evaluate the effects of age and left ventricular hypertrophy on left ventricular diastolic fuction in normotensives and hypertensives. The results were as follows: 1) The peak E velocity in normotensives(77.82+/-13.53cm/sec) was significantly different from those of hyeprtensives(58.13+/-11.80cm, p<0.01) and age-matched hypertensives(59.31+/-10.94cm/sec, p<0.01). The peak E/A in normotensives(1.31+/-0.45) was significantly different from those of hypertensives(0.83+/-0.21,p<0.01) and age-matched hypertensives(0.83+/-0.20, p<0.01). 2)In normotensives, simple linear regression analysis revealed strong inverse correlations of peak E with age(r=-0.758, p<0.01), peak E/A with age(r=-0.748, p<0.01), but no significant correlation of peak E and peak E/A with LVMI(p>0.05). Stepwise regression analysis revealed that age was the most important correlate of peak E and peak E/A in normotensives(peak E: R
Heart Diseases
;
Hypertrophy, Left Ventricular*
;
Linear Models
9.Clinical study for prognostic factors in colorectal cancer.
Chul Kyoo LEE ; Nam Sun PAIK ; Dong Wook CHOI
Journal of the Korean Cancer Association 1991;23(3):619-629
No abstract available.
Colorectal Neoplasms*
10.Usefulness of Three - Dimensional CT Angiography as a Confirmatory Diagnostic Test for Scalp Pseudoaneurysms.
Soon Kwon KIM ; Sun Chul HWANG ; Bum Tae KIM
Korean Journal of Cerebrovascular Surgery 2010;12(2):87-90
OBJECTIVE: We report here on two cases of pseudoaneurysms that were diagnosed using computed tomographic angiography (CTA), with one arising in the superficial temporal artery and the other arising in the occipital artery. METHODS: Case 1: A 29-year-old man presented with a slow growing, pulsatile mass on the left side of his forehead following a blow from a fist 10 days earlier. CTA revealed an 11 x 8 x 11-mm oval pseudoaneurysm arising from the frontal branch of the left superficial temporal artery. Case 2 : A 36-year-old man presented with a pulsatile mass in the right suboccipital region that had been present for the past year. He had no history of direct trauma. CTA revealed a 15 x 8 x 13-mm oval dye-filled sac arising from the right occipital artery. RESULTS: Based on the CTA images, the parent arteries were exposed and ligated proximally and distally to the pseudoaneurysms and then they were completely excised. CONCLUSION: CTA is a minimally invasive technique for making the diagnosis of scalp pseudoaneurysms and CTA is also useful for the preoperative planning.
Adult
;
Aneurysm, False
;
Angiography
;
Arteries
;
Diagnostic Tests, Routine
;
Forehead
;
Humans
;
Parents
;
Scalp
;
Temporal Arteries