1.The Incidence of Dermographism in the General Population.
Seon Hoon KIM ; Jee Ho CHOI ; Hee Chul EUN
Korean Journal of Dermatology 1984;22(2):191-195
As the incidence of dermographism in our urticaria clinie is quite high comparing data in other country, we have tried to survey the incidence of ermographism in the general population of Korea using a dermographic tester designed by other author. Total 8g7 healthy persons were included in this study from March J98$ to .December 1983. The study result was summarized as follows, 1. Male to female ratio was 2. 5: 1 and the peak age of the subjects was third(47 8%), fourth and fith decades in ecreasing order, The overall incidence of dermographisrn from the pressure of 48ppg/cm was 4.4% and there were no significa.nt difference in the incidences between male(4, 2%) and female(4 7%) (p>0. 1), and between the different age groups(p>0 l)
Female
;
Humans
;
Incidence*
;
Korea
;
Male
;
Urticaria
2.Skin irritant potency of occupationally hazardous chemicals usingkeatinocyte culture model and blood flow measurement.
Hee Chul EUN ; Duk Kyu CHUN ; Seon Hoon KIM
Korean Journal of Occupational and Environmental Medicine 1991;3(2):145-152
No abstract available.
Hazardous Substances*
;
Occupations*
;
Skin*
3.Registration of Rho(D) negative blood donors.
Seon Ho LEE ; Young Chul OH ; Ki Hong KIM
Korean Journal of Blood Transfusion 1993;4(2):165-171
No abstract available.
Blood Donors*
;
Humans
4.Registration of Rho(D) negative blood donors.
Seon Ho LEE ; Young Chul OH ; Ki Hong KIM
Korean Journal of Blood Transfusion 1993;4(2):165-171
No abstract available.
Blood Donors*
;
Humans
5.Evaluation of sonographic and radiographic findings of pelvic masses
Hyo Seon CHUNG ; Chul Uk CHOI ; Yong Chul KIM ; Kyoung Ja SHIN ; Sang Chun LEE
Journal of the Korean Radiological Society 1985;21(5):826-833
Ultrasonographic and radiographic findings in 72 cases of pelvic masses which have been provedhistopathologically were analyzed. The results were as follows; 1. Among 72 cases, 28 cases were uterine massesand 44 cases were adnexal masses. 2. Pathologic accuracies of ultrasonographic diagnosis were 64.3% in uterinemasses, 70.5% in adnexal masses, and 68.1% in all pelvic masses. 3. Plain or IVP findings were not specific indiagnosis and showed secondary mass effects or functional disturbances. 4. Because of its high accuracy ofpathologic diagnosis and safety, ultrasonography can be regared as the most valuable and preferential study. Butin cases of cystic myomas, endometrioses, cystic missed abortions and huge masses, the accurate diagnoses weredifficult.
Abortion, Missed
;
Diagnosis
;
Endometriosis
;
Female
;
Myoma
;
Pregnancy
;
Ultrasonography
6.Transverse uterine incision closure: One versus Two layers.
Sang Hee LEE ; Yu Seon MIN ; Eun Hye LEE ; Hyun Chul KIM ; Chan LEE ; Myung Chul SHIN ; Jin Ho CHO
Korean Journal of Obstetrics and Gynecology 2000;43(3):368-374
OBJECTIVE: Closure of a low transverse cesarean incision with one layer and two layer, we compared operative time, hemostasis, blood loss and postoperative sonohysteroperitoneographic findings. Study design: At our hospital 103 women were randomized to closure of a low transverse cesarean incision with either one continuous layer of a locking No. 1 chromic suture or two continuous of No. 1 chromic suture with the first layer locked between Mar. 1, 1998 and Dec. 31, 1998. After three months later, sonhysteroperitoneography was taken and then we evaluated uterus indirectly. RESULTS: A one layer closure required less operative time, 16 versus 20.8 minutes (p<0.01), less hemoglobin change, 0.44 versus 1.3 (p<0.01) and less suture materials (p<0.01). But postoperative follow up sonohysteroperitoneography, a one layer closure shows slightly thinning of isthmic layer of myometrium, two layer closure shows more adhesional band and both are similar other findings. CONCLUSION: A one layer does not significantly affect the clinical course than traditional two layer closure. So we recommended a one layer closure when its use is anatomically feasible.
