The use of thermogenic dietary supplements has led to growing concerns about potential adverse health effects. A 19-year-old female patient experienced recurrent blurred vision after consuming thermogenic dietary supplements for 5 weeks and eating only one meal per day. Initial brain imaging showed a lesion at the corpus callosum, which disappeared after a month, and her symptoms resolved within 2 days. The potential risks associated with using thermogenic dietary supplements in combination with intermittent fasting need to be carefully considered.