No abstract available.
Biopsy, Fine-Needle* ; Breast*

A 17 year old girl underwent a surgery of spine fusion for a tuberculous cervical spine (C(4~5) ) under halothane-02 anesthesia. On the 1st postoperative day, sudden high fever(39.7 degrees C) with chillness and leukocytosis with eosinophilia were noted. On the following day, generalized jaundice, right hypochondralgia and slight hepatomegaly with marked impairment of liver function tests were noted. HB antigens were negative and there was no transfusion history of blood or blood products. About 2 months after operation, she was discharged with symptomatic improvement and almost normal laboratory data.
Anesthesia* ; Drug-Induced Liver Injury* ; Eosinophilia ; Female ; Halothane* ; Hepatomegaly ; Humans ; Jaundice ; Leukocytosis ; Liver Function Tests ; Spine

Succinylcholine has been reported to cause elevation of intraocular pressure(IOP.) IOP measurements, following single and mixed intravenous administration of succinylcholine and pancuronium, given immediately after thiopental, were made in 40 surgical patients, to assess the effect of pacuronium on the succinylcholine induced increase in IOP. The major findings of this study were as follows; 1) Tbiopental showed significant lowering effect on IOP. 2) A single intravenous injection of succinylcholine(1mg/kg) caused a slight rise of lOP. 3) A single intravenous injection of pancuronium(4mg) caused a slight decrease of IOP. 4) A mixed intravenous injection of succinylcholine and pancuronium increased the IOP more significantly than succinylcholine alone, This also means that pancuronium do not inhibit succinylcholine induced increase In IOP. 5) Tracheal intubation caused a rise of IOP significantly.
Administration, Intravenous* ; Humans ; Injections, Intravenous ; Intraocular Pressure* ; Intubation ; Pancuronium* ; Succinylcholine* ; Thiopental

No abstract available.
Burns* ; Humans

The early postpartum period is crucial toward in recovery form childbirth and attainment of the maternal role. Maternal role attainment is a complex social and cognitive process of stimulus-response accomplished by learning. Helping for maternal role attainment is one of nursing goals in the early postpartum period. Based on King's conceptual framework for nursing, this study was planned as descriptive correlation study to determine the significant differences of the degree of nursery room nurses' role performance according to several variables of personal, interpersonal, and working system of nurses in nursery room, The purpose of this study was to contribute to the planning of nursing care to help maternal role attainment of the early postpartum period of mothers and to the development of relevant nursing theory, The data were collected from R3b. 3 to 28 by questionnaires with 273 nurses in nursery room. The instruments for this study were consisted of four parts: 21 questions for roll performance of nurse ; 37 questions for personal system of nurse including 31 questions for role perception of nurse ; 65 questions for interpersonal system including 63 questions for job stress of nurse ; 18 questions for working system of nurse. The toes to measure role performance and role perception, and job stress of nurse were tested for internal reliability. Cronbach's Alphas were 0.9612, 0.9058, and 0.9649. The data were analysed by using in S.A.S. computerized program and included percentage, t-test, ANOVA, Pearson Correlation Coefficient, and Duncan multiple range test. The conclusions obtained from this study are summarized as follows : 1. The mean score of the items of role performance was 2.12(SD=0.55) in Likert's 4 points scale. 2. The degree of role performance was significantly different according to role perception(p=0.0001), age(p=0.006), educational background(p=0.002), and certificate of midwife(p=0.03) among variables of personal system of subjects. 3. The degree of role performance was significantly different according to job stress(p=0.0001) and numbers of children(p=0.006) among variables of interpersonal system of subjects. 4. The degree of role performance was significantly different according to having opportunities for baby(p=0.03), the degree of flexibility to bring baby to mother's room(p=0.046), the scope of visitor for baby(p=0.016), the degree of flexibility of visiting for baby(p=0.049), the degree of participation of nurse in establishing visiting rules(p=0.017), existence and/or nonexistence of rules for breast feeding(p=0.010), existence and/or nonexistence of education for breast feeding(p=0.009), existence and/or nonexistence of breast feeding room(p=0.013), concret methods for breast feeding(p=0.003), working place(p=0.0001), and career(p=0.019) among variables of personal system of subjects.
Breast ; Breast Feeding ; Education ; Humans ; Learning ; Mothers* ; Nurseries* ; Nursing ; Nursing Care ; Nursing Theory ; Parturition ; Pliability ; Postpartum Period* ; Statistics as Topic ; Toes ; Child Health ; Surveys and Questionnaires

No abstract available.
Niemann-Pick Disease, Type A*

BACKGROUND: Although post-anesthetic shivering may be a temporary phenomenon, it leads to detrimental effects such as increased oxygen consumption, hypoxemia, and difficulty in monitoring. Doxapram is a relatively new treatment for post-anesthetic shivering, but there have been few reports about its minimum effective dose. The purpose of this study was to find the minimum dose of doxapram which would show an antishivering effect. METHODS: Sixty patients who had developed post-anesthetic shivering were divided into six groups of ten patients each. The groups were divided into a control group, which received normal saline, and the doxapram groups, which received five different doses of doxapram (0.15, 0.2, 0.5, 1.0, 1.5 mg/kg). The antishivering effect (2, 5, 10, 15 minutes after treatment), blood pressure, heart rate and temperature were compared among the groups. RESULTS: There was a significant difference in antishivering effect between the group which received normal saline and the groups which received doxapram; however, there was no significant difference within the groups which received doxapram. CONCLUSIONS: We conclude that the dose of doxapram required to achieve an antishivering effect is much less than that currently in use.
Anoxia ; Blood Pressure ; Doxapram* ; Heart Rate ; Humans ; Oxygen Consumption ; Shivering*