Animals
;
Female
;
Follow-Up Studies
;
Hemostasis
;
Humans
;
Mice
;
Myometrium
;
Operative Time
;
Sutures
;
Uterus
7.Clinical Performance of the Amplified Mycobacterium tuberculosis Direct Test for the Detection of Mycobacterium tuberculosis in Non-respiratory Specimens.
Sung Ryul KIM ; Jeong Hwan SHIN ; Joseph JEONG ; Seon Ho LEE ; Chul Hun CHANG ; Han Chul SON
Korean Journal of Clinical Pathology 1999;19(3):315-319
BACKGROUND: The Amplified Mycobacterium tuberculosis Direct Test (AMTDT) has been developed for the direct detection of M. tuberculosis complex in respiratory specimens. Traditional methods for diagnosis of extrapulmonary tuberculosis such as the acid-fast bacilli (AFB) stain have their well-known limitations. We investigated the usefulness of the AMTDT for a wide range of non-respiratory specimens to establish early diagnosis of extrapulmonary tuberculosis. METHODS: 346 specimens (219 urine, 117 pleural fluid, 6 ascitic fluid, 2 lymph node, 1 gastric aspirate, and 1 pus specimens) from 340 patients referred from November 1997 to September 1998 were tested by the AMTDT. The AMTDT results were evaluated by comparing with clinical diagnosis and smear results. RESULTS: The overall sensitivity, specificity, and positive and negative predictive values of the AMTDT were 82.9%, 93.8%, 64.2%, and 97.6%, respectively. There were no difference in sensitivity and specificity between pleural fluid and urine specimens. In 31 specimens from tuberculosis patients concurrently tested with AMTDT and stain, 15 were only AMTDT positive and 4 were only stain positive. Among the results considered to be false positive, 47.2% of cases were shown as being less than 150,000 relative light units (RLU). In 30 specimens from tuberculosis patients during or after treatment, all six of the patients with reactivation or aggravation were AMTDT positive, and one case was considered to be false positive. CONCLUSIONS: Our study demonstrates the efficacy of the AMTDT in diagnosing extrapulmonary tuberculosis. Prudent interpretation of the AMTDT's results is recommended in case of that being less than 150,000 RLU.
Ascitic Fluid
;
Diagnosis
;
Early Diagnosis
;
Humans
;
Lymph Nodes
;
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Polymerase Chain Reaction
;
Sensitivity and Specificity
;
Suppuration
;
Tuberculosis
8.Clinical Significance of Basic Fibroblast Growth Factor Expression in Bladder Cancer.
Bo Sang NO ; Soon Chul MYOUNG ; Young Seon KIM
Korean Journal of Urology 1997;38(3):263-269
Basic fibroblast growth factor (bFGF) is a potent mitogen and angiogenic protein that may function as an autocrine growth regulator in a variety of malignancies. However, the prognostic value of bFGF expression in bladder cancer has not been adequately studied. We examined tumor tissues of 22 superficial and 25 invasive bladder cancers to define the prognostic value of bFGF expression. We performed immunohistochemical staining of bFGF in formalin-fixed and paraffin-embedded bladder tissue sections using rabbit polyclonal antibody. Microvessels were identified by immunohistochemistry using antibodies to endothelial marker, factor VIII-related antigen. The staining of bFGF were significantly correlated with grade and T stage (p<0.05). The elevated expression of bFGF in patients with invasive bladder cancer was significant correlated with recurrence and 2 year survival (p<0.05). However, no significantly correlation was observed between level of bFGF and vascular counts in frozen sections derived from bladder cancers. These results suggest that the bFGF expression has an important prognostic value in patients with bladder cancer. Immunohistochemical study for bFGF may become a valuable method to predict long-term survival and necessity for adjuvant therapy in patients with bladder cancer.
Antibodies
;
Fibroblast Growth Factor 2*
;
Frozen Sections
;
Humans
;
Immunohistochemistry
;
Microvessels
;
Recurrence
;
Urinary Bladder Neoplasms*
;
Urinary Bladder*
;
von Willebrand Factor
9.The Clinical Significance of Absence of Umbilical Artery End-Diastolic Flow in Severe Pre-Eclampsia and Eclampsia.
