No abstract available.
Brain Death* ; Brain*

Inflammatory nodular vascular diseases of the legs have been classified as severah distinctive entities based on their minor clinical and pathological variations. They have so many common features which often make the differential diagnosis difficult or impossihIe that reevaluation of these diseases is one of the important problems in the dermatologic field. The author studied the clinical and pathological relationship of those diseases in 86 patients including 70 cases of erythema nodosum, 7 of erythema induratum, 3 of panniculitis, and 6 of nodular vasculitis. The results are as follows; l. Erythema nodosum, erythema induratum and nodular vasculitis are most common. In the spring and patient are most often in their twenties. 2. Common to all, females are more commonly affected than males. 3.Erythema nodosum, erythema induratum and nodular vasculitis reveal no definite difference in their clinical pictures and laboratory findings. 4. Erythema nodosum, erythema induratum and nodular vasculitis are founded to be assoeiated with mostly streptococcal infection and/or tuberculosis; panniculitis is associated mainly with streptococcal infection.5. In histopathological findings, tubercle formation and caseation necrosis are more marked in erythema induratum than in erythema nodosum and nodular vasculitis. 6. The panniculitis is characterized by inflammation of the small sized vessels in. subcutaneous tissues; Nodular vasculitis reveals its main lesion in the large sized. Vessels of lower dermis. In erythema nodosum and erythema induratum, small. And medium-sized vessels are involved in subcutaneous tissue.
Dermis ; Diagnosis, Differential ; Erythema Induratum ; Erythema Nodosum ; Female ; Humans ; Inflammation ; Leg* ; Male ; Necrosis ; Panniculitis ; Streptococcal Infections ; Subcutaneous Tissue ; Tuberculosis ; Vascular Diseases ; Vasculitis

No abstract available.
Korea*

No abstract available.
Schools, Medical*

Ehlers-Danlos syndrome, a heritable disorder of connective tissue by autosomal dominant mode, is very rare disease in this country. Authors described a typical case in 39 years old woman who had a daughter of 6 years old also affectect by this disorder. The patient had the characteristic hyperelasticity of the skin and hyperextensibility of the jonts especially at metacarpophalangeal joint of the hands. She also revealed hyperterolism and aortic insufficiency on X-ray and E.C.G. examination.
Adult ; Child ; Connective Tissue ; Ehlers-Danlos Syndrome ; Family Characteristics* ; Female ; Hand ; Humans ; Metacarpophalangeal Joint ; Nuclear Family ; Rare Diseases ; Skin

A clinical and histological study of typical sebaceous epithelioma (basal cell epitheioma with sebaceous differentiation) developed secondarily in lesions of nevus sebaceus of Jadassohn is presented. The patient was 42 years old male. The sebaceous epithelioma tends to have about the same clinical characteristics as undifferentiated basal cell epithelioma but it is more often a yellow color. Sebaceous epitheliova may arise from nevus sebaceus and it is preursor of undifferentiated basal ce]1 epithelioma. Histological]y, the preparation showed massive development of sebaceous gland, papillomatous epidermal hyperplasia and maturation of apocrine glands. The tumor cell nests were mostly composed of large sheets of irregularly shaped cells in palisading pattern at the periphery. There were Iarge number of cells with vacuolated cytoplasm resembling sebaceous cell in certain part of the tumor cell masses and several keratin pearls. Diagnosis confirmed by clinical appearance and histological picture. These lesions could be treated sucessfully by wide excision.
Adult ; Apocrine Glands ; Carcinoma* ; Carcinoma, Basal Cell ; Cytoplasm ; Diagnosis ; Humans ; Hyperplasia ; Male ; Nevus* ; Nevus, Sebaceous of Jadassohn* ; Sebaceous Glands

