The anthors studied the 152 cases of primary bone tumors statistically during the period of 7 years and 4 months from Janusry, 1980 to April, 1987 at the department of orthopaedic surgery, St. Benedict Hospital, Pusan and the department of anatomic pathology, Pusan National University Hospital. The results of the study were summsrized as follows; l. Of the 152 cases of primary bone tumors, benign tumors were 128 cases(84.2%) and malignant tumors were 24 cases(15.8%). 2. Of benign bone tumors, the most common type was osteochondroms(34 cases, 26.6%), followed by fibrous dysplasia(25 cases, 19.5%), giant cell tumor(14 cases, 10.9%) and enchondroma(11 cases, 8.6%). 3. Of malignant bone tumors, the most common type was osteosarcoma(14 cases, 58.3%), followed by chondrosarcoma(5 cases, 20.8%), Ewing's sarcoma(3 cases, 12.5%) and myeloma(1 case, 4.2%). 4. Age distribution of benign bone tumors showed that most cases(76.4%) occured under 30-years old. Among malignant bone tumors, most of osteosarcoma and Ewing's sarcoma occured between 10-and 20-yesrs old. 5. The male to female ratio of overall benign bone tumors was 1.1: 1, and that of maligant bone tumors was 1.2: 1. There was no sexual difference. 6. The favorite sites of benign bone tumors were femur(31 cases, 23.1%), maxilla or mandible(31 cases, 23.1%), tibia(22 cases, 16.4%) and rib(11 cases, 8.2%) and those of malignant bone tumors were freguently femur(12 cases, 50.0%), followed by tibia(5 cases, 20.8 %) and pelvis(4 cases, 16.7%). 7. The most frequent manifestations in benign bone tumors were mass or swelling(62.7%), followed by pain or tenderness(33.9%) and disturbed motion or function(10.2%), but those were mostly pain or tenderness(73.9%), followed by mass or swelling(52.2%) and pathologic fracture(13.0%) in malignsnt bone tumors.8. The duration of symptoms in benign bone tumors was less than 6 months in 39.1% and less than 1 year in 44.6%, but less than 6 months in 70.9% and less than 1 year in 87.6% in malignant bone tumors. The duration of symptoms in malignant bone tumors was much shorted than that of benign bone tumors.
Age Distribution ; Busan ; Female ; Giant Cells ; Humans ; Male ; Maxilla ; Osteosarcoma ; Pathology ; Sarcoma, Ewing ; Statistics as Topic

The glucose uptake rate by plerocercoid of Diphyllobothrium sp. was a mean value of 5.35+/-0.80 micro-mole/hr/g of wet wt, and total CO(2) production rates by the plerocercoid larva averaged 7.54+/-0.73 micro-mole/hr/g of wet wt. The relative specific activity into respiratory CO(2) showed a mean value of 7.30 +/-0.90 per cent. The rate of CO(2) production derived from medium C(14)-glucose was a mean of 0.58+/-0.13 micro-mole/hr/g of wet wt. Therefore, the average value of 1.92+/-0.38 per cent of glucose utilized by the larvae from the medium C(14)-glucose was oxidized to respiratory CO(2). The tissue concentration of glycogen in plerocercoid larva was a mean of 46.28 +/-2.23 mg/g or 4.63+/-0.22 per cent/g of wet wt., and the turnover rate of glycogen pool was a mean of 0.049 +/- 0.012 %/hr or 0.010 +/- 0.003 mg/hr/g of wet wt. The average value of 2.76+/-1.00 per cent of glucose utilized by the larvae from the medium C(14)-glucose was incorporated to the glycogen. These data accounts for that only 5 per cent of the utilized glucose by the plerocercoid larvae participated in furnishing the oxidation into respiratory CO(2) and the synthetic process into glycogen.
parasitology-helminth-cestoda ; Diphyllobothrium sp. ; sparganum ; plerocercoid ; biochemistry ; autoradiography ; glucose ; metabolism ; CO(2)

No abstract available.
Female ; Fetal Blood* ; Humans ; Hypertension, Pregnancy-Induced* ; Infant, Newborn* ; Mothers* ; Pregnancy ; Pregnancy*