Kook LEE ; Yong Seon CHO ; Lee Suk PARK ; Chul Wan JUNG ; Kyung SEO ; Jae Wook KIM
Korean Journal of Obstetrics and Gynecology 1999;42(8):1796-1801
To determine the perinatal mortality and morbidity of fetuses with absent end-diastolic velocities (AEDV) of the umbilical artery in severe pre-eclampsia and eclampsia, the outcome of 5 fetuses with AEDV was compared with that of 35 fetuses with positive end-diastolic velocities (PEDV). The study population comprised 38 cases of severe pre-eclampsia and 2 cases of eclampsia with structurally normal singletons, who had had umbilical artery Doppler velocimetry weekly from admission to delivery. The Doppler velocimetry result was not used for the clinical management. Perinatal death and neonatal morbidity from both groups were further examined in gestational age category to control the influence of preterm births. The incidence of AEDV of the umbilical artery Doppler velocimetry in severe pre-eclampsia and eclampsia was 12.5% (5/40). The AEDV group had a significantly higher incidence than the PEDV group in terms of ceasarean section due to fetal distress (60% : 17%), Apgar score < 7 at 5 minutes (60% : 14%), perinatal death (25% : 0%) and assisted mechanical ventilation (67% : 9%) both at 32-36 weeks. Time intervals from the detection of AEDV to delivery of live neonates varied from the day to 15 days. In conclusion, AEDV in the umbilical artery might be of clinical value in routine surveillance of pregnancies complicated by severe pre-eclampsia and eclampsia, and predict hypoxic fetal condition which needs operative interventions before or during labor and mechanical ventilation after birth.
Apgar Score
;
Cesarean Section
;
Dystocia
;
Eclampsia*
;
Female
;
Fetal Distress
;
Fetus
;
Gestational Age
;
Humans
;
Incidence
;
Infant, Newborn
;
Maternal Death
;
Mortality
;
Parturition
;
Parturition*
;
Perinatal Mortality
;
Pre-Eclampsia*
;
Pregnancy
;
Premature Birth
;
Respiration, Artificial
;
Rheology
;
Trial of Labor
;
Umbilical Arteries*
;
Uterine Rupture
10.Analysis of Chromosomal DNA of Shingella Isolates Using Pulsed-Field Gel Electrophorrsis.
Hyun Ju JUNG ; Seon Ju KIM ; Kook Young MAENG ; Chul Hun CHANG
Korean Journal of Clinical Microbiology 2000;3(1):23-29
BACKGROUND: It is difficult to control an outbreak of Shigella infection, because of the ease of transmission and the resistance to multiple antibiotics. Recently, there were outbreaks of Shigella infection in Chinju area. The objective of this study was to investigate the molecular epidemiology of the outbreaks using pulsed-field gel electrophoresis(PFGE). METHOD: Thirteen S. flexneri strains, 25 S. sonnei strains from Chinju and 15 S. sonnei strains from Pusan were studied. All strains were isolated from stool cultures of diarrheal patients. Identification and antimicrobial susceptibility test those were tested by Vitek GNI and GNS-LH. Chromosomal DNA restricted with Xbal was resolved by PFGE. RESULT: All the S. flexneri strains and 23(92%)S. sonnei strains from Chinju were resistant to one or more antimicrobial agents. All the clinical isolates of S. flexneri showed the same PFGE pattern which was different from type strains(KTCC 2517). PFGE patterns of 25 (100%) S. sonnei strains from Chinju and 12 (80%) S. sonnei strains from Pusan were identical to those of type strain (KTCC 2009). Three S. sonnei strains from Pusan showed distinct PFGE patterns, respectively. CONCLUSION: PFGF demonstrated identical restriction pattern among most of Shigella isolates from Chinju and Pusan, indicating that an outbreak with genetically related strains had occurred. PFGE was useful in molecular epidemiology of Shigella outbreaks
Anti-Bacterial Agents
;
Anti-Infective Agents
;
Busan
;
Disease Outbreaks
;
DNA*
;
Gyeongsangnam-do
;
Humans
;
Molecular Epidemiology
;
Shigella