1.The effect of diltiazem on intrapulmonary shunt in dog under sevoflurane anesthesia.
Chong Sung KIM ; Il Young CHEONG
Korean Journal of Anesthesiology 1995;28(4):502-507
The effects of sevoflurane and subsequent administration of diltiazem on intrapulmonary shunt and oxygenation were studied in pentobarbital anesthetized dogs. After inhalation of 1MAC of sevoflurane and subsequent intravenous administration of clinical dose of diltiazem (loading dose 0.2 mg/kg, maintenance dose 0.01 mg/kg/min), there were no changes in cardiac output, arterial oxygen tension, mixed venous oxygen tension, oxygen transport, oxygen consumption, intrapul-monary shunt ratio, pulmonary vascular resistance, alveolar-arterial oxygen difference. After intravenous administration of diltiazem with bolus (0.4 mg/kg) and maintenance dose (0.02 mg/ kg/min), pulmonary vascular resistance was significantly decreased (p<0.05) but the other parameters indicating pulmonaruy hemodynamics and oxygenation were unchanged. These results suggest that concomittent use of the two classes of drugs is not induce significant changes in pulmonary hemodynamic and oxygenation, and can be used safely in patient with normal cardiopulmonary function when clinical concentration of both were used.
Administration, Intravenous
;
Anesthesia*
;
Anesthetics
;
Animals
;
Cardiac Output
;
Diltiazem*
;
Dogs*
;
Hemodynamics
;
Humans
;
Inhalation
;
Oxygen
;
Oxygen Consumption
;
Pentobarbital
;
Vascular Resistance
2.Continuous Arteriovenous Hemofiltration in Children.
Hae Il CHEONG ; Dong Kyu JIN ; Young Seo PARK ; Yong CHOI ; Kwang Wook KO
Journal of the Korean Pediatric Society 1989;32(2):230-238
No abstract available.
Child*
;
Hemofiltration*
;
Humans
3.Continuous Arteriovenous Hemofiltration in Children.
Hae Il CHEONG ; Dong Kyu JIN ; Young Seo PARK ; Yong CHOI ; Kwang Wook KO
Journal of the Korean Pediatric Society 1989;32(2):230-238
No abstract available.
Child*
;
Hemofiltration*
;
Humans
4.Renal Disease in Children-A Ten-Years Experience.
Hee Young SHIN ; Hae Il CHEONG ; Yong CHOI ; Kwang Wook KO
Journal of the Korean Pediatric Society 1983;26(7):681-686
No abstract available.
5.Recurrent Hematuria due to Renal Hypouricemia.
Kyu Young KIM ; Il Soo HA ; Hae Il CHEONG ; Yong CHOI
Journal of the Korean Pediatric Society 1995;38(1):129-132
A marked low concentration of serum uric acid(0.7-1.2mg/dl) was detected in a 14-year-old boy with recurrent episodes of gross hematuria. The hypouricemia accompanied with a markedly increased urinary clearance of uric acid (32.6-56.0ml/min), which was only minimally changed after both the administration of pyrazinamide, and inhibitor of the renal tubular secretion of uric acid, and the administration of probenecid, and inhibitor of the renal tubular reabsorption of uric acid. Other renal tubular functions were normal. There were no other family members with hypouricemia. Thies is the first case report of isolated renal hypouricemia due to presecretory reabsorption defect of uric acid in the renal proximal tubule in Korea. And renal hypouricemia should be included in the diagnosis of hematuria.
Adolescent
;
Diagnosis
;
Hematuria*
;
Humans
;
Korea
;
Male
;
Probenecid
;
Pyrazinamide
;
Uric Acid
6.The serum levels of estradiol, progesterone, and ?hCG in ectopic pregnancy.
Hi Young CHANG ; Young Soo KANG ; Young Ju KIM ; Eun Hee YOO ; Cheong Il KIM ; Bock Hi WOO
Korean Journal of Obstetrics and Gynecology 1993;36(7):1444-1451
No abstract available.
Estradiol*
;
Female
;
Pregnancy
;
Pregnancy, Ectopic*
;
Progesterone*
7.Effects of Body Temperature Changes on Hypoxic Pulmonary Vasoconstriction in Isolated Lungs of Rabbits.