No abstract available.
Cartilage* ; Enophthalmos* ; Ribs* ; Transplants*

No abstract available.
Brain Death* ; Brain*

The predictive accuracy of the SRK II, SRK/T and Holladay formulas was evaluated in 22 eyes with sever myopia who had phacoemulsification and implantaton of posterior chamber IOL without suture. These patients were followed up for at least 6 months postoperatively. Correlation coefficient between the predicted refraction and actual refraction was 0.57(P<0.01) in the eyes using the SRK/T, 0.566(P<0.01) in the Holladay and (0.06(P=0.791) in the SRK II. The mean absolute error in the SRK/T 0.85 was smaller than that of the Holladay 1.04 and the SRK II1.08(p<0.05). The percentage of the eyes with absolute error within 1D was 68% in the SRK/T, 68% in the Holladay and 53% in the SRK II, but there was no statistically significant difference between them(p>0.05). The percentage of the eye with hyperopic shift(more hyperopic actual refraction than the predicted refraction) was 77% in the SRK II, 77% in the SRK/T and 86% in the Holladay, but there was no statistically significant difference between each formula(p>0.05). In conclusion, the SRK/T has the better predictive accuracy than the SRK II and Holladay in severe myopia and hyperopic shift tends to occur with the application of all three formulas.
Humans ; Lenses, Intraocular* ; Myopia ; Phacoemulsification ; Sutures

BACKGROUND: Although hypoxic pulmonary vasoconstriction (HPC) and hypoxic coronary vasodilatation (HCD) have been recognized by many researchers, the precise mechanism remains unknown. As isolated arteries will constrict or relax in vitro in response to hypoxia, the oxygen sensor/transduction mechanism must reside in the arterial smooth muscle, the endothelium, or both. Unfortunately, much of the current evidence is conflicting, especially concerning to the dependency of HPC and HCD on the endothelium and the role of the K+ channel. Therefore, this experiment was attempted to clarify the dependency of HPC and HCD on the endothelium and the role of the K+ channel on HPC and HCD. METHODS: HPC was investigated in isolated main pulmonary arteries precontracted with norepinephrine (NE). HCD was investigated in isolated left circumflex coronary artery precontracted with prostaglandin F2 alpha. Vascular rings were suspended for isometric tension recording in an organ chamber filled with Krebs-Henseleit solution. Hypoxia was induced by gassing the chamber with 95% N2 +5% CO2, which was maintained for 15 - 25 min. RESULTS: 1)Hypoxia elicited a vasoconstriction in NE-precontracted pulmonary arteries with endothelium, but a vasodilatation in PGF 2 alpha-precontracted coronary arteries with and without endothelium. There was no difference between the amplitude of the HPC and HCD induced by two consecutive hypoxic challenges and the effect of normoxic and hyperoxic control Krebs-Henseleit solution on subsequent response to hypoxia. 2)Inhibition of NO synthesis by the treatment with Nw-nitro-L-arginine reduced HPC in pulmonary arteries, but inhibition of the cyclooxygenase pathway by treatment with indomethacin had no effect on HPC and HCD, respectively. 3)Blockades of the TEA-sensitive K+ channel abolished HPC and HCD. 4)Apamin, a small conductance Ca2+/-activated K+ (KCa) channel blocker, and iberiotoxin, a large conductance KCa channel blocker, had no effect on the HCD. 5)Glibenclamide, an ATP-sensitive K+ (KATP) channel blocker, reduced HCD. 6)Cromakalim, an K(ATP) channel opener, relaxed the coronary artery precontracted with prostaglandin F2 alpha. The degree of relaxation by cromakalim was similar to that by hypoxia and glibenclamide reduced both hypoxia- and cromakalim-induced vasodilations. 7)Verapamil, a Ca2+ entry blocker, caffeine, a Ca2+ emptying drug; and ryanodine, an inhibitor of Ca2+ release from SR, reduced HPC, respectively. CONCLUSION: HPC is dependent on the endothelium and is considered to be induced by inhibition of the mechanisms of NO-dependent vasodilation while HCD is independent of the endothelium and is considered to be induced by activation of the K(ATP) channel.
Anoxia ; Arteries ; Caffeine ; Coronary Vessels ; Cromakalim ; Dinoprost ; Endothelium ; Glyburide ; Indomethacin ; Muscle, Smooth ; Norepinephrine ; Oxygen ; Prostaglandin-Endoperoxide Synthases ; Prostaglandins F ; Pulmonary Artery ; Relaxation ; Ryanodine ; Vasoconstriction* ; Vasodilation*