Soil-transmitted helminthiases (STH) are now no longer public health problems in the Republic of Korea (South Korea), but their status are unavailable in the residents of North Korea (NK) despite the expectation of large scale traffic and future reunification of the Korean Peninsula. A total of 20 female refugees from NK who had been admitted to the Division of Gastroenterology, Dankook University Hospital, were subjected in this study. Among them, 15 refugees were examined by the colonoscopy and 10 ones were examined with the stool examination (formalin-ether sedimentation). Both diagnostic methods were commonly adopted in 5 patients. Eggs of Trichuris trichiura were detected in 7 out of 10 refugees in the stool examination. In the colonoscopy, T. trichiura worms were found in 6 (40.0%) out of 15 refugees. Total 9 (45.0%) peoples were confirmed to be infected with human whipworms. Additionally, 1 case of clonorchiasis was diagnosed in the stool examination and a worm of Ascaris lumbricoides was discovered from a trichuriasis case. These findings suggested that STH is highly prevalent in NO, in which living conditions are not so good in the aspect of general hygiene and medical care.
Ascaris lumbricoides ; Clonorchiasis ; Clonorchis sinensis ; Colonoscopy ; Democratic People's Republic of Korea ; Eggs ; Female ; Gastroenterology ; Helminthiasis ; Helminths ; Humans ; Hygiene ; Ovum ; Public Health ; Refugees ; Republic of Korea ; Social Conditions ; Trichuriasis ; Trichuris

BACKGROUND: As the size of the elderly population has increased compared to the hole, there has been growing concern over potential health problems and geriatric hospitals for elderly people. However, despite the emerging needs for geriatric hospitals, there is no data on the clinical characteristics of patients being admitted to geriatric hospitals. To analyze the characteristics of elderly patients admitted to a geriatric hospital, we studied the medical records of patients admitted to Yong-in Hyoja Geriatric Hospital during a recent 20 months period. By clarifying the clinical characteristics of elderly patients admitted to a geriatric hospital, the basic data for understanding and treating elderly patients could be made. METHODS: We analyzed the medical records of 345 patients who were admitted to Yong-in Hyoja Geriatric Hospital from November 1997 to July 1999. The diagnosis of patients was largely subgrouped according to the existence of dementia, and subsequent detailed diagnoses were made. RESULTS: (1) The average age of patients was 74.59 years and there were slightly more females than males admitted (ratio, 1.15:1). (2) Most of the patients suffered from dementia (62.1%), of which vascular dementia was the most common(31.6%), followed by Alzheimer dementia(19.15%). (3) Compared to vascular dementia, patients with Alzheimer dementia had more severe cognitive dysfunction, psychosis, and agitation, while patients with vascular dementia had more problems in activities of daily living (ADL) and were more depressed than Alzheimer dementia (4) The average hospitalization duration was 3.54 months and incidence of significant illness after admission was 29.8%. The mortality rate was 10.9%. (5) The most common cause of death was infection (45.2%), followed by cardiovascular problems(16.2%). CONCLUSIONS: In addition to significant illnesses and mortality after admission, most patients admitted to geriatric hospitals have severe cognitive and behavioral problems. Therefore, adequate medical and neurological assessment and treatment for the aged is necessary.
Activities of Daily Living ; Aged ; Cause of Death ; Dementia ; Dementia, Vascular ; Diagnosis ; Dihydroergotamine ; Female ; Geriatrics ; Gyeonggi-do* ; Hospitalization ; Humans ; Incidence ; Male ; Medical Records ; Mortality ; Psychotic Disorders

No abstract available.

PURPOSE: We analyzed the surgical and functional outcomes of 100 consecutive laparo-scopic radical prostatectomies (LRP) performed by a single surgeon. MATERIALS AND METHODS: Between October 2007 and May 2010, a total of 100 consecutive patients underwent LRP for prostate cancer at our institution. We retrospectively reviewed the medical records of these patients to determine surgical and functional results. We compared surgical and functional outcomes between three groups divided on the basis of operation period (Group 1; first 40 cases; Group 2; next 30 cases; Group 3; last 30 cases). RESULTS: The operative time decreased significantly as the surgeon's experience increased over time (P<0.01). The learning curve for operative time was surpassed after approximately 40 cases. The overall positive surgical margin (PSM) rate was 17.5% in Group 1, 16.7% in Group 2, and 10% in Group 3. For organ-confined disease, the PSM rate was 2.5%, 6.7%, and 3.3% in Groups 1, 2, and 3, respectively. The continence rate (absence of a pad) was 73.2% and the social continence rate was 94.7% at 12 months after surgery. There was a significant difference in continence (absence of pad) between the early (Group 1) and late group (Group 3) at 1, 3, and 6 months (P<0.0001). The continence rate was not affected by whether the pubic bone-anchoring procedure or the Rocco suture method was used. The overall potency rate was 16.7% and 48.6% at 6 and 12 months, respectively. For bilateral nerve-sparing cases, the potency rate was 20% and 57.1% at 6 and 12 months, respectively. CONCLUSIONS: Our surgical and functional outcomes indicate that even in this 'robotic era', LRP is still an attractive treatment option for patients with localized prostate cancer, especially in areas with limited access to surgical robots.
Humans ; Laparoscopy ; Learning Curve ; Medical Records ; Operative Time ; Prostatectomy ; Prostatic Neoplasms ; Retrospective Studies ; Sutures ; Urinary Incontinence