Byung Moon HAM ; Il Young CHEONG
Korean Journal of Anesthesiology 1999;37(6):1117-1124
BACKGROUND: We studied the effects of body temperature changes and repeated hypoxic stimulation on hypoxic pulmonary vasoconstriction (HPV). METHODS: We isolated lungs from 15 rabbits and perfused them at a constant flow of 30 ml/kg/min with a 3% albumin-physiologic salt solution containing autologous blood. After a 30-minute stabilization, the temperature of the perfusate was changed from 38oC to 32oC gradually. The lungs were ventilated for 15 minutes with a hyperoxic gas mixture consisting of 95% oxygen and 5% carbon dioxide and then for 5 minutes with a hypoxic gas mixture consisting of 3% oxygen and 5% carbon dioxide with the balance being nitrogen. We repeated the hypoxic stimulation 3 times at the same temperature. The mean pulmonary artery pressure changes and ventilation-related parameters were measured at each hypoxic stimulation. RESULTS: With the first hypoxic stimulation, the hypoxic pressure response at the end of the 5-minute hypoxic period decreased significantly at 32oC. With the second and the third hypoxic stimulations, the hypoxic pressure responses at the end of the 5-minute hypoxic period decreased significantly at both 34oC and 36oC. With repeated hypoxic stimulations, the hypoxic pressure responses potentiated significantly at all temperatures. The baseline mean pulmonary artery pressure increased significantly below 34oC. CONCLUSION: The HPV decreased with the reduction in body temperature and was potentiated by repeated intermittent hypoxia; also, the pulmonary vascular resistance increased with the reduction in the body temperature.
Anoxia
;
Body Temperature Changes*
;
Body Temperature*
;
Carbon Dioxide
;
Lung*
;
Nitrogen
;
Oxygen
;
Pulmonary Artery
;
Rabbits*
;
Vascular Resistance
;
Vasoconstriction*
8.Antepartum fetal assessment based on fetal biophysical profile scoring in high risk pregnancies.
Young Ju KIM ; Ji A RYU ; Hye Sung MOON ; Hyn Mee RYU ; Kyung Hee CHOI ; Cheong Il KIM ; Bock Hi WOO
Korean Journal of Obstetrics and Gynecology 1993;36(7):2928-2943
No abstract available.
Pregnancy*
9.Clinical Studies on Total Anomalous Pulmonary Venous Connection.
Young Jin HONG ; Kee Hong KWON ; Hae Il CHEONG ; Jung Yeun CHOI ; Yong Soo YOON ; Chang Yee HONG
Journal of the Korean Pediatric Society 1982;25(11):1120-1130
No abstract available.
10.Analgesic Effect and Postoperative Cognitive Impairment of Patient Controlled Analgesia in Postoperative Elderly.
Ji Heui LEE ; Myung Won KIM ; Il Young CHEONG ; Ho Jo JANG
Korean Journal of Anesthesiology 1999;36(6):1017-1025
BACKGROUND: Since postoperative cognitive impairement is common in elderly patients and normal cognitive function is important for proper use of patient controlled analgesia (PCA), we compared the efficacy, adverse effect and postoperative cognitive impairment among postoperative elderly patients given the PCA morphine, fentanyl and meperidine. METHODS: Forty-five elderly patients were randomly allocated to receive patient-controlled analgesia with either morphine, fentanyl or meperidine following upper abdominal surgery. Patients were evaluated for used doses, adverse effects, visual analogue scale, the satisfaction for analgesia during postoperative 2 days and the Mini Mental Status Examination (MMSE) and the Short Portable Mental Status Questionnaire (SPMSQ) at posoperative 1 day. RESULTS: Patients receiving the PCA fentanyl used more opioid based on a dose expressed as morphine equivalents using the putative potency ratios of 1:10:0.01 (morphine/meperidine/fentanyl). But adverse effects, visual analogue scale, and the satisfaction for analgesia were not statistically different between groups. The decrease in MMSE in the PCA-meperidine group was significantly greater than that seen in the PCA-fentanyl group and the PCA-morphine group. SPMSQ were not statistically different between groups. CONCLUSION: The present result suggest that PCA is effective method in posterative elderly without serious complications. But PCA meperidine may be avoided in the elderly because it can contribute to decrease postoperative cognitive function.
Aged*
;
Analgesia
;
Analgesia, Patient-Controlled*
;
Fentanyl
;
Humans
;
Meperidine
;
Morphine
;
Passive Cutaneous Anaphylaxis