Across - Sectional study was carried out to assess of occupational diseases in Thai Nguyen metalurgical industry. The study was conducted to workers which had been exposed more than 5 years old with risk factors. The results showed that: Among 1267 workers were medically examined, the prevalence of silicosis was high: Iron and steel workers: 9.7%, Non - ferrous metalurgical workers: 10.4%. The rate of sillicosis had close relationship with years of exposure and working enviroment. In non - ferrous metalurgical industry, the rate of poisoning was high. The serious status of diseases was about 20% with lead poisoning. Many patients were died because of Asenic and Benzen poisoning.
Occupational Diseases ; Epidemiology ; Risk factors

Study of respiratory function of 120 males’ workers ages of 25-45 years in some cement and asbestos factories was performed to give the methods for reducing respiratory diseases. Results showed that: the working time of these workers was over 5 years. Their respiratory function reduced by aged and working time. The more working time was, the more exposed time to dust in working environmental was. The results indicated that it is necessary to give reducing methods of silidust in producing process, to improve work condition, and to reduce diseases of respiratory
Respiratory Tract Diseases ; Occupational Diseases

The cross-sectional study with interviews people who exposed to chemicals for plant protection at 528 households in vegetable areas in Thai Nguyen city showed that: the rate of people directly exposing to pesticides in study group is very high (34.8%). 55.3% of people exposing to pesticides are women, 20% out of them under 18 and over 60 years old. Knowledge and practice on safety in using pesticides are even low. Common manifestations: tiredness, headache, dizziness, numbness account for 3.1-48.1%. The rate of nerve and dermal diseases is relatively high
Agrochemicals ; Vegetables

The microclimate at working environment is bad, especially radiation. The particle levels at most workshops are higher than approved standard. The morbidity is increasing between 1999 to 2000. The increase in morbidity with professional age was noted. The incidence of skin, dental and ORL diseases increase significantly. The alergic cutaneous diseases affect to fourth of workers. 11.48% of examined persons have silicosis.
Occupational Diseases ; Microclimate

We studied on hematological parameters, lymphocytes distribution and stem cell (CD34 positive) count from cord blood of 43 healthy newborn at obstetrics department, Bach Mai hospital. The result showed that, stem cell count of cord blood is high (16.2% of nucleated cell, equal to 2.4+/- 0.3 G/l). this will be useful to allegoric stem cell transplantation. However, relatively high count of white cell (especially T lymphocyte) can be considerable to procedure and transplant result, free of graft versus host disease.
Fetal Blood ; Bone Marrow Transplantation

No abstract available.
Memory

No Abstract Available.
Humans ; Physicians, Primary Care* ; Primary Health Care*

Abnormalities of the short arm of chromosome 12 are relatively common in childhood ALL. Approximately 5~7% of children with ALL have cytogenetic evidence of a translocation involving 12p, whereas 3~5% have deletions which suggest the presence of a tumor suppressor gene at this location. Through the use of sensitive molecular techniques, 12p or 12p 12~13 loss of heterozygosity (LOH) has been demonstrated in approximately 25 oyo of childhood ALL cases. FISH mapping has detected a minimum region of overlap for the 12p deletions between the TEL(ETV6) and CDKN1B(KIP1) geness). Recently, chromosomal translocations involving the TEL gene at 12p13 have been cloned in several hematopoietic disorders. In ALL cells with thet(12;21)(p13;q22), the 5' part of TEL is fused with the AML1 gene. Abnormalities of 12p, especially the t(12 ; 21), are more reliably detected by FISH than by classical cytogenetics because the translocated portions 12p and 21q are virtually identical cytologically. When FISH was combined with Southern blotting and RT-PCR, the t(12;21) was identified as a recur-ring chromosomal abnormality in 16~25% of childhood B-lineage ALL. Despite the identification of the fusion partners in the t(12;21), the actual function of the TEL-AML1 and AML1-TEL fusion proteins in promoting malignant transformation is unclear. Whether the TEL-AML1 fusion alone is necessary and sufficient for malignant transformation in ALL and whether TEL inactivation has a role in leukemogenesis is currently unknown. Loss of the CDKN2(p16) gene at 9p21 is a common genetic abnormality in ALL and a variety of other malignancies. Homozygous CDKN2 deketions have been deteced in approximate 15% of B-lineage ALL and 75% of T-lineage ALL cases. The p16 protein functions as an inhibitor of cyclin-dependent kinase 4, and normally acts to stop cell cycle progression. Whether loss of p16 alone is necessary and sufficient for malignant transformation in childhood ALL has not been determined.
Arm ; Blotting, Southern ; Cell Cycle ; Child ; Chromosome Aberrations ; Chromosomes, Human, Pair 12 ; Clone Cells ; Cyclin-Dependent Kinase 4 ; Cytogenetics ; Genes, Tumor Suppressor ; Humans ; Loss of Heterozygosity ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; Translocation, Genetic

We must define resources to inform a developmental tasks. Implement industrious and thrifty, against peculation, spendthrift. Affirmation on main force to bring into play the internal force and impulse development. Building and informing on the democratic institution. Rearranging the governmental enterprises; people health care, health care for poor
Public Health ; Delivery of Health Care

From 2 years of program for diagnostic and treatment quality elevation to 4 main diseases of blood and hematopoiesis, consisting of acute leukemia (AL), idiopathic thrombocytopenic purpura (ITP), aplastic anemia (AA) and hemophilia, we get some results. Firstly, we designed the basic feature of subtypes of AL, found out new subtypes, such as stem cell AL. which could not be detected by conventional techniques. Basing upon development of new techniques of bone marrow biopsy and immunological technique, we can diagnose exactly some difficult cases of hematopoiesis, such as aplastic anemia, myelodisplassia, bone marrow metastasia, multiple myeloma, smouldering AL. This takes an important part to elevate treatment quality of acute blood diseases in Vietnam. On treatment field, splenectomy can be effective for immunomodulation in patients, who display dis-balance of CD4/CD8 ratio.
Hematologic Diseases ; Genetic Enhancement ; Diagnostic ; Therapeutics ; Hematopoiesis ; Anemia, Aplastic ; Hemophilia A ; Purpura, Thrombocytopenic, Idiopathic ; Leukemia