Using a paradigm similar to the one employed by Crowe et al., this study was undertaken to determine the genetic characteristics of multiple neurofibromatosis in Korean people. Thirty three subjects were used in this study. All subjects were identified through an exarnination of the records of all patients who had visited the Department of Dermatology of Chonnam Medical University Hospital between 1967 and 1976. Relatives of subjects were examined whenever possible, The results of the study projected that the total number of persons in Chonriarn Province afflicted with multiple neurofibromatosis lies sornewhere between 880 and 16,500. Crowe estimated that between 2500 and 3300 patients could be found on Michigans lower peninsula. Sixty percent of this studys subjects presented as sporadic patients, a condition thought to be the resu.lt of a genetic mutation. They had no blood relatives who demonstrated the disease. Fifty percent of Crowes subject were found to be sporadic patients, and a similar study by a Japanese investigator revealed a sporadic patient rate of sixty percent. In this study, the rernaininp 40% of the subject group conformed to the expected genetic frequency, thus pointing toward the fact that rnultiple neurofibrornatosis is a highly penetrant autosomal dorninant disease. This was demonstrted by the fact that, of the 79 offspring bad by this group, 82 persons demonstrated multiple neurofibromatosis. This study also suggested somatic mutation in 3 of the 20 sporadic patients. Because this nutation did not occur at the germinal level, the patient is much less likely to transmit this disease to his offspring, One patient showed the usual clinical and family traits but the chromosome analysis was negative. Genetic issues associated with multiple neurofibromatosis are also discussed in this sturly.
Asian Continental Ancestry Group ; Crows ; Dermatology ; Humans ; Jeollanam-do ; Michigan ; Neurofibromatoses* ; Research Personnel

This article describes the activity of the "Medical termonology practical committee (MTPC) of Korean Medical Association (KMA). In 2001, MTPC of KMA published the 4th edition of "English-Korean, Korean-English Medical terminology" which contains about 5,000 medical terms. The MTPC will continue reviewing the vocabularies. Obsolete terms will be discarded, new terms will be added, and the remainder will be revised by through-going revision of vocabulary. Our aim is to reflect the current usage of medical terms in the form of easily understandable Korean terms.
Vocabulary

No abstract available.
Urology*

No abstract available.
Occupational Exposure* ; Trichloroethylene*

Fragile fractures, also known as osteoporosis fractures, insufficiency fractures, and senile fractures are a significant problem encountered by orthopedic surgeons. Calcium and vitamin D are essential for maintaining bone health and deficiencies in calcium and vitamin D are major risk factors for the development of osteoporosis. Sufficient amounts of calcium are also required for fracture-callus mineralization. Hence, compromised bone repair that is frequently observed in osteoporotic patients might be attributed to calcium and vitamin D deficiencies. Consequently, calcium and vitamin D supplementation represents a potential strategy for treating compromised fracture healing in osteoporotic patients.There is some clinical evidence of the positive effect of supplementation in fracture healing and posttraumatic bone turnover, but research in this area is ongoing. Calcium and vitamin D should be the primary treatment of choice in osteopenic patients with an insufficiency of calcium and vitamin D and for the prevention of secondary osteoporotic fractures. Calcium and vitamin D can also be used as addition to other primary osteoporotic medications such as antiresorptive or bone-forming agents. The role of calcium and vitamin D in fracture healing and the therapeutic potential of calcium and vitamin D supplementation is summarized in this context.

Fragile fractures, also known as osteoporosis fractures, insufficiency fractures, and senile fractures are a significant problem encountered by orthopedic surgeons. Calcium and vitamin D are essential for maintaining bone health and deficiencies in calcium and vitamin D are major risk factors for the development of osteoporosis. Sufficient amounts of calcium are also required for fracture-callus mineralization. Hence, compromised bone repair that is frequently observed in osteoporotic patients might be attributed to calcium and vitamin D deficiencies. Consequently, calcium and vitamin D supplementation represents a potential strategy for treating compromised fracture healing in osteoporotic patients.There is some clinical evidence of the positive effect of supplementation in fracture healing and posttraumatic bone turnover, but research in this area is ongoing. Calcium and vitamin D should be the primary treatment of choice in osteopenic patients with an insufficiency of calcium and vitamin D and for the prevention of secondary osteoporotic fractures. Calcium and vitamin D can also be used as addition to other primary osteoporotic medications such as antiresorptive or bone-forming agents. The role of calcium and vitamin D in fracture healing and the therapeutic potential of calcium and vitamin D supplementation is summarized in this context.

No abstract available.
Adrenocorticotropic Hormone* ; Infant ; Infant, Newborn ; Spasms, Infantile*

No abstract available.
Counseling* ; Infertility*

A treatment should be functional, esthetic, conservative and periodontally healthy in order to meet criteria of an ideal dental procedure. in a prsthodontic patient with horizontal and/or vertical space deficiency, orthodontic tooth movement should be considered as a pre-prosthetic procedure. With a conventional technique, orthodontic treatment is a time-consuming and uncomfortable procedure. Pre-prosthetic orthodontic treatment, however, is no longer difficult procedure with the help of recently developed techniques, such as passive bracketing. The present article outlines the problems and causes of horizontal and vertical space deficiency in prosthodontic patients, and presents efficient pre-prosthetic orthodontic treatment modalities with typical clinical cases.
Humans ; Prosthodontics* ; Tooth Movement

No abstract available.
Education* ; Forensic Medicine* ; Korea*