1.Outcomes of Concomitant Maze Procedure in Tricuspid Repair for Severe Tricuspid Regurgitation
Ilkun PARK ; Suryeun CHUNG ; Yang Hyun CHO ; Kiick SUNG ; Wook Sung KIM ; Kyungsub SONG ; Joong Hyun AHN ; Chang Seok JEON ; Pyo Won PARK ; Dong Seop JEONG
Journal of Korean Medical Science 2024;39(15):e143-
Background:
We aimed to analyze the impact of concomitant Maze procedure on the clinical and rhythm outcomes, and echocardiographic parameters in tricuspid repair for patients with severe tricuspid regurgitation (TR) and persistent atrial fibrillation (AF).
Methods:
Patients who had severe TR and persistent AF and underwent tricuspid valve (TV) repair were included in the study. Both primary TR and secondary TR were included in the current study. The study population was stratified according to Maze procedure. The primary outcome was major adverse cardiovascular and cerebrovascular event (MACCE) at 15 years postsurgery. Propensity-score matching analyses was performed to adjust baseline differences.
Results:
Three hundred seventy-one patients who underwent tricuspid repair for severe TR and persistent AF from 1994 to 2021 were included, and 198 patients (53.4%) underwent concomitant Maze procedure. The maze group showed 10-year sinus rhythm (SR) restoration rate of 55%. In the matched cohort, the maze group showed a lower cumulative incidence of cardiac death (4.6% vs. 14.4%, P = 0.131), readmission for heart failure (8.1% vs. 22.2%, P = 0.073), and MACCE (21.1% vs. 42.1%, P = 0.029) at 15 years compared to the non-maze group. Left atrial (LA) diameter significantly decreased in the maze group at 5 years (53.3 vs. 59.6 mm, P < 0.001) after surgery compared to preoperative level, and there was a significant difference in the change of LA diameter over time between the two groups (P = 0.013).
Conclusion
The Maze procedure during TV repair in patients with severe TR and persistent AF showed acceptable SR rates and lower MACCE rates compared to those without the procedure, while also promoting LA reverse remodeling.
2.Temporary Right Ventricular Assist Device Insertion via Left Thoracotomy after Left Ventricular Assist Device Implantation
Ilkun PARK ; Yang Hyun CHO ; Su Ryeun CHUNG ; Dong Seop JEONG ; Kiick SUNG ; Wook Sung KIM ; Young Tak LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 2019;52(2):105-108
Right heart failure is a relatively common complication after left ventricular assist device (LVAD) implantation. Severe right heart failure can be managed by temporary right ventricular assist device (RVAD) implantation. However, trans-sternal RVAD insertion requires a subsequent third sternotomy for cannula removal. Herein, we present a case of RVAD insertion via a left anterior mini-thoracotomy after LVAD implantation in a patient with alcohol-induced cardiomyopathy.
Cardiomyopathies
;
Catheters
;
Heart Failure
;
Heart-Assist Devices
;
Humans
;
Sternotomy
;
Thoracotomy
3.Primary Chest Wall Sarcoma: Surgical Outcomes and Prognostic Factors
Ilkun PARK ; Sumin SHIN ; Hong Kwan KIM ; Yong Soo CHOI ; Jhingook KIM ; Jae Ill ZO ; Young Mog SHIM ; Jong Ho CHO
The Korean Journal of Thoracic and Cardiovascular Surgery 2019;52(5):360-367
BACKGROUND: Primary chest wall sarcoma is a rare disease with limited reports of surgical resection. METHODS: This retrospective review included 41 patients with primary chest wall sarcoma who underwent chest wall resection and reconstruction from 2001 to 2015. The clinical, histologic, and surgical variables were collected and analyzed by univariate and multivariate Cox regression analyses for overall survival (OS) and recurrence-free survival (RFS). RESULTS: The OS rates at 5 and 10 years were 73% and 61%, respectively. The RFS rate at 10 years was 57.1%. Multivariate Cox regression analysis revealed old age (hazard ratio [HR], 5.16; 95% confidence interval [CI], 1.71–15.48) as a significant risk factor for death. A surgical resection margin distance of less than 1.5 cm (HR, 15.759; 95% CI, 1.78–139.46) and histologic grade III (HR, 28.36; 95% CI, 2.76–290.87) were independent risk factors for recurrence. CONCLUSION: Long-term OS and RFS after the surgical resection of primary chest wall sarcoma were clinically acceptable.
