No abstract available.
Fibroma, Ossifying

No abstract available.
Lung*

No abstract available.

No abstract available.
Korea*

No abstract available.
Pathology*

Obstructive sleep apnea syndrome is associated with significant cardiovascular morbidity and increased mortality. However, it was controversial whether obstructive sleep apnea syndrome could cause pulmonary hypertension. The controversy was resolved by several studies that have shown pulmonary hypertension in 20% to 40% of patients with obstructive sleep apnea syndrome without underlying other cardiopulmonary diseases and reductions in pulmonary arterial pressure in patients with obstructive sleep apnea syndrome after treatment with nocturnal continuous positive airway pressure. Recent studies provide strong evidence for endothelial dysfunction in obstructive sleep apnea syndrome and pulmonary hypertension. Endothelin-1 is a 21 amino acid peptide with diverse biologic activity such as highly potent vasoconstrictor and mitogen regulator that may play a key role in obstructive sleep apnea syndrome and pulmonary hypertension. Continuous positive airway pressure therapy is moderately effective in reducing pulmonary arterial pressure. Further researches are needed to assess the therapeutic efficacy of pharmacologic therapy with agents that inhibit the action of endothelin-1 in obstructive sleep apnea syndrome patients with pulmonary hypertension.
Arterial Pressure ; Continuous Positive Airway Pressure ; Endothelin-1 ; Humans ; Hypertension ; Hypertension, Pulmonary ; Sleep Apnea, Obstructive

No abstract available.

This article has been found to be a duplicate publication.

No abstract available.

No abstract available.
General Practitioners* ; Humans