BACKGROUND/AIMS: To prevent the transmission of pathogens by endoscopes, following established reprocessing guidelines is critical. An ideal reprocessing step is simple, fast, and inexpensive. Here, we evaluated and compared the efficacy and safety of two disinfectants, a tertiary amine compound (TAC) and ortho-phthalaldehyde (OPA). METHODS: A total of 100 colonoscopes were randomly reprocessed using two same automated endoscope reprocessors, according to disinfectant. The exposure time was 10 minutes for 0.55% OPA (Cidex® OPA, Johnson & Johnson) and 5 minutes for 4% TAC (Sencron2®, Bab Gencel Pharma & Chemical Ind. Co.). Three culture samples were obtained from each colonoscope after reprocessing. RESULTS: A total of nine samples were positive among the 300 culture samples. The positive culture rate was not statistically different between the two groups (4% for OPA and 2% for TAC, P=0.501). There were no incidents related to safety during the study period. CONCLUSIONS: TAC was non-inferior in terms of reprocessing efficacy to OPA and was safe to use. Therefore, TAC seems to be a good alternative disinfectant with a relatively short exposure time and is also less expensive than OPA.
Colonoscopes* ; Disinfectants* ; Endoscopes* ; o-Phthalaldehyde*

PURPOSE: Recently, the incidence of malignant melanoma has been steadily increasing. Malignant melanoma is already known to have poorer prognosis than other primary skin cancers. Despite the poor prognosis, it is relatively less known to the public so that a number of patients visit hospital carrying advanced stage tumor. Yet, extensive study about malignant melanoma is currently insufficient, and specific guidelines and statistical figures in Korea are almost inexistent. Therefore, authors reviewed patients with malignant melanoma who have visited our hospital for last 14 years. METHODS: Between January 1994 and January 2008, 62 patients were diagnosed with malignant melanoma at our hospital. A retrospective study was performed with data from patients' charts and biopsy results. Annual incidence, mean age of onset, gender, tumor location, tumor thickness, pathologic ulceration, clinicopathologic subtype, and clinical AJCC stage were evaluated. Analysis of factors associated with survival were performed using the Cox proportional hazard model. Kaplan-Meier method was used to generate survival curves. RESULTS: Clinicopathologic features of 62 patients (32 male, 30 female) with average age of 57 years were evaluated. Most lesions were found in lower limb, and the most common subtype was acral lentiginous melanoma. We could also find that age, tumor thickness, and clinical stage were the only significant prognostic factors. CONCLUSION: Clinicopathologic features of malignant melanoma were analyzed in this study, but the result is not ready to be generalized because of the limited number of cases. Further study must be performed to report clinical guidelines for prognosis and treatment for malignant melanoma patients in Korea.
Age of Onset ; Biopsy ; Humans ; Incidence ; Korea ; Lifting ; Lower Extremity ; Male ; Melanoma ; Prognosis ; Proportional Hazards Models ; Retrospective Studies ; Skin Neoplasms ; Survival Rate ; Ulcer

OBJECTIVE: To examine the changes of maternal mortality ratio and the causes of death in Korea during 1995-2000. METHODS: Maternal mortality data were collected through two stages: collection of registration data and maternal mortality survey at medical institutions. The cause of death was judged by agreement of three obstetrician. RESULTS: Maternal mortality ratio decreased from 20 (per 100,000 live births) in 1995 to 18 in 1999 and 15 in 2000. The mortality ratio was higher for women 35 years and older. Postpartum hemorrhage, hypertensive disorders of pregnancy, and obstetric embolism are three main causes of maternal death which comprised about half of all maternal death. CONCLUSION: Maternal mortality ratio decreased during 1995-2000. All causes of maternal death decreased since 1995. However obstetric embolism appeared to be relatively more important cause of death in 1999-2000.
Cause of Death* ; Embolism ; Female ; Humans ; Korea* ; Maternal Death ; Maternal Mortality* ; Mortality ; Postpartum Hemorrhage ; Pregnancy