Humans
;
Rare Diseases
;
Recurrence
;
Retrospective Studies
;
Risk Factors
;
Sarcoma
;
Thoracic Wall
;
Thorax
4.Temporary Right Ventricular Assist Device Insertion via Left Thoracotomy after Left Ventricular Assist Device Implantation
Ilkun PARK ; Yang Hyun CHO ; Su Ryeun CHUNG ; Dong Seop JEONG ; Kiick SUNG ; Wook Sung KIM ; Young Tak LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 2019;52(2):105-108
Right heart failure is a relatively common complication after left ventricular assist device (LVAD) implantation. Severe right heart failure can be managed by temporary right ventricular assist device (RVAD) implantation. However, trans-sternal RVAD insertion requires a subsequent third sternotomy for cannula removal. Herein, we present a case of RVAD insertion via a left anterior mini-thoracotomy after LVAD implantation in a patient with alcohol-induced cardiomyopathy.
5.Primary Chest Wall Sarcoma: Surgical Outcomes and Prognostic Factors
Ilkun PARK ; Sumin SHIN ; Hong Kwan KIM ; Yong Soo CHOI ; Jhingook KIM ; Jae Ill ZO ; Young Mog SHIM ; Jong Ho CHO
The Korean Journal of Thoracic and Cardiovascular Surgery 2019;52(5):360-367
BACKGROUND:
Primary chest wall sarcoma is a rare disease with limited reports of surgical resection.
METHODS:
This retrospective review included 41 patients with primary chest wall sarcoma who underwent chest wall resection and reconstruction from 2001 to 2015. The clinical, histologic, and surgical variables were collected and analyzed by univariate and multivariate Cox regression analyses for overall survival (OS) and recurrence-free survival (RFS).
RESULTS:
The OS rates at 5 and 10 years were 73% and 61%, respectively. The RFS rate at 10 years was 57.1%. Multivariate Cox regression analysis revealed old age (hazard ratio [HR], 5.16; 95% confidence interval [CI], 1.71–15.48) as a significant risk factor for death. A surgical resection margin distance of less than 1.5 cm (HR, 15.759; 95% CI, 1.78–139.46) and histologic grade III (HR, 28.36; 95% CI, 2.76–290.87) were independent risk factors for recurrence.
CONCLUSION
Long-term OS and RFS after the surgical resection of primary chest wall sarcoma were clinically acceptable.
6.Long-Term Outcomes of Modified Cone Reconstruction for Ebstein’s Anomaly in Pediatric Patients in a Single Center
Ilkun PARK ; Tae-Gook JUN ; Ji-Hyuk YANG ; I-Seok KANG ; June HUH ; Jinyoung SONG ; Ok Jeong LEE
Korean Circulation Journal 2024;54(2):78-90
Background:
and Objective: We aimed to investigate long-term clinical and echocardiographic outcomes, including tricuspid valve durability, annular growth, and left ventricular reverse remodeling, after modified cone reconstruction in patients with Ebstein’s anomaly.
Methods:
This was a retrospective analysis of all pediatric patients who underwent modified cone reconstruction for Ebstein’s anomaly at a single tertiary center between January 2005 and June 2021.
Results:
A total of 14 pediatric patients underwent modified cone reconstruction for Ebstein’s anomaly; the median age was 5.8 years (range, 0.01–16.6). There were three patients (21.4%) with Carpentier type B, ten patients with Carpentier type C (71.4%), and one patient with Carpentier type D (7.1%). There was no early or late mortality, arrhythmia, or readmission for heart failure at a 10-year follow-up. There were no cases of more than mild tricuspid stenosis or more than moderate tricuspid regurgitation during the study period, except for one patient with severe tricuspid regurgitation who underwent reoperation. The z value for tricuspid valve annular size significantly decreased immediately after the operation (2.46 vs. −1.15, p<0.001).However, from 1 year to 7 years after surgery, the z values were maintained between −1 and +1.Left ventricular end-systolic volume, end-diastolic volume, and stroke volume increased after surgery and remained elevated until seven years postoperatively.
Conclusions
Ebstein’s anomaly in children can be repaired by modified cone reconstruction with low mortality and morbidity, good tricuspid valve durability, and annular growth relative to somatic growth.
7.Long-Term Outcomes of Modified Cone Reconstruction for Ebstein’s Anomaly in Pediatric Patients in a Single Center
Ilkun PARK ; Tae-Gook JUN ; Ji-Hyuk YANG ; I-Seok KANG ; June HUH ; Jinyoung SONG ; Ok Jeong LEE
Korean Circulation Journal 2024;54(2):78-90
Background:
and Objective: We aimed to investigate long-term clinical and echocardiographic outcomes, including tricuspid valve durability, annular growth, and left ventricular reverse remodeling, after modified cone reconstruction in patients with Ebstein’s anomaly.
Methods:
This was a retrospective analysis of all pediatric patients who underwent modified cone reconstruction for Ebstein’s anomaly at a single tertiary center between January 2005 and June 2021.
