Animals ; Burns ; complications ; Cicatrix ; etiology ; physiopathology ; Fetus ; physiopathology ; Humans ; Wound Healing

Objective To explore the clinical application value of rapid detection method for respiratory tract influenza virus and mycoplasma pneumonia(MP).Methods 386 cases were selected from patients with respiratory infections in our hospital from Janu-ary 2011 to December 2015 in the study,nasopharyngeal secretions A,B influenza virus were detected by gold immunchromato-graphic assay,the Mycoplasma pneumoniae(MP)was detected by rapid culture,and pathogens-IgM were detected by immunofluo-rescence assay.In the end,the two rapid detection detection method were compared with immunofluorescence assay.Results 386 cases of respiratory tract infections patients were detected by immunofluorescence assay,54 cases were found influenza A virus in-fection,the positive rate was 13.59%,37 cases were found influenza B virus infection,the positive rate was 9.59%,61 cases were found MP infection,the positive rate was 15.80%.In detections of influenza A virus infection and influenza B virus infection,im-munchromatographic assay sensitivity were 20.37%,18.92% and specificity were 93.41%,92.77%.In detection of MP infection, rapid culture sensitivity was 37.70% and specificity was 89.85%.Conclusion Rapid detection of respiratory influenza virus,MP infection sensitivity is low,only as a supplementary means of indirect immunofluorescence assay clinically.

Objective To investigate the method of the operation of the tube type,improve the drying efficiency,and control the occurrence of infection in hospital,reduce the energy consumption.Methods Devices with full automatic washing machine washing out the lumen of 600 pieces were divided into control group and two experimental group by random digital table method each group was 200 pieces,respectively,and using dumped water before drying,luminal devices placed in different position and different container among the three groups in 90 ℃ drying 30 minutes after lumen devices to compare the drying effect.Results At the dry temperature 90℃,the same drying time of 30 minutes,the rate of drying qualified of the experimental group 2 was 100.0％ (200/200),which was higher than 82.5％ (165/200) of the experimental group 1,the difference was statistically significant (x2=38.356,P ＜ 0.05);and also higher than 21％ (42/200) of the control group,the difference was statistically significant (x2=261.157,P ＜ 0.05).Conclusions The new drying operation method can improve the drying efficiency of the tube type,and control the risk of inffection in the hospital.

AIM: To study the effect of streptozotoxin-induced diabetes on cAMP-mediated dilation of rat small coronary arteries (RSCA). METHODS: The diabetes models were induced by injection of streptozotoxin (STZ) to tail vein. The dilation of RSCA was examined by videomicroscopy measurement. RESULTS: (1) STZ diabetes reduced dilation induced by isoproterenol (ISO), operating through cAMP mechanism, in RSCA. This response was in a dose-dependent manner and endothelium-independent relation. (2) STZ diabetes reduced response of RSCA to adenylyl cyclase agonist forskolin and to adenylyl cyclase inhibitor SQ 22536. (3) The 4-aminopyridine, a Kv channel blocker of vascular smooth muscle, suppressed the dilation induced by ISO and forskolin in RSCA of STZ diabetes. (4) The NaF, a G-protein stimulator, reduced the response in RSCA of STZ diabetes. CONCLUSIONS: Although it is known that diabetes impairs endothelium-dependent vasodilation, the effect of diabetes on dilation mechanism independent of endothelium is not well understood. In the present study, it is demonstrated that dilation is reduced in STZ rat small coronary arteries via cAMP signal mechanism and Kv channel of vascular smooth muscle. The G-protein is able to influence this dilation mechanism.

Objective To observe the efficacy and safety of BiPAP ventilator combined with nikethamide for the chronic obstructive pulmonary disease (COPD)complicated with type II respiratory failure.Methods 76 COPD patients complicated with type II respiratory failure were selected as the research subjects,they were randomly divided into two groups by single blind and randomized method,38 cases in each group.The control group was treated with nikethamide therapy,while the observation group used BiPAP combined with mechanical ventilation therapy.The clinical therapeutic effect and adverse reactions were analyzed and compared in the two groups.Results The total effective rate in the observation group was 92.11%,which was significantly higher than 68.42% in the control group (χ2 =10.54,P <0.05).After treatment,the HR and RR of the observation group were (94.28 ±7.62)/min, (13.27 ±4.41)/min,which were significantly decreased than before treatment (t =8.02,8.04,all P <0.05),and which were significantly lower than those in the control group (t =7.54,6.88,P <0.05).After treatment,the pH (7.39 ±0.06),PaO2 (96.31 ±5.44)mmHg,SaO2 (98.42 ±6.87)% in the observation group were significantly increased (t =7.56,7.76,7.45,all P <0.05),PaCO2 (57.36 ±4.98)mmHg was significantly decreased (t =7.54, P <0.05),which had significant differences with the control group (t =6.56,7.02,6.73,7.32,all P <0.05).There was no significant difference in the incidence of adverse reactions between the two groups (χ2 =2.14,P >0.05). Conclusion BiPAP ventilator combined with nikethamide meters has remarkable curative effect and high safety in treatment of COPD patients complicated with type II respiratory failure,which is worthy of clinical reference and popularization.

This systematic review focuses on the management of two types of osseous defects, i.e. dehiscence and fenestration that arise during the placement of dental implant in the edentulous area (delayed implant placement). A systematic online search of main database from 1975 to 2009 was made. Five randomised controlled trials have been identified based on the inclusion criteria. Different management procedures were identified, in which guided bone regeneration procedure was most commonly advocated. Resorbable and non-resorbable m'embranes were compared, in which resorbable membrane was preferred as it caused less complicatiQn of membrane exposure or risk of infection. The benefit of using bone substitute along with membrane in rypairing bony defects cannot be concluded.

Based on a review of the practices of echinococcosis control in China and of the historical experience from the international community in the field,this paper discussed the research achievements and challenges.The author indicated that it is a realistic time to launch a comprehensive control program in western China and there are urgent needs for scientific research integrating into the program.

Objective To assess perioperative nursing potential effects on dissection aortic aneurysm cases receiving blood vessel prosthesis. Methods In order to prevent the aortic aneurysm rupture, pain degree and mental condition were evaluated in 28 patients with dissection aortic aneurysm before therapy. Blood pressure was also controlled in proper level. All were received blood vessel prosthesis. Postopertive care were performed for every organism system, controlling blood pressure and preventing complication. Results After perioperative nursing for (3.3?2.2) days, 27 cases were recoveried from illness while 1 case died from MODF.Conclusions Perioperative nursing play an important role in blood vessel prosthesis.

Thyroid associated ophthalmopathy (TAO) is an organ-specific autoimmune-inflammatory disorder,ranking top among the orbital diseases with highest incidences.TAO is characterized by a complex pathogenesis,including glycosaminoglycan and hyaluronic acid deposition,fibrosis of extraocular muscle and adipose degeneration of ocular tissue.The physical manifestations of the disease include periorbital edema,double vision,ophthalmoptosis,ocular dryness,eyelid retraction and on occasion vision loss secondary to optic nerve compression.Selenium evolves in the diversified pathogenesis of TAO.Although the therapeutic effects for TAO of selenium have already been proven,some problems appear to be no clear among the clinicians,such as its optimum dose,duration of the treatment,and safety to date,etc.Nowadays,the mechanism of selenium supplementation in TAO treatment includes neutralization of reactive oxygen,inhibition of HLA-DR expression,inhibition of secretion of TSHR-Ab and TPO-Ab.The aim of the review was to summarize the studies of selenium supplementation theray for TAO.