PURPOSE: The well-known prognostic factors for breast cancer, such as axillary lymph node status, do not always account for the exact outcome. The developinent of other accurate prognostic factors would help in assessing high risk for the disease recurrence and death. Recently, there are reports that peritumoral lymphatic vessel invasion is a good prognostic factor to solid tumors in animal studies and clinical trials. This study was performed to estimate the significance of peritumoral lymphatic vessel invasion (PLVI) as a prognostic factor in breast cancer. Also, PLVI was compared with established clinicopathological prognostic factors and hormone receptors. MATERIALS AND METHODS: A group of patient was selected from the Department of Surgery, College of Medicine, Hallym University, which consists of 43 out of 96 patients who received curative operation from 1985 to 1993. Peritumoral lymphatic vessel invasion by tumor cells on H&E stain was considered PLVI positive. We classified 43 breast-cancer patients into 32 with negative PLVI and ll with positive PLVL. We estimated the correlation between the PLVI and other established prognostic factors. We also calculated survivals based on PLVI. RESULTS: The 4-year disease-free survival rate was 61.8+/-8.7%, and the 4-year overall survival rate was 73.0+/-8.0%. The receptor status of estrogen and of progesterone had significant impacts on survival (ER: p=0.0001, PR: p=0.0001). Also, metastasis status of lymph node had significant impacts on overall survival (p=0.0148). We found a significant correlation between PLVI and tumor size (p=0.004), estrogen receptor (p=0.002), progesterone receptor (p=0.006), but could not find any significant corelation between PLVI and menopausal status, histologic grade, nuclear grade, lymph node metastasis. PLVI status was corelated with disease free survival rate (p=0.01) and overall survival rate (p=0.01). CONCLUSION: The determination of PLVI in breast cancer tissue may be useful as a prognostic factor, but it is necessary to investigate the PLVI in a large number of patients before this conclusion can be stated with certainty.
Animals ; Breast Neoplasms* ; Breast* ; Disease-Free Survival ; Estrogens ; Humans ; Lymph Nodes ; Lymphatic Vessels ; Neoplasm Metastasis ; Progesterone ; Receptors, Progesterone ; Recurrence ; Survival Rate

PURPOSE: The purpose of this predictive study was to identify factors affecting health related quality of life (HRQoL) in patients with rheumatoid arthritis (RA). METHODS: The participants in this study were 131 patients with RA who were recruited from the outpatient clinic of a university hospital in Seoul. Disease activity in rheumatoid arthritis was evaluated by calculating the Disease Activity Score 28. Disability in activities of daily living (ADL) was assessed with the Korean Health Assessment Questionnaire, and depression with The Center for Epidemiologic Studies Depression Scale. HRQoL was evaluated using The Short Form 36 Health Survey. Data were analyzed using descriptive statistics, correlation, and hierarchical multiple regression. RESULTS: Pain, disability in ADL, disease activity, and depression correlated negatively with physical and mental dimensions of HRQoL. But hierachical multiple regression analysis revealed that disability in ADL and depression were the only variables negatively influencing physical and mental QoL after adjustment for influences of sociodemographic variables. CONCLUSION: Results of this study suggest that disability in ADL and depression, rather than disease activity and pain have profound effects on HRQoL in patients with RA. Further studies are needed to assess the predictive ability of disease activity and pain on HRQoL in this population.
*Activities of Daily Living ; Adaptation, Psychological ; Adult ; Aged ; Arthritis, Rheumatoid/pathology/*psychology ; *Depression ; Female ; Health Status ; Hospitals, University ; Humans ; Male ; Middle Aged ; Pain ; *Quality of Life ; Questionnaires ; Republic of Korea

The well-known prognostic factors for breast cancer, such as axillary lymph node status, do not always account for the exact outcome. The development of other accurate prognostic factors would help in assessing high risk for the disease recurrence and death. Recently, there are reports that peritumoral lymphatic vessel invasion is a good prognostic factors to solid tumors in animal studies and clinical trials. This study was performed to estimate the significance of peritumoral lymphatic vessel invasion (PLVI) as a prognostic factor in breast cancer. Also, PLVI was compared withb establishwd established clinicopathological prognostic factors and hormone receptors. MATERIALS AND METHODS: A group of patient was selected from the Department of Surgery, College of Medicine, Hallym University, which consists of 43 out of 96 patients who received curative operation from 1985 to 1993. Peritumoral lymphatic vessel invasion by tumor cells on H&E stain was considered PLVI positive. We classified 43 breast-cancer patients into 32 with negative PLVI and 11 with positive PLVI. We estimated the correlation between the PLVI and other established prognostic factors. We also calculated survivals based on PLVI. RESULT: The 4-year disease-free survival rate was 61.8+/-.7%, and the 4-year overall survival rate was 73.0+/-.0%. The receptor status of estrogen and of progesterone had significant impacts on survival (ER: p=0.0001, PR: p=0.0001). Also, metastasis status of lymph node had significant impacts on overall survival (p=0.0148). We found a significant correlation between PLVI and tumor size (p=0.004), estrogen receptor (p=0.002), progesterone receptor(p=0.006), but could not find any significant correlation between PLVI and menopausal status, histologic grade, unclear grade, lymph node metastasis. PLVI status was correlated with disease free survival rate (p=0.01) and overall survival rate(p=0.01). CONCLUSIONS: The determination of PLVI in breast cancer tissue may be useful as a prognostic factor, but it is necessary to investigate the PLVI in a large number of patients before this conclusion can be stated with certainty.
Animals ; Breast Neoplasms* ; Breast* ; Disease-Free Survival ; Estrogens ; Humans ; Lymph Nodes ; Lymphatic Vessels* ; Neoplasm Metastasis ; Progesterone ; Recurrence ; Survival Rate