Results:
A total of 14 pediatric patients underwent modified cone reconstruction for Ebstein’s anomaly; the median age was 5.8 years (range, 0.01–16.6). There were three patients (21.4%) with Carpentier type B, ten patients with Carpentier type C (71.4%), and one patient with Carpentier type D (7.1%). There was no early or late mortality, arrhythmia, or readmission for heart failure at a 10-year follow-up. There were no cases of more than mild tricuspid stenosis or more than moderate tricuspid regurgitation during the study period, except for one patient with severe tricuspid regurgitation who underwent reoperation. The z value for tricuspid valve annular size significantly decreased immediately after the operation (2.46 vs. −1.15, p<0.001).However, from 1 year to 7 years after surgery, the z values were maintained between −1 and +1.Left ventricular end-systolic volume, end-diastolic volume, and stroke volume increased after surgery and remained elevated until seven years postoperatively.
Conclusions
Ebstein’s anomaly in children can be repaired by modified cone reconstruction with low mortality and morbidity, good tricuspid valve durability, and annular growth relative to somatic growth.
8.Long-Term Outcomes of Modified Cone Reconstruction for Ebstein’s Anomaly in Pediatric Patients in a Single Center
Ilkun PARK ; Tae-Gook JUN ; Ji-Hyuk YANG ; I-Seok KANG ; June HUH ; Jinyoung SONG ; Ok Jeong LEE
Korean Circulation Journal 2024;54(2):78-90
Background:
and Objective: We aimed to investigate long-term clinical and echocardiographic outcomes, including tricuspid valve durability, annular growth, and left ventricular reverse remodeling, after modified cone reconstruction in patients with Ebstein’s anomaly.
Methods:
This was a retrospective analysis of all pediatric patients who underwent modified cone reconstruction for Ebstein’s anomaly at a single tertiary center between January 2005 and June 2021.
Results:
A total of 14 pediatric patients underwent modified cone reconstruction for Ebstein’s anomaly; the median age was 5.8 years (range, 0.01–16.6). There were three patients (21.4%) with Carpentier type B, ten patients with Carpentier type C (71.4%), and one patient with Carpentier type D (7.1%). There was no early or late mortality, arrhythmia, or readmission for heart failure at a 10-year follow-up. There were no cases of more than mild tricuspid stenosis or more than moderate tricuspid regurgitation during the study period, except for one patient with severe tricuspid regurgitation who underwent reoperation. The z value for tricuspid valve annular size significantly decreased immediately after the operation (2.46 vs. −1.15, p<0.001).However, from 1 year to 7 years after surgery, the z values were maintained between −1 and +1.Left ventricular end-systolic volume, end-diastolic volume, and stroke volume increased after surgery and remained elevated until seven years postoperatively.
Conclusions
Ebstein’s anomaly in children can be repaired by modified cone reconstruction with low mortality and morbidity, good tricuspid valve durability, and annular growth relative to somatic growth.
9.Totally Thoracoscopic Ablation in Patients With Recurrent Atrial Fibrillation After Catheter Ablation
Suk Kyung LIM ; Suryeun CHUNG ; Ilkun PARK ; Sang Ah CHI ; Kyunga KIM ; Kyoung-Min PARK ; Seung-Jung PARK ; Ju Youn KIM ; June Soo KIM ; Young Keun ON ; Dong Seop JEONG
Journal of Korean Medical Science 2023;38(39):e320-
Background:
The objective of this study was to evaluate the efficacy and safety of totally thoracoscopic ablation (TTA) in patients with recurrent atrial fibrillation (AF) after radiofrequency catheter ablation (RFCA).
Methods:
From February 2012 to May 2020, 460 patients who underwent TTA were classified into two groups: CA (presence of RFCA history, n = 74) and nCA groups (absence of RFCA history, n = 386). Inverse probability of treatment weighting (IPTW) analyses were used to adjust for confounders. The primary endpoint was freedom from the composite of AF, typical atrial flutter, atypical atrial flutter and any atrial tachyarrhythmia, lasting more than 30 seconds during the follow-up. All patients were followed up at 3, 6, and 12 months via electrocardiogram and 24-hour Holter monitoring.
Results:
Bilateral pulmonary vein isolation (PVI) was conducted in all patients and the conduction block tests were confirmed. In the CA group, difficult PVI occasionally occurred due to structural changes, such as pericardial adhesion and fibrosis of the pulmonary venous structure, caused by a previous catheter ablation. Early complications such as stroke and pacemaker insertion were not different between the two groups. The normal sinus rhythm was maintained in 70.1% (317/460) patients after a median follow-up period of 38.1 months.The IPTW-weighted Kaplan-Meier curves revealed that freedom from AF events at 5 years was 68.4% (95% confidence interval, 62.8–74.5) in the nCA group and 31.2% (95% confidence interval, 16.9–57.5) in the CA group (P < 0.001). In IPTW-weighted Cox regression, preoperative left atrial diameter, persistent or long-standing AF, the presence of congestive heart failure and catheter ablation history were associated with AF events.
Conclusion
Patients in the CA group showed a higher recurrence rate of AF than those in the nCA group, while TTA was safely performed in both the groups.